(Beyond Pesticides, March 14, 2019) A study, supported by the USDA’s National Institute of Food and Agriculture, finds that state pesticide preemption laws “compromise public health and economic well-being” by preventing localities from enacting pesticide use restrictions on private property that are more restrictive than their state’s regulations. In the words of the authors, “By eliminating the ability of local governments to enact ordinances to safeguard inhabitants from health risks posed by pesticides, state preemption laws denigrate public health protections.” The study, Anti-community state pesticide preemption laws prevent local governments from protecting people from harm, published in the International Journal of Agricultural Sustainability, reviews scientific and historical evidence of the failure of state and federal pesticide laws to protect localities from pesticide poisoning, and highlights the inability of localities to compensate for that failure under present laws. Communities seeking to protect their residents would typically issue community-wide restrictions to ensure protection of shared community resources, including air, land, and waterways, from pesticide drift, runoff, and other nontarget effects —as is the case with other community decisions on recycling, smoking, and zoning. The study’s authors document how industry influence led to the adoption of state laws that undermine the ability of localities […]

(Beyond Pesticides, March 1, 2019) The costs of pesticide use extend far beyond the invoices farmers pay for purchase of the chemicals to use on their crops. The real costs related to pesticide use and exposure include those of health care, lost productivity and income, and environmental damage (loss of environmental services and biodiversity; compromised air, water, and soil quality). There has been relatively little research focused on those real and extensive costs; this Daily News Blog turns its attention to several that have made the attempt. January 2019 saw the publication of a new book, Sicker Fatter Poorer: The Urgent Threat of Hormone-Disrupting Chemicals to Our Health and Future … and What We Can Do About It, by Leonardo Trasande, MD, MPP, which examines how some chemicals — including organophosphate and organochlorine pesticides — disrupt human endocrine (hormonal) function, and damage health, sometimes irreparably. The book further investigates the economic costs of associated diseases and other health problems to the U.S. economy — on the order of 2.3% of GDP (gross domestic product), or $340 billion, annually. As Dr. Trasande notes, “The reality is that policy predicts exposure, exposure predicts disease and disease ultimately costs our economy.” Dr. Trasande is […]

(Beyond Pesticides, February 15, 2019) A study, published in January 2019 in the journal Environmental Health, demonstrates that consumption of organic foods reduces significantly the levels of synthetic pesticide residues in the bodies of U.S. children and adults. Pesticide residues are found four times as frequently in conventionally grown food as in organically produced foodstuffs. Although the number of subjects in this study was relatively small, the results point to the importance of organics, and add to the evidence that organic food production and consumption are key to protecting human health. Study subjects comprised members of racially diverse families — from Oakland, Minneapolis, Baltimore, and Atlanta — who did not typically consume an organic diet. Study participants, ages 4 to 52, ate their typical diet of conventionally grown foods for five days; for the following six days, they switched to a certified organic diet (provided by researchers) for consumption at home, work, school, or daycare, including all foods and beverages other than water. Urine samples were gathered prior to the “organic” days, and first thing on the morning after those six days. Fourteen different pesticides and metabolites were present in all participants’ urine in the “pre-organic” analysis; following the organic diet […]

(Beyond Pesticides, December 18, 2018) The ingredients not listed on a pesticide product are not fully reviewed for their adverse effects may be the most toxic chemicals in the formulation. Recent research, Toxicity of formulants and heavy metals in glyphosate-based herbicides and other pesticides (Toxicology Reports 5, 2018), by Defarge, de Vendômois, and Séralini demonstrates the need to disclose and test all ingredients in pesticide products, as well as the full formulation that includes “inert” or nondisclosed ingredients. While glyphosate/Roundup is obviously not allowed to be used in organic production, this research reaffirms the need to evaluate full formulations of substances allowed for use in organic. The research on glyphosate tested the toxicity of the herbicide glyphosate, “inerts” in glyphosate-based herbicides (GBH), and the pesticide formulations–looking at toxicity to target organisms, toxicity to human cells, and endocrine-disrupting activity. In addition to the GBH products, the researchers studied a number of other pesticides. Tell NOP and USDA that “inerts” used in organic production must receive full review by the NOSB. “Inert” ingredients are allowed in pesticides used in organic production as well as those used in chemical-intensive production. The National Organic Program (NOP) allows “inerts,” permitted in conventional production and formerly listed […]

(Beyond Pesticides, December 6, 2018) A recent analysis of annual drinking water quality reports has revealed that many community drinking water systems in the Midwest have seasonal exceedances of the allowable limit for the herbicide atrazine. Atrazine, linked to endocrine disruption, neuropathy, and cancer, is the second most widely used pesticide in corn growing areas, with over 73 million pounds applied to agricultural fields each year.  A 2009 study by Paul Winchester, MD, professor of clinical pediatrics at Indiana University School of Medicine and a neonatologist at St. Francis Hospital in Indianapolis, linked birth defects to time of conception, with the greatest impact on children conceived when concentrations of atrazine and other pesticides are highest in the local drinking water. (See Reproductive Effects Peak with Pesticide Exposure.) During peak use, atrazine levels in drinking water have been recorded at three to seven times above the legal limit. In addition to the well documented impact on the environment, recent  studies have linked prolonged pesticide exposure to not only shortened gestation and preterm birth for women, but also neurodevelopment delays in children. Ultimately, these unreported seasonal peaks may result in persistent adverse health impacts in impacted communities. The Safe Drinking Water Act (SDWA), enacted in 1974, […]

(Beyond Pesticides, November 26, 2018) Organic consumers expect that the organic products they buy are grown without toxic chemical inputs. However, oil and gas wastewater (including fracking wastewater) is currently used to irrigate crops. Among the chemicals known to be present in oil and gas wastewater are heavy metals and other chemicals with carcinogenic, reproductive, developmental, endocrine-disrupting, and other toxic effects. When the Organic Foods Production Act (OFPA) was passed, and regulations adopted, there was no agricultural use of oil and gas wastewater, so the regulations did not address these hazards.  Tell USDA to Outlaw Fracking Wastewater in Organic Production!  The Cornucopia Institute has filed a petition for rulemaking, asking that oil and gas wastewater be ruled a prohibited substance in organic production. This issue should be put on the work agenda of the National Organic Standards Board (NOSB), which advises the Secretary about issues concerning NOP. The petition from the Cornucopia Institute contains information that will serve as support for the work agenda item. Over the past several years, the NOSB has received many comments requesting them to address this issue Among the comments have been suggestions for guidance to farmers faced with contamination from oil and gas activities. The […]

(Beyond Pesticides, November 2, 2018) A group of leading toxics experts, who published a paper in the journal PLOS Medicine on their research on organophosphate exposure during pregnancy and impacts on child development, are calling for a ban on organophosphate pesticides. The study evaluates current science on the risks of this class of compounds, produced by Corteva Agriscience (formerly Dow AgroSciences); its conclusions warn of the multitude of dangers of organophosphates for children, and makes recommendations for addressing these risks. The experts conclude that: (1) widespread use of organophosphate (OP) pesticides to control insects has resulted in ubiquitous human exposures; (2) acute exposures to OPs is responsible for poisonings and deaths, particularly in developing countries; and (3) evidence demonstrates that prenatal exposures, even at low levels, put children at risk for cognitive and behavioral deficits, and for neurodevelopmental disorders. Among the authors’ recommendations are these: Governments and subsidiary agencies, including the Environmental Protection Agency (EPA), should phase out chlorpyrifos and other organophosphate pesticides; ban non-agricultural uses of OP pesticides (including in household products); monitor watersheds and drinking water sources of human exposure; promote the use of integrated pest management (IPM) through incentives and training; and establish pesticide use and illness reporting […]

(Beyond Pesticides, July 27, 2018) The American Academy of Pediatrics (AAP) has issued new guidelines for measures to lower children’s exposures to chemicals in food and food packaging that are tied to health problems such as obesity, metabolic changes, decreased birth weight, and endocrine disrupting effects, including reduced fertility. Exposures to these chemicals–added to food during processing or in food packaging–are disproportionately high among minority and low-income populations, according to the report, especially given inadequate federal regulation and oversight. The guidelines, issued in both a statement and technical report by the AAP entitled, Food Additives and Child Health, came after the group decided to review and highlight emerging child health concerns related to “the use of colorings, flavorings, and chemicals deliberately added to food during processing (direct food additives) as well as substances in food contact materials.” Food additives, in particular, have been documented to be linked to endocrine disruption and other adverse health effects. According to AAP, “regulation and oversight of many food additives is inadequate because of several key problems in the Federal Food, Drug, and Cosmetic Act. Current requirements for a “generally recognized as safe” (GRAS) designation are insufficient to ensure the safety of food additives and do not […]

(Beyond Pesticides, May 22, 2018)  A staggering 209 million pounds of pesticides were used in California in 2016, according to the latest data released by the Department of Pesticide Regulation (DPR). This figure refers only to applied “active” pesticide ingredients and not “inerts,” which often account for 80 to 99 percent of pesticide products and can be equally hazardous to human health and the environment. Even though pesticide use in the state has dropped by 1.4 percent from the previous year, pesticide use in 2016 was still the third highest in recorded history, since the inception of DPR’s comprehensive data collection program in 1990. In fact, the total pesticide use was only six million pounds shy of the highest amount ever recorded – 215 million pounds in 1998. The land area treated with carcinogens is as large as the size of New Jersey and Connecticut combined. Nearly 102 million cumulative acres of land were treated with pesticides in the state, ranging in toxicity from low to high risk. Each time an acre is pesticide-treated in a given year, DPR adds the acre to its cumulative list, even if the treatment is repeated on the same land. The 2016 figure represents an […]

(Beyond Pesticides, December 13, 2017) A recent study finds that environmental exposures contribute to increasing disease burden and corresponding health costs that may exceed 10% of global gross domestic product (GDP). Neurological impairments particularly add significant costs to both individuals and societies. This European study combined cost calculations for exposures to environmental chemicals, including pesticides, air pollution, and endocrine disrupting substances, and suggests that a shift in priority setting for environmental policy is needed. The study’s authors, from Harvard University, the University of Southern Denmark, and the EHESP School of Public Health in France, say that calculations currently used as international references are “serious underestimations” of the economic costs associated with preventable environmental risk factors. Published in Environmental Health, the study, Calculation of the disease burden associated with environmental chemical exposures: application of toxicological information in health economic estimation, combined and extended cost calculations for exposures to environmental chemicals, including neurotoxicants, pesticides, air pollution, and endocrine disrupting chemicals, where sufficient data were available to determine dose-dependent adverse effects. The study utilized risk valuations to assess the environmental burden of disease, and used country-specific monetary values of metrics for length and quality of life (Disability-Adjusted Life year or DALY – a […]

(Beyond Pesticides, October 31, 2017) Scientists warn that inadequate federal testing, disproportionate industry influence, and subverted regulatory oversight threaten decades of progress on protecting people from hormone disrupting chemicals. This from a new paper with findings that regulators face a critical need to fully understand and address the hazards from these dangerous substances. Hormone disrupting chemicals, also known as endocrine disruptors, are substances that have been shown to interfere with the hormone system, leading to long-term health impacts ranging from cancer to neurological developmental impairments. Even small alterations in hormone concentrations, particularly during “critical windows” of embryonic development and developmental phases of life, can have lasting and significant effects. Mounting science is showing that disruptions to the hormone system can occur at very low doses that are lower than those used in traditional toxicity testing. Now, commentary from scientists at Rutgers University and North Carolina State University, “Endocrine disrupting chemicals and behavior: Re-evaluating the science at a critical turning point,” states that inefficient federal testing and outsized industry influence in Washington threaten decades of progress. “The significant progress made over the past couple of decades to understand endocrine disrupting chemical-related effects and mitigate exposures is now at serious risk,” write the authors […]

(Beyond Pesticides, October 19, 2017) Exposure to the second most commonly used herbicide in the U.S., atrazine, results in a lower proportion of male frogs in populations of Blanchard’s cricket frogs, according to researchers from Ohio’s Miami University. While it may be ostensibly easy to dismiss the results of this study as limited to a single frog species, the Blanchard cricket frog, with its populations concentrated in heavily farmed Midwestern states, is likely an important indicator of broader ecological impacts. Ultimately, only a transition away from toxic herbicides and towards integrated organic systems will successfully address the ongoing effects of industrial agrichemicals on amphibians. Miami researchers exposed frogs to varying concentrations of atrazine, 0.1, 1, and 10 μg/L, in the laboratory, in order to investigate sex ratios and potential effects on survival of the population. Although no significant effects were seen on survival rate during the course of the study, sex ratios were significantly altered at the 0.1 and 10 μg/L exposure concentrations. At these levels, populations developed 51 and 55% fewer males respectively than control frogs. Researchers point out that such significant results seen at such low concentrations likely indicates that sex ratios are also skewed in the wild. […]

(Beyond Pesticides, September 1, 2017) Tell your Governor to stop Monsanto from making false and deceptive claims about glyphosate (Roundup) –a pesticide that hurts workers. Because of its wide use by workers in parks, along utility and railroad rights-of-way, and on farms, use of Monsanto’s glyphosate results in more exposure than any other pesticide. Monsanto has developed and continues to grow its market for this product with false claims of the safety of the toxic chemical. Glyphosate is listed as a probable carcinogen by the International Agency for Research on Cancer (World Health Organization) and disrupts a pathway in humans necessary for healthy functioning of the gut microbiome. Meanwhile, Monsanto actively advertises and promotes its Roundup products as targeting an enzyme “found in plants but not in people or pets.” Act now to urge your Governor to act on false claims by Monsanto. Although EPA considers glyphosate to be “of relatively low oral and dermal acute toxicity,” symptoms workers could experience following exposure to glyphosate formulations include: swollen eyes, face, and joints; facial numbness; burning and/or itching skin; blisters; rapid heart rate; elevated blood pressure; chest pains, congestion; coughing; headache; and nausea. The additional ingredients in Roundup can be more toxic […]

(Beyond Pesticides, July 28, 2017) According to a report released earlier this month by the Coalition for Safer Food Processing and Packaging, a national alliance of leading public health and food safety groups, toxic, hormone disrupting, industrial chemicals have been found in 10 varieties of macaroni and cheese products. The coalition is calling on food companies, especially the Kraft Heinz Company, maker of the iconic boxed mac and cheese, to eliminate sources of these chemicals from their cheese products. The tested mac and cheese products contained elevated levels of phthalates, chemicals used in industrial processing of plastics, adhesives and rubber, among other things, as well as “inert” ingredients in pesticide products. The study tested 30 items of individual cheese products from various manufacturers that were purchased at retail grocery stores in the U.S and shipped to the lab, unopened, in their original packaging. The cheese product items tested include nine of Kraft’s many cheese products. Results found that nearly every cheese product tested contained 10 different phthalates, with six found in a single product. Eight of the nine Kraft mac and cheese products tested contained phthalates. DEHP, a phthalate currently banned in several countries, was found in 10 of the mac […]

(Beyond Pesticides, July 27, 2017) Earlier this week U.S. Senators Tom Udall (D-NM) and Richard Blumenthal (D-CT) introduced a bill that would ban use of the insecticide chlorpyrifos. The Protect Children, Farmers and Farmworkers from Nerve Agent Pesticides Act, S. 1624, comes one week after an appeals court refused to require the U.S. Environmental Protection Agency (EPA) to make a decision over whether to ban the chemical. Removing this neurotoxic insecticide from the environment would significantly reduce health risks for children and farmworkers in underserved rural communities, build pressure to address all toxic organophosphates, and help push U.S. agriculture in a more sustainable direction. As with other organophosphate class chemicals, chlorpyrifos, first registered in 1965 by Dow Chemical, is derived from nerve agents used during World War 2. The chemical is linked to a range of negative health and environmental outcomes that warrant its prohibition. Children are at particular risk from the chemical due to their developing immune, organ, and nervous systems.  As with other organophosphate nerve agents, the chemical acts on the body’s nervous system, inhibiting the movement of neurotransmitters called cholinesterase. Chlorpyrifos chemically binds to the site where cholinesterase would in the body, preventing normal nerve impulse transmission. […]

(Beyond Pesticides, July 24, 2017) A new report by the National Academies of Sciences, Engineering, and Medicine (NAS) is recommending to the U.S. Environmental Protection Agency (EPA) a strategy to evaluate the evidence of adverse human health effects from low doses of exposure to chemicals that can disrupt the endocrine system. NAS believes that EPA’s current process, which utilizes traditional toxicity testing, would miss some effects that occur at doses lower then what EPA evaluates. EPA’s Endocrine Disruption Screening Program (EDSP) is currently screening chemicals for their potential to interact with the endocrine system, but the program is years behind schedule and has been criticized for using outdated methods. Endocrine disruptors are substances that can cause a variation in normal hormone function. Even small alterations in hormone concentrations, particularly during embryonic development and developmental phases of life, can have lasting and significant effects. Mounting science is showing that disruptions to the hormone system can occur at very low doses that according to NAS, are lower than those used in traditional toxicity testing by EPA. This means that some effects may be missed. EPA’s methodologies have been criticized over the years for failing to adequately capture impacts at low doses. EPA requested NAS […]

(Beyond Pesticides, July 21, 2017) A March 2017 review of studies on the agricultural use of glyphosate (the active ingredient in “Roundup” and other formulated herbicides) points to widespread persistence in soils subject to long-term, intensive glyphosate use, and myriad resulting concerns about impacts on soil and environmental health. The review, by Robert J. Kremer, PhD, of the University of Missouri School of Natural Resources, cites concerns that include: reduction of nutrient availability for plants and organisms; disruption to organism diversity, especially in the areas around plant roots; reductions of beneficial soil bacteria; increases in plant root pathogens; disturbed earthworm activity; reduced nitrogen fixing at plant roots; and compromised growth and reproduction in some soil and aquatic organisms. Globally, glyphosate is the most widely used herbicide compound: in 2017, worldwide use is estimated to be approximately 1.35 million metric tons. Use in the U.S. has risen dramatically — from 2.72–3.62 million kg in 1987 to approximately 108 million kg in 2014, and 15-fold since 1996, when genetically engineered (GE) glyphosate-tolerant crops were introduced. Use has grown for a number of reasons, including more-intensive use as resistance to the herbicide grows. Researchers have found that, after years of consistent application to […]

(Beyond Pesticides, June 29, 2017) On June 16, the European Chemicals Agency (ECHA) decided to classify bisphenol A (BPA) as an endocrine disruptor, and as a substance of “very high concern” due to “probable serious effects to human health.” The classification follows a proposal by the French food security agency (ANSES), which was made earlier this year. The committee, comprised of representatives from all 28 European Union EU countries, agreed to the classification unanimously. With pressure from environmental groups and others, the European Commission (EC) is working to define scientific criteria that will be used to identify endocrine disrupting chemicals (EDCs), and lead to more effective regulation in EU countries. In June 2016, the EC issued weak regulations on endocrine disruptors in pesticide products, undermining the precautionary legal standard that governs pesticide usage in Europe. Many scientists and advocacy organizations criticized the proposed regulations for creating an impossibly high burden of proof for defining harm from endocrine disrupting pesticides and other products. EDCs contained in common household products such as detergents, disinfectants, furniture, plastics, and pesticides, interfere with the body’s hormone system either by mimicking naturally produced hormones, blocking hormone receptors in cells, or effecting the transport, synthesis, metabolism or excretion […]

(Beyond Pesticides, June 21, 2017) More than 200 international scientists and medical professionals have signed the Florence Statement on Triclosan and Triclocarban, which states that triclosan and its chemical cousin triclocarban pose a risk to human health, and urges the international community to limit use of these antimicrobials, which are associated with bacterial resistance and no more effective than soap and water. In 2016 after manufacturers failed to prove efficacy, the U.S. Food and Drug Administration (FDA), which regulates cosmetic triclosan products, announced that manufacturers must, by September 2017, remove triclosan from over the counter hand soaps. The agency still allows the chemical in toothpastes and other products, such as hand wipes. The Environmental Protection Agency (EPA), which regulates triclosan in household items, textiles and plastics, still permits wide use of the chemical in a range of products. The Florence Statement on Triclosan and Triclocarban is “based on extensive peer-reviewed research,” and “concludes that triclosan and triclocarban are environmentally persistent endocrine disruptors that bioaccumulate in and are toxic to aquatic and other organisms.” The statement includes evidence of human health threats, and provides recommendations intended to mitigate harm from triclosan, triclocarban, and other similar antimicrobials. The recommendations are listed below: “Avoid […]

(Beyond Pesticides, June 2, 2017) According to a new study, levels of triclosan spike in the bodies of children after they brush their teeth or wash their hands. Triclosan, a controversial antimicrobial, is frequently added to consumer care products. Last year, the Food and Drug Administration (FDA) banned the use of triclosan in hand soaps, but it is still allowed in toothpaste and numerous plastic and textile products regulated by the U.S. Environmental Protection Agency (EPA). Many companies had previously decided, due to consumer pressure, to remove triclosan from hand soaps years ahead of the FDA decision. Researchers collected and tested the urine of 389 mothers and their children –three times during pregnancy, and then took between 1-6 samples from children between the ages of 1 and 8 years old. The researchers found triclosan in over 70% of samples taken. In the group of 8 year olds, they report that levels were 66% higher in the children that used hand soap. For those that wash their hands over five times a day, the levels increase more than four times in comparison to children who wash their hands once or less per day. For toothpaste, researchers find that children who had […]

(Beyond Pesticides, April 4, 2017) Exposure to commonly used pyrethroid insecticides results in the early onset of puberty in boys, according to a study presented at the 99th meeting of the Endocrine Society in Orlando, Florida this week. Pyrethroids, which exhibit endocrine disrupting properties, have the ability to interfere with the proper regulation of the human body’s hormonal system. This research is the first to investigate not only the association between pyrethroids and accelerated puberty, but also the causal mechanisms involved in the physiological changes taking place within the human body. For the study, Jing Liu, PhD, and colleagues from Zhejuang University in China, analyzed the urine in 463 Chinese boys aged 9 to 16 for the presence of metabolites from the pyrethroid insecticide cypermethrin. Results show that a 10% increase in the metabolite 3-PBA is associated with a roughly 4% increase in luteinizing and follicle-stimulating hormones, which facilitate puberty and sperm production. The author’s note that, “Boys with increased urinary levels of 3-PBA have a significantly increased risk of earlier pubertal onset, in which the odds of being in an advanced pubertal stage are increase by 73% to 110%.” The study, acknowledging the limitation in determining causality, further investigates the […]

(Beyond Pesticides, March 2, 2017) On Tuesday, the European Commission (EC) refrained from voting on proposed scientific criteria that would have identified endocrine disrupting chemicals (EDC) and led to regulation on their use in EU countries. This sends the Commission back to the drawing board on the proposal, on which they hope to eventually take a formal vote. The failure to move forward with defined criteria on these hazardous chemicals, which are present in pesticides, biocides, and self-care products, is still largely due to the disagreements of voting member states over the rules reflecting hazard or risk-based criteria. There have been several other meetings of the member states on this proposal, including a meeting in December which highlighted the inadequacies of the criteria. After this meeting, according to Bas Eickhout, of the Greens-European Free Alliance, “Under the Commission’s criteria, it is likely that not a single substance would be identified as an endocrine disrupter, and they would effectively escape specific regulation.” This all follows on the weak regulations issued by the EC in June 2016 to regulate endocrine disruptors in pesticide products, which ultimately undermine the precautionary legal standard that governs pesticide usage in Europe. Many scientists and advocacy organizations criticized […]

(Beyond Pesticides, January 11, 2017) Ultra-low doses of glyphosate formulations fed to rats is linked to an increased likelihood of developing non-alcoholic fatty liver disease (NAFLD), according to a recently published study in the journal Nature. A lead author of the study, Michael Antoniou, PhD, stated that the findings are “very worrying as they demonstrate for the first time a causative link between an environmentally relevant level of Roundup consumption over the long-term and a serious disease.” The findings point to the growing need to eliminate the widespread use of this herbicide, as it has already been implicated in endocrine disruption, reproductive effects, and kidney and liver damage. The researchers analyzed female rat livers obtained from a previous 2-year study on Roundup toxicity using molecular profiling techniques. These rats were administered Roundup via drinking water at a concentration of 0.1 ppb, which is an allowable level within both the U.S. and the European Union. The molecular analyses conducted by researchers on the internal organs of the rats fed Roundup included testing of liver cell disturbances. Overall, ultra-low dose glyphosate-formulation exposure led to observations of biomarkers also seen in fatty liver disease. These findings have human health implications “since NAFLD is predicted to be the […]