(Beyond Pesticides, July 22, 2019) The U.S. Environmental Protection Agency (EPA) will permit the continued use of a known neurotoxic insecticide on the food the Americans eat, the agency announced yesterday in response to a lawsuit filed by public health groups. Health advocates say the move to continue chlorpyrifos use is the latest example of the agency working to protect the profits of industry over the health of Americans. “By allowing chlorpyrifos to stay in our fruits and vegetables, Trump’s EPA is breaking the law and neglecting the overwhelming scientific evidence that this pesticide harms children’s brains,” said Patti Goldman, an attorney for Earthjustice. “It is a tragedy that this administration sides with corporations instead of children’s health.” Under a lawsuit filed in the 9th Circuit US Court of Appeals, EPA had 90 days to provide a justification for why the pesticide should remain on the market. EPA denied the petition yesterday, and rather than providing positive justification for continued use of the chemical, attacked the sound science claimants urged the agency to consider as “not…valid, complete, and reliable.” In the absence of EPA action, several states are leading in the protection of their residents by rejecting the agency’s determination regarding […]

(Beyond Pesticides, May 1, 2019) Evidence of the dangers of glyphosate continues to mount: researchers at Washington State University have identified, in research that exposed pregnant rats to the compound, significant disease and pathology in subsequent generations. The rats were exposed, from day 8 through day 14 of gestation, to half the observable adverse effect level (NOAEL) of glyphosate. Although this study found negligible impacts on the pregnant rats themselves or on their first-generation offspring, dramatic increases in incidence of pathology showed up in the two subsequent generations, including reproductive (prostate and ovarian) and kidney diseases; obesity; and birth anomalies. The study, published in the journal Scientific Reports (an open access, multidisciplinary journal from Nature Research), and conducted by Michael Skinner, Ph.D. and five colleagues, is the first to assess the potential transgenerational impacts of glyphosate in mammals. Its results point to an emerging frontier in assessing the risks of glyphosate and other toxic chemicals, and add to the urgent and growing demand that the use of this particular toxic — and pervasive — pesticide be halted. The research team was interested in looking at possible transgenerational impacts of glyphosate in part because of its ubiquity: it is one of the […]

(Beyond Pesticides, March 27, 2019) Exposure to commonly used pesticides in the womb and during the first year of life is linked to a higher risk of developing autism, according to the study, “Prenatal and infant exposure to ambient pesticides and autism spectrum disorder in children: population based case-control study,” published in the journal BMJ last week. Although the study does not reveal a causal link, it adds to previous literature highlighting autism risks from pesticide exposure, and reinforces calls to limit pesticide exposure during early life critical windows of vulnerability. The authors note their findings “support the need to avoid prenatal and infant exposure to pesticides to protect the developing child’s brain.” Researchers used data from California’s records of autism disorder diagnosis and birth rates from 1998 to 2010. Roughly thirty-five thousand healthy patients acted as a control, while scientists identified nearly three thousand patients with an autism diagnosis, of which 445 also displayed a co-occurring intellectual disability. Data was then drawn from California’s pesticide use recording database, and eleven pesticides (glyphosate, chlorpyrifos, diazinon, acephate, malathion, permethrin, bifenthrin, methyl bromide, imidacloprid, avermectin, and myclobutanil) were analyzed for their use within 2000 meters (1.25 miles) of the homes of those […]

(Beyond Pesticides, December 6, 2018) A recent analysis of annual drinking water quality reports has revealed that many community drinking water systems in the Midwest have seasonal exceedances of the allowable limit for the herbicide atrazine. Atrazine, linked to endocrine disruption, neuropathy, and cancer, is the second most widely used pesticide in corn growing areas, with over 73 million pounds applied to agricultural fields each year.  A 2009 study by Paul Winchester, MD, professor of clinical pediatrics at Indiana University School of Medicine and a neonatologist at St. Francis Hospital in Indianapolis, linked birth defects to time of conception, with the greatest impact on children conceived when concentrations of atrazine and other pesticides are highest in the local drinking water. (See Reproductive Effects Peak with Pesticide Exposure.) During peak use, atrazine levels in drinking water have been recorded at three to seven times above the legal limit. In addition to the well documented impact on the environment, recent  studies have linked prolonged pesticide exposure to not only shortened gestation and preterm birth for women, but also neurodevelopment delays in children. Ultimately, these unreported seasonal peaks may result in persistent adverse health impacts in impacted communities. The Safe Drinking Water Act (SDWA), enacted in 1974, […]

(Beyond Pesticides, November 1, 2018) A new study offers fresh evidence that wild bumblebee pollinators are particularly vulnerable to the impacts of neonicotinoid (neonic) insecticides, finding that exposure to these compounds interferes with mating success and population stability. Researchers from Worcester Polytechnic Institute in Massachusetts, measuring real-world harms of neonicotinoids, indicate that the impacts they found to bumblebee “reproducers,” namely queen and drone (male) bees, does not bode well for the array of plant species that relies on them. Though advocates warn that destabilizing managed pollinators could threaten U.S. food production and exports, with food prices increasing as cost of bringing pollinators to farms increases, the study’s authors and advocates insist that the impacts of such widespread poisoning of wild bees could be felt well beyond agriculture. Researchers in the lab compare behavioral and psychological responses of virgin queens, workers, and male Bombus impatiens from multiple colonies to field-realistic doses of the neonicotinoid clothianidin. While every bee was given a replenishing supply of pollen based on body weight and energy demands, four distinct concentrations of diluted analytical-grade (pure) clothianidin (including a control with no pesticide added) were mixed into a nectar-like solution and fed to the bumblebees orally for 5 […]

(Beyond Pesticides, October 22, 2018) The California Department of Pesticide Regulation (DPR) is accepting comments on its proposal to classify chlorpyrifos as a toxic air pollutant. The classification would require DPR to develop control measures that adequately protect public health. What happens in California affects all of us because products of California agriculture are available all over the country –and the world. In addition, policies set by the state of California are often examples for other states and the federal government. Tell California Department of Pesticide Regulation to ban chlorpyrifos. California’s Office of Environmental Health Hazard Assessment (OEHHA) states: Under the Toxic Air Contaminant Identification and Control Act (AB 1807, Chapter 1047, Statutes of 1983) and its implementing regulations (Title 3, California Code of Regulations, Section 6864), one of the criteria for identifying a pesticide as a TAC is if its concentration in the air exceeds one-tenth of the level that has been determined to be adequately protective of human health. The draft TAC document shows that bystanders can be exposed to modeled air concentrations of chlorpyrifos that exceed one-tenth the protective level, and thus meet the criteria for TAC identification. OEHHA’s findings below serve to reinforce this overall conclusion, and […]

(Beyond Pesticides, August 22, 2018) Mothers with high levels of DDT’s major metabolite, DDE, are more likely to have their children diagnosed with autism, according to a study published in The American Journal of Psychiatry this month. Though this study links autism to long-banned DDT, it raises significant concerns about legacy contamination from this chemical, which remains ubiquitous in the environment and in human bodies. With an increasing number of studies linking autism and other developmental disabilities to pesticides, the need to transition to safer, organic methods of farming is now more important than ever before. The study, Association of Maternal Insecticide Levels With Autism in Offspring From a National Birth Cohort, measured maternal serum levels of Finish women during early pregnancy whose children were born between 1987 and 2005. Specimens were analyzed for DDE as well as PCB contamination. Mothers with DDE at the highest 75% threshold reportedly had a 132% (1.32x odds ratio) increased risk of having a children diagnosed with autism after adjusting for confounders such as age and history of psychiatric disorders. Moms above the 75th percentile had their chances of a child’s autism diagnosis increase by 221% (2.21x odds ratio). The study found no connection […]

(Beyond Pesticides, May 3, 2018) Hawaii’s bill to ban the dangerous, neurotoxic pesticide, chlorpyrifos, passed its final hurdle this week in the state legislature. Governor David Ige is expected to readily sign SB3095 into law, in light of the unanimous support it received from lawmakers on both sides of the aisle. The statewide prohibition of chlorpyrifos will take effect beginning in January 2019. This legislative action marks the first time that any state in the country has passed an outright ban on the highly toxic organophosphate pesticide. While multiple scientific studies have determined that chlorpyrifos damages fetal brains and produces cognitive and behavioral dysfunctions, particularly in utero and in children, states have been slow to institute a complete prohibition, due to its widespread use in agriculture. Lawmakers in New Jersey and Maryland have recently tried unsuccessfully to pass similar bans. Hawaii’s bill contains a caveat that allows the state’s Department of Agriculture (DOA) to grant special permits for companies that argue that they need more time to phase-out chlorpyrifos, but that exemption will end at the close of 2022. The new law also requires restricted use pesticide (RUP) users to report to the Hawaii’s DOA which ones they are applying on […]

(Beyond Pesticides, March 21, 2018) According to a new study published this month in Environment Health, women with high levels of glyphosate in their bodies are more likely to have shorter pregnancies. Shorter pregnancies can lead to children with reduced learning and brain development. This is the first study to suggest that exposures to glyphosate can influence the long-term well-being of children. The study, Glyphosate exposure in pregnancy and shortened gestational length: a prospective Indiana birth cohort study, obtained both urine and drinking water samples from 71 women with pregnancies living in Central Indiana while they received routine prenatal care, and analysed the relationships of glyphosate levels in mother’s urine with fetal growth indicators and gestational length. The researchers found that more than 90 percent of pregnant women had detectable levels of glyphosate where higher glyphosate levels were significantly correlated with shortened gestational lengths, even though the drinking water samples had little to no detectable levels of glyphosate. Women living in rural areas were found to have higher glyphosate levels. The authors note their study is significant because it is the first U.S. study designed specifically to measure prenatal glyphosate exposure in pregnant women to determine its association with adverse fetal […]

(Beyond Pesticides, September 14, 2017) Children whose mothers took folic acid while pregnant had a significantly lower risk of developing autism spectrum disorder (ASD) even when their mothers were exposed to household or agricultural pesticides. Researchers at the University of California, Davis found that taking folic acid during the window around conception, reduced the risk of pesticide-induced autism. In the study, “Combined Prenatal Pesticide Exposure and Folic Acid Intake in Relation to Autism Spectrum Disorder,” children whose mothers took 800 or more micrograms of folic acid (the amount in most prenatal vitamins) had a significantly lower risk of developing autism spectrum disorder, even when their mothers were exposed to household or agricultural pesticides that are associated with increased risk. The study used data from the Childhood Autism Risks from Genetics and the Environment (CHARGE) study, where researchers looked at 296 children between 2 and 5 who had been diagnosed with ASD and 220 who had developed typically. Mothers were interviewed about their household pesticide exposure during pregnancy, as well as their folic acid and B vitamin intake. The team also linked data from California Pesticide Use reports, which provided important details about agricultural spraying, with the mothers’ addresses. The results […]

(Beyond Pesticides, August 31, 2017) Researchers at the University of California, Santa Barbara report in a new study that exposure to pesticides as a result of living near agricultural areas increases the risk of giving birth to a baby with abnormalities. These results are more significant for those exposed to very high levels of pesticides, underscoring the continued risks faced by farmworkers and farmworker families, especially mothers living near chemically-intensive treated fields. The study, “Agricultural pesticide use and adverse birth outcomes in the San Joaquin Valley of California,” looked at individual birth and demographic characteristics for over 500,000 birth observations between 1997 and 2011 in the agriculturally dominated San Joaquin Valley, California. The researchers, who report their findings as, “the most comprehensive to date, bringing together the largest data file ever compiled on street-address level birth outcomes and fine scale exposure to agricultural pesticides,” analyzed residential agricultural pesticide exposure during gestation, by trimester, and by toxicity influences on birth outcomes: birth weight, gestational length, or birth abnormalities. Adverse birth outcomes increased by 5–9% among those exposed to very high quantities of pesticides (e.g., top 5th percentile, i.e., ~4,200 kg per square mile applied over gestation). According to the results, “ The magnitude of effects were further enlarged […]

(Beyond Pesticides, June 21, 2017) More than 200 international scientists and medical professionals have signed the Florence Statement on Triclosan and Triclocarban, which states that triclosan and its chemical cousin triclocarban pose a risk to human health, and urges the international community to limit use of these antimicrobials, which are associated with bacterial resistance and no more effective than soap and water. In 2016 after manufacturers failed to prove efficacy, the U.S. Food and Drug Administration (FDA), which regulates cosmetic triclosan products, announced that manufacturers must, by September 2017, remove triclosan from over the counter hand soaps. The agency still allows the chemical in toothpastes and other products, such as hand wipes. The Environmental Protection Agency (EPA), which regulates triclosan in household items, textiles and plastics, still permits wide use of the chemical in a range of products. The Florence Statement on Triclosan and Triclocarban is “based on extensive peer-reviewed research,” and “concludes that triclosan and triclocarban are environmentally persistent endocrine disruptors that bioaccumulate in and are toxic to aquatic and other organisms.” The statement includes evidence of human health threats, and provides recommendations intended to mitigate harm from triclosan, triclocarban, and other similar antimicrobials. The recommendations are listed below: “Avoid […]

(Beyond Pesticides, June 15, 2017) Communities exposed to frequent aerial spraying for mosquito control experience elevated rates of autism diagnoses, according to new research. The study identifies the frequent use of synthetic pyrethroid insecticides, which are linked to neurocognitive and behavioral impacts, among other health effects. Pediatric researchers at Penn State University and the University of California examined communities in eight zip codes in Onondaga County, New York with frequent aerial spray programs for mosquito control, and contrasted these findings with communities in 16 zip codes that do not employ similar pesticide use programs. According to the study, between 2007 and 2009, the average yearly pesticide burden across the eight aerial exposed zip codes was approximately 11,000 kilograms, compared to approximately 4,000 kilograms of pesticide exposure across the 16 control zip codes. The study finds that the zip codes with frequent aerial pyrethroid exposure are 37% more likely to have higher rates of childhood developmental delays and autism spectrum disorder. The researchers acknowledge that the study establishes a correlational, not a causal, link between pyrethroid exposure and autism/developmental disorders, it adds to a growing body of research demonstrating an exposure-effect relationship between the two. Other studies have similarly linked developmental disorders and autism […]

(Beyond Pesticides, June 8, 2017) On Monday, numerous organizations filed an administrative appeal to the U.S. Environmental Protection Agency (EPA), seeking to reverse Scott Pruitt’s order to continue allowing the toxic organophosphate insecticide chlorpyrifos in agriculture, and revoke all tolerances (allowed food residues) of the chemical. On the same day, Attorneys General (AGs) from seven states announced legal objections to Scott Pruitt’s order, also calling for a reversal of the decision and a revocation of all tolerances. Allowing the continued use of chlorpyrifos runs counter to findings of independent science and EPA’s own scientists, which establish unacceptable risks to humans and the environment. The administrative appeal, filed by Earthjustice on behalf of 12 environmental, labor, and civil rights organizations, resulted from the decision by EPA to allow the use of chlorpyrifos while it studies the safety of the chemical. The seven AGs, in their filing, are charging that EPA wrongfully approved the continued use of chlorpyrifos in agriculture without first gathering and assessing the full safety data, as required by the U.S. Food, Drug, and Cosmetic Act. Many environmental groups spoke out in favor of these filings. “There’s a good reason this dangerous toxin has been banned from indoor use for more […]

(Beyond Pesticides, June 2, 2017) According to a new study, levels of triclosan spike in the bodies of children after they brush their teeth or wash their hands. Triclosan, a controversial antimicrobial, is frequently added to consumer care products. Last year, the Food and Drug Administration (FDA) banned the use of triclosan in hand soaps, but it is still allowed in toothpaste and numerous plastic and textile products regulated by the U.S. Environmental Protection Agency (EPA). Many companies had previously decided, due to consumer pressure, to remove triclosan from hand soaps years ahead of the FDA decision. Researchers collected and tested the urine of 389 mothers and their children –three times during pregnancy, and then took between 1-6 samples from children between the ages of 1 and 8 years old. The researchers found triclosan in over 70% of samples taken. In the group of 8 year olds, they report that levels were 66% higher in the children that used hand soap. For those that wash their hands over five times a day, the levels increase more than four times in comparison to children who wash their hands once or less per day. For toothpaste, researchers find that children who had […]

(Beyond Pesticides, May 19, 2017) In spite of a growing body of evidence implicating glyphosate in a wide range of human illnesses and environmental impacts, the European Union (EU) plans to propose a 10-year extension for the approval of glyphosate use. Previously, the European Commission (the Commission), which is in charge of the approval, was forced to issue a limited license extension for the chemical because member states could not reach a consensus. The Commission was holding out for further information on carcinogenicity, which was assessed by the European Chemicals Agency (ECHA), and whose report was issued in March 2017. According to ECHA’s assessment, glyphosate is not carcinogenic. Glyphosate is the active ingredient in Monsanto’s Roundup brand of weed-killers, and research by the World Health Organization’s International Agency for Research on Cancer (IARC) has found that it is a probable human carcinogen. Since IARC’s findings were released, Monsanto has made several efforts to discredit the research of this well respected, international body, including attempting to influence government agencies. According to a Bloomberg BNA article, “The commission will discuss with EU member nations the prospect of a 10-year reauthorization, said Anca Paduraru, spokeswoman for the commission.” Once the Commission proposes the […]

(Beyond Pesticides, May 12, 2017) Researchers from the University of California San Diego, School of Medicine, in collaboration with scientists from Ecuador and Minnesota, have found that exposure to heavy pesticide use during peak periods can impact neurobehavioral performance in children. The study focused on exposure to organophosphate pesticides, which have been associated with a broad range of diseases in both children and adults. The study, published in NeuroToxicology, involved 308 non-worker Ecuadorian children between the ages of 4 and 9. Neurobehavioral performance for each child was tested once between 63 and 100 days after the Mother’s Day flower harvest, which is a period of high pesticide use in Ecuador. The researchers found that children examined sooner after Mother’s Day had lower scores than children who were tested later. “Children examined sooner after the flower harvest displayed lower performance on most measures, such as attention, self-control, visuospatial processing (the ability to perceive and interact with our visual world) and sensorimotor (eye-hand coordination) compared to children examined later in a time of lower flower production and pesticide use,” said Jose R. Suarez-Lopez, MD, PhD, and lead author of the study, to ScienceBlog. Dr. Suarez-Lopez continued, “This discovery is novel because it […]

(Beyond Pesticides, April 11, 2017) New data presented last week at a children’s health conference show that glyphosate, the active ingredient in the popular Roundup weed killer, is detected in pregnant women and could lead to adverse pregnancy outcomes, including shorter gestation times and lower birth weights. The researchers here are calling for more biomonitoring of the presence of glyphosate in the public, in spite of industry and government efforts to undermine the science surrounding the human health impacts of the herbicide. Researchers tested and tracked 69 expectant mothers and found that the presence of glyphosate levels in their bodily fluids correlated with unfavorable birth outcomes. The research is still in preliminary stages and is a project of the Children’s Environmental Health Network (CEHN), which is studying the reproductive and children’s health impacts of rising herbicide use in the Midwest. The preliminary results were presented at CEHN’s conference last Thursday in Washington DC. Learn more about the project here. This is a huge issue,” said Paul Winchester, M.D., member of the research team involved with this study, medical director of the neonatal intensive care unit at the Franciscan St. Francis Health system and professor of clinical pediatrics at Riley Hospital for […]

(Beyond Pesticides, April 4, 2017) Exposure to commonly used pyrethroid insecticides results in the early onset of puberty in boys, according to a study presented at the 99th meeting of the Endocrine Society in Orlando, Florida this week. Pyrethroids, which exhibit endocrine disrupting properties, have the ability to interfere with the proper regulation of the human body’s hormonal system. This research is the first to investigate not only the association between pyrethroids and accelerated puberty, but also the causal mechanisms involved in the physiological changes taking place within the human body. For the study, Jing Liu, PhD, and colleagues from Zhejuang University in China, analyzed the urine in 463 Chinese boys aged 9 to 16 for the presence of metabolites from the pyrethroid insecticide cypermethrin. Results show that a 10% increase in the metabolite 3-PBA is associated with a roughly 4% increase in luteinizing and follicle-stimulating hormones, which facilitate puberty and sperm production. The author’s note that, “Boys with increased urinary levels of 3-PBA have a significantly increased risk of earlier pubertal onset, in which the odds of being in an advanced pubertal stage are increase by 73% to 110%.” The study, acknowledging the limitation in determining causality, further investigates the […]

(Beyond Pesticides, March 31, 2017) On Wednesday, Scott Pruitt, the new head of the Environmental Protection Agency (EPA), rejected the conclusions of EPA scientists, and independent scientific literature, and reversed a tentative decision from 2015 to revoke food residue tolerances of chlorpyrifos due to the chemical’s neurotoxic impacts. This would have effectively banned chlorpyrifos from agriculture. This decision stemmed from a petition and lawsuit filed by the Natural Resources Defense Council (NRDC) and Pesticide Action Network North America (PANNA)  ten years ago, calling for EPA to revoke all chlorpyrifos tolerances and cancel all registrations. A Federal Appeals court mandated that EPA take final action by March 31, 2017. Mr. Pruitt’s decision leaves the door open for continued neurotoxic dangers for humans, especially children, who have been shown to be especially vulnerable to chlorpyrifos. Chlorpyrifos is part of the organophosphate (OPs) class of pesticides, which were used in World War II as nerve agents. As potent neurotoxicants, organophosphates are extremely harmful to the nervous system, given that they are cholinesterase inhibitors and bind irreversibly to the active site of an enzyme essential for normal nerve impulse transmission. The scientific evidence of neurotoxic dangers associated with chlorpyrifos exposure is extensive and consistent. Epidemiological data also […]

(Beyond Pesticides, March 21, 2017) Last week, the California Department of Pesticide Regulation (CDPR) released revised rules regarding notification of pesticide applications near schools, weakening standards despite opposition from community and public health groups. The new rules rescind a requirement that schools be granted 48 hours prior notification for a planned application of agricultural pesticides within ¼ mile of a school site. CDPR has re-opened public comments on the new rules, and concerned residents have until April 4 to submit a short statement urging increased protections to the Department at [email protected]. Public health, farmworker, and community groups had urged CDPR to strengthen, not weaken common-sense protections for children’s health. As the rules currently stand, applications of toxic, drift-prone pesticides will only be restricted within ¼ mile of a school site, and only during the hours of 6am to 6pm on weekdays. The original proposal required 48 hour prior notification for other agricultural pesticide applications occurring within ¼ mile of school sites during these times. However, CDPR’s revised rules now only require 48 hour notification if the pesticides applied are not on a list provided to school officials at the beginning of the year. Applicators will still be required to submit annual reports […]

(Beyond Pesticides, March 7, 2017) Another study, published by a team of French scientists in the journal Occupational and Environmental Medicine, links childhood behavioral problems to pyrethroid insecticide exposure. Synthetic pyrethroids are a class of insecticides that have increased in use over the past decade due to assumptions that they pose fewer risks to human health than older pesticide chemistries, such as organophosphates. However, this latest study is part of a growing body of research showing that pyrethroids share similar neurocognitive health concerns as these older pesticides. .   In this research, scientists investigate the interplay between pyrethroid exposure and behavioral problems through a longitudinal cohort study, which tracks levels of pyrethroid metabolites, or breakdown products, in the urine of mothers beginning between six and 19 gestational weeks and then in their children up through six years of age. Children’s behavior is measured through a screening questionnaire known as the Strengths and Difficulties Questionnaire (SDQ). SDQ measures how social a child is (altruism), whether the child has difficulty sharing problems or asking for help (internalizing disorders), as well as how defiant or disruptive a child is (externalizing disorders). The study controlled for a number of confounding factors, such as weight, education, location (rural or […]

(Beyond Pesticides, December 23, 2016) The Environmental Agency (EPA) has finalized a proposal to ban 72 inert (or secret hazardous) ingredients from use in pesticide formulations following a long fight with environmentalists who, in 2006, asked that pesticide product labels disclose any of 371 inert ingredients that could be in products. While this finalization is a step in the right direction, ultimately the move is viewed by advocates as inadequate. The original petition, submitted by Northwest Coalition for Alternatives to Pesticides, along with Beyond Pesticides, Physicians for Social Responsibility, and nearly 20 other organizations, called on the agency to require disclosure of inerts. To put the announcement in perspective, EPA is acting on 72 inert ingredients that are no longer being used, such as turpentine oil, and nitrous oxide. An inert ingredient is defined as any ingredient that is “not active,” or specifically targeted to kill a pest. According to a 2000 report produced by the New York State Attorney General, The Secret Ingredients in Pesticides: Reducing the Risk, 72 percent of pesticide products available to consumers contain over 95 percent inert ingredients and fewer than 10 percent of pesticide products list any inert ingredients on their labels. The report also found […]