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Daily News Blog

Archive for the 'Amyotrophic Lateral Sclerosis (ALS)' Category


30
Sep

Neonicotinoid Insecticides Trigger Neurodegeneration and Can Blind Insects at Low Doses

(Beyond Pesticides, September 30, 2020) Low doses of neonicotinoid (neonic) insecticides are known to disrupt insect learning and behavior, but new science is providing a better understanding of how these effects manifest at a cellular level. Published in the Proceedings of the National Academy of Sciences, this study finds that the neonic imidacloprid binds to brain receptors, triggering oxidative stress, reducing energy levels, and causing neurodegeneration. “Although many studies have shown that low doses of insecticides can affect insect behavior, they have not uncovered whether insecticides trigger changes at the cellular and molecular levels,” said lead author Felipe Martelli, PhD, of Monash University in Melbourne, Australia. “The goal of this work was to have a better understanding of the effects of low doses of the common insecticide imidacloprid at the cellular, physiological and behavioral levels.” Researchers used the fruit fly Drosophilia melanogaster, a common experimental organism, as it contains a number of nicotinic acetylchloline receptors, the primary site of action for imidaclorpid. The neonic binds to these receptors, which regulate a number of physiological processes, such muscle contraction. Binding closes these channels, leading to the range of harm researchers observed through their study. Larval fuit flies were exposed to imidacloprid […]

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04
Sep

Pesticide Drift from Greenhouses Adversely Affects Children Living Nearby

(Beyond Pesticides, September 4, 2020) When pesticide drift is investigated, it is most often drift from agricultural fields that is examined. A new study shows that off-target drift of pesticides from greenhouses is also a reality. This research deduced such drift of organophosphate and carbamate pesticides from crop applications done in Ecuadoran floriculture greenhouses by evaluating the acetylcholinesterase enzyme (AChE) activity, necessary to the transmission of nerve impulses, in children residing nearby. The team finds that children living in homes near greenhouses in which these insecticides (widely recognized as cholinesterase inhibitors) are used exhibit reduced activity of this enzyme and abnormal functioning of the nervous system. Beyond Pesticides has monitored the pesticide drift issue intensively, and has long advocated for far better protections for farmworkers. This new information connects those issues, and expands the “drift” concerns to include risks to people working in greenhouses, and to those, especially children, who happen to live near greenhouse-type structures in which these toxic chemicals are used. The study evaluates data during three separate periods (2008, April 2016, and July–October 2016) on 623 children, aged 4–17, living in floricultural communities in Ecuador. The research is part of the study of the Secondary Exposure to Pesticides […]

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28
Aug

EPA Threatens Public Health, Waiving Safety Review of Disinfectants To Be Used by American Airlines and Health Care Facilities; Need Questioned while More Uses Expected

(Beyond Pesticides, August 28, 2020) The Environmental Protection Agency (EPA) has granted “emergency” permission to the State of Texas to allow the use of SurfaceWiseÂŽ2, an unregistered pesticide, as an anti-viral surface coating. The manufacturer, Allied Bioscience, says the compound can kill coronaviruses (including SARS-CoV-2) starting at two hours post application and for up to seven days, but it is not included on EPA’s List N, of disinfectants effective against SARS-CoV-2. EPA has permitted this use via the authority of Section 18 of the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), which allows for “emergency” use of non-registered pesticides, typically to deal with extreme threats to agricultural activities. It is rarely used for public health emergencies. Beyond Pesticides recognizes the need for protection from transmission of the novel coronavirus, and maintains that it ought to and can be done without exposing people to toxic synthetic pesticides that have not undergone evaluation for safety. See Beyond Pesticides’ guidance on effective and safe precautions against the novel coronavirus. The Texas Department of Agriculture secured the EPA exemption, making the state the first to do so; Allied BioScience is pursuing this emergency waiver across all 50 states. The exemption grants American Airlines and two health […]

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03
Aug

Tell Congress to Require EPA to Stop Ignoring People of Color in Setting Safety Standards—Agency Ignores People at Elevated Risk to Deadly Combination of Pesticides and Covid-19 Exposure

(Beyond Pesticides, August 3, 2020) The effects of pesticide use are important, yet ignored, factors affecting people of color (POC) who face elevated risk from Covid-19 as essential workers, as family members of those workers, and because of the additional or cumulative risk that pesticides pose. As a part of this deadly combination, exposure to pesticides occurs at work, in community parks, schools and playing fields, and through food residues. EPA is ignoring the real hazards resulting from a combination of exposures that is reflected in the statistics that have emerged—with farmworkers suffering a rate of coronavirus five times higher and landscapers three times higher than community rates. Why is this the case? Because pesticide exposure weakens the respiratory, immune, and nervous system and makes those exposed more susceptible to the coronavirus.  EPA has the power to immediately, on an emergency basis, adjust allowable pesticide use and exposure, recognizing that we have alternative practices and products to meet food production and landscaping needs. Tell Congress to require EPA to examine the contribution of pesticide exposure to Covid-19 and protect those at greatest risk, people of color. Farmworkers and landscapers have been deemed essential employees during the coronavirus outbreak, but without mandated […]

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14
Jul

Mexico Announces Glyphosate-Roundup Phaseout

(Beyond Pesticides, July 14, 2020) The Mexican government announced late last month that it plans to phase out the importation and use of glyphosate in the country over the next four years. The announcement means that Mexico will join other countries, such as Luxembourg, Vietnam, Germany in prohibiting the chemical and the toxic consumer products, like Roundup, that contain it as an ingredient. International watchdogs are keeping an eye on reactions from the United States, which in recent years has worked to intervene in other countries’ decision-making over toxic pesticides. The government’s announcement cites the Precautionary Principle as part of its decision-making. According to the Wingspread Statement on the Precautionary Principle, “Where an activity raises threats of harm to the environment or human health, precautionary measures should be taken even if some cause and effect relationships are not fully established scientifically.” In the case of glyphosate, there is strong evidence, per a 2015 review by the International Agency for Research on Cancer (IARC), that glyphosate is carcinogenic. Since 2015, several more publications have added weight to glyphosate’s link to cancer. A February 2018 meta-analysis finds “a compelling link between exposures to GBH [glyphosate-based herbicides] and increased risk of NHL [non-Hodgkin […]

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07
Jul

Study Matches Parkinson’s Disease Risk to Zip Code, Proximity to Pesticide Use

(Beyond Pesticides, July 7, 2020) One’s zip code plays an important role in the likelihood of developing Parkinson’s disease (PD), according to data published by Louisiana State University researchers in the International Journal of Environmental Research and Public Health. With genetics and exposure to agricultural pesticide use identified as the main factors affecting PD, proximity to certain cropland and its effluent had a major impact on disease risk. As with most environmentally related diseases, this study highlights the disproportionate risk and environmental racism low income, indigenous and people of color communities endure. Researchers received access to over 23,000 PD diagnoses in Louisiana between 1999 and 2012, and mapped these data by zip code. Risk was determined calculating the number of diagnoses per 10,000 people in a given zip code, based on census data. To flesh out the role agriculture was playing in PD diagnoses, additional data derived from water quality samples taken by the Louisiana Department of Health and Hospitals, and the U.S. Geological Survey pesticide use estimates were compared against reported disease incidence. Results show that certain zip codes faced significantly higher incidence of PD than others in the state. Further, “The PD high-risk areas match closely the arbor-pastoral […]

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28
May

Occupational Exposure to Pesticides, and Other Environmental Chemicals Increase Risk of Developing ALS

(Beyond Pesticides, May 28, 2020) Exposure to agricultural and industrial pesticides, solvents (thinners), electromagnetic fields, and heavy metals predispose humans to amyotrophic lateral sclerosis (ALS), according to an Italian research study, “Environmental and Occupational Risk Factors of Amyotrophic Lateral Sclerosis: A Population-Based Case-Control Study,” published in the International Journal of Environmental Research and Public Health. Although research supports ALS’s genetic etiology, epidemiologic research associating ALS risks and to environmental, or work-related risk factors (i.e., pesticide use, pollutant exposure, heavy metal exposure, etc.) has been inconsistent and non-definitive. This research demonstrates the importance of assessing aggregate health risks associated with occupational pesticide exposure, especially when determining potential exposure routes in specific occupational sectors. In the study, researchers note, “In particular, having an occupation in the agricultural sector, especially with a long duration of the working activity as well as occupational exposure to some chemicals…might increase ALS risk.” While scientists extensively study the epidemiology of amyotrophic lateral sclerosis (ALS)—a rare, yet fatal neurodegenerative disease—occupational and environmental hazards inducing random (sporadic) or hereditary ALS diagnoses remain vague. With researchers predicting a global ALS incidence increase of 69% by 2040, identifying ALS’s causal factors are important to future research. In this research, Italian researchers conducted a case-control, […]

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15
May

Glyphosate in Roundup Linked to Parkinson’s Disease

(Beyond Pesticides, May 15, 2020) New research out of Japan’s Chiba University suggests that exposure to glyphosate, the active ingredient in the most commonly used pesticide worldwide (Roundup), may be a risk factor in the development of Parkinson’s Disease. The ubiquity of glyphosate use in agriculture — which leaves residues of the toxic chemical in food — may mean that exposures to it represent a significant risk factor for the disease. Glyphosate is already implicated or proved in the development of numerous health anomalies, including cancer. Beyond Pesticides recognizes that pesticides play a variety of roles in causing or exacerbating negative health outcomes, including Parkinson’s Disease (PD). Transitioning pest management — in agriculture, land management, and household and personal care contexts — to nontoxic and organic approaches is the critical step away from bathing humans and the Earth in harmful chemicals. The researchers in this subject study, out of the Chiba University Center for Forensic Mental Health’s Division of Clinical Neuroscience, sought to investigate whether exposures to glyphosate could impact dopaminergic neurotoxicity in the brains of mice. They found that exposures to glyphosate in adult mice intensified a type of neurotoxicity associated with PD. [The abstract for the research paper, titled […]

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07
May

Court Requires EPA to Respond to Petition to Ban Toxic Pesticide in Pet Products

(Beyond Pesticides, May 7, 2020) On April 22, 2020, the Ninth Circuit U.S. Court of Appeals granted the U.S. Environmental Protection Agency (EPA) 90 days to respond to Natural Resources Defense Council’s (NRDC) petition requesting cancellation of tetrachlorvinphos (TCVP), a toxic organophosphate pesticide in pet products. The order followed the Ninth Circuit’s decision to grant NRDC’s petition for a writ of mandamus (a court’s order requiring a lower court or public authority to perform its statutory duty) as EPA withheld action to fulfill NRDC’s judicial review of TCVP, for over a decade. A favorable ruling on NRDC’s mandamus petition can influence other petitioners that hope to coerce agency action, especially when public health is at risk. The court states, “Repeatedly, the EPA has kicked the can down the road and betrayed its prior assurances of timely action, even as it has acknowledged that the pesticide poses widespread, serious risks to the neurodevelopmental health of children.” NRDC petitioned EPA to cancel TCVP pesticide registration under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) in April 2009, after studies indicated humans absorb TCVP through contact with pesticide-treated pet products. EPA failed to respond to the initial petition after five years, and NRDC filed a 2014 mandamus requiring […]

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12
Feb

Major Manufacturer of Chlorpyrifos Drops Out of Market, But EPA Continues to Allow Use

(Beyond Pesticides, February 12, 2020) Corteva, a company spun-off from DowDupont, will stop producing chlorpyrifos by the end of this year as a result of declining sales. Despite the move being in the interest of public health, the company is earning little praise from health advocates for what amounts to simply a shrewd financial decision. As news articles on the announcement have noted, Corteva will continue to support Environmental Protection Agency (EPA) registration of chlorpyrifos, which allows generic manufacturers to continue to sell this brain-damaging chemical. “Other people are going to continue to profit from harming children,” said Marisa Ordonia, an attorney with the group EarthJustice to Canada’s National Observer. “It is big that such a major player is saying no, we’re not going to do this any more. It’s a great signal that people don’t want brain-damaging pesticides on their food. But we’re going to continue to keep fighting to make sure children and farmworkers are protected.” At odds is the difference between halting production of chlorpyrifos and cancelling its EPA registration. While Corteva has the ability to voluntarily stop producing its own product, EPA registration permits other generic manufacturers to continue to producing the product. And, over the […]

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17
Oct

Despite Damning Scientific Evidence, EPA Dismisses Link Between Parkinson’s and Exposure to the Herbicide Paraquat

(Beyond Pesticides, October 17, 2019) The U.S. Environmental Protection Agency (EPA) is downplaying the connection between exposure to the herbicide paraquat and the development of Parkinson’s disease, per registration review documents released by the agency this week. Although unsurprising given the current administration’s track record of defending some of the most heinous chemicals still on the market, the review nonetheless marks a low point for scientific integrity within EPA’s Office of Pesticide Programs, according to advocates. Health and environmental advocates have already discounted EPA’s industry-biased review, and are instead pushing hard for Congressional action – namely HR 3817, the Protect Against Paraquat Act, introduced by Congresswoman Nydia Velazquez (D-NY). Under federal law, pesticides are required to undergo reevaluation every 15 years. Paraquat is a potent restricted use herbicide, not available to be applied by residential users, but permitted for use on multiple agriculture crops. Over the last decade, independent peer-reviewed scientific studies have repeatedly found strong associations between paraquat to the development of Parkinson’s disease. Many of these studies have been covered in Beyond Pesticides’ Daily News or are recorded in the Pesticide-Induced Diseases Database. In response to this growing body of literature, EPA conducted an epidemiological evaluation of published […]

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25
Sep

Mysterious “Havana syndrome” Linked to Neurotoxic Pesticide Exposure

(Beyond Pesticides, September 24, 2019) In 2016, Canadians and Americans residing in Havana reported symptoms of headaches, dizziness, nausea. They described hearing strange buzzing and high-pitched sounds – some woke in the middle of the night fumbling for alarm clocks that were not going off. Media used the term “Havana syndrome” to describe the illness. Diplomats, scared by symptoms that seemed to only hit them in their hotel rooms or at home, speculated that a sonic weapon was being used against them. The Trump administration accused Cuban leaders of misconduct and removed all but essential employees. Later, some suspected that the diplomats could have experienced “mass hysteria.” A new Canadian study provides a more likely explanation to this mysterious illness that impacted diplomats in Havana: neurotoxic pesticide exposure. Researchers conducted testing on 14 individuals who had resided in Havana and a control group of 12 that had never lived there. Some of the experimental group had been recently exposed while others, tested 19 months after their return, were classified as “remotely exposed.” Tests included brain imaging and self-reported symptom questionnaires. They analyzed blood samples for routine biochemistry, kidney, liver, and metabolic functions. Individuals that showed symptoms of brain injury went […]

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21
Aug

Children’s IQ Negatively Impacted by Maternal Fluoride Exposure, According to Study

(Beyond Pesticides, August 21, 2019) A birth cohort study in Canada found elevated levels of fluoride exposure during pregnancy are associated with lower IQ scores in 3 to 4-year-old children. This new research, published in the journal JAMA Pediatrics, builds on previous analyses that suggest high fluoride exposure is related to adverse effects to children’s neurodevelopment. Researchers recommend that pregnant mothers should reduce fluoride intake during pregnancy. Noting the controversy of the study, JAMA Pediatrics editor Dr. Dimitri Christakis said it was subjected to “additional scrutiny for its methods and the presentation of its findings.” The Maternal-Infant Research on Environmental Chemicals (MIREC) program recruited pregnant mothers to participate in the study from 2008-2011. A total of 601 mother-child pairs from 6 major cities participated; 41% of them lived in cities with fluoridated municipal water. Exposure was measured through urine samples as well as self-reported maternal daily intake. Children were between ages 3 and 4 when tested for IQ. A 1mg/L increase in maternal urinary fluoride is associated with a 3.7-point decrease in IQ. These findings echo a previous study in Mexico that found a 6-point lower IQ score in school-age children associated with a 1mg/L in maternal urinary fluoride. Women who […]

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23
Jul

Protect Workers and the Public from Parkinson’s Disease: Support H.R. 3817

(Beyond Pesticides, July 23, 2019) Last week, U.S. Representative Nydia M. Velazquez introduced legislation to cancel all uses of the pesticide paraquat, which is acutely toxic and strongly linked to Parkinson’s disease. The move is supported by the Unified Parkinson’s Advocacy Council – a group led by The Michael J. Fox Foundation for Parkinson’s Research – as well as other health and environmental groups such as Beyond Pesticides. Paraquat, which is a dangerous, fast-acting nonselective herbicide that kills by burning living tissues, is also unnecessary. Organic agriculture provides an alternative that does not depend on toxic chemicals like paraquat. Tell your U.S. Representative to support H.R. 3817 to cancel the use of paraquat. According to the EPA, “one small sip [of paraquat] can be fatal, and there is no antidote.” Advocates are pushing for its elimination from the American agriculture system for many reasons, including acute toxicity and organ failure by inhalation, oral intake and dermal absorption; chronic toxicity affecting the eyes, lungs, liver, kidneys and endocrine system; and a higher incidence of various cancers after exposure. The EPA characterizes paraquat as “extremely biologically active and toxic to plants and animals.” The agency has previously determined that exposure to this herbicide […]

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22
Jul

EPA Allows Continued Use of Neurotoxic Insecticide Chlorpyrifos on American Food

(Beyond Pesticides, July 22, 2019) The U.S. Environmental Protection Agency (EPA) will permit the continued use of a known neurotoxic insecticide on the food the Americans eat, the agency announced yesterday in response to a lawsuit filed by public health groups. Health advocates say the move to continue chlorpyrifos use is the latest example of the agency working to protect the profits of industry over the health of Americans. “By allowing chlorpyrifos to stay in our fruits and vegetables, Trump’s EPA is breaking the law and neglecting the overwhelming scientific evidence that this pesticide harms children’s brains,” said Patti Goldman, an attorney for Earthjustice. “It is a tragedy that this administration sides with corporations instead of children’s health.” Under a lawsuit filed in the 9th Circuit US Court of Appeals, EPA had 90 days to provide a justification for why the pesticide should remain on the market. EPA denied the petition yesterday, and rather than providing positive justification for continued use of the chemical, attacked the sound science claimants urged the agency to consider as “not…valid, complete, and reliable.” In the absence of EPA action, several states are leading in the protection of their residents by rejecting the agency’s determination regarding […]

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04
Jun

Starbucks Sued for Illegally Using Carcinogenic Pesticide Near Food and Beverages

(Beyond Pesticides, June 4, 2019) A class-action lawsuit is accusing Starbucks stores in New York of misusing a highly toxic, carcinogenic pesticide near food, putting the health of customers and employees at risk.  “Stores throughout Manhattan have for many years been permeated with a toxic pesticide called Dichlorvos [DDVP], which is highly poisonous and completely unfit for use in proximity to food, beverages and people,” the suit reads. According to the lawsuit, Hot Shot brand No Pest Strips were placed in food areas in violation of labels that prohibit the pesticide’s use in “the food/feed areas of food/feed processing or food/feed manufacturing or food/feed service establishments.” A pest control operator found the illegally placed products on a number of separate occasions, hidden under bagels or in pastry display cases, during a five year period from 2013 to 2018. This was not at only one location, but appeared to be a common occurrence at nearly every one of the 100+ stores serviced by the pest control operator. The case brings to light a number of issues with the use of synthetic pesticides. The unsanitary conditions permitted to persist within Starbucks stores, per the pictures provided in the suit (see page 14), […]

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20
May

Take Action: As EPA Fails to Act, States Take Up the Responsibility to Protect Health and the Environment

(Beyond Pesticides, May 20, 2019) The bans of chlorpyrifos in three important agricultural states show the support for a ban of the chemical nationwide. Hawai’i banned chlorpyrifos a year ago with a unanimous vote of the legislature. New York and California banned it this month. States have been pursuing bans since the Environmental Protection Agency rescinded its proposed ban in 2017. Tell Your Governor to Ban Neurotoxic Pesticides and Support Organic; Send Thanks to Your Governor in Hawai’i, New York, and California Like other organophosphate pesticides, chlorpyrifos has been linked to damaging and often irreversible health outcomes in workers, pregnant women, and children. A widely used pesticide, agriculture companies annually spray six million pounds on crops like citrus, apples, and cherries.  In the same family as Sarin gas, the substance was initially developed prior to World War II as a chemical weapon. It can overstimulate the nervous system to cause nausea, dizziness, and confusion. With very high exposures (accidents or spills), it can cause respiratory paralysis and even death. When applying the chemical to fields, workers must wear protective garments such as respirators. Workers are then blocked from entering the fields from 24 hours up to 5 days after application due to the chemical exposure risk. A group of leading toxics […]

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24
Apr

Federal Court Orders EPA to Justify Use of Chlorpyrifos within 90 Days

(Beyond Pesticides, April 24, 2019) On April 19, the U.S. Court of Appeals for the 9th Circuit ordered the U.S. Environmental Protection Agency (EPA) to provide a justification for why chlorpyrifos, a neurotoxic insecticide commonly used in agriculture, should remain in the U.S. market. The EPA has 90 days to comply. Chlorpyrifos has been linked to damaging and often irreversible health outcomes in workers, pregnant women, and children. Low levels of exposure early in life can lead to increased risk of learning disabilities including lowered IQ, developmental delay, and attention deficit/hyperactivity disorder (ADHD). Farmworkers and their children are disproportionately affected by the use of this chemical because they are exposed at work, home, and even at school. “While we are moving forward, the tragedy is that children are being exposed to chlorpyrifos, a pesticide science has long shown is unsafe,” said Earthjustice Attorney Patti Goldman in a statement. “We hope Trump’s EPA finally decides to protect the future of countless children and the health of millions of farmworkers.” The battle against chlorpyrifos has been long and drawn out, though there has been significant movement in the last few months. Beyond Pesticides has put together a brief timeline of events: A […]

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05
Feb

EPA-Registered Herbicide Found to Trigger Inflammation Linked to Onset of Multiple Sclerosis

(Beyond Pesticides, February 5, 2019) Linuron, an herbicide registered for use by the U.S. Environmental Protection Agency (EPA), yet recently banned in Europe due to health concerns, appears to trigger inflammatory signals that have been linked to the onset of Multiple Sclerosis (MS). This new evidence, published in the journal Cell by researchers at Brigham and Women’s Hospital in Boston, MA, indicates that exposure to chemicals and pesticides in the environment may be a risk factor in the development of neurodegenerative diseases. “We created a platform to systematically investigate the understudied effects of environmental exposures,” said study coauthor Francisco Quintana, PhD. “The goal of our work is to return results that can guide future epidemiological studies and identify actionable targets.” Researchers began their investigation with 976 chemicals identified by EPA’s ToxCast program, an inventory of compounds that have undergone screening for a battery of laboratory tests. Within that inventory, 75 chemicals, including linuron, were found to interfere with the signaling pathways linked to MS. To confirm the adverse impacts, scientists used the embryos of zebrafish, animals often used as models in laboratory research. The zebrafish embryos were altered to contain low levels of myelin, a protein that protects nerve cells, as […]

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22
Jan

Help Get Neurotoxic Pesticide, Chlorpyrifos, Out of Agriculture

(Beyond Pesticides, January 22, 2019) Earlier this month, U.S. Representative Nydia VelĂĄsquez (D-NY) introduced The Ban Toxic Pesticides Act, H.R.230 which bans the insecticide chlorpyrifos from commerce. Chlorpyrifos is a toxic chemical that has been linked to damaging and often irreversible health outcomes in workers, pregnant women, and children. As a result of a revised human health risk assessment, the Environmental Protection Agency (EPA) developed a regulation to ban chlorpyrifos in 2016. Under the Trump Administration, the EPA has taken steps to reverse the regulation. “It’s unconscionable for EPA to turn a blind eye as children and workers are exposed to this poison,” VelĂĄzquez said.  “If the EPA won’t do its job when it comes to chlorpyrifos, then Congress needs to act – and do so quickly.” Ask your U.S. Representative to Co-Sponsor H.R. 230 to Stop the Use of the Toxic Insecticide Chlorpyrifos, which Is Damaging Children’s Brains.  Chlorypyrifos is a widely used pesticide. Agriculture companies annually spray 6 million pounds of the substance on crops like citrus, apples, and cherries.  In the same family as Sarin gas, the substance was initially developed prior to World War II as a chemical weapon. It can overstimulate the nervous system to cause […]

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20
Dec

New Developments in the Link Between Parkinson’s and Pesticides

(Beyond Pesticides, December 20, 2018) Using low doses of the herbicide paraquat and common proteins found in food called lectins, researchers were able to recreate the symptoms of Parkinson’s disease in rats. Results of this study, published in the journal Parkinson’s disease, provide scientists with fresh insights into the development of the disease, and a new model to test potential remedies. Paraquat, a neurotoxic herbicide with a well-established body of literature linking it to Parkinson’s disease, is currently undergoing a registration review by the U.S. Environmental Protection Agency, and groups like the Michael J Fox Foundation are calling for its ban. Researchers based their study on the Braak Staging hypothesis of Parkinson’s, which posits that the disease is brought on by foreign agents entering the body through the gut or nose and making their way to the brain. Rats were exposed to low doses of paraquat combined with lectin every day for a week. After two weeks, the animals’ motor function was tested and compared to an unexposed control group. Rats exposed to lectin and paraquat exhibited Parkinson-like symptoms. Primary author R. Alberto Travagli, PhD, notes, “After observing that these animals did indeed show symptoms of Parkinsonism, we wanted to […]

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04
Dec

California Criticized for Adopting Inadequate Measures to Restrict the Highly Toxic Chlorpyrifos

(Beyond Pesticides, December 4, 2018) In mid-November, the state whose agricultural operations used more than 900,000 pounds of chlorpyrifos in 2016 (down from two million pounds in 2005) moved to establish some temporary restrictions on its use. Regulators at the California Department of Pesticide Regulation (CDPR) issued interim restrictions on the compound while the agency works on a formal regulatory process to list chlorpyrifos as a “toxic air contaminant” and develop permanent restrictions on its use. A neurological toxicant, chlorpyrifos damages the brains of young children: impacts of exposure, even at very low levels, include decreased cognitive function, lowered IQ, attention deficit disorder, and developmental and learning delays. It was slated to be banned for food uses by the U.S. Environmental Protection Agency (EPA) last year, but the decision was reversed by the Trump administration. The interim measures in California include: banning aerial application of chlorpyrifos; ending its use on many crops — except for those determined to be “critical” by virtue of there being few, if any, alternatives (as determined by the University of California Cooperative Extension and listed on DPR’s website); establishing a quarter-mile buffer zone for 24 hours after any application of the pesticide; and requiring a 24/7/365, 150-foot […]

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20
Nov

Evaluation Used to Support Registration of Neurotoxic Chlorpyrifos Found To Be Fundamentally Flawed

(Beyond Pesticides, November 20, 2018) Scientific conclusions used to support the registration of the insecticide chlorpyrifos were flawed and omitted key health impacts, according to a fresh analysis of the original data by a team of independent scientists from northern Europe and the U.S. This re-review not only casts further doubt on the safety of the neurotoxic chlorpyrifos, it highlights a major flaw within federal pesticide regulation that allows pesticide producers to submit their own safety evaluations to the U.S. Environmental Protection Agency without public oversight. “One conclusion we draw is that there is a risk that the results of industry-funded toxicity tests are not reported correctly,” says co-author Axel Mie, PhD. “This makes it difficult for the authorities to evaluate the pesticides in a safe and valid way.” In both the U.S. and European Union, pesticide producers contract with laboratories to perform required safety tests of active ingredients they hope to register for use. While these studies are generally considered ‘confidential business information’ and not available to the public, using Swedish freedom of information laws, researchers were able to obtain two key studies relating to the developmental neurotoxicity of chlorpyrifos. Although not disclosed within the study, it is well […]

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