(Beyond Pesticides, April 8, 2021) Pesticide use threatens aquatic and terrestrial invertebrates and plants more than ever, despite declining chemical use and implementation of genetically engineered (GE) crops in the U.S., according to a University Koblenz-Landau, Germany study. Since the publication of Rachel Carson’s Silent Spring (1962), many environmental agencies have banned the use of pesticides like organochlorines, organophosphates, and carbamates for their devastating toxic—sometimes lethal—effects, particularly on vertebrates, including humans. However, this ban created a pathway for a new generation of pesticides (e.g., neonicotinoids, pyrethroids) to take hold. Although these pesticides are more target-specific, requiring lower chemical concentrations for effectiveness, they have over double the toxic effects on invertebrates, like pollinators.  Invertebrates and plants are vital for ecosystem function, offering various services, from decomposition to supporting the food web. Furthermore, invertebrates and plants can act as indicator species (bioindicators) that scientists can observe for the presence and impact of environmental changes and stressors. Therefore, reductions in invertebrate and plant life have implications for ecosystem health that can put human well-being at risk. Study lead author Ralf Schulz, PH.D., notes, “[This study] challenge[s] the claims of decreasing environmental impact of chemical pesticides in both conventional and GM [genetically modified or genetically engineered (GE)] crops and […]

(Beyond Pesticides, March 29, 2021) New data on the hazards of neonicotinoid insecticides calls for urgent regulatory action. The same pesticides that are linked to the worldwide decline of insect pollinators also present significant risks to their avian counterparts, hummingbirds. Widely known for their nectar-fueled hovering flight powered by wings beating up to 80 times per second, hummingbirds display unique reactions to toxic pesticides. Research by scientists at the University of Toronto finds that hummingbirds exposed to systemic neonicotinoid insecticides for even a short period of time can disrupt the high-powered metabolism of this important and charismatic animal. Tell EPA and Congress to save the hummingbirds by suspending use of neonicotinoid insecticides and supporting the transition to organic practices. While hovering, a hummingbird consumes calories faster than any other bird or mammal. That’s why the finding that exposure to the neonicotinoid insecticide imidacloprid slows metabolism up to 25% is so disturbing. Systemic pesticides like imidacloprid and other neonics are transported throughout the plant, including nectar. Findings on the danger neonicotinoids pose to hummingbirds decades after the chemicals were first permitted to be used in the environment, and by independent scientists, not regulatory agencies, is indicative of a regulatory approach that fails […]

(Beyond Pesticides, March 24, 2021) The worst predictions of scientists and advocates are playing out in the fields of eastern Kenya, as chemical-intensive farming there threatens the future of food production. According to Radio France Internationale (RFI), Kenyan farmers have resorted to pollinating their crops by hand after pesticide use killed off most of the pollinators they rely on. “We are mostly affected by pesticides because they have killed most pollinators which pollinate our crops—this has affected our food production compared to previous years,” said Joseph Mbithi, a farmer in Mbakoni village, Makueni County, Kenya to RFI. Crop yields in the region have tapered off over the last two years, and farmers like Mr. Mbithi are pointing to pesticide use as the cause, citing past reliance on the herbicide Roundup (glyphosate) and the organophosphate insecticide malathion. “Pollinators such as bees and butterflies are not around due to chemicals which we spray in our farms,” he told RFI.   As a result, farmers are using toothbrushes and sponges as a substitute for the buzzing work of local pollinators. And it’s more complicated than one may think. ‘’The flowers are different in shape and are different in sizes. The male one is […]

(Beyond Pesticides, March 19, 2021) As reported by VTDigger, Vermont’s Endangered Species Committee recently took action to uphold the state’s endangered species law. The committee announced that a mosquito control program in the Champlain Valley, which uses the toxic pesticides malathion and permethrin, is threatening five species of endangered bats — all of which are on Vermont’s list of threatened and endangered species. The committee voted unanimously to recommend to the state Secretary of the Agency of Natural Resources that the spraying program in the Brandon, Leicester, Salisbury, Goshen, Pittsford Insect Control District be allowed only via special permit. Learn about safer mosquito management and insect-borne diseases at Beyond Pesticides website pages. The bats inhabit the Insect Control District’s five towns, which are host to important feeding habitat for these creatures, as well as maternal roosting colonies where baby bats are born and raised during the months when the pesticides are typically sprayed. In addition, the nighttime spraying of these compounds along 190 miles of road in these communities hangs in the air for hours, putting nocturnally active bats — who fly through the toxic mist or consume insects contaminated with the chemicals — at risk. Mason Overstreet of Vermont […]

(Beyond Pesticides, March 2, 2021) Populations of solitary ground nesting bees decline after exposure to neonicotinoid insecticides, according to a study published in Scientific Reports late last month. In addition to ground-nesting bees, neonicotinoids have been shown to harm butterflies, hummingbirds, songbirds, aquatic species and mammals, including humans. As independent science continues to look beyond the effects of these systemic chemicals on honey and bumblebees, advocates maintain that it has become increasingly clear that the high hazards presented by neonicotinoids necessitate their complete elimination. “Farmers need to protect their crops from pests, but they also absolutely need to protect pollinators from the unintended effects of pesticides,” said study coauthor Susan Willis Chan, PhD. “The data on this particular [neonicotinoid] product are so clear that there’s really no question about what has to happen. We have to find something else.” Researchers focused their effort investigating how various systemic pesticides effect the hoary squash bee (Eucera pruinosa), a ground nesting bee found throughout North America that feeds entirely on pollen from cucurbits (including squash, cucumber, pumpkin, gourds, etc). The hoary squash bee provides essential pollinator services for these crops throughout the U.S. and Canada. Neonicotinoids and other systemic insecticides are often applied […]

(Beyond Pesticides, February 23, 2021) The same pesticides implicated in the worldwide decline of insect pollinators also present significant risks to their avian counterparts, hummingbirds. Well known for their nectar-fueled hovering flight powered by wings beating over 50 times per second, hummingbirds display unique reactions to toxic pesticides. Research by scientists at the University of Toronto finds that hummingbirds exposed to systemic neonicotinoid insecticides for even a short period of time can disrupt the high-powered metabolism of this important and charismatic animal. Scientists began their experiment by trapping 23 wild ruby-throated hummingbirds and housing them in an animal care facility. One group of birds acted as a control and received no pesticide exposure, while the rest were assigned either low, middle, or high exposure (1 part per million [ppm], 2ppm, and 2.5ppm, respectively) to the neonicotinoid imidacloprid. Scientists determined these amounts based upon probable nectar contamination in the real world. The pesticide was incorporated into the sugar solution provided to the birds over the course of three days. Within two hours of exposure to the pesticides, hummingbird metabolism dropped significantly. While the control group increased energy expenditure between 1% to 7%, the low exposed group displayed a 6% average decline, […]

(Beyond Pesticides, February 22, 2021) Congressional Rep. Joe Neguse, Rep. Alan Lowenthal and Chair of the Natural Resources Subcommittee on Water, Oceans and Wildlife Rep. Jared Huffman have reintroduced their resolution (H.Res. 69: Expressing the need for the Federal Government to establish a national biodiversity strategy for protecting biodiversity for current and future) to create a national biodiversity strategy. Everywhere we turn, we see signs of ecological collapse—wildfires, the insect apocalypse, crashing populations of marine organisms, more and more species at risk, rising global temperatures, unusual weather patterns, horrific storms, and pandemics. Never was a holistic strategy on biodiversity more urgent. Tell your U.S. Representative to cosponsor Rep. Neguse’s National Biodiversity Strategy Resolution, H.Res. 69. The resolution calls for a natio. 69.nal commitment to addressing the biodiversity crisis by establishing a strategy to be developed through an interagency process announced by the president in an Executive Order. The strategy process will encourage agencies to identify and pursue a full range of actions within existing laws and policies and encourage consideration of new ones. It would also promote accountability and progress in addressing the biodiversity crisis through a new quadrennial assessment. “The decline of biodiversity presents a direct threat to the security, […]

(Beyond Pesticides, February 8, 2021) Immediately following his inauguration, President Biden issued an Executive Order (EO) directing the heads of all executive departments and agencies to produce recommendations for improving and modernizing regulatory review, with a goal of promoting public health and safety, economic growth, social welfare, racial justice, environmental stewardship, human dignity, equity, and the interests of future generations. This Executive Order, if effective, will  reverse the historical trend of status-quo regulatory reviews required by the White House Office of Management and Budget (OMB) that typically support vested economic interests of polluters (e.g., petroleum-based pesticide and fertilizer manufacturers). Instead, the President’s EO, Modernizing Regulatory Review, sets the stage for the adoption of agency policy across government to seriously and with urgency confront the climate crisis, biodiversity collapse, and disproportionate harm to people of color communities (environmental racism). Key agencies that can have a systemic effect in meeting these existential challenges are the Environmental Protection Agency (EPA), Department of Interior (DOI), Department of Agriculture (USDA), and Department of Labor/Occupational Safety and Health Administration (DOL/OSHA). But the EO will remain words on a page unless we all across the country exercise our voice and advocate for the changes necessary to end […]

(Beyond Pesticides, January 27, 2021) Lowest ever recorded! That’s the result of a yearly winter monarch count along the California coast, overseen each year by the conservation group Xerces Society. In 2020, citizen scientists counted only 2,000 butterflies. The findings indicate that many on the planet today are likely to experience, within their lifetimes, a world where western monarchs are extinct—unless the federal government acts now. Western monarchs migrate from the Pacific Northwest to overwintering grounds along the California coast, where they remain in relatively stationary clusters that are easy to count.  In the 1980s, roughly 10 million monarchs overwintered along the coast. By the 1990s, that number fell into the low single digits, roughly 1.2 million. Five years ago counts were at roughly 300,000. By 2019, numbers crashed below 30,000. This year’s count saw no monarchs at iconic overwintering sites like Pacific Grove. Other locations, like Pismo State Beach Monarch Butterfly Grove and National Bridges State Park saw only a few hundred. “These sites normally host thousands of butterflies, and their absence this year was heartbreaking for volunteers and visitors flocking to these locales hoping to catch a glimpse of the awe-inspiring clusters of monarch butterflies,” said Sarina Jepsen, […]

(Beyond Pesticides, January 13, 2021) An ethanol processing plant located in the small village of Mead, Nebraska has been using seeds coated in bee-toxic chemicals as part of its production process, according to reporting published in The Guardian earlier this week. The plant, owned by a company called AltEn, may be the only plant in the U.S. producing biofuels with toxic seeds. There is a reason for that, and Mead residents are experiencing the adverse effects of EPA not regulating treated seeds. The prevalence of the use of seed coatings in chemical agriculture has increased over the last several decades, as the pesticide industry works to increase product sales by exploiting a loophole in federal pesticide law. Under FIFRA (the Federal Insecticide Fungicide and Rodenticide Act), a clause known as the “treated article exemption” permits seeds to be coated with highly toxic pesticides without any requirement for the U.S. Environmental Protection Agency (EPA) to assess environmental or public health effects of their use. This allows hazardous pesticides (primarily insecticides and fungicides) to be used indiscriminately with no effective oversight. Research finds that over 150 million acres of farmland are planted with toxic seeds, including nearly four tons of bee-killing neonicotinoids […]

(Beyond Pesticides, November 11, 2020) Neonicotinoid insecticides inhibit honey bee sleep cycles, leading to stress and population declines, according to research from Vanderbilt University, published in Scientific Reports. Although there is already ample evidence of the dangers these systemic insecticides pose to pollinators – as evidenced by recent bans in the European Union and Canada – this new line of investigation add further detail to the ongoing crisis in the pollinator world. “I was thinking about honey bee disappearances and it clicked—if pesticides are killing bees indirectly but we don’t know exactly how, maybe it’s because they’re getting physically lost,” said study coauthor Michael Tackenberg, PhD.  Scientists conducted the experiment using honey bees located on Vanderbilt’s campus, which does not use neonicotinoid insecticides. After returning from pollen collection, forager bees were captured at their hive entrance and moved into monitoring tubes, which were subsequently transferred to the lab. In the lab, scientists were able to control light and dark cycles, and exposed bees to levels neonicotinoids they would likely experience if foraging on contaminated flowers. Foraging bees were first exposed to light/dark at 12/12 cycles, followed by four days of complete darkness, at which time some bees were provided neonics, […]

(Beyond Pesticides, October 29, 2020) Natural areas around farmlands play an important role in managing pest outbreaks and therefore reducing insecticide use, a new study published in the journal Ecology Letters finds. While industrial agriculture puts pressure on farmers to grow single crops on ever larger farms to achieve economies of scale, these monoculture landscapes have significant downsides for public health and the environment. “Overall, our results suggest that simplified landscapes increase vineyard pest outbreaks and escalate insecticide spray frequencies,” said lead author Daniel Paredes, PhD, to the Daily Democrat. “In contrast, vineyards surrounded by more productive habitats and more shrubland area are less likely to apply insecticides.” To investigate the effect of nearby landscapes on farm pest pressure, the team of University of California, Davis scientists used a database created by the government of Spain. For 13 years, the government monitored 400 Spanish vineyards for the presence of the European Grapevine Moth. The moth is a notorious vineyard pest (discovered in California vineyards in 2009), laying three generations of eggs on grapes. In the first generation, the moth larvae will web and feed on flowers. In the second and third, they feed on berries, damaging harvests. Scientists developed a […]

(Beyond Pesticides, October 20, 2020) The additive stress of pesticide exposure and food scarcity leads to significant declines in wild pollinator populations, according to research published by scientists at University of California, Davis. Although it is well known that insect and pollinators populations are at risk from multiple stressors related to industrial agriculture, comprehensive evaluations are a challenging scientific undertaking. “Just like humans, bees don’t face one single stress or threat,” said lead author Clara Stuligross, a PhD. candidate in ecology at UC Davis. “Understanding how multiple stressors interplay is really important, especially for bee populations in agricultural systems, where wild bees are commonly exposed to pesticides and food can be scarce.” To better understand the interplay between these two stressors, researchers designed a field study. Mason bee pollinators were provided cages to nest in, and each stressor was separated out. One set of bees were provided high levels of food availability, while another received scant floral resources. Certain cages within each food level were treated with the product Admire Pro, a Bayer Cropscience insecticide containing the neonicotinoid imidacloprid. Scientists found significant impacts on the factors that deal with mason bees’ reproductive success. This includes the likelihood that a female […]

(Beyond Pesticides, October 9, 2020) A new study demonstrates that emerging “novel” insecticides can cause significant, sublethal harm to beneficial organisms at typical “real life” exposure levels. As neonicotinoid insecticides have come under fire for their terrible impacts on a broad variety of beneficial insects — including their major contributions to the decline of critical pollinators — more such “novel” pesticides are being brought to market in response. The study results, the co-authors say, “confirm that bans on neonicotinoid use will only protect beneficial insects if paired with significant changes to the agrochemical regulatory process. A failure to modify the regulatory process will result in a continued decline of beneficial insects and the ecosystem services on which global food production relies.” Beyond Pesticides would add that the study outcome points, yet again, to the grave recklessness of the pervasive “addiction” to chemical pesticides in agriculture. The solution to this chemical morass is known, doable, and scalable: a transition to organic, regenerative agricultural practices that get everyone off the “toxic treadmill.” Neonicotinoid pesticides (neonics) are the class of chemical pesticides most commonly used worldwide, both on crops and as seed treatments. They are systemic, meaning they infiltrate all tissues of a […]

(Beyond Pesticides, September 30, 2020) Low doses of neonicotinoid (neonic) insecticides are known to disrupt insect learning and behavior, but new science is providing a better understanding of how these effects manifest at a cellular level. Published in the Proceedings of the National Academy of Sciences, this study finds that the neonic imidacloprid binds to brain receptors, triggering oxidative stress, reducing energy levels, and causing neurodegeneration. “Although many studies have shown that low doses of insecticides can affect insect behavior, they have not uncovered whether insecticides trigger changes at the cellular and molecular levels,” said lead author Felipe Martelli, PhD, of Monash University in Melbourne, Australia. “The goal of this work was to have a better understanding of the effects of low doses of the common insecticide imidacloprid at the cellular, physiological and behavioral levels.” Researchers used the fruit fly Drosophilia melanogaster, a common experimental organism, as it contains a number of nicotinic acetylchloline receptors, the primary site of action for imidaclorpid. The neonic binds to these receptors, which regulate a number of physiological processes, such muscle contraction. Binding closes these channels, leading to the range of harm researchers observed through their study. Larval fuit flies were exposed to imidacloprid […]

(Beyond Pesticides, August 26, 2020) Neonicotinoid insecticides damage the health of shrimp and oysters, according to two (1, 2) new studies published by Australian researchers. Although this class of chemicals is best known for its hazardous impacts on pollinator populations, it is becoming increasingly clear that the entire food chain is at risk from continued neonicotinoid use. This study builds on an already established body of literature showing these systemic chemicals poison waterways. Researchers began by collecting samples of shrimp and oysters from growers along the coast, and acclimating the species to laboratory conditions. Both collections were separated into different test groups. Oysters where exposed in their tanks to various concentrations of the neonicotinoid imidacloprid. Shrimp were exposed to imidacloprid through two methods: in their feed, and in their tanks. Each separate test group was further separated into high and low exposures. A control group that did not receive any pesticide exposure was also established in each experiment. For the oyster populations, scientists found a range of negative effects. Imidacloprid inhibits the proper functioning of the enzyme acetylcholinesterase, a well-known impact of many pesticides that results in damage to the nervous system. Detoxification mechanisms are activated, and changes are observed […]

(Beyond Pesticides, August 6, 2020) New research finds that a decline in wild pollinator abundance, notably wild bees, limits crop yields in the U.S., according to the study, “Crop Production in the USA Is Frequently Limited by A Lack of Pollinators.” The study results, published in the journal Proceedings of the Royal Society B, find the annual, national average value of wild bee pollination for the most economically important and pollinator-dependent crops is approximately $1.5 billion, with the total value of all U.S. pollinator-dependent crops equaling $50 billion annually. The United Nations states that 75% of the 115 top global food crops depend on insect pollination, with one third of all U.S. crops dependent on pollinators, according to the U.S. Department of Agriculture (USDA). However, research finds that many insect populations are declining by half with a third threatened by extinction, including managed and wild pollinators, mainly due to habitat fragmentation, climate change, and extensive pesticide use. With the global reliance on pollinator-dependent crops increasing over the past decades, a lack of pollinators threatens food security and stability. The researchers in the study note, “Our findings show that pollinator declines could translate directly into decreased yields or production for most of the crops studied, […]

(Beyond Pesticides, July 28, 2020) With honey bees around the world under threat from toxic pesticide use, researchers are investigating a new way to track environmental contaminants in bee hives. This new product, APIStrip (Adsorb Pesticide In-hive Strip), can be placed into bee hives and act as a passive sampler for pesticide pollution. Honey bees are sentinel species for environmental pollutants, and this new technology could provide a helpful way not only for beekeepers to pinpoint problems with their colonies, but also track ambient levels of pesticide pollution in a community. According to a study published by an international team of researchers, APIStrip has the potential to detect 442 pesticides as well as their primary break down products at levels lover than parts per billion. The strip, comprised of polymer, is what scientists describe as “a bee-proof, in-hive passive sampler.” Current methods of sampling honey bee hives for contaminants is time-consuming, requiring removal of bees, pollen, honey or beeswax, and can result in significant hive disturbance. This new method was piloted by citizen-science beekeepers, and according to researchers proved to be a simple and effective tool that any interested citizen-scientist could employ. Passive sampling of environmental contaminants by citizen scientists […]

(Beyond Pesticides, July 16, 2020) Long-term exposure to sublethal (low-level) concentrations of the neonicotinoid in soil negatively affects the health and behavioral development of black garden ants (Lasius niger) colonies, according to a study published in Communications Biology by scientists at the University of Bern, Switzerland. Ants are one of the most biologically significant insects in the soil ecosystem, acting as ecosystem engineers. Their burrowing behavior aerates the soil, allowing oxygen and water to penetrate down to plant roots. Additionally, ants increase soil nutrient levels by importing and accumulating organic material like food and feces, thus enhancing nutrient cycling. Like many other insects, ants are unfortunate victims of the global insect apocalypse or population decline, and much research attributes the recent decline to several, including pesticide exposure. Broad-spectrum pesticides, like neonicotinoids, indiscriminately kill pests and nontarget organisms alike, as their ubiquitous use contaminates soils, even in untreated areas. This study highlights the necessity of rethinking chemical pest management, developing sustainable agricultural practices that reduce the use of agrochemicals, like pesticides, to prevent permanent environmental ecosystem damage. Researchers in the study note, “To prevent irreparable damages to functioning ecosystems, [we] suggest to either fully incorporate long-term effects in risk assessment schemes, or to make a shift […]

(Beyond Pesticides, June 23, 2020) Next-generation systemic insecticides, billed by the agrichemical industry as “safer for bees” than neonicotinoids, have been found to stress and kill honey bees. As reported, a study by researchers at Oregon State University in the journal PLOS One, sulfoxaflor and flupyradifurone (in the products Transform and Sivanto, respectively) were found to increase apoptosis (cell death) and increase oxidative stress in exposed honey bees. The study indicates that, “With the recent Environmental Protection Agency (EPA) approval for use of both flupyradifurone and sulfoxaflor, and with the growing concern regarding pollinator health, it is important to better understand any potential negative impacts (especially sub-lethal) of these pesticides on bees.” However, this statement begs the question ‘why these two new bee-toxic pesticide were approved by EPA in the first place.’ This process is familiar and frustrating to those who continue to fight against the decline of pollinators: the chemical industry introduces and EPA approves new toxic pesticides marketed as “safer” to the specific problem caused by its older products, only to find out through independent and academic research that the problem is not solved in the least. Researchers conducted two exposure assessments: one six-hour long study, and another […]

(Beyond Pesticides, June 22, 2020) In the wake of the national groundswell for equity and justice in the face of rampant inequality and police brutality against people of color, we acknowledge, during Pollinator Week, holistic actions are needed to solve systemic societal problems that cause racial disparities. Those fighting for environmental justice understand that the harms inflicted by toxic chemical production and use cause disproportionate adverse effects on people of color—from fenceline communities near chemical production plants, to the hazardous and inhumane working conditions in agricultural fields, to the elevated risk factors for black and brown people from toxic pesticide exposure patterns.  Pollinator Week reminds us that we must nurture the ecosystem, which we depend on for life, with a fierce commitment to its inhabitants and a focus on those at highest risk. Therefore, this week is a time to renew our commitment to environmental justice and seek the adoption of policies and practices in our communities, and across the nation and the world, that recognize the urgency to address the disproportionate harm inflicted by toxic pesticide use.  TAKE ACTION! Here are three things you can do today. Protect Low-Income and People of Color Communities—As The Black Institute in New […]

(Beyond Pesticides, June 12, 2020) New research finds that western monarch milkweed habitat contains a “ubiquity of pesticides” that are likely contributing to the decline of the iconic species. The research, published in Frontiers in Ecology and Evolution, provides a grim snapshot of a world awash in pesticides, and raises new questions about the U.S. regulatory process that continues to allow these toxic chemicals on to the market without adequate review and oversight. “We expected to find some pesticides in these plants, but we were rather surprised by the depth and extent of the contamination,” said Matt Forister, PhD, a butterfly expert, biology professor at the University of Nevada, Reno and co-author of the paper in a press release. “From roadsides, from yards, from wildlife refuges, even from plants bought at stores—doesn’t matter from where—it’s all loaded with chemicals. We have previously suggested that pesticides are involved in the decline of low elevation butterflies in California, but the ubiquity and diversity of pesticides we found in these milkweeds was a surprise,” Dr. Forister said. The researchers collected over 200 milkweed samples from nearly 20 different sites across the Central Valley of California, as well as from retailers that sell milkweed […]

(Beyond Pesticides, June 9, 2020) EPA has received applications from the states of Maryland, Pennsylvania, and Virginia for the “emergency” use of the bee-toxic neonicotinoid insecticide dinotefuran to control brown marmorated stinkbugs in pome and stone fruits. These three states (and others) have received emergency exemptions for this use for the nine previous years and it must not be allowed for a tenth year. Rather than skirt the regulatory process of review, this use pattern must be subject to EPA registration review in combination with all other neonicotinoid uses. Sign the Petition to EPA and Send a Letter to Your Congressional Representative and Senators: EPA Must Deny Routine “Emergency” Exemptions As a neocotinoid insecticide, dinotefuran presents an alarming hazard to bees and other pollinators. Like other neonicotinoids, it is systemic and can indiscriminately poison any insects feeding on nectar, pollen, or exudates. It is also highly toxic to aquatic invertebrates and soil organisms, as well as being highly persistent. In addition to the serious ecological impacts, dinotefuran is toxic to the immune system. This is, of course, an effect that should avoided during the coronavirus pandemic—when the immune system is under attack. Section 18 of the federal pesticide law (FIFRA—Federal Insecticide, Fungicide, […]