(Beyond Pesticides, June 27, 2023) Pesticides interfere with biological processes. This is their purpose. Unfortunately, they nearly always have unintended consequences, many of which have been ignored by their manufacturers. A new review article by Irish and Dutch researchers in the ISME Journal adds to the emerging scientific literature examining how pesticides affect the relationship between the human gut and the human brain (the “gut-brain axis”). Often called the “second brain” because it houses nerve cells and produces neurotransmitters, the gut-brain axis may be the most important locus where microbes and pesticides meet. The human gut plays host to a variety of microorganisms, ranging from bacteria and archaea to fungi, viruses and yeasts.[1] In a healthy person these microbes remain in balance and often cooperate both with each other and with human cells. The gut and the brain are deeply integrated through the vagus nerve and the neuroendocrine system. The vagus nerve is a treelike bundle of fibers extending from the lower part of the brain to nearly every body organ, but particularly the heart, lungs and digestive tract. The neuroendocrine system comprises specialized cells inhabiting nearly all the organs of the body that respond to signals from the brain […]

(Beyond Pesticides, June 16, 2023) Juneteenth is a celebration of freedom for the last 250,000 enslaved people in Galveston, Texas, but it is also a reminder that justice has not historically been “swift” or complete for Black Americans. The holiday commemorates the abolition of slavery in Texas on June 19, 1865, two and a half years after the Emancipation Proclamation.  According to a 2022 Gallup Poll, 40 percent of Americans know “a little bit” or “nothing at all” about Juneteenth. While this is a significant improvement in comparison to the 60 percent for the aforementioned metric in the previous year (when the holiday was federally recognized), greater public awareness is needed. This holiday is a time for individuals and organizations to acknowledge and reflect on their past and current actions or inactions that perpetuate systemic racism. As known from the history books, the Emancipation Proclamation was signed on January 1, 1863, and the civil war ended on April 9, 1865. Juneteenth is a lesser-known anniversary commemorating the emancipation of enslaved people who received news of their freedom two and a half years after Abraham Lincoln’s freedom proclamation. While the technologies in the 19th century had a much slower travel time, […]

(Beyond Pesticides, June 14, 2023) A study published in Scientific Reports finds a link between pesticide exposure and recurrent pregnancy loss (RPL) through oxidative stress and apoptosis (cell death) in the placenta. Recurrent pregnancy loss (RPL) is the loss of three or more successive pregnancies before 24 weeks of gestation (pregnancy) and signifies an underlying reproductive health issue. The study highlights that pesticides’ endocrine-disrupting (ED) properties can have varying adverse impacts on biological processes, including immunology, metabolism, and reproduction. Pregnant women experience frequent exposure to environmental pollutants that pose serious health risks to both mother and newborn. Many known pollutants (e.g., heavy metals, polychlorinated biphenyl, and pesticides) are chemicals with ED properties that can move from the mother to the developing fetus at higher exposure rates. Additionally, pregnant women are experiencing exposure to an increasing number of dangerous industrial chemicals. With a range of scientific data highlighting chemical exposures during pregnancy as a critical window of vulnerability, public awareness of these threats is growing. The study notes, “They are associated with an increasing placental OS [oxidative stress] and placental apoptosis. Specific measures should be taken to decrease maternal exposure to these pollutants’ sources, especially in underdeveloped and developing countries.” For RPL, the research investigated pesticide components in blood plasma, […]

(Beyond Pesticides, June 9, 2023) Glyphosate, usually marketed as the herbicide Roundup, has long been the poster child for shoddy regulation by both the U.S. Environmental Protection Agency (EPA) and the European Food Safety Authority (EFSA). In a study published June 1, 2023 in Environmental Health by Axel Mie and Christina Rudén, PhD, of Stockholm University and the Centre for Organic Food and Farming in Uppsala, the authors followed up on earlier work that documented deficiencies in information provided to European Union (EU) regulators by manufacturers. They identified nine studies on developmental neurotoxicity (DNT) that had been submitted to the U.S. Environmental Protection Agency (EPA) but were not disclosed to EU authorities. According to the research, seven of these studies would have “actual or potential regulatory impact.” According to the authors: “Of the nine undisclosed DNT studies, three were sponsored by Bayer and performed in their own laboratory. Three studies were sponsored by Syngenta and performed in their Central Toxicology Laboratory. One study each was sponsored by Nissan Chemicals and Ishihara Sangyo Kaisha (ISK), and these were performed at Huntingdon Life Sciences. For the remaining study, the sponsor and laboratory are unknown to us.” This study is a new example […]

(Beyond Pesticides, June 5, 2023) Butterflies—the most attractive of our insect fauna—are disappearing at an appalling rate, largely due to pesticide use. Recent studies have documented declines of almost 50% from 1990 to 2011 in Europe (with trends continuing), of 58 percent between 2000 and 2009 in the U.K., and of 33% from 1996–2016 in the state of Ohio in the U.S. Even steeper declines have been documented for Monarch butterflies, with an 80 percent decline of Eastern monarchs and 99 percent decline of Western monarchs. Tell EPA to eliminate pesticides that threaten butterflies. Tell the U.S. Fish and Wildlife Service and Department of Interior to help bring back butterflies by eliminating the use of pesticides that threaten them. Tell Congress that EPA and other agencies need to do their job and protect our most charismatic insects. Last year, EPA admitted that three neonicotinoid pesticides are “likely to adversely affect from two-thirds to over three-fourths of America’s endangered species—1,225 to 1,445 species in all,” including many butterfly species. On May 5 of this year, EPA released new analyses of these neonics’ effects on endangered species. EPA’s analyses focus on the species most at risk of extinction, and the results represent […]

(Beyond Pesticides, June 2, 2023) Scientists have identified 97 different types of pesticides and flame retardants in primate fecal samples, recently reporting their results in the journal Biology Letters. In Uganda’s Kibale National Park, researchers studied the chemical exposure of four species of primates (chimpanzees, Ugandan red colobus, olive baboons and red-tailed monkeys), adding to previous research on the subject. The chemicals demonstrate a measurable effect on primate growth and development, sparking considerable unease as to the future health of these critical species. This study shows how even within a protected national park, wildlife species are at risk from chemical pollution. According to advocates, the use of dangerous pesticides and flame retardants, therefore, must be entirely stopped in order to protect the future viability of wildlife species.  Scientists collected a total of 71 fecal samples from the four chosen species to measure levels of chemicals and hormones in a noninvasive manner. After sample analysis, researchers highlight three main groups of chemical pollutants: organochlorine pesticides (OCPs), brominated flame retardants (BFRs), and organophosphate esters (OPEs). Although in a protected area, wildlife species encounter humans through tourism, research, and human development surrounding the park. As these pesticides are so prevalent in areas of […]

Eco-Friendly Parks for All (EFPA)*, a coalition of environmental, public health and political action organizations, has teamed up with Beyond Pesticides, New York City Parks and Recreation Department, and Stonyfield Organic Yogurt to celebrate the success of pilot organic land management programs at eight sites across the five boroughs. 

(Beyond Pesticides, May 31, 2023) A study published in Chemosphere supports accumulating scientific research confirming that prohibited and current use pesticides are readily detectable in the human placenta. All pregnant women experience exposure to a mixture of complex pesticides like DDT (prohibited organochlorine pesticide [OCP]) and chlorpyrifos (current use organophosphate [OP]), with concentrations high enough to increase possible adverse health risks to the fetus through a placental transfer of chemicals. Prenatal development in the intrauterine environment is one of the most vulnerable periods of exposure, as the fetus is most susceptible to the harmful effects of chemical contaminants. Many studies indicate that prenatal and early-life exposure to environmental toxicants increases susceptibility to diseases, from learning and developmental disabilities to cancer. Given the over 1,300 research studies that demonstrate the link between pesticide exposure and general health effects, studies like this can help government and health officials identify how pesticides’ impact on the body elevates health concerns, especially for future and developing generations. The authors note, “This study highlights the urgent requirement for implementing alternative pest-control methods in agriculture, involving a reduction of chemical pesticides application. Due to the vital role of the placenta in fetal development and its non-invasive sampling, this kind of […]

(Beyond Pesticides, May 23 2023) New research is zeroing in on the role of 10 commonly used pesticides in the development of Parkinson’s. Published in the journal Nature Communications by a team of scientists lead by researchers at the University of California, Los Angeles, the study focused on the toxicity of these pesticides to neurons that have been found to lead to the presentation of the disease. Research is increasingly focusing on environmental exposures, and pesticides in particular, as a major factor in the development of Parkinson’s. This study adds further evidence that this line of research is a valid and worthwhile undertaking for the nearly one million people in the United States struggling with this incurable disease. [The authors note that the herbicide paraquat’s strong connection to Parkinson’s is not addressed in this study, but is the focus of a separate manuscript.] Scientists sought to further focus on which pesticides were most likely to be playing a role in Parkinson’s development. Records from California’s vast pesticide use database aided the search. From a comprehensive pesticide-wide association study, 53 of 288 pesticides screened were found to be linked to Parkinson’s. Scientists then took these 53 pesticides and conducted live-cell imaging […]

(Beyond Pesticides, May 22, 2023) Since most of the domestically produced fresh produce we eat comes from California, what happens in the state is of concern to most consumers. The California Department of Pesticide Regulation (DPR) has made minor adjustments to its proposal to remove existing limits on the use of 1,3-dichloropropene (1,3-D or Telone), allowing Californians to breathe much more 1,3-D than state toxicologists at the California Office of Environmental Health Hazard Assessment—charged with establishing safe limits of exposure and enforcing Prop 65—say is safe, highlights the dangers to which farmworkers are routinely exposed. It is outrageous that the U.S. Environmental Protection Agency (EPA) would allow farmworkers—whose labor was judged “essential” during the pandemic—to be routinely exposed to highly toxic pesticides, which could be replaced by organic practices. You may have commented on this early in the year, and now we need to follow up with a strong message to protect those who harvest the nation’s food.  Tell EPA, Congress, and CDPR to cancel the registration of all toxic soil fumigants and encourage organic alternatives. 1,3-D is a pre-plant soil fumigant registered for use on soils to control nematodes. It is allowed on all crops and is often used with chloropicrin, another highly toxic […]

(Beyond Pesticides, May 18, 2023) A study published in Food and Chemical Toxicology finds pesticide residues in beehive products pose a safety risk from dietary consumption. Beehive products (i.e., bee bread, propolis, beeswax, and royal jelly) from beekeeping or apiculture are said to have nutraceutical (health and medicinal benefits) properties. However, a wide range of pesticide residues (i.e., tau-fluvalinate, coumaphos, chlorfenvinphos, chlorpyrifos, and amitraz), especially acaricides for killing ticks and mites in hives, may accumulate in beehive products up to concentrations that pose a potential health risk. Environmental contaminants like pesticides are ubiquitous in the environment, with 90 percent of Americans having at least one pesticide compound in their body. Many of these chemical compounds remain in soils, water (solid and liquid), and the surrounding air at levels exceeding U.S. Environmental Protection Agency (EPA) standards. Therefore, individuals still encounter pesticide compounds at varying concentrations, adding to the toxic body burden of those harmful chemicals currently in use. The research methodology includes a review of the scientific literature on pesticide contamination in hive products and a dietary risk assessment. The risk assessment calculation uses scientific studies to determine the recommended daily intake values and concentration data. Researchers compare exposure values in products to health-based guidance, determining the potential acute and […]

(Beyond Pesticides, May 17, 2023) British biotechnology company Oxitec is withdrawing its application to release billions of genetically engineered mosquitoes in California, according to a recent update from the California Department of Pesticide Regulation. The withdrawal is a victory for environmental and health campaigners concerned about the release of a novel mosquito that the U.S. Environmental Protection Agency (EPA) had previously authorized under an “experimental use” permit. “Genetically engineered mosquitoes are an environmental justice issue for Tulare County residents who should not be human experiments,” said Angel Garcia, codirector of the statewide coalition Californians for Pesticide Reform and Tulare County resident in a press release. “We are already impacted by some of the worst pollution problems in the state and deserve prior informed consent to being part of an open-air biopesticide experiment. Ahead of any future proposal for genetically engineered insects, DPR needs to have robust regulations in place that protect community members, and meaningful, inclusive public participation in any decision making.”     Oxitec began releasing its GE mosquitoes over a decade ago, first introducing the insects in the Brazilian town of Itaberaba. The company has made efforts to launch its mosquitoes in the United States, likely as a way […]

(Beyond Pesticides, May 15, 2023) Say “legacy contaminant” or “forever chemical” and most people today think “PFAS” (perfluoroalkyl substances), but PFAS are just the latest persistent toxic chemicals recognized as presenting an alarmingly difficult cleanup problem. Fortunately, steps are being taken by governments and businesses to eliminate use of PFAS. (Organic farmers concerned about the integrity of their products have been leaders in these efforts.) Although government officials often devote considerable energy and resources to cleaning up contamination, the continued manufacturing of these chemicals and their release into the environment creates a futile situation. The U.S. is a signatory to the 2001 Stockholm Convention, which provides an international framework for moving persistent organic pollutants out of commerce, but the U.S. Senate never ratified it.     Ask your Senators to ratify the Stockholm convention. Tell EPA that persistent toxic pesticides must be considered to pose an “unreasonable risk to the environment under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA),” which must result in cancellation of their registrations.  PFAS contamination is just the latest chapter of a very old story. Legacy contamination of our bodies and the environment is partly a result of a slow piecemeal approach to eliminating these toxic chemicals. […]

(Beyond Pesticides, May 12, 2023) With the growth of chemical-intensive land management over the last century, the world has been held captive by pesticide companies. For part of that time, it could be said the modern society has suffered from Stockholm Syndrome, a theory about abusive relationships in which one party exerts power over the other using threats, fear, and lies and the victim comes to depend on the perpetrator emotionally. During the so-called “Green Revolution” (circa 1945-1985), the world came to depend on vast amounts of fertilizers and herbicides, insecticides, and fungicides. Many people believed that food, clothing, and shelter made from naturally-occurring materials such as fruit, flax and wood could not be provided to the world without pesticides. It seemed that science and commerce could indefinitely raise the standard of living around the world, perhaps leading to world peace. This is not what happened. Soon observers noticed the harmful effects of many pesticides, including their persistence in the environment, their tendency to accumulate in the bodies of humans and wildlife, and their influence on the risk of contracting many diseases, from cancer to asthma—not to mention the Darwinian inevitability of pest resistance. By the turn of the 20th […]

(Beyond Pesticides, May 9, 2022) The Colorado legislature last week passed SB23-266, a bill limiting the use of bee-toxic neonicotinoid pesticides in the state. The news comes as other states consider their own restrictions, and the U.S. Environmental Protection Agency (EPA) is publishing details on exactly which endangered species are set to be harmed by the ongoing use of these harmful insecticides. This latest news shows that protecting pollinators is possible, and urgently needed given growing understanding of the dangers these chemicals pose to the most vulnerable wildlife in the country.   The Colorado bill requires the state’s commissioner of agriculture to adopt rules designating neonicotinoid pesticides as ‘limited-use’ pesticides in the state. With this designation, only licensed pesticide dealers may sell products containing these chemicals. Per the state’s legal code, the “limited-use” designation means the same as a federal “restricted-use” pesticide, which permits sales and use only for certified applicators. Passage of this bill marks an important step forward for pollinator protection efforts in the state. It will help ensure that homeowners are not able to easily purchase this product at big box retailers, but will allow continued use in residential areas and in agriculture. Colorado’s bill fulfills guidance […]

(Beyond Pesticides, May 5, 2023) Low level exposure to pyrethroid insecticides found in common pesticide brands like RAID and ORTHO result in neurodevelopmental damage to laboratory animals, reinforcing evidence of harm found in epidemiological studies on human exposure to these chemicals. According to research published in PNAS Nexus, mice exposed to the pyrethroid deltamethrin displayed atypical behavior similar to humans with developmental disorders. “We are not saying these mice have autism or that they have ADHD. That’s not the goal here,” said James Burkett, PhD, study coauthor and assistant professor of neuroscience in the UToledo College of Medicine. “What we are saying is that something in their brain has been altered by this exposure and it’s resulting in the same kinds of behaviors that we see in children with autism.” Scientists arrived at this determination by exposing a group of mouse mothers to consistent low levels of deltamethrin in their food during preconception, pregnancy, and lactation. The study notes that the amount of pesticide provided was “well below the benchmark dose for regulatory guidance.” A separate control group was given no pesticide in its food. Offspring from the female mice were then put through behavioral tests on social behavior, restrictive […]

(Beyond Pesticides, May 4, 2023) One of the most widely used insecticides in California, Intrepid 2F, contains harmful levels of per- and polyfluoroalkyl substances (PFAS), or “forever chemicals,” according to a report by the Center for Biological Diversity (CBD) and Public Employees for Environmental Responsibility (PEER). In fact, 40 percent of pesticide products in the report tested positive for high levels of PFAS. PFAS are common in non-stick cookware, cleaning/personal care products, food packaging, and other consumer products. However, these compounds are also in pesticide products. Despite evidence on the dangers of PFAS stretching as far back as the 1950s, federal agencies sat by the sidelines as the plastics industry continued adding the material to new products. From widespread presence in farm fields and sewage sludge to contaminated water bodies throughout the U.S., PFAS has made its way into the environment and our bodies. PFAS are even present in remote environments like the Arctic, Antarctica, and Eastern European Tibetan Plateau. A study published in 2020 identified PFAS as common products to which Americans are exposed daily. The U.S. Centers for Disease Control and Prevention (CDC) determined that 98% of Americans have some level of PFAS in their bloodstream, with studies reporting PFAS compounds are detectable in infants, children, and pregnant women. With […]

(Beyond Pesticides, April 28, 2023) A study published in Science of The Total Environment finds agricultural communities encounter chronic and measurable pesticide exposure regardless of seasonal pesticide applications. Several biomonitoring studies demonstrate people living adjacent to or within agricultural areas often experience elevated levels of organophosphate (OP) insecticides, even while not working directly with OPs. Six dialkyl phosphate (DAP) metabolites (breakdown products) of OPs persist in urine during the spraying and non-spraying seasons. Despite 75 percent of OPs metabolizing into one or more of the six DAPs and excreting within six to 24 hours after exposure, the consistent levels of DAPs in urine highlight continuous exposure beyond regular seasonal pesticide applications. OP compounds have a global distribution, with evaporation and precipitation facilitating long-range atmospheric transport, deposition, and bioaccumulation of hazardous chemicals in the environment. OPs are highly toxic and, as this study shows, residues are consistently present in human and animal urine, as well as blood, tissues, and milk. Considering 90 percent of Americans have at least one pesticide compound in their body, primarily stemming from dietary exposure, including food and drinking water, advocates maintain that current restrictions on their use must adequately detect and assess total chemical contaminants. The study notes, “We suggest that among agricultural communities that experience […]

(Beyond Pesticides, April 27, 2023) The Nevada Assembly, by unanimous vote, took the state one step closer to banning the use of neonicotinoid insecticides used on plants, with a waiver for commercial agricultural purposes. Despite dramatic declines in bee populations linked to neonicotinoid pesticides and other toxic pesticides, the U.S. Environmental Protection (EPA) and state regulatory authorities have for the most part ignored beekeepers and the independent scientific literature by allowing widespread toxic pesticide use—forcing elected officials to take protective action. Portions of the bill would take effect upon passage or no later than January 1, 2024. Maine and New Jersey have adopted similar legislation. The failure to adequately regulate pesticides under federal law, the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), and EPA inaction is viewed by environmentalists as the shocking disregard for the importance of biodiversity to sustaining life. The inadequate restriction of pesticides and slower than necessary transition to organic land management practices are viewed as major contributors to the “insect apocalypse.” The legislation (A.B. 162), led by Assemblywoman Michelle Gorelow and a group of nine other Assemblymembers, illustrates a growing trend of local and state legislative bodies asserting their authority to protect against health, biodiversity, and […]

(Beyond Pesticides, April 18, 2023) Health officials in France are alerting the public that a majority of drinking water samples tested by the government contain the presence of the highly toxic fungicide chlorothalonil. The findings highlight a stark divide between regulations and public health management in the European Union and United States. While EU member states have banned this chemical and are working to understand and address lingering effects, tens of millions of pounds of chlorothalonil continue to be sprayed throughout the U.S. annually. French officials say they conducted this research after researchers in Switzerland found evidence of the fungicide in drinking water. A few years ago, Swiss scientists released a report showing Evian bottled water, touted for its claims of purity, was found to contain measurable levels of chlorthalonil.  “The fact that even the Evian springs in the French Alps, which are hardly affected by humans, contain pesticide residues is alarming and shows the far too careless handling of these substances,” Roman Wiget, president of the international drinking water association AWBR told the German-language Swiss weekly at the time. The EU banned uses of chlorothalonil in 2019, due to concerns over water contamination, the effects of such contamination on fish […]

(Beyond Pesticides, April 14, 2023) In March, scientists at the National Marine Fisheries Service (NMFS) issued a draft Biological Opinion (BiOp) stating that carbaryl and methomyl — two commonly used carbamate insecticides — cause significant harm to dozens of already-endangered fish species in the Pacific Northwest’s Columbia, Willamette, and Snake rivers. The BiOp indicates that these toxic compounds, in wide use on orchards and field vegetables throughout the Willamette Valley, the Columbia River Gorge, and southeastern Washington, will likely threaten scores of species on the Endangered Species list: 37 species at risk from carbaryl and 30 from methomyl. In addition, the BiOp says, “both are likely to harm or destroy many areas designated as critical habitat for endangered species.” The mitigation measures proposed by NMFS and the U.S. Environmental Protection Agency (EPA), in light of this BiOp, are likely to be inadequate to the problem, given that both compounds can drift through air and/or migrate into groundwater and generate toxic runoff. These two neurotoxic insecticides, carbaryl and methomyl, are very toxic to bees, birds, fish, and other aquatic organisms. In addition, carbaryl is a likely human carcinogen and an endocrine disruptor, and has harmful impacts on multiple bodily systems. Methomyl is […]

(Beyond Pesticides, March 30, 2023) A study published in Ecotoxicology and Environmental Safety finds that the commonly used herbicide, atrazine, promotes breast cancer development through suppression of immune cell stimulation, and thus function, and upregulation of enzymes mediating tumor development. According to the Centers for Disease Control and Prevention (CDC), breast cancer is a disease that causes breast cells to grow out of control, with the type of breast cancer depending on the cells themselves. Several studies and reports, including U.S. Environmental Protection Agency (EPA) data, identify hundreds of chemicals as influential factors associated with breast cancer risk. Breast cancer is the most common cancer among women, causing the second most cancer-related deaths in the United States. Past studies suggest genetic inheritance factors influence breast cancer occurrence. However, genetic factors only play a minor role in the incidence of breast cancer, while exposure to external environmental factors (i.e., chemical exposure) appears to play a more notable role. One in ten women will receive a breast cancer diagnosis, and genetics can only account for five to ten percent of cases. There are grave concerns over exposure to endocrine (hormone) disrupting chemicals and pollutants that cause adverse health effects. Therefore, advocates point to the need for national […]

(Beyond Pesticides, March 29, 2023) A commonly used slug killer known as metaldehyde can hamper the growth of garden vegetables. This finding, published in the journal Scientific Reports, provides a helpful reminder for gardeners to seek out non and less toxic management approaches as spring comes into full swing and pests arrive. While slugs can be devastating to seedlings this time of the year, some simple approaches can help reduce pest pressure while maintaining the quality and integrity of one’s garden plot. Metaldehyde is a molluscicide that is applied through a bait, causing slugs to expel mucus and completely dry out. It has been in use since the 1940s, but like many pesticides from that era, there are a range of hazardous impacts that were not adequately studied at the time and are only beginning to be understood today. In mammals, ingestion of the chemical has been linked to neurotoxicity, including tremors, loss of coordination, rapid breathing and heart rate, vomiting, seizures and even death. Although humans are less likely to eat the baits, these risks are particularly pronounced for children and pets. Data on the impacts this material poses to plant growth is few and far between. To remedy […]