(Beyond Pesticides, May 4, 2023) One of the most widely used insecticides in California, Intrepid 2F, contains harmful levels of per- and polyfluoroalkyl substances (PFAS), or “forever chemicals,” according to a report by the Center for Biological Diversity (CBD) and Public Employees for Environmental Responsibility (PEER). In fact, 40 percent of pesticide products in the report tested positive for high levels of PFAS. PFAS are common in non-stick cookware, cleaning/personal care products, food packaging, and other consumer products. However, these compounds are also in pesticide products. Despite evidence on the dangers of PFAS stretching as far back as the 1950s, federal agencies sat by the sidelines as the plastics industry continued adding the material to new products. From widespread presence in farm fields and sewage sludge to contaminated water bodies throughout the U.S., PFAS has made its way into the environment and our bodies. PFAS are even present in remote environments like the Arctic, Antarctica, and Eastern European Tibetan Plateau. A study published in 2020 identified PFAS as common products to which Americans are exposed daily. The U.S. Centers for Disease Control and Prevention (CDC) determined that 98% of Americans have some level of PFAS in their bloodstream, with studies reporting PFAS compounds are detectable in infants, children, and pregnant women. With […]

(Beyond Pesticides, April 28, 2023) A study published in Science of The Total Environment finds agricultural communities encounter chronic and measurable pesticide exposure regardless of seasonal pesticide applications. Several biomonitoring studies demonstrate people living adjacent to or within agricultural areas often experience elevated levels of organophosphate (OP) insecticides, even while not working directly with OPs. Six dialkyl phosphate (DAP) metabolites (breakdown products) of OPs persist in urine during the spraying and non-spraying seasons. Despite 75 percent of OPs metabolizing into one or more of the six DAPs and excreting within six to 24 hours after exposure, the consistent levels of DAPs in urine highlight continuous exposure beyond regular seasonal pesticide applications. OP compounds have a global distribution, with evaporation and precipitation facilitating long-range atmospheric transport, deposition, and bioaccumulation of hazardous chemicals in the environment. OPs are highly toxic and, as this study shows, residues are consistently present in human and animal urine, as well as blood, tissues, and milk. Considering 90 percent of Americans have at least one pesticide compound in their body, primarily stemming from dietary exposure, including food and drinking water, advocates maintain that current restrictions on their use must adequately detect and assess total chemical contaminants. The study notes, “We suggest that among agricultural communities that experience […]

(Beyond Pesticides, April 27, 2023) The Nevada Assembly, by unanimous vote, took the state one step closer to banning the use of neonicotinoid insecticides used on plants, with a waiver for commercial agricultural purposes. Despite dramatic declines in bee populations linked to neonicotinoid pesticides and other toxic pesticides, the U.S. Environmental Protection (EPA) and state regulatory authorities have for the most part ignored beekeepers and the independent scientific literature by allowing widespread toxic pesticide use—forcing elected officials to take protective action. Portions of the bill would take effect upon passage or no later than January 1, 2024. Maine and New Jersey have adopted similar legislation. The failure to adequately regulate pesticides under federal law, the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), and EPA inaction is viewed by environmentalists as the shocking disregard for the importance of biodiversity to sustaining life. The inadequate restriction of pesticides and slower than necessary transition to organic land management practices are viewed as major contributors to the “insect apocalypse.” The legislation (A.B. 162), led by Assemblywoman Michelle Gorelow and a group of nine other Assemblymembers, illustrates a growing trend of local and state legislative bodies asserting their authority to protect against health, biodiversity, and […]

(Beyond Pesticides, April 18, 2023) Health officials in France are alerting the public that a majority of drinking water samples tested by the government contain the presence of the highly toxic fungicide chlorothalonil. The findings highlight a stark divide between regulations and public health management in the European Union and United States. While EU member states have banned this chemical and are working to understand and address lingering effects, tens of millions of pounds of chlorothalonil continue to be sprayed throughout the U.S. annually. French officials say they conducted this research after researchers in Switzerland found evidence of the fungicide in drinking water. A few years ago, Swiss scientists released a report showing Evian bottled water, touted for its claims of purity, was found to contain measurable levels of chlorthalonil.  “The fact that even the Evian springs in the French Alps, which are hardly affected by humans, contain pesticide residues is alarming and shows the far too careless handling of these substances,” Roman Wiget, president of the international drinking water association AWBR told the German-language Swiss weekly at the time. The EU banned uses of chlorothalonil in 2019, due to concerns over water contamination, the effects of such contamination on fish […]

(Beyond Pesticides, April 14, 2023) In March, scientists at the National Marine Fisheries Service (NMFS) issued a draft Biological Opinion (BiOp) stating that carbaryl and methomyl — two commonly used carbamate insecticides — cause significant harm to dozens of already-endangered fish species in the Pacific Northwest’s Columbia, Willamette, and Snake rivers. The BiOp indicates that these toxic compounds, in wide use on orchards and field vegetables throughout the Willamette Valley, the Columbia River Gorge, and southeastern Washington, will likely threaten scores of species on the Endangered Species list: 37 species at risk from carbaryl and 30 from methomyl. In addition, the BiOp says, “both are likely to harm or destroy many areas designated as critical habitat for endangered species.” The mitigation measures proposed by NMFS and the U.S. Environmental Protection Agency (EPA), in light of this BiOp, are likely to be inadequate to the problem, given that both compounds can drift through air and/or migrate into groundwater and generate toxic runoff. These two neurotoxic insecticides, carbaryl and methomyl, are very toxic to bees, birds, fish, and other aquatic organisms. In addition, carbaryl is a likely human carcinogen and an endocrine disruptor, and has harmful impacts on multiple bodily systems. Methomyl is […]

(Beyond Pesticides, March 30, 2023) A study published in Ecotoxicology and Environmental Safety finds that the commonly used herbicide, atrazine, promotes breast cancer development through suppression of immune cell stimulation, and thus function, and upregulation of enzymes mediating tumor development. According to the Centers for Disease Control and Prevention (CDC), breast cancer is a disease that causes breast cells to grow out of control, with the type of breast cancer depending on the cells themselves. Several studies and reports, including U.S. Environmental Protection Agency (EPA) data, identify hundreds of chemicals as influential factors associated with breast cancer risk. Breast cancer is the most common cancer among women, causing the second most cancer-related deaths in the United States. Past studies suggest genetic inheritance factors influence breast cancer occurrence. However, genetic factors only play a minor role in the incidence of breast cancer, while exposure to external environmental factors (i.e., chemical exposure) appears to play a more notable role. One in ten women will receive a breast cancer diagnosis, and genetics can only account for five to ten percent of cases. There are grave concerns over exposure to endocrine (hormone) disrupting chemicals and pollutants that cause adverse health effects. Therefore, advocates point to the need for national […]

(Beyond Pesticides, March 29, 2023) A commonly used slug killer known as metaldehyde can hamper the growth of garden vegetables. This finding, published in the journal Scientific Reports, provides a helpful reminder for gardeners to seek out non and less toxic management approaches as spring comes into full swing and pests arrive. While slugs can be devastating to seedlings this time of the year, some simple approaches can help reduce pest pressure while maintaining the quality and integrity of one’s garden plot. Metaldehyde is a molluscicide that is applied through a bait, causing slugs to expel mucus and completely dry out. It has been in use since the 1940s, but like many pesticides from that era, there are a range of hazardous impacts that were not adequately studied at the time and are only beginning to be understood today. In mammals, ingestion of the chemical has been linked to neurotoxicity, including tremors, loss of coordination, rapid breathing and heart rate, vomiting, seizures and even death. Although humans are less likely to eat the baits, these risks are particularly pronounced for children and pets. Data on the impacts this material poses to plant growth is few and far between. To remedy […]

(Beyond Pesticides, March 28, 2023) High concentrations of fully intact, never broken down DDT remain on the California seafloor decades after it was dumped off its southern coast in the middle of the 20th century. “We still see original DDT on the seafloor from 50, 60, 70 years ago, which tells us that it’s not breaking down the way that [we] once thought it should,” University of California Santa Barbara scientist David Valentine, PhD, told the Los Angeles Times. “And what we’re seeing now is that there is DDT that has ended up all over the place, not just within this tight little circle on a map that we referred to as Dumpsite Two.” These findings underscore the enormity of legal and regulatory decisions to approve production of hazardous chemicals. While many may believe the legacy of DDT ended with its ban in the early 1970s, the California findings raise a deeper problem not only with U.S. chemical policy, but also the response from well-meaning environmental nonprofits that continues to play out to this day. As many in the environmental community invest tremendous resources in seeking to ban problematic pesticides or chemicals of the day after the contamination has occurred […]

(Beyond Pesticides, March 27, 2023) In a move labeled “risk mitigation”—that is, mitigation of the risk to its shareholders—Bayer-Monsanto announced in 2021 that it would phase out Roundup™ products containing glyphosate for the residential lawn and garden market as of January 2023. In taking this action, Bayer-Monsanto is making no admissions, and glyphosate products will still be available to farmers. However, Lowe’s and Home Depot are still selling the glyphosate-based lawn and garden products. Tell Lowe’s and Home Depot to eliminate Roundup™ and other toxic pesticides, promote organic practices, and sell organic compatible products.  In fact, since this is a voluntary reformulation, and Bayer-Monsanto has decided its own timing, the company cannot be held accountable to anything. The company could change its mind, and stores can continue to sell the glyphosate-based products as long as they want. And keep in mind that replacement versions of Roundup™ products are also toxic. Roundup® Dual Action, for example, contains the following active ingredients: triethylamine salt of triclopyr, fluazipop-P-butyl, diquat dibromide, and ammonium salt of imazapic. Thus, Bayer/Monsanto announces that it is changing the formulation of Roundup and moving away from glyphosate, while continuing to sell Roundup™ products formulated both with and without glyphosate—leaving consumers unaware of their risks. The U.S. Environmental Protection Agency (EPA) has […]

(Beyond Pesticides, March 23, 2023) A case report article published in Frontier in Public Health confirms one of the first reported deaths from inhalation of the fumigant 1,3-dichloropropene (1,3-D or Telone) during work, resulting in acute renal (kidney) failure, hyperkalemia (high potassium levels in the blood), and brain edema (swelling). 1,3-D is a highly toxic fumigant used on a variety of crops, but primarily on potatoes, tobacco, strawberries, peanuts, and tomatoes to manage unwanted nematodes in soils. The chlorine-containing compound used in a greenhouse space entered the body of a 50-year-old man in China, being absorbed through the respiratory tract. Despite dilution from his wife, the compound was still strong enough to cause harm to human health. Without proper ventilation and personal protective equipment, wearing merely a surgical mask did not adequately defend against exposure to 1,3-D. This case represents the broader issue of how toxic chemical compounds can enter the body, causing physiological damage. Specifically, pesticides can increase the permeability (absorptiveness) of the blood-brain barrier that filters various molecules entering the brain from the circulatory system. However, the permeation of pesticide molecules elevates the expression and accumulation of soluble proteins in the brain involved in neuroinflammation, which plays a critical role in […]

(Beyond Pesticides, March 14, 2023) A study published in Environmental Research and Public Health finds occupational pesticide exposure increases the risk of sleep disorders among farmworkers and pesticide applicators. Specifically, many pesticides, like organophosphates (OPs), are detrimental to neurological function through inhibition of the enzyme acetylcholinesterase (AChE) responsible for ending a neurotransmission event after relaying the necessary information. Without an end to neurotransmission events, individuals experience a buildup of acetylcholine, resulting in convulsions, headaches, weakness, impacts on bodily senses, and other cognitive/mental changes. In addition to illnesses from chemical exposure, inadequate sleep has links to several chronic diseases like type 2 diabetes, cardiovascular disease, obesity, and depression. Therefore, given research links to sleep-related disorders and bodily functions, including endocrine, metabolic, neurological, and cognitive disorders, studies like this can help government and health officials identify how pesticides’ impact on the brain elevates health concerns. The study notes, “The study’s findings can be used to create strategies for addressing mental health issues and promoting mental health and quality of life.” Researchers assess the sleep patterns among individuals living in southeast Spain, near the coast of Almeria, where chemical-intensive agriculture from greenhouses is prevalent. Of the 380 participants in the study, 189 were […]

(Beyond Pesticides, March 9, 2023) A study published in Environmental Research finds exposure to organophosphate (OP) compounds during pregnancy, or prenatal OP exposure can cause shortfalls in language development abilities at 18 months, stifling preschool-age language expression. Additionally, a timely and co-occurring study published in Environmental International confirms similar results, highlighting that chlorpyrifos (an organophosphate) impedes neurological and psychological development, including language communication and all motor skills of offspring at 12 and 18 months old. Prenatal development is one of the most vulnerable periods of exposure, as the fetus is most susceptible to the harmful effects of chemical contaminants. Many studies indicate that prenatal and early-life exposure to environmental toxicants increases susceptibility to diseases, from learning and developmental disabilities to cancer. Given research links to pesticide exposure and neurological and cognitive development, studies like this can help government and health officials identify how pesticides’ impact on the brain elevates health concerns. The Environmental Research authors note, “The etiology [cause] of language development is complex, and this work further highlights the importance of the prenatal environment as a mechanism of influence that are associated with deficits in early language acquisition and ability, which could signal increased behavioral problems and academic difficulties in later childhood that extend […]

(Beyond Pesticides, March 7, 2023) An old Kerr-McGee Wood Treatment Facility is still causing health issues among residents in Springfield, Missouri. The former site of pressure-treated railroad tie production remains contaminated with creosote, a concoction of dangerous chemicals including polycyclic aromatic hydrocarbons, phenols, and creosols. While residents are still dealing with lingering effects of a now shuttered production site, the U.S. Environmental Protection Agency (EPA) is set to reregister creosote (wood preservatives are regulated as pesticides in the U.S.), perpetuating the harm caused by this material despite the wide availability of alternatives. The wood treatment facility in question operated for nearly 100 years, releasing significant levels of creosote-related chemicals throughout the immediate region. The Kerr-McGee Corporation spun off its liability for a range of hazardous sites previously under its control to a separate company called Tronox, which subsequently declared bankruptcy in 2009. Andarko Petroleum then purchased Kerr-McGee, but, during bankruptcy proceedings, Tronox filed a complaint against both Andarko and Ker-McGee, alleging fraudulent conveyance of the liabilities. As EPA explains, “At the core of the plaintiffs’ complaints is the allegation that the Defendants fraudulently transferred valuable assets out of Tronox and left Tronox with insufficient funds to pay the billions of […]

(Beyond Pesticides, March 7, 2023) Exposure to glyphosate (Roundup) and its breakdown products is associated with an increased risk of liver and metabolic disorders in children and young adults, according to research published in Environmental Health Perspectives earlier this month. While glyphosate has developed a well-deserved reputation as a carcinogen, research is finding that cancer is one of a myriad of chronic diseases associated with the notorious chemical. As this body of literature grows, growing awareness by the public is increasing pressure on the U.S. Environmental Protection Agency to cancel its allowed uses. Researchers began their investigation concerned about the rise of liver disorders and metabolic syndrome among young people. This trend has been pronounced among populations of color. The worrying increase has led many to consider synthetic chemical exposure as a contributing factor, as lack of diet and exercise is unlikely to account for the entirety of the increase. To better understand these impacts, researchers enrolled existing participants in the CHAMACOS (Center for the Health Assessment of Mothers and Children of Salinas) study, a long running cohort of mothers and their children born between the years 2000 and 2002 in the Salinas Valley of California. Enrolled participants consistent mostly […]

(Beyond Pesticides, March 2, 2023) On February 22, a group of 65 nonprofit organizations (including Beyond Pesticides) filed a citizen petition with the U.S. Environmental Protection Agency (EPA) that asks the agency to close a gaping — and well exploited — regulatory loophole by revoking a 1984 regulation that waived efficacy data requirements in pesticide evaluations. This means that EPA has, for 39 years, registered pesticides without demonstrated proof of efficacy and benefits. The petition is aimed primarily at the widespread use of neonicotinoid insecticides (neonics), which are so harmful to hundreds of species — and to bees, other pollinators, and birds, in particular — that many advocates have insisted they should be banned altogether. Beyond Pesticides has advocated for a neonics ban because of their extensive harms to pollinators, multiple other organisms (including humans), ecosystems, and natural resources. The Center for Food Safety, Pesticide Action Network North America, Center for Biological Diversity, Beyond Pesticides, and other advocates have filed lawsuits in recent years to get EPA to act protectively on neonics and other pesticides. The coalition of groups in the subject case seeks to rein in a plethora of harmful impacts of neonics, given EPA’s overall lack of protective action. (For […]

(Beyond Pesticides, March 2, 2023) Populations experiencing higher levels of environmental pollutant exposure, specifically pesticides, also experience a higher rate of irritable bowel syndrome (IBS), according to a study published in Environmental Toxicology and Pharmacology. IBS is a gastrointestinal disorder that causes abdominal pain or discomfort and changes in bowel behaviors. IBS affects 25 to 45 million individuals in the U.S., mostly female (two-thirds). Additionally, a quarter to half of all gastrointestinal-related visits are for IBS symptoms. Despite the unknown etiology of IBS, ample evidence demonstrates environmental contaminants, like pesticides, negatively affect the gut microbiota, causing a microorganism imbalance and resulting in inflammation associated with IBS. The gut, also known as the “second brain,” shares similar structural and chemical parallels to the brain. The microbiota in the gut plays a crucial role in lifelong digestion, immune and central nervous system regulation, as well as other bodily functions. Although studies show how chemical exposures affect overall human health, a growing body of peer-reviewed scientific literature is now questioning how these toxic chemicals influence gut health and the subsequent occurrence of diseases. The study notes, “These findings may help to understand the relationship between pesticide exposure and IBS; however, more epidemiological and experimental research is needed to understand […]

(Beyond Pesticides, March 1, 2023) Fungicides sprayed on chemically farmed strawberries reduce their flavor quality, according to research published in the Journal of Agricultural and Food Chemistry this week. This explanation is a major insight for frustrated consumers who may remember when the strawberries sold at retail contained deeper, more complex flavors. As the agrichemical industry claims that dangerous pesticides are needed to grow food to feed the world, it is evident these practices health and environmental hazards, but also affect the quality of the food grown. As savvy shoppers and gardeners already know, buying and growing organic addresses this range of issues, improving flavor while protecting wildlife and public health. Scientists developed their study to better understand the mechanisms leading to flavor deterioration by growing strawberry plants in a greenhouse with chemical-intensive practices, including the use of synthetic fertilizers. One group was treated with the fungicide boscalid, another with the fungicide difenconazole, and a control group received no spray. Fruits were sprayed beginning at the green, small fruit stage, a total of two times, and collections from each group were taken at the white, turning, and red fruit stage (zero, three, and seven days after the second pesticide application). […]

(Beyond Pesticides, February 22, 2023) Combining neonicotinoid insecticides with other commonly used pesticides can result in synergistic effects on honey bees, increasing toxicity more than any individual chemical could, according to research published in Scientific Reports earlier this month. The data highlight the grave inadequacy of the U.S. Environmental Protection Agency’s (EPA) process for evaluating pesticide risks. Under current regulations, EPA requires chemical manufacturers to submit data only on singular active ingredients. Yet, pesticide products may be packaged or ‘tank mixed’ with other, equally toxic pesticides without any obligation to determine the toxicity of the material that is actually being applied. Independent research is left to fill in these gaps, and the data increasingly shows that toxicity with pesticide mixtures amounts to a roll of the dice: sometimes combinations are less toxic, sometimes their toxicities are merely additive. But more often than not, pesticide mixtures result in synergistic effects that make the product significantly more toxic than either individual chemical alone. To understand how pesticide combinations are harming pollinators, scientists began with baseline data on the individual toxicity range  that common pesticides pose to honey bee colonies. Research was conducted on honey bees reared in the Stoneville Wildlife Management Area […]

(Beyond Pesticides, February 15, 2023) Glyphosate use in grassland pastures reduces crop yield and impedes climate change mitigation, finds two studies (1,2) published this month from the University of Turku, Finland. While massive public relations campaigns by the agrichemical industry have poured in millions of dollars to convince politicians and the public that pesticides are necessary to ‘feed the world’ and address the climate crisis, the data does not support these claims. “Only in recent years, we have started to realise that intensive agriculture and agrochemical pollution in fact contribute to a reversal of the intended purpose. Soils are polluted with pesticides and at the same time, extreme weather events erode soil nutrients,” says study coauthor Benjamin Fuchs, PhD. Researchers approached their investigation through two separate experiments on the grass Festuca pratensis, an important forage crop grown for grazing animals throughout the world. The first experiment was conducted in an enclosed greenhouse, while the second took place in a field setting. For both experiments, plots were separated between glyphosate-sprayed and unsprayed controls. All plots received three different approaches to cutting the grass: one group that was intensely cut to two inches (5cm), the second group cut to six inches (15cm), […]

(Beyond Pesticides, February 14, 2023) The waterways that flow into the Great Lakes are experiencing year-round pesticide contamination that exceeds benchmarks meant to protect aquatic life, according to research published in Environmental Toxicology and Chemistry by scientists at the U.S. Geological Survey (USGS). “What you use makes it into the water,” study coauthor Sam Oliver, PhD, told the Milwaukee Journal Sentinel. These data buttress growing calls from pesticide reform advocates that new laws are needed to protect the nation’s increasingly threatened waters. USGS scientists conducted their analysis on 16 tributaries that feed into the Great Lakes, including sites that correspond to urban, agricultural, and undeveloped land. Samples were taken at locations closest to the lake the tributary flowed into over a period of roughly one year from October 2015 to September 2016. Each sample was tested for 231 pesticides and their breakdown products. Researchers used aquatic life benchmarks set by the U.S. Environmental Protection Agency (EPA), and created a relative hazard index (RHI) for the study to evaluate whether specific sites should be prioritized for further protections.   Across every sampled tributary, pesticides were found. Accordingly, 96% (190 out of 198) of samples taken contained pesticides or their breakdown products. […]

(Beyond Pesticides, February 10, 2023) The U.S. Environmental Protection Agency (EPA) announced, on February 1, new measures to protect 28 endangered salmon species (including steelhead trout) from the use of four pesticides that threaten them and their critical habitats. Those compounds comprise three herbicides — metolachlor, bromoxynil, and prometryn, and one soil fumigant, 1,3-Dichloropropene. The protections, aimed at salmon populations in Washington, Oregon, and California, are meant to reduce impacts from pesticide runoff and spray drift, and to minimize potential “take.” (Under the Endangered Species Act (ESA), “take” means, essentially, the unintentional harming or killing of an individual of a protected species — in this case, harm or death from exposures to these toxic pesticide compounds.) Beyond Pesticides and other advocates have for years warned that multiple pesticides are threats to Northwest salmon and other species at risk. This EPA announcement is the second of two, recently, that offer slight redress to the agency’s historical failures to act (see more below). Indeed, advocates have engaged in multiple litigation efforts over the years to try to force EPA to take action; EarthJustice in 2001 noted some early instances. As Chemical and Engineering News says pointedly, “Environmental groups, which have been suing […]

(Beyond Pesticides, February 8, 2023) Spraying pesticides around one’s garden negatively impacts local bird populations, according to research published by scientists at the University of Sussex, UK in Science of the Total Environment. Although this reasoning sounds common sense to those versed in the works of Rachel Carson, it underscores the immense importance of carrying on the legacy of her work and continuing to educate the public about the ongoing dangers posed by modern pesticides. As the study authors write, “Overall, our study shows that garden bird abundance and richness is strongly influenced by both extrinsic and intrinsic factors, and suggests that garden management, particularly regarding pesticide use, has a significant effect on bird life.” Researchers collected data by partnering with the British Trust for Ornithology, which conducts annual citizen-science counts of bird populations in UK gardens. Nearly 24,000 residents participate in the survey, which also includes information about the urbanization level surrounding their gardens, and other habitat characteristics. A group of these volunteers were provided with a questionnaire about their pesticide practices between 2020-2021, recording information on how often the pesticides were applied, as well as the pesticide brand name. After removing incomplete or unusable data, 615 individual gardens […]

(Beyond Pesticides, January 31, 2023) Glyphosate exposure induces oxidative stress in the body, a key biomarker known to heighten an individual’s risk of cancer, according to research published in the Journal of the National Cancer Institute by a team of scientists from the National Institutes of Health. The findings, which tracked study participants’ past use of glyphosate and exposure levels through urine, are particularly concerning in light of recent data showing that four out of five (81.6%) U.S. residents have detectable levels of glyphosate in their bodies. Despite these concerning data, evidence of widespread exposure to a carcinogen has so far failed to sway regulators at the U.S. Environmental Protection Agency, necessitating meaningful change by elected officials to reform pesticide regulation. Scientists began with the determination from the International Agency for Research on Cancer (IARC) that there is epidemiological evidence associating glyphosate with blood cancers like non-Hodgkin lymphoma, and strong evidence of carcinogenicity in laboratory animal research brought on by genotoxicity (DNA damage) and oxidative stress. “Oxidative stress occurs when the production of reactive oxygen species (ROS) and other free radicals exceeds the body’s antioxidant defense mechanisms, causing damage to DNA, proteins, and lipids,” the study explains. This process can […]