(Beyond Pesticides, March 15, 2019) Beyond Pesticides and others have worked for many years to educate stakeholders and policy makers about the dangers of pesticides, and to transform pest management by eliminating a reliance on toxic pesticides and advancing organic management practices. Considerable focus has been on glyphosate, which is used in several herbicides, most notably in Bayer’s (then Monsanto’s, until its 2018 purchase by Bayer) Roundup. The compound has had a relatively high profile in the pesticide landscape, due in part to the ubiquity of its use, and in part to the tireless work of health and environmental advocates and scientists to expose its risks. With that profile, glyphosate has been a bit of a stand-in for the dangers of pesticides broadly. As journalist Carey Gillam said at Beyond Pesticides’ 36th National Pesticide Forum in 2018, “Glyphosate is the poster child for the bigger pesticide problem. . . . If it goes away tomorrow, we are [still] not okay.” The variety of risks this compound poses is broad, and pushback and risk evidence on its use come from multiple sides. This Daily News Blog focuses on recent developments on several of those fronts, all of which advanced knowledge and momentum, […]

(Beyond Pesticides, March 14, 2019) A study, supported by the USDA’s National Institute of Food and Agriculture, finds that state pesticide preemption laws “compromise public health and economic well-being” by preventing localities from enacting pesticide use restrictions on private property that are more restrictive than their state’s regulations. In the words of the authors, “By eliminating the ability of local governments to enact ordinances to safeguard inhabitants from health risks posed by pesticides, state preemption laws denigrate public health protections.” The study, Anti-community state pesticide preemption laws prevent local governments from protecting people from harm, published in the International Journal of Agricultural Sustainability, reviews scientific and historical evidence of the failure of state and federal pesticide laws to protect localities from pesticide poisoning, and highlights the inability of localities to compensate for that failure under present laws. Communities seeking to protect their residents would typically issue community-wide restrictions to ensure protection of shared community resources, including air, land, and waterways, from pesticide drift, runoff, and other nontarget effects —as is the case with other community decisions on recycling, smoking, and zoning. The study’s authors document how industry influence led to the adoption of state laws that undermine the ability of localities […]

(Beyond Pesticides, March 6, 2019) After a brief hiatus, Florida Fish and Wildlife Conservation Commission (FWC) is continuing use of aquatic herbicides, including glyphosate, for invasive species management. Public pressure and feedback caused FWC to take a temporary pause from spraying while the commission collected public comment  through public hearings and emails from late January through February. FWC ultimately decided to resume spraying invasive species, and points to its improved integrated management system as reducing overall herbicide use. Glyphosate, one of the 17 aquatic herbicides that FWC uses regularly has sparked opposition from environmentalists and the general public due to its wide usage and known adverse effects. According to FWC data, 12,263 pounds of glyphosate-based herbicides were used on Florida’s Lake Okeechobee in 2017. About 175,000 people have signed North Palm Beach photographer and wildlife advocate Jim Abernathy’s petition titled “Stop The State-Sanctioned Poisoning of Our Lakes and Rivers!”. The petition decries the use of glyphosate to kill invasive aquatic plants and warns of subsequent nutrient pollution caused by decay. An excess of nutrients (e.g. nitrogen and phosphorus) in water bodies contribute to algal blooms. Eutrophication can eventually result in oxygen depletion and thereby decrease biodiversity. FWC denies that the […]

(Beyond Pesticides, March 5, 2019) Wild, edible plants subject to drift from the herbicide glyphosate during forestry operations can be contaminated with the chemical an entire year after an initial application, according to a new study published in the Canadian Journal of Forest Research. Glyphosate is often used in forestry to knock down unwanted trees, shrubs, and other plants after clear-cutting to provide room for the regrowth of trees deemed valuable. However, this new research shows that “non-target” species, such as raspberries and blueberries, eaten by wildlife and sometimes wild foraged by humans can retain significant levels of glyphosate contamination due to drift and overspray. Forester Lisa Wood, PhD, from the University of Northern British Columbia began this research based on input and requests from Canadian indigenous First Nations communities. Back in 2013, shrubs foraged by traditional berry-pickers in northeastern British Columbia were sampled and found to contain glyphosate residues, leading to the need for a broader investigation. Dr. Wood sampled the roots and shoots of 10 plant species from an area that had been aerially sprayed with glyphosate a year prior as part of forestry operations to clear aspen and make room for coniferous re-plantings. The 10 plants, which […]

(Beyond Pesticides, February 28, 2019) Earlier this month, a team of U.S. scientists published a meta-analysis of studies on glyphosate-based herbicides (GBH), concluding that the evidence “suggests a compelling link between exposures to GBH and increased risk of NHL [non-Hodgkin lymphoma],” corroborating findings by the International Agency for Research on Cancer. The analysis, authored by researchers from University of California, Berkeley, University of Washington, Seattle, and the Icahn School of Medicine at Mount Sinai, New York, is the latest to support the conclusions established by the International Agency for Research on Cancer that products containing glyphosate pose a cancer risk to humans. As research continues to accumulate on the risks posed by this chemical, the case for transitioning to less toxic alternatives to safeguard public health is becoming increasingly urgent. Researchers took every available published human study on NHL and glyphosate, including the most recently updated data from the ongoing U.S. Agricultural Health Study (AHS), in conducting their review. Focus was put on individuals within these studies exposed to the highest amounts of glyphosate. The reasoning, researchers indicate, is that if there is a true association between glyphosate and a health outcome like cancer, exposures to higher amounts for a longer […]

(Beyond Pesticides, February 27, 2019) U.S. PIRG tested 20 common beers and wines and found glyphosate residues in all but one. Glyphosate, the active ingredient in Roundup, is the most commonly used agrichemical in the world. Though it is linked to many health and environmental issues, there is no current EPA limit for glyphosate residues in beer or wine. The U.S. Department of Agriculture (USDA) does not regularly test for glyphosate on either food or beverages. Researchers used an enzyme linked immunosorbent assay (ELISA) to detect glyphosate levels. Sutter Home Merlot had the highest level of glyphosate residues at 51 ppb (parts per billion). Barefoot Cabernet Sauvignon and Beringer Estates Moscato had slightly lower levels: 36.3 ppb and 42.6 ppb, respectively. Organic wines results were ~5 ppb. The beer samples had just slightly lower average levels of residues, the highest being Tsingtao beer with 49 ppb. Miller Lite, Corona, and Budweiser ranged from 25-30 ppb. Samuel Smith’s Organic Lager had a 5.7 ppb glyphosate concentration, and Peak Beer Organic IPA was the only sample with no detectable level of glyphosate. By U.S. Geological Survey (USGS) estimates, nearly 300 million pounds of glyphosate are annually applied to U.S. crops. Vineyards spray […]

(Beyond Pesticides, February 26, 2019) Breakfast cereal, apples, applesauce and pinto beans made and sold by Kroger contain residues of toxic pesticides linked to a range of series health and environmental problems, according to a residue study by Friends of the Earth. This is alarming. Kid-friendly food like applesauce and Cheerios should not contain dangerous pesticides. Kids are the most vulnerable to these pesticides and shouldn’t be exposed to brain-damaging or cancer-causing pesticides when they eat their breakfast or snacks. The connection between pesticides and cancer, learning disabilities, and other diseases is supported by hundreds of studies in Beyond Pesticides’ Pesticide-Induced Diseases Database. These new tests, which corroborate numerous residue studies, mean that Kroger customers may be purchasing food with the intent of providing safe and healthy food for their families, but end up unknowingly exposing them to toxic pesticides. Join the national week of action by either delivering a letter to Kroger in person, or sending an email to Kroger Chief Executive Rodney McMullen. The pesticides found in Kroger’s food are harmful to human health and pollinators. Friends of the Earth found residues of cancer-causing glyphosate, brain-damaging organophosphates, and bee-killing neonicotinoid pesticides. Organophosphates can cause damage to children’s developing brains, including reduced IQ, loss […]

(Beyond Pesticides, February 20, 2019) Women exposed to DDT during ‘early windows of susceptibility’ in their childhood are at increased risk of developing breast cancer, according to new research published in the Journal of the National Cancer Institute. Nearly 75 years after the chemical was first used in the U.S., and 50 years after its ban, DDT is continuing to adversely affect the health of Americans. The data brings needed attention to the dangers of early-life pesticide exposure, and underlines the need to take a precautionary approach to the introduction of biocides in our environment so that future generations do not suffer from the same mistakes of the past. “What we have learned is that timing really matters. We know that if harmful exposures occur at times when breast tissue is rapidly changing, such as during puberty, they impact breast development in ways that can later result in cancer,” said lead author Barbara A. Cohn, PhD, of the Public Health Institute’s (PHI) Child Health and Development Studies. “The research published today suggests that DDT affects breast cancer as an endocrine disruptor, that the period of time between first exposure and cancer risk seems to be around 40 years–and that other […]

(Beyond Pesticides, February 13, 2019) Friends of the Earth (FOE) released a report last week again showing pesticide residues in the food supply. The report, Toxic Secret, found store and name brand foods produced and sold by the top four U.S. food retailers — Kroger (NYSE:KR), Walmart (NYSE: WMT), Costco (NYSE:COST) and Albertsons — contain residues of toxic pesticides linked to a range of serious health and environmental problems. Among the pesticides found is the herbicide glyphosate, confirming residue testing results found in numerous studies. Glyphosate, the active ingredient in Roundup, has has been detected in popular foods, including “100% pure” honey, Doritos, Oreos, Goldfish, Ritz Crackers, German beers, California wines, and UK bread. Glyphosate has been ranked as potentially cancer causing in humans and adversely affects the human gut microbiome. See Residue Testing Find More Glyphosate in Popular Cereals. The FOE study finds that oat cereals, apples, applesauce, spinach and pinto beans at the retailers contained detectable amounts of glyphosate, organophosphates and neonicotinoids. The average level of glyphosate found in cereal samples (360 parts per billion) was more than twice the level set by scientists at Environmental Working Group for lifetime cancer risk for children. The average level of glyphosate found in pinto beans (509 ppb) was more […]

(Beyond Pesticides, February 6, 2019) The American Association for the Advancement of Science (AAAS) has awarded two researchers the group’s Scientific Freedom and Responsibility Award for their work uncovering the link between glyphosate and chronic kidney disease (CKD), which has killed at least 25,000 Sri Lankans and 20,000 Central Americans. Award recipients Sarath Guanatilake, MD, and Channa Jayasumana, PhD, faced death threats and claims of research misconduct as they went toe to toe with agrichemical industry giant Monsanto (now Bayer’s Monsanto), the major manufacturer of glyphosate-based products like Roundup. “To right a wrong when significant financial interests are at stake and the power imbalance between industry and individual is at play takes the unique combination of scientific rigor, professional persistence and acceptance of personal risk demonstrated by the two scientists recognized by this year’s award,” says Jessica Wyndham, director of the Scientific Responsibility, Human Rights and Law Program at AAAS. In the mid-90s, reports began to emerge of Sri Lankan rice farmers – many otherwise healthy, young adults, succumbing to CKD. Dr. Gunatilake, a researcher at California State University, Long Beach (CSULB), was hired by the Sri Lanka Ministry of Health to investigate the cause of the disease. Around the […]

(Beyond Pesticides, February 5, 2019) Linuron, an herbicide registered for use by the U.S. Environmental Protection Agency (EPA), yet recently banned in Europe due to health concerns, appears to trigger inflammatory signals that have been linked to the onset of Multiple Sclerosis (MS). This new evidence, published in the journal Cell by researchers at Brigham and Women’s Hospital in Boston, MA, indicates that exposure to chemicals and pesticides in the environment may be a risk factor in the development of neurodegenerative diseases. “We created a platform to systematically investigate the understudied effects of environmental exposures,” said study coauthor Francisco Quintana, PhD. “The goal of our work is to return results that can guide future epidemiological studies and identify actionable targets.” Researchers began their investigation with 976 chemicals identified by EPA’s ToxCast program, an inventory of compounds that have undergone screening for a battery of laboratory tests. Within that inventory, 75 chemicals, including linuron, were found to interfere with the signaling pathways linked to MS. To confirm the adverse impacts, scientists used the embryos of zebrafish, animals often used as models in laboratory research. The zebrafish embryos were altered to contain low levels of myelin, a protein that protects nerve cells, as […]

(Beyond Pesticides, February 1, 2019) Prior to a pesticide ban taking effect in Montgomery County Maryland Parks, the Department of Parks announced in mid-December 2018 that it would discontinue the use of glyphosate-based herbicides through March 2019. The agency has used these hazardous herbicides as part of its IPM (Integrated Pest Management) program for weed management. Montgomery Parks indicates it will release further information on the use of glyphosate in mid-March. In November last year, Montgomery County Council member Tom Hucker wrote to the head of Parks, supported by a community-wide petition, urging that glyphosate be banned immediately, pending implementation of the county ban. He cited the finding of the International Agency for Research on Cancer’s (World Health Organization) finding that the chemical probably causes cancer in humans and the $289 million jury verdict last year that the chemical caused a school groundskeeper’s non Hodgkin lymphoma. In 2016, Montgomery Parks instituted a pesticide reduction program in compliance with Montgomery County, Maryland’s 2015 adoption of County Code 33B, which aimed to regulate use of pesticides on county-owned property, including parks, and on private property. In 2017, a Montgomery Circuit Court overturned the portion of the law pertaining to a ban on private […]

(Beyond Pesticides, January 29, 2019) After eight months of deliberation and discussion, the European Parliament’s Special Committee (the PEST Committee) overwhelmingly approved its draft report in early December 2018 with recommendations to strengthen pesticide restrictions. PEST was established in January 2018 to assess the European Union’s authorization procedure for pesticides. The group’s charge was to review the European Union’s (EU’s) pesticide authorization process, identify its failures in evaluating and approving pesticides and their use (including any conflicts of interest impacting the process), and make recommendations to improve the protection of human, animal, and environmental health from pesticides. The 30-member committee concluded: improvement of the system will require changes in the entirety of the pesticide approval process — from the point of industry application for authorization of a pesticide, to the sale and use of any products containing the compound in EU Member States, to evaluation of impacts of its use once on the market. The approval, sale, use, and regulation of what the EU calls “Plant Protection Products” [PPP] — active substances used to “1) to protect plants or plant products against pests/diseases, 2) to influence the life processes of plants (such as substances influencing their growth, excluding nutrients) and […]

(Beyond Pesticides, January 18, 2019) A new analysis by Charles Benbrook, PhD, published in the journal Environmental Sciences Europe, adds to the chronicle of the failures of the U.S. Environmental Protection Agency (EPA) to protect human health from toxic pesticides, and in this subject instance, from glyphosate. Meanwhile, a French Court has pulled the license for a Roundup product, citing the French government’s failure to protect public health. In his paper, Dr. Benbrook examines the divergent positions on the carcinogenicity of glyphosate — the active ingredient in a number of herbicides, most notably Monsanto’s (now Bayer’s) Roundup — taken by the International Agency for Research on Cancer (IARC) and by EPA. The paper calls out EPA’s handling of science related to the safety of glyphosate, suggesting that the agency has discounted evidence of the compound’s association with genotoxicity — destructive effects on cellular genetic material that can cause mutations — which can result in cancer. Dr. Benbrook is an American agricultural economist, former executive director of the National Academy of Sciences board on agriculture, and former research professor at the Center for Sustaining Agriculture and Natural Resources at Washington State University. He has long studied pesticide use related to genetically engineered […]

(Beyond Pesticides, January 16, 2019) Preliminary counts in California indicate the western monarch butterfly population dropped 86% from 2017 to 2018. The survey is a result of an annual effort by volunteer citizen scientists, organized by the nonprofit organization Xerces Society. If the trend from the initial sample (97 sites) holds true, the population of overwintering butterflies is estimated to be less than 30,000 – 0.05% of its historical size. Full and vetted results will be published in late January. To get an accurate count of monarch populations, volunteers follow a monitoring guide, which recommends beginning a count on a still, cool, and dry morning so that monarchs are still clustered together. Volunteers count a small cluster of monarchs and then extrapolate that number to arrive at a total for the larger cluster they’re observing. Citizen science has been crucial to understanding the decline of monarchs and insects worldwide. As covered by The New York Times, the current “Insect Apocalypse” has largely been documented by volunteers. The dismal numbers recorded this year are potentially disastrous, as the predicted extinction threshold for overwintering western monarchs is a population of 30,000. However this threshold, based on population densities needed for thermoregulation and mating […]

(Beyond Pesticides, January 14, 2019)  A petition submitted on January 7 by the Center for Biological Diversity calls on the National Marine Fisheries Service (NMFS) and the U.S. Fish and Wildlife Service (FWS) to initiate rulemaking to proscribe nearly all pesticide use in areas that are deemed critical habitat for endangered species. It asks these federal agencies to use the authority they have under the 1973 Endangered Species Act (ESA) to protect wildlife from the threats represented by pesticides — which threats both agencies have long recognized. The language of the ESA says its purpose is “to provide a means whereby the ecosystems upon which endangered species and threatened species depend may be conserved.” In its press release on the petition, the Center for Biological Diversity (CBD) notes that it comes “after decades of intransigence by the Environmental Protection Agency, which has refused to comply with the legal mandates of the Endangered Species Act to protect the nation’s most imperiled species from highly toxic pesticides like chlorpyrifos and atrazine that are known to harm wildlife.” CBD environmental health director Lori Ann Burd said, “Pesticides pose a devastating danger to endangered wildlife, from coast to coast. If the EPA isn’t going to […]

(Beyond Pesticides, January 8, 2019) At the end of December, the U.S. Department of Agriculture (USDA) finalized its rule regarding the disclosure of genetically engineered (GE) ingredients in consumer foods. After years of local, state and federal pressure to implement a clear, concise labeling requirement for GE foods, advocates say USDA’s rule is a failure, and a capitulation to agrichemical corporations that promote GE farming systems. According to U.S. Representative Chellie Pingree (D-ME), speaking with the Portland Press Herald, the new rule is “an insult to consumers.” She said, “These labels should give people the facts of whether ingredients in their food have been genetically altered, plain and simple.” Rather than the plain and simple language urged by Rep Pingree and other GE labeling advocates, USDA determined to move forward with muddled verbiage that is certain to confuse consumers. GE products will not defined by a term Americans are familiar with, such as GE or GMO. Instead, the term USDA will require on product labels is “bioengineered.” USDA is allowing companies to choose one of the following methods to alert consumers to the presence of GE ingredients in their foods: Inclusion of a “bioengineered” or “derived from bioengineering” symbol alongside […]

(Beyond Pesticides, December 21-31, 2018)  As we look ahead to the new year, we wish you good health, extend our appreciation for your being a part of the Beyond Pesticides network, and ask you to consider a contribution to Beyond Pesticides. Your support is critical to our program and deeply appreciated. We approach the new year with a sense of optimism that we will advance our collective will to solve devastating environmental problems. We believe it can be done! But, it takes us all joining together with a strong voice and unified action to stop hazardous practices, while putting safe and sustainable alternatives in place. With your support of Beyond Pesticides, we strive to reverse the destructive environmental and public health path that we’re on. As a grassroots organization, we work with community-based campaigns and organizations to put organic land management practices in place—in our parks, on playing fields, school grounds, and throughout communities. Together, we eliminate practices that contaminate waterways, put poisons in the air, degrade and destroy life in the soil, and expose us to pesticides that cause or contribute to a range of dreaded diseases like cancer—Parkinson’s, diabetes, reproductive disorders, autism, and more. We can change the current course—take the glyphosate/Roundup out […]

(Beyond Pesticides, December 18, 2018) The ingredients not listed on a pesticide product are not fully reviewed for their adverse effects may be the most toxic chemicals in the formulation. Recent research, Toxicity of formulants and heavy metals in glyphosate-based herbicides and other pesticides (Toxicology Reports 5, 2018), by Defarge, de Vendômois, and Séralini demonstrates the need to disclose and test all ingredients in pesticide products, as well as the full formulation that includes “inert” or nondisclosed ingredients. While glyphosate/Roundup is obviously not allowed to be used in organic production, this research reaffirms the need to evaluate full formulations of substances allowed for use in organic. The research on glyphosate tested the toxicity of the herbicide glyphosate, “inerts” in glyphosate-based herbicides (GBH), and the pesticide formulations–looking at toxicity to target organisms, toxicity to human cells, and endocrine-disrupting activity. In addition to the GBH products, the researchers studied a number of other pesticides. Tell NOP and USDA that “inerts” used in organic production must receive full review by the NOSB. “Inert” ingredients are allowed in pesticides used in organic production as well as those used in chemical-intensive production. The National Organic Program (NOP) allows “inerts,” permitted in conventional production and formerly listed […]

(Beyond Pesticides, December 13, 2018) The U.S. is pushing back against international standards that restrict pesticides by appealing to the World Trade Organization (WTO) to intervene. At issue are new EU maximum residue levels (MRLs) on food for the following pesticides: buprofezin, diflubenzuron, ethoxysulfurom, ioxynil, molinate, picoxystrobin and tepraloxydim. Advocates are concerned that a U.S. challenge to stronger EU standards could cause the WTO to force a weakening of standards internationally. Most significantly, EU proposed lowering its MRLs on imports. The EU said lower MRLs are needed to protect consumers, as research shows pesticides are shown to be carcinogenic, and that, contrary to chemical-industry claims, no level of allowable exposures can be assumed. Taking issue with the new MRLs – as with all other STCs mentioned above – the U.S. said new MRLs would cause barriers to trade, and therefore, must be rejected by the WTO. Advocates point to the introduction of GMOs as an example of the U.S. using the WTO to block standards that restrict potentially hazardous products. Recently, the U.S. has been involved in four of five new specific trade concerns (STCs) raised before WTO. As part of reviewing the current agreement of the Committee on Sanitary and Phytosanitary […]

(Beyond Pesticides, November 30, 2018) A study published this month in Science of the Total Environment reveals numerous pesticide residues persisting in soil, harming the viability of agricultural lands and increasing risk of off-site contamination. Funded by the Horizon 2020 programme of the European Commission, researchers from the European Diverfarming project at the University of Wageningen in the Netherlands suggest nations urgently reevaluate conventional land use and inputs including water, energy, fertilizers, machinery and pesticides. Researchers decrying the lack of soil protection policies endeavored to determine which pesticides had the highest soil persistence and toxicity to non-target species. Three hundred seventeen surface soil samples were analyzed from 11 European countries. Selected countries were those with the largest amounts of active agricultural land, characterizing six distinct cropping systems. Sampled soils purposefully represented different soil properties and were taken from crops with the highest pesticide use per hectare. Samples were then analyzed for the concentration of 76 pesticide residues. These 76 pesticides were selected as being most often applied on conventional crops. Eighty-three percent of samples contained varying degrees of pesticide residues, with 25 percent showing one pesticide residue and 58 percent showing mixtures of two or more. Only 17 percent of […]

(Beyond Pesticides, November 27, 2018) The U.S. Environmental Protection Agency (EPA) ignored the input of an expert weed scientist on the controversial herbicide dicamba, bending to Bayer’s Monsanto and the pesticide industry, according to emails obtained by the Arkansas Democrat and Chronicle (ADC) through a Freedom of Information Act request. The scandal centers on the recent re-approval of the pesticide, a highly volatile and drift-prone herbicide that has become a serious problem for many farmers and state regulators. As top-level EPA officials continue to work with industry to subvert their own agency’s scientific findings, more and more consumers are moving to organic products in order avoid the pesticide risks government regulators ask consumers to accept. Emails ADC received indicate that Jason Norsworthy, PhD, a weed scientist with the University of Arkansas, worked closely with Bayer’s Monsanto in conducting field trials this past summer, but found high volatility and drift of the company’s new dicamba-based herbicide XtendiMax. The product was developed in the face of widespread resistance to glyphosate-based herbicides in genetically engineered (GE) farm fields. However, recent accounts from farmers in the south and midwest indicate that, not only is the switch to dicamba unhelpful  in eliminating drift and reversing escalating weed resistance, its […]

(Beyond Pesticides, November 20, 2018) Scientific conclusions used to support the registration of the insecticide chlorpyrifos were flawed and omitted key health impacts, according to a fresh analysis of the original data by a team of independent scientists from northern Europe and the U.S. This re-review not only casts further doubt on the safety of the neurotoxic chlorpyrifos, it highlights a major flaw within federal pesticide regulation that allows pesticide producers to submit their own safety evaluations to the U.S. Environmental Protection Agency without public oversight. “One conclusion we draw is that there is a risk that the results of industry-funded toxicity tests are not reported correctly,” says co-author Axel Mie, PhD. “This makes it difficult for the authorities to evaluate the pesticides in a safe and valid way.” In both the U.S. and European Union, pesticide producers contract with laboratories to perform required safety tests of active ingredients they hope to register for use. While these studies are generally considered ‘confidential business information’ and not available to the public, using Swedish freedom of information laws, researchers were able to obtain two key studies relating to the developmental neurotoxicity of chlorpyrifos. Although not disclosed within the study, it is well […]