(Beyond Pesticides, June 4, 2021) The release of the most recent U.S. Geological Services (USGS) study of pesticide contamination of rivers on the U.S. mainland finds that degradation of those rivers from pesticide pollution continues unabated. USGS scientists looked at data from 2013 to 2017 (inclusive) from rivers across the country and offered these top-level conclusions: “(1) pesticides persist in environments beyond the site of application and expected period of use, and (2) the potential toxicity of pesticides to aquatic life is pervasive in surface waters.” Beyond Pesticides maintains that ultimately, water quality and aquatic organisms and their ecosystems will be fully protected from pesticides through a wholesale movement to organic land management practices. USGS undertakes periodic assessments of the presence and toxicity of pesticides in the country’s surface waters under the agency’s National Water-Quality Assessment Program. Recent news from these studies has not been good. In September 2020, Beyond Pesticides reported on another, related USGS survey, which found that nearly 90% of U.S. rivers and streams are contaminated with mixtures of at least five or more different pesticides. A March 2021 Beyond Pesticides Daily News article noted that USGS research demonstrated that, of 422 water samples taken from streams across […]

(Beyond Pesticides, June 1, 2021) Farmworkers are at greatest risk from pesticides. EPA’s policies toward farmworkers comprise a blatant example of systemic racism. Although everyone suffers from pesticide poisoning, farmworkers and their families shoulder a disproportionate burden of the hazards.  Agricultural justice demands that we ensure a workplace with fair wages and benefits, no discrimination or coercion, and protection from hazards, such as harmful chemicals, including pesticides. Acknowledging, respecting, and sustaining the workers who plant, cultivate, and harvest our food is central to the basic values and principles that advance sustainable practices. Agricultural justice demands that we ensure a workplace with fair wages and benefits, no discrimination or coercion, and protection from hazards, such as harmful chemicals, including pesticides. Acknowledging, respecting, and sustaining the workers who plant, cultivate, and harvest our food is central to the basic values and principles that advance sustainable practices. Tell EPA to protect farmworkers from pesticides. Worker Protection Standards Are Inadequate to Protect Farmworkers Worker protection standards are set by the U.S. Environmental Protection Agency (EPA) under the Federal Insecticide Fungicide and Rodenticide Act (FIFRA). The original standard was developed after field hearings in which EPA heard from growers, but not farmworkers. With the threat […]

(Beyond Pesticides, May 12, 2021) Earlier this year, a team of scientists solved an ecological mystery that had persisted for decades. Throughout the southeastern United States, bald eagles and other top-level avian predators were experiencing mass deaths from a disease known as vacuolar myelinopathy (VM), a neurological ailment that causes lesions in affected animal’s brains. Scientists identified the source of the exposure as a cyanobacteria growing on an invasive weed, but up until now, did not know how the bacterium caused disease. Now, scientists have determined that the chemical bromine, likely introduced by brominated herbicides in attempts to manage the invasive species, is the trigger for the production of the cyanobacteria’s neurotoxin. In the mid-1990s, over 70 bald eagles died in Arkansas’s DeGray Lake over the course of two years. The event was the largest mass mortality of eagles recorded. Scientists identified the disease as vacuolar myelinopathy, and through the course of several years were able to determine that the disease generally affected birds in the built environment, near artificial bodies of water with high levels of aquatic plant life. Waterfowl and other bird species were found to develop lesions in lakes where there was an ongoing VM outbreak. Evidence […]

(Beyond Pesticides, May 11, 2021) Last week, multinational agrichemical company Bayer Cropscience lost its bid to overturn a 2018 ban on bee-toxic neonicotinoids throughout the European Union. The ruling from the European Court of Justice rejected all grounds on which the company filed its appeal, noting, “It must be held that the arguments put forward by Bayer CropScience cannot, in any event, succeed.” In denying the appeal, the court ruled Bayer responsible for paying its own legal fees, as well as the fees of environmental organizations that intervened to defend the ban. Environmental groups are applauding the ruling, as it reinforces several important aspects of the EU’s pesticide policy that favor greater public health and environmental protections. In an interview with EURACTIV, policy officer Martin Dermine at Pesticide Action Network Europe notes that the decision provides more leeway for pesticide regulators to consider new scientific evidence on pesticide hazards. “More than that,” he told EURACTIV, “the Court confirms the definition of the precautionary principle:  in case of doubts on the toxicity of a pesticide, the European Commission is entitled to ban it.” Pesticide regulators in Europe began restricting neonicotinoids in 2013, when a continent-wide moratorium was put in place based […]

(Beyond Pesticides, May 6, 2021) Nearly half of all breakdown products (transformation products) from four common-use environmental pesticides produce stronger endocrine (hormone) disrupting (ED) effects than the parent compound, according to new research published in Environment International. Over 300 environmental contaminants and their byproducts—from chemicals in plastics to cosmetic/personal care products—are commonly present in water bodies, food commodities, and human blood/urine samples. These toxicants can alter hormone metabolism, producing endocrine-disrupting effects that put the health of animals, humans, and the environment at risk. Many ecological and health risk assessments for pesticides focus on the effects of parent chemical compound products, overlooking the potential impacts of transformation products (TPs). Therefore, studies like these highlight the need to assess the implications of TPs to safeguard human, animal, and environmental health. The researchers note, “Since an increasing number of pesticide TPs have been detected in various environmental media, a more comprehensive understanding of the ecological risk of pesticide TPs is imperative for risk assessments more extensively and regulatory policy-making on pesticide restriction in the future.” Endocrine disruptors are xenobiotics (i.e., chemical substances like toxic pesticides foreign to an organism or ecosystem), including pesticides, bisphenols, phthalates, persistent organic pollutants (POPs), and heavy metals. Past research demonstrates exposure […]

(Beyond Pesticides, April 30, 2021) A bioinformatics tool developed by researchers from the University of Turku in Finland indicates that “54% of species in the core human gut microbiome are sensitive to glyphosate.” This tool may help predict which microbes in the human gut could be negatively affected by exposure to the ubiquitous herbicide. Because damage to the gut biome is linked to a variety of diseases, this information could prove critical in recognition of the role(s) glyphosate may play in the development of human diseases. Published in the Journal of Hazardous Materials, the researchers’ paper states, “The widespread use of glyphosate may have a strong effect on gut microbiomes as well as on human health.” Beyond Pesticides has long reported on the relationship between glyphosate and human health, including potential effects on the human gut microbiome. Used in multiple herbicide formulations, glyphosate has become widely known as the active ingredient in Bayer/Monsanto’s Roundup®, the most-used herbicide worldwide. The pervasiveness of glyphosate-based herbicide (GBH) use in agriculture, and of Roundup in particular, is due largely to their pairing with genetically engineered (GE) seeds for soy, canola, and corn crops. In many regions, these GE seeds — engineered to resist the glyphosate […]

(Beyond Pesticides, April 16, 2021) Recent research, published in Environmental Pollution in late 2020, examines levels and persistence of pesticide pollution in recreational lakes. The study finds: (1) concentrations of the neonicotinoid imidacloprid at levels exceeding ecotoxicity limits for aquatic invertebrates in a recreational lake that receives predominately urban runoff, and (2) that pesticide residues persist in the studied lakes throughout the growing season. Based on their findings, the scientists emphasized the importance of stricter regulation of insecticide compounds, and of better education about their impacts. Beyond Pesticides maintains that neonicotinoid pesticides should be banned for several reasons, not least of which is the extreme damage they cause to pollinators. The goal of the study was to evaluate potential ecosystem exposure to pesticide contamination in Midwestern recreational lakes, as well as the persistence of pesticide residues in those water bodies over the course of the growing season. Study authors hypothesized that watersheds with significant agricultural land uses would have higher concentrations of pesticides compared to largely urban and herbaceous watersheds. This research, out of the University of Nebraska–Lincoln and the University of Kentucky, looked to evaluate the occurrence of neonicotinoid and organothiophosphate insecticides, and some fungicides, in three lakes with differing […]

(Beyond Pesticides, April 8, 2021) Pesticide use threatens aquatic and terrestrial invertebrates and plants more than ever, despite declining chemical use and implementation of genetically engineered (GE) crops in the U.S., according to a University Koblenz-Landau, Germany study. Since the publication of Rachel Carson’s Silent Spring (1962), many environmental agencies have banned the use of pesticides like organochlorines, organophosphates, and carbamates for their devastating toxic—sometimes lethal—effects, particularly on vertebrates, including humans. However, this ban created a pathway for a new generation of pesticides (e.g., neonicotinoids, pyrethroids) to take hold. Although these pesticides are more target-specific, requiring lower chemical concentrations for effectiveness, they have over double the toxic effects on invertebrates, like pollinators.  Invertebrates and plants are vital for ecosystem function, offering various services, from decomposition to supporting the food web. Furthermore, invertebrates and plants can act as indicator species (bioindicators) that scientists can observe for the presence and impact of environmental changes and stressors. Therefore, reductions in invertebrate and plant life have implications for ecosystem health that can put human well-being at risk. Study lead author Ralf Schulz, PH.D., notes, “[This study] challenge[s] the claims of decreasing environmental impact of chemical pesticides in both conventional and GM [genetically modified or genetically engineered (GE)] crops and […]

(Beyond Pesticides, March 2, 2021) Populations of solitary ground nesting bees decline after exposure to neonicotinoid insecticides, according to a study published in Scientific Reports late last month. In addition to ground-nesting bees, neonicotinoids have been shown to harm butterflies, hummingbirds, songbirds, aquatic species and mammals, including humans. As independent science continues to look beyond the effects of these systemic chemicals on honey and bumblebees, advocates maintain that it has become increasingly clear that the high hazards presented by neonicotinoids necessitate their complete elimination. “Farmers need to protect their crops from pests, but they also absolutely need to protect pollinators from the unintended effects of pesticides,” said study coauthor Susan Willis Chan, PhD. “The data on this particular [neonicotinoid] product are so clear that there’s really no question about what has to happen. We have to find something else.” Researchers focused their effort investigating how various systemic pesticides effect the hoary squash bee (Eucera pruinosa), a ground nesting bee found throughout North America that feeds entirely on pollen from cucurbits (including squash, cucumber, pumpkin, gourds, etc). The hoary squash bee provides essential pollinator services for these crops throughout the U.S. and Canada. Neonicotinoids and other systemic insecticides are often applied […]

(Beyond Pesticides, February 25, 2021) A University of Michigan study finds a link between elevated rates of breast cancer incidents and chemical exposure from pesticides among African American women. Breast cancer is the most common cancer among women, causing the second most cancer-related deaths in the United States. However, breast cancer outcomes differ significantly among women of various races/ethnicities, with African American women being 40 percent more likely to die from breast cancer than women of any other race. Furthermore, incidences of triple-negative breast cancer (TNBC)—an aggressive breast cancer subtype lacking remediation—is approximately three-fold higher in non-Hispanic Black women (NHBW) compared to non-Hispanic White women (NHWW). Although past studies suggest genetic and environmental factors interact to produce these differences in breast cancer outcomes, genetic factors only play a minor role while disparities (differences) in external factors (i.e., chemical exposure) may play a more notable role. This study highlights the significance of understanding how chemical exposure drives disease outcomes and increases disease risk, especially for more virulent diseases that disproportionately (unequally) impact specific communities. Prior research infers differences in chemical exposure may explain racial disparities for several illnesses, and growing evidence suggests common chemical exposure patterns influence the risk of breast cancer. […]

(Beyond Pesticides, February 24, 2021) Soil sprayed with weedkillers glyphosate, glufosinate, or dicamba are likely to contain higher amounts of antibiotic resistant bacteria, according to research published earlier this month in the journal Molecular Biology and Evolution. Each year in the United States, at least 2 million people develop an antibiotic resistant infection, and over 23,000 die. Authors of the study say widespread herbicide use is likely playing a role. “Our results suggest that the use of herbicides could indirectly drive antibiotic resistance evolution in agricultural soil microbiomes, which are repeatedly exposed to herbicides during weed control,” said Ville Friman, PhD of the University of York in the United Kingdom. Scientists began their investigation by looking at changes to soil communities in soil microcosms over the course of a roughly two months. Microcosms were grouped by the herbicide applied, while a control microcosm remained unexposed. Each microcosm had a single herbicide applied at a rate reaching 10 parts per million (ppm) in soil. The researchers replicated each treatment 12 times. Contrary to the pesticide industry’s claim that these chemicals break down quickly and become inert by binding to soil particles, large proportions of the herbicides remained in the soil at […]

(Beyond Pesticides, January 28, 2021) Persistent organic pollutants (POPs)—including banned pesticides—present a health risk to the endangered Qinling Panda (Ailuropoda melanoleuca qinlingensis), the rarest subspecies of giant pandas, according to a new Chinese study published in Environmental Pollution. Organochlorine compounds (OCs), such as organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs), are well-known persistent organic pollutants. They were banned by the Stockholm Convention treaty in 2001 and are primary pollutants of concern (UNEP, 2009) because of their persistence, toxicity, and adverse effects on environmental and biological health. These pollutants have a global distribution, with evaporation and precipitation facilitating long-range atmospheric transport, deposition, and bioaccumulation of hazardous chemicals in the environment. The U.S. was a signatory to the treaty, but U.S. Senate never ratified it, relegating U.S. officials to observer status. Although various studies demonstrate the volatile, toxic nature of POPs, much less research evaluates the impact POPs have on biodiversity over time. The globe is currently going through the Holocene Extinction, Earth’s 6th mass extinction, with one million species of plants and animals at risk. With the increasing rate of biodiversity loss, advocates say it is essential for government agencies to research how previous and ongoing use of POPs can impact present-day species. Likewise, collaborative, […]

(Beyond Pesticides, January 22, 2021) After the past four devastating years, hopes and expectations of the Biden/Harris administration abound among the environmental and public health communities. The ears and eyes of many advocates, as well as those in the agricultural community, are attuned (among myriad candidates) to the fate of the pesticide aldicarb. Although Environmental Protection Agency (EPA) registration of this terribly toxic insecticide was cancelled in 2010, various limited-use reapprovals since then have meant that the compound has found its way to increasing levels of use. On January 12, as another parting shot of midnight rulemaking, Trump’s EPA approved expanded uses (see below). The $64,000 question is whether the new administration will use its authority under the Congressional Review Act — which enables Congress to pass a joint resolution (then signed by the President) to overturn a new federal agency rule and prevent its reissuance in the future — to get this pesticide retired for good. Beyond Pesticides urges President Biden’s EPA to do so. Notably, the Trump administration used the Congressional Review Act to destroy myriad environmental rules when it came into power. This permitting of expanded aldicarb uses fits the pattern. Environmental Health News notes that, as of early […]

(Beyond Pesticides, January 18, 2021) We honor Martin Luther King, Jr. today on Martin Luther King Day—a day of national service with volunteer opportunities across the nation. During this day of reflection, consider reading Dr. King’s “I Have a Dream Speech” or listening to it here. At Beyond Pesticides, our vision and work aligns with the vision Dr. King expressed—“Injustice anywhere is a threat to justice everywhere.” To that end, we seek to eliminate disproportionate risk, with elevated toxic hazards to people of color communities, with higher rates of pesticide-induced diseases among those who live in fenceline communities where chemicals are produced, among farmworkers who harvest the nation’s food, and among landscapers who manage our parks and children’s playing fields. We seek to transform national laws that allow risks under risk assessments that institutionalize environmental racism by allowing for this disproportionate risk. We seek to eliminate toxic pesticides production and use through the adoption of organic land management. To that end, we work with communities across the country to transition their land management to organic practices and we advance organic standards under the Organic Foods Production Act that have integrity and are fully enforced. Eliminating Toxic Pesticides with Organic Transformation […]

(Beyond Pesticides, December 14, 2020) As the President-elect chooses the leadership in his administration, it is critical that we in the affected communities establish our expectations of what is needed from agencies to address critical issues of the day. While we may feel that different choices of personnel could have been made, ultimately we are looking forward to advancing programs across all agencies that represent meaningful and foundational changes to our social, economic, and environmental norms. As we focus on the appointment of a Secretary of Agriculture, issues of foundational change come into sharp focus, relating to sustainable land management, distribution of resources and access to land, food security, protection of human and ecosystem health, and climate. It is normal, therefore, to look at any individual appointee’s past performance and positions as a measure of future decisions or policies that may be advanced. Ultimately, though, it is the administration that sets the tone, establishes a framework, and forges the direction of the government’s programs and policies. President-elect Biden has talked about a framework for policy to which we can and must hold all officials in the administration accountable across all agencies. These key elements of the framework intersect with the […]

(Beyond Pesticides, December 7, 2020) The Trump Environmental Protection Agency (EPA) reversed in four years much of the progress made by EPA in decades, and that push continues. The Biden EPA needs to advance a new vision. Tell President-elect Biden to adopt a new direction for pesticide regulation. Challenge so-called “benefits” of pesticides. The Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) requires EPA to weigh risks against benefits when registering pesticides. Claimed “benefits” for toxic pesticides need to be judged in comparison to organic production, which is able to produce all types of food and feed. The Organic Trade Association reports that organic sales now exceed $55 billion per year, and the U.S. Department of Agriculture (USDA) finds that organic producers in the U.S. produced $9.9 billion worth of organic food on 5.5 million acres in 2019. EPA assumes benefits of pesticides, rather than measuring them, and does not take into account the development of resistance. The cost-competitive success of organic food production and nonagricultural land management practices make the case that toxic pesticides lack benefits. Protect pollinators. Agriculture relies on insect pollinators to facilitate fertilization and maintain annual crop yield. Globally, the production of crops dependent on pollinators is worth […]

(Beyond Pesticides, November 30, 2020) The “environment” is central to President-elect Biden’s priorities: climate change, COVID-19, and the next pandemic, racial equity, and economic recovery. The new administration should include an EPA administrator who understands the relationships among these and other environmental issues and has a clear vision of the changes needed to dramatically change our course, currently heading for ecological destruction. Tell President-elect Biden to appoint an EPA Administrator who is an environmentalist with broad environmental credentials and a vision that embraces a dramatic transition away from hazardous chemicals and polluting practices at this perilous time. Let’s start with what the past four years has taught us about who we do NOT want as EPA Administrator. We do not want an industry lobbyist, someone whose work has been funded with industry money, who has represented industry in litigation or as a lobbyist, who has attacked environmentalists, or has never read Silent Spring. Such a person is not qualified to provide the leadership needed to address priority issues and understand the interconnections necessary to address the crises associated with climate, health, and biodiversity decline. On the other hand, a strong candidate will support holistic thinking, with an understanding of interrelationships in […]

(Beyond Pesticides, November 20, 2020) Many pet owners likely do not consider what is actually in the flea treatments they administer to their animals. That should change, and recent research demonstrates why. Scientists sampling rivers in England found extreme contamination with two neurotoxic pesticides commonly used in flea products for dogs and cats: fipronil and the neonicotinoid imidacloprid. In many instances, the concentrations in the waterways were far higher than accepted “safe” levels. Though these compounds are banned for agricultural uses in the United Kingdom (UK), risk assessment for them, as used on animals, has been minimal because of the assumption that the amounts used for veterinary treatments would mean far-less-significant environmental impact than might be expected with agricultural-scale use. This research out of the University of Sussex voids that assumption, and the researchers recommend “re-evaluation of the environmental risks posed by pet parasite products, and a reappraisal of the risk assessments that these products undergo prior to regulatory approval.”   Apart from being an active ingredient in flea treatments for pets, fipronil is used in insect baits, and in turf management and agriculture in the U.S. It is highly toxic to insects, including bees, to birds, and to aquatic invertebrates. […]

(Beyond Pesticides, November 5, 2020) Research at the University of California San Francisco (UCSF) finds that pesticide exposure increases the risk of developing Parkinson’s disease (PD), regardless of whether disease onset is idiopathic (spontaneous) or genetic (GBA genetic risk variant). Although the exact etiology of PD remains unknown, epidemiological and toxicological research repeatedly identifies exposure to pesticides, as well as specific gene-pesticide interactions, as significant adverse risk factors that contribute to PD. Furthermore, this study, “Gene Variants May Affect PD Risk After Pesticide Exposure,” suggests that environmental triggers like occupational exposure to pesticides can prompt PD in individuals with or without the genetic precursor. This research demonstrates the importance of assessing disease etiology concerning occupational pesticide exposure, especially if disease triggers are overwhelmingly non-hereditary. Since not all individuals genetically predisposed to the disease develop PD, with only 10 to 15 percent of PD cases being genetic, government officials need to consider alternate etiological pathways that include environmental risk factors. Study researchers note, “‘Environmental exposures may have differential effects in different genotypes’ and may predispose people with PD to different symptom burden.”  Parkinson’s disease is the second most common neurodegenerative disease, with at least one million Americans living with PD and about […]

(Beyond Pesticides, November 4, 2020) Despite a recent court ruling voiding the registration of drift-prone dicamba herbicides on genetically engineered (GE) cotton and soybeans, EPA has renewed  the registration of these chemicals. The court’s ruling stated that EPA, “substantially understated risks that it acknowledged and failed entirely to acknowledge other risks,” in regards to the herbicides XtendiMax and Eugenia (dicamba), produced by agrichemical corporations Bayer and BASF for their genetically engineered (GE) crops. In announcing the decision, Administrator Andrew Wheeler said the agency made its decision “[a]fter reviewing substantial amounts of new information, conducting scientific assessments based on the best available science, and carefully considering input from stakeholders.” Yet, it is evident that the most important stakeholders for EPA continues to be chemical corporations. The history of dicamba’s use in GE agriculture reveal this to be the case. In the mid-2010s, Bayer’s Monsanto developed new dicamba-tolerant seeds and received approval to sell them from the U.S. Department of Agriculture. EPA had not yet approved its corresponding herbicide, but nonetheless, Bayer’s Monsanto urged farmers to plant its seed, claiming they would increase yields. The results of this were predictable: farmers began to use older, unapproved dicamba formulations on their new GE […]

Application Exclusion Zones (AEZs) are buffer zones where individuals are not permitted to enter during a pesticide application, as doing so would put one at risk of dangerous exposure. EPA proposed, and has now finalized, a number of changes to the way AEZs work. The agency is: i) removing responsibility for chemical-intensive farms to keep bystanders out of off-site spray areas; ii) allowing pesticide applications to stop and start when individuals enter and exit AEZs (rather than establish set safety requirements); iii) exempting on-farm families from AEZ protections, allowing dangerous pesticide applications to take place near buildings and other shelters where family members reside within an AEZ (“rather than compelling them to leave even when they feel safe remaining inside,” the agency notes in a disturbingly unscientific fashion), and; iv) “simplifies” or weakens criteria around determining the appropriate buffer size for an AEZ. Industry began pushing rollbacks to farmworker protections early in the current administration, starting with the 2017 announcement under former Administrator Pruitt that EPA would revise Worker Protection Standards initially agreed upon under the Obama Administration.  Not all of these efforts were successful, however, as 28 Senators pushed back in a 2018 letter opposing the agency’s revisions. “These […]

(Beyond Pesticides, October 30, 2020) The European Union (EU) adopted, in mid-October, a new strategy on chemicals — including pesticides — that seeks to deal with their combined (synergistic) and cumulative impacts on human and environmental health. A highlight of the new strategy is the acceleration of work, already begun across the EU, to address the “chemical cocktail” impacts of pesticides and other chemicals. Human exposures to such “cocktails” can happen through use of multiple different agricultural pesticides that can persist as residues on food, and via industrial processes and consumer products. Beyond Pesticides has insisted for years that, here in the states, the Environmental Protection Agency (EPA) has been way behind the eight ball in dealing with the potential synergistic and cumulative impacts of the pesticides its registers for use. Advocates have argued that the agency must be far more rigorous in evaluating impacts of exposures to multiple pesticides, as well as cumulative impacts. The toxicity problem the EU seeks to address is that interacting chemicals can have synergistic effects, even at very low levels — effects greater than and/or different from the expected impacts of each chemical per se. Pesticides can also have cumulative “toxic loading” effects in both […]

(Beyond Pesticides, October 26, 2020) A high percentage of the disinfectants approved by EPA for use against coronavirus contain quaternary ammonia compounds (quats). EPA’s approved list is used by schools and other institutions—unfortunately, without guidance for avoiding harmful effects. Quats are very toxic. They are especially dangerous in the context of a respiratory pandemic. Quats increase the risk for asthma and allergic sensitization. Evidence from occupational exposures shows increased risk of rhinitis and asthma with exposure to quats. Quats are on the Association of Occupational and Environmental Clinics list of asthmagens and may be a more potent asthmagen than bleach. Tell the EPA and Congress that EPA must not recommend toxic disinfectants without the context of their damaging impacts and other necessary protective measures. One quat, benzalkonium chloride, has also been associated with dermatitis. Quats appear to be sensitizers and irritants to the skin and mucous membranes and are suspected to display an immunologic cross-reactivity between each other and with other chemical compounds containing ammonium ion. Quats also are mutagenic and reproductive toxicants. Some quats have shown to be mutagenic and to damage animal DNA and DNA in human lymphocytes at much lower levels than are present in cleaning chemicals. […]