(Beyond Pesticides, February 1, 2018) Scientists at the European Institute for the Biology of Aging are finding new information about how Parkinson’s disease manifests itself after exposure to the herbicide paraquat, in hopes of finding ways to prevent the progression of the disease. Despite a well-established body of scientific literature linking the paraquat to Parkinson’s, and a ban on the use of the chemical in the European Union that dates back to 2007, its use is still permitted in the U.S. Many health groups, including Beyond Pesticides and organizations like the Michael J Fox Foundation are calling on the U.S. Environmental Protection Agency stop the use of paraquat by denying its upcoming reregistration. Published in the journal Cell Reports, this new research on Parkinson’s investigates the impact of “senescent” cells in the body. Senescent cells are those which, despite being able to divide, stop doing so in response to stress. This is an anti-cancer mechanism, as stress would otherwise cause the cells to multiply unchecked and create malignancies. Researchers suspected that despite the benefit of stopping cancer, senescent cells may be causing other problems in the body. Rather than dying, these cells can cause inflammation in the area around where […]

(Beyond Pesticides, November 9, 2017) Vietnam veterans suffering from certain Agent Orange-related health conditions will continue to wait for compensation. U.S. Department of Veteran Affairs (VA) Secretary David Shulkin announced last week he intends to delay a decision to expand coverage to new illnesses. Despite a robust review by the National Academy of Medicine, which recommended expanding disability compensation for bladder cancer, hyopothyroidism, high blood pressure, and Parkinson’s-like tremors due to past exposure to the toxic herbicide cocktail, the VA decided to take no action. “After thoroughly reviewing the National Academy of Medicine (NAM)’s latest report regarding Veterans and Agent Orange, and associated data and recommendations from the NAM Task Force, I have made a decision to further explore new presumptive conditions for service connection that may ultimately qualify for disability compensation,”  Secretary Shulkin said in a press release last week.  “I appreciate NAM’s work and the commitment and expertise of VA’s NAM Task Force, and look forward to working with the Administration on the next steps in the process.” Given a promise from VA Secretary Shulkin to provide a decision on the new ailments by November 1st, Veterans groups are crying foul, and placing blame on the Trump administration, […]

(Beyond Pesticides, June 13, 2017) Prenatal exposure to commonly used mosquito and agricultural insecticides is associated with decreased motor function in infants, according to a study published in Environment International by a team of Chinese and U.S. researchers. The results of the study should give pause to insecticide-heavy efforts to control mosquitoes as the season ramps up this summer and fall. Frequent spraying as part of efforts to control Zika in Southern Florida last year resulted in large protests and calls for a preventive management approach not dependent on toxic chemicals. For the current study, over 350 pregnant Chinese mothers were tested for the presence of organophosphate pesticides in their umbilical cord blood. Researchers looked at exposure to the insecticides naled, methamidophos, trichlorfon, chlorpyrifos, and phorate. After giving birth, their children’s motor function was tested at both six and nine months of age. Tests included an analysis of the infant’s reflexes, locomotion, grasping, stationary and visual-motor integration abilities. Scores were categorized based on gross, fine, and total motor skills, and standardized quotients were created for each of the categories. Of the over 300 mothers, roughly 240 had detectable levels of one of the insecticides in their samples. Although no differences […]

(Beyond Pesticides, June 8, 2017) On Monday, numerous organizations filed an administrative appeal to the U.S. Environmental Protection Agency (EPA), seeking to reverse Scott Pruitt’s order to continue allowing the toxic organophosphate insecticide chlorpyrifos in agriculture, and revoke all tolerances (allowed food residues) of the chemical. On the same day, Attorneys General (AGs) from seven states announced legal objections to Scott Pruitt’s order, also calling for a reversal of the decision and a revocation of all tolerances. Allowing the continued use of chlorpyrifos runs counter to findings of independent science and EPA’s own scientists, which establish unacceptable risks to humans and the environment. The administrative appeal, filed by Earthjustice on behalf of 12 environmental, labor, and civil rights organizations, resulted from the decision by EPA to allow the use of chlorpyrifos while it studies the safety of the chemical. The seven AGs, in their filing, are charging that EPA wrongfully approved the continued use of chlorpyrifos in agriculture without first gathering and assessing the full safety data, as required by the U.S. Food, Drug, and Cosmetic Act. Many environmental groups spoke out in favor of these filings. “There’s a good reason this dangerous toxin has been banned from indoor use for more […]

(Beyond Pesticides, May 19, 2017) In spite of a growing body of evidence implicating glyphosate in a wide range of human illnesses and environmental impacts, the European Union (EU) plans to propose a 10-year extension for the approval of glyphosate use. Previously, the European Commission (the Commission), which is in charge of the approval, was forced to issue a limited license extension for the chemical because member states could not reach a consensus. The Commission was holding out for further information on carcinogenicity, which was assessed by the European Chemicals Agency (ECHA), and whose report was issued in March 2017. According to ECHA’s assessment, glyphosate is not carcinogenic. Glyphosate is the active ingredient in Monsanto’s Roundup brand of weed-killers, and research by the World Health Organization’s International Agency for Research on Cancer (IARC) has found that it is a probable human carcinogen. Since IARC’s findings were released, Monsanto has made several efforts to discredit the research of this well respected, international body, including attempting to influence government agencies. According to a Bloomberg BNA article, “The commission will discuss with EU member nations the prospect of a 10-year reauthorization, said Anca Paduraru, spokeswoman for the commission.” Once the Commission proposes the […]

(Beyond Pesticides, May 12, 2017) Researchers from the University of California San Diego, School of Medicine, in collaboration with scientists from Ecuador and Minnesota, have found that exposure to heavy pesticide use during peak periods can impact neurobehavioral performance in children. The study focused on exposure to organophosphate pesticides, which have been associated with a broad range of diseases in both children and adults. The study, published in NeuroToxicology, involved 308 non-worker Ecuadorian children between the ages of 4 and 9. Neurobehavioral performance for each child was tested once between 63 and 100 days after the Mother’s Day flower harvest, which is a period of high pesticide use in Ecuador. The researchers found that children examined sooner after Mother’s Day had lower scores than children who were tested later. “Children examined sooner after the flower harvest displayed lower performance on most measures, such as attention, self-control, visuospatial processing (the ability to perceive and interact with our visual world) and sensorimotor (eye-hand coordination) compared to children examined later in a time of lower flower production and pesticide use,” said Jose R. Suarez-Lopez, MD, PhD, and lead author of the study, to ScienceBlog. Dr. Suarez-Lopez continued, “This discovery is novel because it […]

(Beyond Pesticides, March 31, 2017) On Wednesday, Scott Pruitt, the new head of the Environmental Protection Agency (EPA), rejected the conclusions of EPA scientists, and independent scientific literature, and reversed a tentative decision from 2015 to revoke food residue tolerances of chlorpyrifos due to the chemical’s neurotoxic impacts. This would have effectively banned chlorpyrifos from agriculture. This decision stemmed from a petition and lawsuit filed by the Natural Resources Defense Council (NRDC) and Pesticide Action Network North America (PANNA)  ten years ago, calling for EPA to revoke all chlorpyrifos tolerances and cancel all registrations. A Federal Appeals court mandated that EPA take final action by March 31, 2017. Mr. Pruitt’s decision leaves the door open for continued neurotoxic dangers for humans, especially children, who have been shown to be especially vulnerable to chlorpyrifos. Chlorpyrifos is part of the organophosphate (OPs) class of pesticides, which were used in World War II as nerve agents. As potent neurotoxicants, organophosphates are extremely harmful to the nervous system, given that they are cholinesterase inhibitors and bind irreversibly to the active site of an enzyme essential for normal nerve impulse transmission. The scientific evidence of neurotoxic dangers associated with chlorpyrifos exposure is extensive and consistent. Epidemiological data also […]

(Beyond Pesticides, January 9, 2017) After the U.S. Environmental Protection Agency (EPA) released its recent human health risk assessment for the organophosphate insecticide (OP) tetrachlorvinphos (TCVP) on December 21, 2016, the agency announced it was allowing the continued use of the neurotoxic chemical to which children are widely exposed through pets’ flea collars and other flea treatments. According to EPA, ” TCVP is used as a direct animal treatment to livestock (i.e., cattle, horses, poultry and swine) and their premises, in kennels, outdoors as a perimeter treatment, and as a flea treatment [including flea collars] on cats and dogs.” In its announcement on January 4, 2017, EPA states, “We advise consumers to take certain precautions when handling TCVP products in residential areas. These precautions are listed on TCVP product labels, including: not allowing children to play with TCVP pet collar products, keeping TCVP spray and powder products out of reach of children, and washing hands thoroughly with soap and water after handling.” Advocates have raised concerns related to similar decisions on flea collars in the past in which EPA has issued warnings to mitigate risks, despite its inability to ensure children’s safety. Children typically come into close contact with pets and their […]

(Beyond Pesticides, December 21, 2016) A California Department of Pesticide Regulation (DPR) report of all pesticide related illnesses in the state in 2014 identifies 1,685 cases “potentially involving health effects from pesticide exposure,” combining exposures from agricultural and non-agricultural use. Of the 798 cases associated with non-agricultural use, 18% of them (146 cases) involved exposure in children under 18 years old. The exposure rates are alarming, and only strengthen efforts by local activists in counties like Tulare to protect children from pesticide exposure. According to the report, Tulare County has the highest number of reported illnesses related to pesticide exposure at 78, followed by Santa Cruz County with 67. The report, Summary of Results from the California Pesticide Illness Surveillance Program 2014, provides a summary of illnesses identified by the Pesticide Illness Surveillance Program (PISP), a program under DPR. Of the 1,685 cases potentially involving health effects from pesticide exposure reported, DPR epidemiologists determined that 1,073 of those cases were “at least possibly associated” with pesticide exposure, representing a 5% decrease from 2013. However, even though the number of associated cases decreased in 2014, PISP did see a 14% rise in the number of associated episodes, defined as “an event in which a single source […]

(Beyond Pesticides, November 15, 2016) Last week, the U.S. Environmental Protection Agency (EPA) updated its assessment of the toxic organophosphate insecticide chlorpyrifos, keeping in place a decision made last year to revoke food residue tolerances and effectively eliminate its use in agriculture. The agency indicated the change was necessary after a Scientific Advisory Panel convened by the agency suggested additional data to support its decision. This change opens up a 60-day public comment period, but EPA has said that it will make a final decision no later than March 31, 2017. “The revised analyses indicate that expected residues of chlorpyrifos on food crops exceed the safety standard under the Federal Food, Drug, and Cosmetic Act (FFDCA),” EPA noted in its announcement.  “In addition, the majority of estimated drinking water exposures from currently registered uses, including water exposures from non-food uses, continue to exceed safe levels even taking into account more refined drinking water exposures. “ To explain the decision to the public, EPA has put together a FAQ page on its website. EPA’s proposal to revoke chlorpyrifos’ food tolerances stems from a petition and lawsuit filed by the Natural Resources Defense Council and Pesticide Action Network North American nearly ten […]

(Beyond Pesticides, August 10, 2016) In a letter, submitted by the Soil Association, leading bread producers and supermarkets in the United Kingdom (UK) are being urged to cease stocking and selling bread products that  contain traces of the herbicide glyphosate. Glyphosate, the active ingredient in Monsanto’s Roundup, has been classified as a probable human carcinogen by the World Health Organization (WHO) and is linked to numerous other environmental and human health concerns. Glyphosate residues have already been detected in bread, beer, and wine. The Soil Association, a UK organization that campaigns for healthy, humane and sustainable food, farming and land use, is concerned that glyphosate is used on crops immediately before harvest, and subsequently makes its way into food. According to the letter and a spokesperson for the group, “Using glyphosate, and glyphosate-based products, as a pre-harvest treatment is fundamentally wrong, and we are calling for an end to it with our campaign.  Wheat harvest will start in the next few weeks, and we are asking bread companies to act now and put a stop to glyphosate as a pre-harvest desiccant in their supply chains. The EU has just advised glyphosate use as a pre-harvest spray on food crops should […]

(Beyond Pesticides, July 29, 2016)  A study released earlier this week finds lower IQ (intelligence quotient) in children born to mothers who during their pregnancy were living in close proximity to chemical-intensive agricultural lands where organophosphate pesticides were used. This study adds to the body of scientific literature that links prenatal exposure to organophosphate pesticides with lower IQ’s in children. Organophosphate pesticides, a relatively older generation of highly neurotoxic pesticides still widely used on farms in California, have been associated with a  broad range of diseases  in both children and adults.  This  latest study  supports health and environmental advocates’ call to eliminate these toxic pesticides in agriculture and move toward safer, sustainable, and organic management practices. The study, titled  Prenatal Residential Proximity to Agricultural Pesticide Use and IQ in 7-Year-Old Children, looks at 283 women and children from the agricultural Salinas Valley who are enrolled in the long-term Center for the Health of Mothers and Children in Salinas (CHAMACOS) study. Specifically, researchers looked at pregnant women living within one kilometer of agricultural fields where organophosphate pesticides were used. They found that at age 7, the children of those women had declines of approximately two IQ points and three verbal reasoning […]

(Beyond Pesticides July 25, 2016) The Oregon Department of Agriculture (ODA) last week issued 12 notices of statewide detainment and stop sale and removal orders for horticultural pesticide products that contain active ingredients not listed on the label. The orders call for the product manufacturers to immediately cease all sales, offers of sale, or other distribution in Oregon. This is the latest effort by a state with a legalized marijuana market to try to  curb the use of illegal pesticides in cannabis production, a practice that poses potential health threats to consumers, creating a regulatory challenge for state officials in states that have legalized marijuana for medicinal and or recreational purposes. Because the U.S. government classifies cannabis as a narcotic, the U.S. Environmental Protection (EPA) does not register pesticide products for use in its production, leaving consumers exposed to hazardous pesticides through inhalation, ingestion, and dermal absorption without any evaluation of potential health effects. The products in question are commonly used in horticulture and hydroponics, including cannabis production. The 12 notices cover 14 products sold in Oregon that were also identified by the Washington State Department of Agriculture (WSDA) in late June as containing undeclared pesticide active ingredients. In an […]

(Beyond Pesticides, May 16, 2016) Pesticide exposure may increase the risk of amyotrophic lateral sclerosis (ALS), according to a study entitled Association of Environmental Toxins With Amyotrophic Lateral Sclerosis, which was  published in JAMA Neurology. ALS, also known as Lou Gehrig’s disease, is a progressive neurodegenerative disease that affects nerve cells in the brain and spinal cord. The study, which investigated a total of 122 persistent environmental pollutants, including organochlorine pesticides (OCPs), polychlorinated biphenyls (PCBs), and brominated flame retardants (BFRs), found that pesticide exposure increased ALS risk five-fold. Researchers conducting the study  looked at 156 patients with ALS and 128 without the disease. Participants were asked about occupational and residential exposure to environmental toxicants  and blood samples were taken to measure their concentrations. Researchers found that the organochlorine pesticides pentachlorobenzene and cis-chlordane increased ALS risk two-fold and nearly six-fold, respectively. This study does not prove that pesticides cause ALS, but it does build on an association suggested in previous research, study co-author Stephen Goutman, MD, told  HealthDay. Dr. Goutman recommends avoiding pesticides. This is especially wise for anyone with a family history of ALS, he added. The link between pesticide exposure and neurological damage has been studied extensively. In 2008, […]

(Beyond Pesticides, April 1, 2016) A study published yesterday finds  that a certain class of fungicides, the strobilurins, causes genetic changes in the neurons of mice that are similar to genetic changes seen in humans with autism and Alzheimer’s disease. Since their introduction to the market over the past 20  years, these fungicides have been used increasingly on conventionally grown crops like cabbage, spinach, lettuce, kale, tomatoes, apples, pears and grapes. After exposing brain cells from mice to over 300 pesticides and fungicides, researchers found that the strobilurin class of fungicides produces patterns of genetic changes often seen in human neurodegenerative diseases. While the fungicides created autism-like signatures in the way the genes were expressed in mouse neurons, the results do not conclusively show that this class of fungicides causes autism or Alzheimer’s disease. Mark Zylka, Ph.D., lead scientist of the study and associate professor of cell biology and physiology at University of North Carolina, states,  “What this work provides is evidence that these chemicals are bad for neurons. They turn the same genes on or off that you see not only in autism brains, but also in neurodegeneration.” Strobilurins work by disrupting mitochondria, commonly known as the “powerhouse of […]

(Beyond Pesticides, December 11, 2015) Milk contaminated with the long-banned and toxic organochlorine pesticide heptachlor in Hawaii has been found  in the brains of men that were more likely to develop Parkinson’s disease, according to a new study. This study adds to a large body of evidence linking pesticide exposure to Parkinson’s disease. Researchers of the study, titled “Midlife milk consumption and substantia nigra neuron density at death” and published in the journal Neurology, collected milk intake data from 1965 to 1968 for 449 men aged 45-68 years withpostmortem examinations from 1992 to 2004. Neuron density was measured in an area of the brain called substantia nigra (SN). As Parkinson’s develops, cells are destroyed in certain parts of the brain stem, particularly in the SN, a crescent-shaped cell mass. Measurements of brain residues of heptachlor epoxide, a heptachlor metabolite that is persistent and more toxic than its parent chemical, were also taken. “Among those who drank the most milk, residues of heptachlor epoxide were found in 9 of 10 brains as compared to 63.4%…for those who consumed no milk,” the researchers wrote. Neuron density was lowest in subjects who consumed the highest amounts of milk. The researchers looked at milk […]

(Beyond Pesticides, October 27, 2015) Late Friday,  a coalition of public health, conservation and food safety groups filed their opening brief in the ongoing legal challenge to the U.S. Environmental Protection Agency’s (EPA) approval of the herbicide Enlist Duo for use on genetically engineered corn and soybeans. Enlist Duo, a blend of glyphosate and 2,4-D, was approved on October 15 for use on genetically engineered (GE) crops, despite concerns for human and environmental contamination. The challenge was originally brought in November 2014, shortly after the EPA approved the controversial herbicide for 6 Midwest states. Since then, EPA has expanded its approval to a total of 15 states, with more expected. Counsel from the Center for Food Safety (CFS) and Earthjustice are jointly representing Beyond Pesticides, Center for Biological Diversity, CFS, the Environmental Working Group, the National Family Farm Coalition, and Pesticide Action Network North America. “The Enlist Duo approval violated the laws protecting our communities, land, and farms,” said George Kimbrell, Center for Food Safety senior attorney, counsel in the case. “Regulators bowed to the chemical industry, but we are committed to holding them accountable.” The groups argue that in its approval of Enlist Duo, a combination of the herbicides […]

(Beyond Pesticides September 9, 2015) A young Florida boy and his family are reeling after a routine termite treatment resulted in a devastating outcome. Ten-year-old Peyton McCaughey of Palm City, Florida has been in the hospital for weeks following a severe reaction to chemicals used to fumigate his family’s home. According to news reports, the  fumigation was performed by Sunland Pest Control, a subcontractor of Terminix. The Florida Department of Agriculture has since issued a “Stop Work Order” while it  investigates the company in collaboration with the Environmental Protection Agency (EPA) and the state Department of Health. After returning to their home hours after the Terminix subcontractor told them it was safe to enter, the whole family became very ill. While the parents and the 7-year-old daughter recovered, the young boy’s condition continued to worsen. “He was having some uncontrollable muscle movements, couldn’t stand up, couldn’t speak, so they took him to a local walk-in and the doctor quickly recognized it was probably poisoning from a treatment,” said Peyton’s uncle, Ed Gribben. Current reports indicate that the boy has likely suffered brain damage and has lost all muscle control, rendering him unable to stand or speak. He remains in a […]

(Beyond Pesticides, June 23, 2015) After years of denial and obstruction, Air Force and Air Force Reserve veterans now have the chance to receive compensation for their exposure to the highly toxic herbicide Agent Orange on contaminated aircraft used after the Vietnam War. Affected veteran’s health issues stem from their time spent on UC-123 transport planes, which during the war were outfitted with spray equipment in the American military’s attempt to eliminate forest cover for Vietcong fighters. After the war, these aircraft were returned to use in the United States for basic transport operations such as cargo shipping and medical evacuation missions. However, these planes never underwent any form of decontamination or testing before being repurposed. Though the Agent Orange Act of 1991 stipulated medical care and disability coverage for sick veterans who  served in the Vietnam War and were exposed to Agent Orange, those who flew in contaminated post-war planes were deemed ineligible. Prior to this recent announcement from the Department of Veteran’s affairs, government officials asserted that the “dried residues” of Agent Orange were not likely to pose a health threat to aircraft crew. However, a study published by the National Academy of Sciences Institute of Medicine in […]

(Beyond Pesticides, December 23, 2014) The U.S. Department of Agriculture’s (USDA) Agricultural Marketing Service (AMS) has posted a report on its data from the 2013 Pesticide Data Program (PDP) Annual Summary, concluding that although over half of the food tested by the agency for pesticide residues last year showed detectable levels of pesticides, these levels are below the tolerances established by the Environmental Protection Agency (EPA) and do not pose a safety concern. The residues reflect a pesticide use and exposure pattern that raises hazard scenarios that are not fully evaluated by EPA for chemical mixtures, synergistic effects, impacts  on  people and environments  with high risk factors, and certain critical health endpoints, such as endocrine disruption  . Excluding water, of the 9,990 samples analyzed, 23.5 percent had one pesticide detected and 36 percent had more than one pesticide. Residues exceeding tolerances were detected in 0.23 percent (23 samples out of 9,990) of the samples tested. Of these 23 samples, 17 were imported and 6 were domestic. Residues with no established tolerances were found in 3.0 percent of samples, of which 50.2 percent were domestic and 49.2 percent imported. According to USDA, “The Pesticide Data Program provides reliable data through rigorous […]

(Beyond Pesticides, October 15, 2014) A new study published in Environmental Health Perspectives finds a strong relationship between the use of pesticides and depression in farmers. One specific class of pesticide, organochlorines, was associated with a 90% higher chance of being diagnosed with depression. For fumigants, the increased risk was up to 80 percent. This study echoes the conclusion from an earlier French study which also reported that farmers using pesticides face  a greater risk of developing depression. The study, Pesticide Exposure and Depression among Male Private Pesticide Applicators in the Agricultural Health Study, examines possible associations between pesticide exposure and depression among male private pesticide applicators in the Agricultural Health Study (AHS). Over 21,000 applicators who enrolled in the study in 1993—1997 were followed and examined. The applicators were asked about depression when enrolled in the study and then again around 2010. Previous work with this AHS sample found a higher prevalence of depression among male applicators who reported past pesticide poisoning or use of pesticides from several different classes. However, this study examines specific pesticides, and finds that two types of pesticides, fumigants and organochlorine insecticides are positively correlated with depression and cumulative days of use. Those exposed […]

(Beyond Pesticides, January 29, 2014) People with high levels of exposure to the banned insecticide DDT are four times more likely to have Alzheimer’s disease than people with low levels, according to a new study of patients in Georgia and Texas. The research is among the first to report a connection between Alzheimer’s disease, which is the world’s most common neurodegenerative disease, and chemicals in the environment. The traces of the insecticide found in the study’s Alzheimer’s patients are comparable to the amounts found in most Americans today. Although it was banned more than 40 years ago in the U.S., DDT still persists in the environment worldwide and is still used today in developing countries for malaria abatement programs. “Our findings suggest that genetically susceptible individuals with higher levels of DDT exposure may be more at risk,” said Jason Richardson, PhD, a Rutgers University researcher who led the study. The case-control study consisting of existing samples from patients with Alzheimer’s disease and control participants from the Emory University Alzheimer’s Disease Research Center and the University of Texas Southwestern Medical School’s Alzheimer’s Disease Center measured serum levels of DDE in 79 control and 86 Alzheimer’s disease cases. Levels of DDE, a […]

(Beyond Pesticides, December 10, 2013) A former steward for Australian-based Quantas airlines is suing the Australian government claiming that frequent insecticide use in airplane cabins resulted in his Parkinson’s disease diagnosis. Australia is among 49 countries that require pesticide spraying on some or all flights. Pesticide use on flights into the United States is not required, but is permitted under international law. (See here for a breakdown of pesticide use in American-based airlines, and here for information from the U.S. Department of Transportation on pesticide use in aircrafts.) Brett Vollus, former Quantas airline steward, worked for the company for 27 years until this past May when he was diagnosed with Parkinson’s and a malignant brain tumor. “He [my doctor] asked me what I did for living and when I told him he just nodded and said: ‘Another one, I am seeing a lot of you’,” Mr. Vollus said to The Australian. “This is a nightmare that has ruined my life. I am very keen to start a legal action and if it can help others I am happy to lead the way.” This case puts an international spotlight on growing evidence that pesticide use is linked to Parkinson’s disease. Parkinson’s […]