(Beyond Pesticides, July 15, 2014) More nutritional antioxidants, far fewer toxic pesticides; those are the results of a comprehensive meta-analysis on organic foods published yesterday in the British Journal of Nutrition.  Led by Carlo Leifort, Ph.D, at England’s Newcastle University, the analysis is a scientific rebuttal to a previous Stanford University review published in 2012, which found that there was little difference between the nutritional content of organic food over conventionally grown produce. Both studies found there to be fewer pesticides in organic products. While Stanford University’s review only looked at 200 studies, Dr. Leifert and his team of researchers expanded the scope of their meta-analysis to 343 studies, and also employed more robust analytic tools by analyzing the standardized mean differences of the data from the various studies. It shows very clearly how you grow your food has an impact,” said Dr. Leifert to The New York Times. “If you buy organic fruits and vegetables, you can be sure you have, on average, a higher amount of antioxidants at the same calorie level.” Antioxidants, compounds such as phenolic acids, flavanones, stilbenes, flavones, flavonols and anthocyanin, have been linked to lower risks of cancer and other diseases. For many, news […]

(Beyond Pesticides, July 2, 2014) According to a new study, few obstetricians offer their pregnant  patients advice on how to avoid environmental toxins that might harm their babies, even though doctors recognize that exposure to chemicals like pesticides, bisphenol-A (BPA), and metals can affect  a pregnancy. The study recommends that the medical community improve medical education and training, develop recommendations for prevention and less toxic alternatives, as well as lend support to policy change. The first of its kind study of prenatal counselling, published in the journal  PLOS ONE, Counseling Patients on Preventing Prenatal Environmental Exposures – A Mixed-Methods Study of Obstetricians, found that U.S. obstetricians and gynaecologists feel they lack the medical education and training, and evidence-based guidelines and tools for communicating potential environmental risks to patients. Exposure to environmental toxins, the researchers from the University of California, San Francisco (UCSF) found, is rarely discussed with pregnant patients, even though a national survey shows that 80 percent of physicians agree they should play a part in reducing patients’ exposure to toxins. But, of the 2,500 respondents, only one in five routinely asked  their  patients about these exposures, and just one in 15 said they received training on the harmful […]

(Beyond Pesticides, June 24, 2014) Research from the University of California, Davis CHARGE (Childhood Autism Risks from Genetics and the Environment) study finds that pregnant women who lived within a mile of agricultural fields treated with insecticides are more likely to have their child develop autism. The results of the CHARGE study, published in Environmental Health Perspectives, strengthens calls from public health and environmental groups urging regulators take a precautionary approach to agricultural chemicals and institute increased protections for those who live, work, or go to school near pesticide-treated fields. The CHARGE study looked at pregnant women’s addresses to determine their location relative to fields treated with pesticides. For women who lived less than one mile from crops sprayed with organophosphate insecticides during their pregnancy, researchers found the likelihood of their child being diagnosed with autism increased 60%. Women in the second trimester living near fields treated with chlorpyrifos, a widely used organophosphate insecticide banned for household use in 2001, are 3.3 times more likely to have their children diagnosed with autism. In response to a legal petition, the U.S. Environmental Protection Agency (EPA) in 2012 instituted risk mitigation measures for chlorpyrifos, including reduced application rates and no-spray buffer zones […]

(Beyond Pesticides, June 9, 2014) Triclosan, the antibacterial pesticide found in numerous hand soaps, toothpastes, and other cosmetics, has had a ubiquitous presence on the consumer market for over 30 years. But due to public pressure led by Beyond Pesticides, our allies, and concerned supporters, many manufacturers have been washing their hands of triclosan. Now after years of inaction, the U.S. Food and Drug Administration (FDA) is going to require data to support triclosan’s claims of being “safe and effective.” The time is now to let the agency know that triclosan is NOT safe or effective for human and environmental health. Raise your voice with a unique public comment to FDA! Use the sample letter below for guidance. Rising Evidence Against Safety Beyond Pesticides has generated extensive documentation  of the potential human and environmental health effects of triclosan and its cousin triclocarban. Studies show that triclosan can interfere with thyroid and estrogen hormones, and may promote the progression of cancer cells. This is alarming given that the CDC has found that 75% of the U.S. population contain triclosan in their bodies, even in breast milk, and at levels that are rising. Triclosan is an endocrine disruptor and has been shown […]

(Beyond Pesticides, June 5, 2014) Environmental advocacy groups filed an Administration Objection and a court appeal last week in order to challenge the Environmental Protection Agency’s (EPA) refusal to quickly correct errors in pesticide registrations and immediately implement measures to protect children from exposure to dangerous pesticides that drift from fields during and after application. EPA’s continued refusal to protect children’s health from pesticide drift is being criticized by numerous environmental, health, and farmworker advocacy groups. The groups, which include  United Farmworkers, Pineros y Campesinos Unidos del Noroeste, Pesticide Action Network of North America, Sea Mar Community Health Centers, California Rural Legal Assistance Foundation, Physicians for Social Responsibility, and Farm Labor Organizing Committee, originally filed a petition back in 2009 titled “Pesticides in the Air””Kids at Risk: Petition to EPA to Protect Children from Pesticide Drift (2009).” The petition asked that the agency properly comply with an existing law that requires EPA to protect children’s health from exposure to pesticides that drift from fields and orchards. After a more than four-year wait and a court appeal, EPA finally provided a response last March. These groups object to EPA’s recent response to their 2009 petition on the basis of two issues, […]

(Beyond Pesticides, March 21, 2014) Banned pesticides and flame retardants may be the cause of higher autistic behaviors for children who were exposed in utero, according to new research published last week in the journal Environmental Health Perspectives. Previous research has demonstrated that organochlorine chemicals are linked to learning problems, such as attention-deficit hyperactivity disorder (ADHD), especially in boys. This research is one of the first studies to evaluate their contribution to autistic behaviors. According to the study, Gestational Exposure to Endocrine-Disrupting Chemicals and Reciprocal Social, Repetitive, and Stereotypic Behaviors in 4- and 5-Year Old Children, children who were exposed to higher levels of brominated flame retardant PBDE-28 and trans-nonachlor, a component of the banned pesticide chlordane, scored higher in terms of autistic behavioral patterns as ranked by their mothers. In the study, researchers conducted a case-cohort study recruiting 175 pregnant women from seven prenatal clinics within the greater Cincinnati, Ohio region who provided urine and blood samples during pregnancy to measure the concentration of endocrine disrupting chemicals. On average, pregnant women had 44 suspected hormone disrupting chemicals. Five years later, when children had turned four or five, mothers were asked to rank their children’s behavior based on a series […]

(Beyond Pesticides, March 13, 2014) Part deux of a 2012 study finding that sperm counts in French men had decreased 30% over the past 16 years came to a second startling conclusion in a 2014 analysis: the cause for those dramatic decreases may be pesticides. 2012 Sperm-Count Study Published in the scientific journal Human Reproduction, the landmark 2012 study showed an alarming 30 percent decrease in sperm counts across France between 1989 and 2005. Because the data for the 2012 study were drawn from Fivnat ””a French assisted reproduction technology database”” researches made sure to limit analysis to 26,600 sperm samples from otherwise virile 35-year-old men whose partners’ fallopian tubes were either blocked or missing. This control was added to ensure that the each couple’s infertility was due to these latter problems and not a problem with the man’s sperm. Broken down, the 2012 studies identified a 1.9 percent continued annual dip in sperm concentration and also found that there was a significant 33.4% decrease in the percentage of normally formed sperm over the entire 16-year period. At the time of release, the 2012 study’s authors wrote: “To our knowledge, it is the first study concluding a severe and general […]

(Beyond Pesticides, December 20, 2013) The European Food Safety Authority (EFSA) announced on Tuesday that pesticides linked to honey bee deaths worldwide may also damage human nervous systems ””in particular the brain, and recommended that the European Commission lower the guidance levels of acceptable exposure until more research is conducted. This new determination heightens the call to ban the use of these toxic chemicals in the U.S., following the lead of the European Union (EU). EFSA found that two commonly used chemicals “may adversely affect the development of neurons and brain structure associated with functions such as learning and memory” particularly of children. The recommendation focuses on two chemicals ””acetamiprid and imidacloprid”” in a relatively new class of insecticide called neonicotinoids. Three chemicals in this class were recently placed under a two-year ban in the European Union (EU) for uses on flowering crops known to attract honey bees. The move stems from a recent review of research on rats which found, “Neonicotinoids may adversely affect human health, especially the developing brain.” Researchers who exposed newborn rats to one of these chemicals ””imidacloprid”” found they suffered brain shrinkage, fewer nerve signals controlling movement, and weight loss. Another study on rats found […]

(Beyond Pesticides, November 7, 2013) A study released this week established a strong connection between endometriosis and exposure to two dangerous pesticides: lindane and mirex. While the results are not surprising given past connections between these pesticides and their endocrine-disrupting effects, this new study, Organochlorine Pesticides and Risk of Endometriosis: Findings from a Population-Based Case-Control Study, is one of the first to examine the association between organochlorine pesticides (OCPs) and endometriosis, one of the most common gynecological diseases, in women in the general population. The study’s authors, Kristen Upson, Ph.D. et al,  explained to Environmental Health Perspectives, “Our study suggests that exposure from extensive past use of environmentally persistent OCPs in the United States, or present use in other countries may impact the health of the current generation of reproductive-age women with regard to a hormonally-mediated disease.” In conducting the study, researchers selected a group of women with surgically-confirmed cases of endometriosis from the greater Pacific Northwest area. This group of women was then divided into four groups, based on the level of pesticide in each woman’s blood. Women in the second-highest exposure group for beta-hexacyclochlorohexane (beta-HCH), a byproduct of lindane, had a 70 percent greater risk of endometriosis than […]

(Beyond Pesticides, November 1, 2013) Insecticides commonly used in homes and schools are associated with behavioral problems in children, according to a recent study by Canadian researchers. The study investigates exposure to pyrethroid pesticides, used in more than 3,500 products, including flea and tick controls, cockroach sprays, and head lice controls. The study, Urinary metabolites of organophosphates and pyrethroid pesticides and behavioral problems in Canadian children, published in the journal Environmental Health Perspectives, raises serious concerns about the impact of pyrethroids, which are increasingly used as a replacement for organophosphates. This study uses data from the Canadian Health Measures Survey (2007-2009), a nationally representative survey, so researchers are able to apply these findings to the entire population of Canadian children. In a previous study among U.S. children, researchers at the National Health and Nutrition Examination Survey (NHANES) examined the metabolites of pyrethroids in children below the age of six. Similarly, they found pyrethroid insecticides in more than 70 percent of the samples, concluding that children had significantly higher metabolite concentrations than those of adolescents. Together these studies demonstrate that exposure is widespread, with real impacts to human health. In the recent study, researchers analyzed organophosphate and pyrethroid metabolites in the […]

(Beyond Pesticides, May 9, 2013) A review of the scientific literature of the toxic effects of glyphosate, one of the most popular weed killers in the U.S. and the active ingredient in Roundup, links the herbicide  to a wide range of diseases and suggests  that more research is needed. The review, conducted by a scientist at Massachusetts Institute of Technology (MIT), looks at the mechanisms through which the adverse effects may be happening and points to  the chemical’s inhibition of cytochrome P450 (CYP) enzymes, which plays the crucial role of detoxifying xenobiotics. Thus, glyphosate can enhance the negative effects of other environmental toxicants on the body. Authors argue that this has been a critically overlooked component in research on glyphosates’ toxicity to mammals. We “have hit upon something very important that needs to be taken seriously and further investigated,” Stephanie Seneff, PhD, lead author and research scientist at MIT, told Reuters. Not surprisingly, Monsanto, the developer of Roundup, the leading product containing glyphosate, has attempted to discredit the study, claiming that its product has a long track record of being safe – read Another Bogus “Study.” However, Beyond Pesticides has assembled  extensive documentation on the human health and environmental risks […]

(Beyond Pesticides, April 26, 2013) Female agricultural workers experience the same hardships as their male counterparts, but have additional responsibilities and danger at home and in the field, according to a report released by the Association of Farmworker Opportunity Programs (AFOP). While women make up only 22 percent of agricultural labor in the U.S., AFOP makes a strong argument that women face disproportionate burdens, while at the same time earning less for their labor: On average they earn  just over $11,000 per year compared to male agricultural workers who earn $16,000. Through hundreds of interviews and focus groups of female farmworkers in California and Florida, AFOP revealed some of the most dangerous  conditions associated with farm work, among the worst being pesticide exposure. Carmela, a farmworker from Florida, indicated in the AFOP report that, “More than anything else, we have problems with pesticides. Sometimes they put us to work right after they’ve sprayed the pesticides. And this is bad for us because when we go in the field and start working with the plants, it gets in our eyes. It makes your head hurt too.” According to the EPA’s “Pesticide Industry Sales and Usage: 2000 and 2001 Market Estimates,” female […]

(Beyond Pesticides, April 24, 2013) Using the aquatic species Daphnia, commonly referred to as “water fleas,” scientists at North Carolina State University (NC State) determined that exposure to the pesticide pyriproxyfen impacted multiple generations, ultimately resulting in more male offspring, and causing reproductive problems in female offspring. Lead author Gerald LeBlanc, PhD, notes, “This work supports the hypothesis that exposure to some environmental chemicals during sensitive periods of development can cause significant health problems for those organisms later in life —and affect their offspring and, possibly, their offspring’s offspring.” The study, published in the journal PLoS One, provides the scientific community with new information on how organisms respond to the environmental signals resulting from pesticide exposure. Environmental cues normally determine whether the Daphina offspring will be male or female, according to the researchers. This study is part of an investigation to understand the mechanisms involved with these environmental cues. The NC State team had previously identified the hormone methyl farnesoate (Mf) as an important factor in determining the sex of the organisms at the embryotic stage. The scientists exposed Daphnia to varying levels of the pesticide pyriproxyfen, an insecticide that mimics the Mf hormone. The exposure resulted in Daphnia producing […]

(Beyond Pesticides, December 10, 2012) Long-term low-level exposure to organophosphate pesticides produces lasting damage to neurological and cognitive functions, according to researchers at University College London (UCL). This research pulls data from 14 studies over the past 20 years, including more than 1,600 participants, in order to provide a quantitative analysis of the current literature on these dangerous chemicals. Lead author of the study, Sarah Mackenzie Ross, Ph.D., notes, “This is the first time anyone has analyzed the literature concerning the neurotoxicity of organophosphate pesticides, using the statistical technique of meta-analysis.” UCL’s systematic review, published in the journal Critical Reviews in Toxicology, comes to an unsettling conclusion about the hazards of constant low-level occupational exposure to organophosphates. The study notes, “The majority of well designed studies found a significant association between low-level exposure to [organophosphates] and impaired neurobehavioral function which is consistent, small to moderate in magnitude and concerned primarily with cognitive functions such as psychomotor speed, executive function, visuospatial ability, working and visual memory.” In other words, low-level exposure had significant detrimental effect on working memory and information processing. The researchers are hopeful that the results of their analysis will be used to inform governments performing reviews on the […]

(Beyond Pesticides, August 10, 2012) A new study is the first to find a difference between how boys and girls respond to prenatal exposure to the insecticide chlorpyrifos. Researchers at the Columbia Center for Children’s Environmental Health (CCCEH) at the Mailman School of Public Health found that, at age 7, boys had greater difficulty with working memory, a key component of IQ, than girls with similar exposures. On the plus side, having nurturing parents improved working memory, especially in boys, although it did not lessen the negative cognitive effects of exposure to the chemical. Results are published online in the journal Neurotoxicology and Teratology. In 2011, research led by Virginia Rauh, ScD, Co-Deputy Director of CCCEH, established a connection between prenatal exposure to chlorpyrifos and deficits in working memory and IQ at age 7. Earlier this year, a follow-up study showed evidence in MRI scans that even low to moderate levels of exposure during pregnancy may lead to long-term, potentially irreversible changes in the brain. The latest study, led by Megan Horton, PhD, explored the impact of sex differences and the home environment on these health outcomes. Dr. Horton and colleagues looked at a subset of 335 mother-child pairs enrolled […]

(Beyond Pesticides, August 1, 2012) New research is adding to the evidence that some pesticides and industrial chemicals may increase women’s risk of uterine and ovarian diseases, such as endometriosis. The research supports the decades old theory that hormone-mimicking chemicals impact human reproductive systems. Scientists have long suspected a link between estrogen-mimicking pollutants and gynecological diseases. According to Environmental Health News, research investigating a link between hormone-disrupting chemicals in the environment and gynecological diseases has had mixed results. But a new study, “Persistent Lipophilic Environmental Chemicals and Endometriosis: The ENDO Study,” from researchers at the National Institutes of Health and others, found that two groups of women in the Salt Lake City and San Francisco areas — one group with pelvic pain and the other with no symptoms — were more likely to be diagnosed with endometriosis if they had high blood levels of the estrogen-like pesticide hexachlorocyclohexane (HCH) than women with low levels. HCH, a persistent organic pollutant (POP), and a byproduct of the production of the insecticide lindane (head lice treatments), has been banned as a crop pesticide in the United States but it persists in the environment and remains in some food supplies. Endometriosis is a female […]

(Beyond Pesticides, July 5, 2012) After a 2006 cancellation of uses due to unreasonable risks to farmworker health and the environment, and a 6-year phase out scheduled to conclude this September, the U.S. Environmental Protection Agency (EPA) is conducting a risk-benefit analysis to make a determination whether to keep in place or amend the cancellation order for the organophosphate azinphos-methyl (AZM), citing new information on the economic costs of using alternatives. In 2001, EPA found that insecticides azinphos-methyl (AZM) posed unacceptable risks to farmworkers and announced that 28 crop uses were being canceled, seven crop uses were to be phased-out over four years, and eight crop uses were to be allowed to continue under a “time-limited” registration for another four years. Farmworker advocates challenged that decision in federal court citing that EPA failed to take into account the costs of poisoning workers, exposing children, and polluting rivers and streams. A settlement agreement effectively stayed the legal challenge pending EPA’s reconsideration of the “time limited” uses of AZM. In November 2006, EPA decided that AZM poses unreasonable adverse effects and issued a final decision to cancel AZM, but allowed continued use on some fruit crops (apples, cherries, pears) for six more […]

(Beyond Pesticides, June 15, 2012) Researchers at the Duke University School of Medicine have developed a laboratory screening system for detecting neurotoxic chemicals and successfully tested it on more than 1,400 potential toxicants. The study confirms the high toxic activity of the chemical piperonyl butoxide (PBO), a chemical “synergist” used to increase the potency of more than 700 insecticides, including synthetic pyrethroids widely used in mosquito and community spray programs and for home use. The study, entitled “The Insecticide Synergist Piperonyl Butoxide Inhibits Hedgehog Signaling: Assessing Chemical Risks,” was published in the May 2012 edition of the journal Toxicological Sciences. The testing shows that PBO disrupts a biological signaling system that is “critical in neurological development,” the researchers reported in the abstract of their paper. The study finds that the disruption of this critical pathway “may be the molecular basis for profound developmental defects in children exposed in utero to PBO.” Piperonyl butoxide is not itself classified as a pesticide, but companies combine it with insecticides to increase their potency. PBO came into widespread use when the U.S. Environmental Protection Agency (EPA) phased out chlorpyrifos and other organophosphate pesticides nearly a decade ago after determining that they posed a risk […]

(Beyond Pesticides, May 2, 1012) New research published online at the Proceedings of the National Academy of Sciences reports that babies exposed in the womb to a commonly used insecticide have brain abnormalities after birth. The insecticide, chlorpyrifos (used in agriculture, mosquito control, and golf course management) , is well documented as inducing neurodevelopmental abnormalities in infants exposed in their mother’s womb, including ADHD, cognitive deficits, and serious learning, behavioral or emotional disorders. Entitled, “Brain anomalies in children exposed prenatally to a common organophosphate pesticide,” the study investigated associations between chlorpyrifos exposure and brain morphology using magnetic resonance imaging in 40 New York City children. It found significant associations of prenatal exposure, at standard use levels, with structural changes in the developing human brain, including enlargement of superior temporal, posterior middle temporal, and enlarged superior frontal gyrus, gyrus rectus, cuneus, and precuneus along the mesial wall of the right hemisphere. These areas of the brain impacted are related to attention, language, reward systems, emotions and control may be affected by the chemical. Twenty high-exposure children (upper third of chlorpyrifos concentrations in umbilical cord blood) were compared with 20 low-exposure children. The children, ages 6-11 years, considered to have a high […]

(Beyond Pesticides, April 9, 2012) A new study finds that exposure of pregnant women to organophosphate (OP) pesticides —a widely used class of pesticides in North American agriculture— may affect both length of pregnancy and birth weight. Environmental Health Perspectives published the paper, “Associations of Prenatal Exposure to Organophosphate Pesticide Metabolites,” last Thursday, April 5, 2012. The study, by a Simon Fraser University researcher, finds that the population of 306 women in Cincinnati, Ohio, is representative of the type of exposures most North American women and their children experience. Although the use of OPs in Canada and the U.S. has declined in recent years, exposures remain widespread, and these findings add to growing evidence about the harmful effects of low-level exposures to environmental toxicants. The researchers collected urine from each of the women in Cincinnati twice during their pregnancies for organophosphate metabolites as well as other factors that could influence the fetus’ health, including exposure to second hand smoke, race, and poverty. Women with higher levels of organophosphates were found to have pregnancies that were three to four days shorter and babies that were about â…“ pound lighter on average than women with lower levels of pesticides. “For an individual […]

(Beyond Pesticides, December 9, 2011) A recent study published in the journal NeuroToxicology has found a positive link between exposure to the pesticide propoxur and poor motor development in infants. At the age of two, children exposed to propoxur in the womb experience poor development of motor skills, according to a test of mental development. The study joins numerous others that consistently show birth defects and developmental problems when fetuses and infants are exposed to pesticides. The study, undertaken by researchers at Wayne State University in Michigan, the University of the Philippines, and Davao Regional Hospital in the Philippines, is entitled “Fetal exposure to propoxur and abnormal child neurodevelopment at 2 years of age.” It examines levels of exposure to multiple pesticides in pregnant women living in areas of high pesticide use in the Philippines. Pesticide exposure was monitored by measuring the pesticide content of hair and blood for both mothers and children. The researchers then compare these exposure levels to adverse outcomes regarding the health of the infants once they were born. To accomplish this, the team used a method called path analysis modeling in order to determine what effects the pesticides might have on fetal development. The striking […]

(Beyond Pesticides, November 29, 2011) New research shows that women who drink water containing the widely used herbicide atrazine may be more likely to have irregular menstrual cycles and low estrogen levels, even at concentrations far below federal drinking water standards considered safe by the U.S. Environmental Protection Agency (EPA). Researchers compared women living in Illinois farm towns where atrazine is used regularly to women living in Vermont where the herbicide is used sparingly, and found that the women in Illinois were almost five times more likely to report irregular menstrual cycles, including more than six weeks between periods. Consumption of over two cups of unfiltered Illinois water daily was associated with increased risk of irregular periods. The study, entitled “Menstrual cycle characteristics and reproductive hormone levels in women exposed to atrazine in drinking water,” was published in the journal Environmental Research earlier this month, and is based on municipal tap water tested between July and September of 2005. In the study, participants maintained menstrual cycle diaries, answered a questionnaire, and provided daily urine samples for analyses of luteinizing hormone and estradiol and progesterone metabolites. To measure exposure, analysts looked at the state of residence, concentrations of atrazine and chlorotriazine […]

(Beyond Pesticides, July 25, 2011) Exposure to certain pesticides and polycyclic aromatic hydrocarbons (PAHs) in the womb has been linked to neural tube defects, which lead to conditions such as spina bifida, according to researchers at Peking University in China. The study finds elevated levels of the organochlorine pesticides DDT, alpha-hexachlorocyclohexane (a lindane contaminant) and endosulfan, as well as PAHs in the placentas of women who had babies or aborted fetuses with such birth defects. The study, “Association of selected persistent organic pollutants in the placenta with the risk of neural tube defects,” was published July 8, 2011 in the online edition of the Proceedings of the National Academy of Sciences. While most organochlorine pesticides are banned or restricted, they still continue to cause problems decades after their widespread use has ended. This study reinforces the need for a more precautionary approach to regulating pesticides and industrial chemicals. Once released into the environment, many chemicals can affect health for generations, either through persistence or genetic means. PAHs are a group of over 100 different chemicals that are formed during the incomplete burning of coal, oil and gas, garbage, or other organic substances like tobacco or charbroiled meat. PAHs are usually […]