(Beyond Pesticides, January 22, 2021) After the past four devastating years, hopes and expectations of the Biden/Harris administration abound among the environmental and public health communities. The ears and eyes of many advocates, as well as those in the agricultural community, are attuned (among myriad candidates) to the fate of the pesticide aldicarb. Although Environmental Protection Agency (EPA) registration of this terribly toxic insecticide was cancelled in 2010, various limited-use reapprovals since then have meant that the compound has found its way to increasing levels of use. On January 12, as another parting shot of midnight rulemaking, Trump’s EPA approved expanded uses (see below). The $64,000 question is whether the new administration will use its authority under the Congressional Review Act — which enables Congress to pass a joint resolution (then signed by the President) to overturn a new federal agency rule and prevent its reissuance in the future — to get this pesticide retired for good. Beyond Pesticides urges President Biden’s EPA to do so. Notably, the Trump administration used the Congressional Review Act to destroy myriad environmental rules when it came into power. This permitting of expanded aldicarb uses fits the pattern. Environmental Health News notes that, as of early […]

(Beyond Pesticides, December 23, 2020) The litany of parting shots by the waning Trump administration got longer on December 4, when the Environmental Protection Agency (EPA) announced a proposed interim decision on the very toxic pesticide chlorpyrifos, functionally continuing its registration for many agricultural uses. The interim decision purports to put in place new limitations on use of this pesticide, but they are wholly inadequate to the threat this compound represents — to young children, most concerningly, as well as to farmworkers, critical species and ecosystems, and the public. Chlorpyrifos should not be re-registered for use — i.e., its sale and use should be banned altogether, as Beyond Pesticides has asserted for years. Chlorpyrifos is an organophosphate pesticide used on scores of food crops, for mosquito (and other pest) control, and for some turf management (golf courses, especially). It has been demonstrated to be highly neurotoxic, especially to young children, leading to impaired cognitive function, developmental delays, lower IQs, attention deficit disorder, and a variety of other pervasive developmental and learning disorders. The essence of the compound’s toxicity to developing brains lies in its function as a cholinesterase inhibitor; chlorpyrifos binds to the receptor sites for acetylcholinesterase (AChE), an enzyme […]

(Beyond Pesticides, December 7, 2020) The Trump Environmental Protection Agency (EPA) reversed in four years much of the progress made by EPA in decades, and that push continues. The Biden EPA needs to advance a new vision. Tell President-elect Biden to adopt a new direction for pesticide regulation. Challenge so-called “benefits” of pesticides. The Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) requires EPA to weigh risks against benefits when registering pesticides. Claimed “benefits” for toxic pesticides need to be judged in comparison to organic production, which is able to produce all types of food and feed. The Organic Trade Association reports that organic sales now exceed $55 billion per year, and the U.S. Department of Agriculture (USDA) finds that organic producers in the U.S. produced $9.9 billion worth of organic food on 5.5 million acres in 2019. EPA assumes benefits of pesticides, rather than measuring them, and does not take into account the development of resistance. The cost-competitive success of organic food production and nonagricultural land management practices make the case that toxic pesticides lack benefits. Protect pollinators. Agriculture relies on insect pollinators to facilitate fertilization and maintain annual crop yield. Globally, the production of crops dependent on pollinators is worth […]

(Beyond Pesticides, December 4, 2020) Amid the maelstrom of national political news related to the recent election, and the Trump administration’s upcoming exit, comes a release of the Environmental Protection Agency’s (EPA’s) draft biological evaluation (BE) of glyphosate. The assessment indicates that use of this ubiquitous herbicide likely threatens nearly every animal and plant species on the U.S. list of threatened and endangered species — 93% of them, in fact. Chemical and Engineering News reports that the EPA announcement was made public only a few days after the agency also reported that atrazine (another commonly used and toxic herbicide) probably harms more than half of those species. Given the Trump EPA’s eagerness, during the past four years, to serve industry interests rather than protect human health, biodiversity, and functional ecosystems, the timing of this released evaluation during the so-called “lame duck” period is puzzling. Glyphosate is the active ingredient in many herbicides, including RoundupTM, Monsanto’s (now Bayer’s) ubiquitous and widely used weed killer; it is very commonly used with genetically modified companion seeds for a variety of staple crops, as well as for weed control on managed landscapes. These seeds are genetically engineered to be glyphosate tolerant. Glyphosate-based herbicides are the most […]

(Beyond Pesticides, November 18, 2020) The herbicide atrazine is likely to adversely affect over half of endangered species listed in the United States, according to a report released by the U.S. Environmental Protection Agency (EPA) as part of a legal agreement with the Center for Biological Diversity (CBD). Based on both adverse human health and environmental threats, Beyond Pesticides joined with Center for Food Safety, CBD, and other public-interest groups in October to sue EPA over its decision to reapprove atrazine, an endocrine-disrupting herbicide banned across much of the world. These actions follow the agency’s recent reapproval of atrazine, which reduced a number of safeguards for public health and the environment, and it’s enactment of rules that limit endangered species reviews.  See (Lawsuit Challenges EPA Reapproval of Endocrine-Disrupting Pesticide Atrazine: Agency Slashes Protections for Children, Waterways.) Although advocates are hopeful that the next administration will shift toward an EPA that lives up to its namesake, there is considerable ground to make up. Atrazine is an herbicide that disrupts the endocrine system by mimicking the body’s natural hormones, binding to hormone receptors in the body. In humans, the effect can result in birth defects, damage to the reproductive system, and chronic […]

(Beyond Pesticides, November 6, 2020) Beyond Pesticides joined health and environmental groups suing the U.S. Environmental Protection Agency (EPA) late last month over its decision to reapprove the endocrine disrupting herbicide atrazine with fewer protections for children’s health. Despite the chemical being banned across much of the world, EPA continues to make decisions that benefit chemical industry executives. “EPA’s failure to remove atrazine represents a dramatic failure of a federal agency charged with safeguarding the health of people, wildlife, and the environment,” said Jay Feldman, executive director of Beyond Pesticides. “We seek to uphold the agency’s duty to act on the science, in the face of viable alternatives to this highly toxic weedkiller.” It is not hyperbole, but in fact scientifically documented, that atrazine exposure “chemically castrates” frogs, impairs fish reproduction, and can result in birth defects and cancer in humans. EPA decision comes on the heels of a rash of industry-friendly decisions. Within the last month, the agency has finalized rules weakening farmworker buffer zone protections, reapproving dicamba use on genetically engineered crops, and reregistering some of the most toxic pesticides on the market. The lawsuit, filed in the Ninth Circuit Court of Appeals, contends that before reapproving atrazine, […]

(Beyond Pesticides, October 19, 2020) The COVID-19 epidemic has made clear to the general public what we at Beyond Pesticides have been stressing since our inception—some populations have disproportionate risk of severe outcomes, exposures to toxic chemicals can affect susceptibility to disease, comorbidity increases risk, and bad government can kill you. As Trump declares that “unborn children have never had a stronger defender in the White House,” we are reminded of Erik Jansson, who ran the National Network to Prevent Birth Defects and helped to convene the founding meeting of Beyond Pesticides, and took on then-Administrator of EPA Anne Gorsuch, calling her a “baby killer” because of policies that allowed exposures to toxic chemicals—exposures that endangered children and fetuses. Those were harsh words in the 1980s even when the Reagan administration’s environmental and toxics policies were tied to elevated harm to people, and children in particular. In today’s world, scientists and medical doctors are regularly linking elevated death rates from coronavirus to the federal government’s inadequate coronavirus policy and its attack on science. And, they are pointing to those in charge. Policies and decisions under the Trump administration that threaten the health of children and the unborn include: COVID-19 misinformation. […]

(Beyond Pesticides, October 14, 2020) Exposure to certain endocrine disrupting pesticides increases the risk men, and Hispanic men in particular, will contract testicular cancer, according to research presented at the American Association for Cancer Research Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved. The data show that living near the use of the insecticide acephate presents the greatest cancer risk. “Testicular cancer rates have been rising for decades and are rising especially quickly among Hispanics in the United States,” said Scott Swartz, an MD candidate in University of California Berkeley-UCSF Joint Medical Program, to Healio. “Given that Hispanics are disproportionately exposed to many endocrine-disrupting pesticides in California, we were interested in investigating the potential effects of nearby endocrine-disrupting pesticide application on testicular cancer among Hispanics in California.” Using public health databases, researchers assessed a group of 381 men diagnosed with testicular cancer while 15 to 19 years old, during the years 1997-2011. This cohort was compared to a control group of 762 otherwise healthy men of similar age, race and ethnicity during the same time. California’s Pesticide Use Report system was used to analyze agricultural pesticide applications within 1.8 miles of a study […]

(Beyond Pesticides, October 2, 2020) The U.S. Environmental Protection Agency’s (EPA) September 22 announcement asserts that, “despite several years of study, the science addressing neurodevelopmental effects [of the insecticide chlorpyrifos] remains unresolved,” as reported in The New York Times. This conclusion contradicts both ample scientific evidence and the agency’s own findings. Beyond Pesticides has repeatedly advocated for a ban on the use of chlorpyrifos because of the grave risks it poses. This organophosphate pesticide is used on approximately 60 different crops, including almonds, cotton, citrus fruits, grapes, corn, broccoli, sugar beets, peaches, and nectarines. It is also commonly employed for mosquito-borne disease control, and on some kinds of managed turf, including golf courses. Exposure to the pesticide has been identified repeatedly as problematic. Most residential uses were taken off the market in 2000, after the manufacturer, DowDupont (now Corteva) was faced with EPA action. Chlorpyrifos is a cholinesterase inhibitor that binds irreversibly to the receptor sites of acetylcholinesterase (AChE), an enzyme that is critical to normal nerve impulse transmission. In so doing, chlorpyrifos inactivates the enzyme, damages the central and peripheral nervous systems, and disrupts neurological activity. The compound is associated with harmful reproductive, renal, hepatic, and endocrine disrupting effects, and most […]

(Beyond Pesticides, September 22, 2020) Use of the highly hazardous, endocrine disrupting weed killer atrazine is likely to expand following a decision made earlier this month by the U.S. Environmental Protection Agency (EPA). Under the guise of “regulatory certainty,” the agency is reapproving use of this notorious herbicide, as well as its cousins simazine and propazine in the triazine family of chemicals, with fewer safeguards for public health, particularly young children. Advocates are incensed by the decision and vow to continue to put pressure on the agency. “Use of this extremely dangerous pesticide should be banned, not expanded,” Nathan Donley, PhD, a senior scientist at the Center for Biological Diversity said in a press release. “This disgusting decision directly endangers the health of millions of Americans.” Beyond Pesticides has long argued against the continued use of the triazine herbicides, which includes atrazine. Triazines are well known to interfere with the body’s endocrine, or hormonal system. Disruptions within this delicately balanced process in the body can result in a range of ill health effects, including cancer, reproductive dysfunction, and developmental harm. These weedkillers interfere with the pituitary gland’s release of luteinizing hormones, which regulate the function of female ovaries and male gonads. In comments written by Beyond Pesticides to EPA, the organization notes, “Of the numerous adverse effects associated with this disruption, […]

(Beyond Pesticides, September 18, 2020) In late August, Consumer Reports magazine (CR) issued a report titled, “Stop Eating Pesticides,” which offers consumers a rating system CR developed and employed to help them “get the health benefits from fruits and vegetables while minimizing [the] risk from toxic chemicals.” In addition to providing its analysis and ratings of the pesticide risk of a variety of produce items, CR recommends eating organically grown and raised foods whenever possible. It also makes a host of recommendations on federal pesticide policies and emphasizes the importance of maintaining the integrity of the National Organic Standards (of the USDA-housed National Organic Program). Beyond Pesticides appreciates that this mainstream publication has arrived at many shared, science-based assessments of the risks of pesticides. That said, a wholesale transition to organic and regenerative agriculture — rather than making the public figure out which fruits and vegetables are “safer” or “less safe” — is the real answer to the health risks of pesticides in the food supply, according to Beyond Pesticides. The CR analysis used data from the U.S. Department of Agriculture’s (USDA’s) Pesticide Data Program for 2014–2018. Those pesticide residue data were compiled from tests of approximately 450 pesticides across 24,000 […]

(Beyond Pesticides, August 12, 2020) The herbicide atrazine can interfere with the health and reproduction of marsupials (including kangaroos and opossums) kangaroo, Virginia opossum, according to research published in the journal Reproduction, Fertility, and Development. Although the research focuses on the health of the Australian wallaby, the data is relevant for the only marsupial in the United States, the opossum. Unfortunately, the research is no surprise, as atrazine has a long history of displaying endocrine (hormone) disrupting properties, affecting sex and reproduction in a broad range of species. The study, under the auspices of University of Melbourne Animal Experimentation and Ethics Committee, exposed pregnant female adult wallabies to atrazine through gestation, birth, and lactation. Doses of the weedkiller were slightly higher than real world models, but according to researchers, “It is quite possible a wild animal could get such an exposure.” Researchers then euthanized the newborn wallabies to study atrazine’s effects. The gonads and phallus of young wallabies were analyzed for any physiological changes or impacts to gene expression. Researchers found changes to the gene expression necessary for basic function of the testis, and a significant reduction in phallus length. “These results demonstrate that [atrazine] exposure during gestation and lactation can […]

(Beyond Pesticides, August 7, 2020) Research out of the Silent Spring Institute identifies 28 registered pesticides linked with development of mammary gland tumors in animal studies. Study authors Bethsaida Cardona and Ruthann Rudel also report that many of the pesticides they investigated behave as endocrine disruptors; breast cancers in humans are significantly influenced by hormones generated by the endocrine system. The Environmental Protection Agency (EPA) acknowledges that nine of these 28 pesticide compounds cause mammary tumors, but dismisses the evidence of the other 19. The results of this research, published in the journal Molecular and Cellular Endocrinology, evince Beyond Pesticides’ long-standing argument that the risk assessment process used by EPA for its pesticide registration process is substantially inadequate to protect human health. The co-authors cite, as the catalyst for this research project, a Cape Cod resident’s outreach to the Silent Spring Institute several years ago, asking for information about the herbicide triclopyr because utility companies wanted to spray it on vegetation below local power lines. (The compound has also been used by the logging industry in the Pacific Northwest.) They reviewed more than 400 EPA pesticide documents on the health impacts of many registered pesticides for this research, conducted as part […]

(Beyond Pesticides, July 2, 2020) Exposure to low levels of endocrine-disrupting chemicals commonly in waterways, including pesticides, can impact future generations of major commercial fish, despite no direct exposure to the chemicals, according to research published in the journal Frontiers in Marine Science by Oregon State University (OSU) researchers. Many studies assess the acute or chronic health implications associated with endocrine disruptors on a single generation but lack information on multi-generational impacts that can provide vital information on the fundamental survivability or fitness of many species. This study highlights the significance of understanding the implications of endocrine disruptors, even at low levels of exposure, as parental exposure can have adverse epigenetic consequences for future generations. Kaley Major, a Ph.D. fellow at Oregon State University (OSU) and lead research author, explains, “What t[his] gets at is something your grandparents may have come into contact within their environment can still be affecting the overall structure of your DNA in your life today.” Endocrine disruptors are xenobiotics (i.e., chemical substances like toxic pesticides foreign to an organism or ecosystem). Past research shows exposures to endocrine-disrupting chemicals can adversely impact human, animal—and thus environmental—health, by altering the natural hormones in the body responsible for […]

(Beyond Pesticides, June 30, 2020) A review of scientific literature on the toxic effect of environmental contaminants—including pesticides—published in the journal Toxicological Science, “The Impact of Environmental Chemicals on the Gut Microbiome,” associates these chemicals to changes in the gut microbiome and other adverse health implications. The review, by researchers at the University of Illinois, looks at how environmental contaminants adversely effects and reinforce chemical disruption of the gut microbiome. It highlights the importance of evaluating how environmental contaminants, like pesticides, impact body regulation by gut microbiota. The study has significant implications for considerations that should be, but are not currently, a part of pesticide review and registration by the U.S. Environmental Protection Agency (EPA). Gut microbiota plays a crucial role in lifelong digestion, immune, and central nervous system regulation, as wells as other bodily functions. Through the gut biome, pesticide exposure can enhance or exacerbate, the adverse effects of additional environmental toxicants on the body. Since the gut microbiome shapes metabolism, it can mediate some toxic effects of environmental chemicals. However, with prolonged exposure to various environmental contaminants, critical chemical-induced changes may occur in the gut microbes, influencing adverse health outcomes. Karen Chiu, Ph.D., a graduate research fellow at the […]

(Beyond Pesticides, June 18, 2020) Residential exposure to household pesticide products increases the risk of developing symptoms associated with depression, according to a study published in Environmental Research by researchers at Medical College of Georgia—Augusta University, School of Medicine—Jinan University, and Guangzhou Center for Disease Control and Prevention (CDC), China. Research on pesticide-induced diseases commonly investigates pesticide exposure concerning the development of various physical illnesses, and previous studies show there are occupational risks of developing depression, especially in agriculture where pesticide use is rampant. However, there is a lack of information connecting pesticide exposure to the subsequent psychological (psychiatric) effects on the general population. Additionally, household pesticide exposure varies from occupational exposure via exposure frequency, duration, intensity, and type. This research highlights the significance of researching potential mental health effects resulting from pesticide exposure, especially as society tends to rank mental health risks second to physical health. The study’s scientists note, “Our results highlight the importance of the cautious use of household pesticides because the chronic effects of poisoning may contribute to an elevated risk of depression.”  According to the World Health Organization (WHO), depression affects 322 million people globally, with the number of diagnosed patients increasing by 18.4% from 2005 to 2015. Although the etiology of depression—and […]

(Beyond Pesticides, June 11, 2020) Researchers at North Carolina State University (NC State) and Duke University found that dogs can potentially operate as a sentinel, or indicator, species for environmental contaminate exposure – and subsequent diseases – in humans using silicone monitoring devices (i.e., wristbands, collars, etc.), according to research published in Environmental Science & Technology. Although scientists commonly use silicone devices to gauge organic contaminant exposure levels in epidemiological studies, the identification of chronic human diseases from pollutants remains challenging. Anthropoid (human) diseases can take many years to develop, even after initial contaminant exposure. However, dogs can develop comparable anthropomorphic diseases from susceptibility to the same environmental contaminants, but at a much quicker pace. This research highlights the significance of researching disease identification methods, mutual amid multiple species, to mitigate challenges surrounding long disease latency periods. Matthew Breen, Ph.D., professor of comparative oncology genetics at NC State, asserts, “If we develop ways to correlate dog disease with their exposures over time, it may allow human-health professionals to mitigate these exposures for both species. This study reinforces the concept of One Health, demonstrating that in addition to being our closest animal companions, our dogs are truly a sentinel species for health.” As […]

(Beyond Pesticides, June 2, 2020) During the April meeting of the National Organic Standards Board (NOSB), there was near-unanimous sentiment expressed by NOSB members and stakeholders that the failure of the National Organic Program at USDA to act on NOSB recommendations regarding so-called “inert” ingredients hurts organic producers and consumers and the environment. The NOSB has only one alternative left to force USDA action—denying relisting at the Fall meeting. Tell the National Organic Program and USDA Secretary Sonny Perdue to initiate action to begin NOSB review of “inerts” now. Dr. Asa Bradman, who summarized the issue for the NOSB at the Spring 2020 meeting, is an expert in environmental health, and as part of his day job, leads studies focusing on pesticides, flame retardants, metals, emerging pollutants, VOCs, indoor air quality and other contaminants. As he said at the meeting, “These are often active ingredients.” In fact, the ingredients not listed on a label of a pesticide product—which are not fully reviewed for their adverse effects—may be the most toxic chemicals in the formulation. Recent research, Toxicity of formulants and heavy metals in glyphosate-based herbicides and other pesticides (Toxicology Reports 5, 2018), by Defarge, de Vendômois, and Séralini demonstrates the need to […]

(Beyond Pesticides, April 20, 2020) As USDA takes public comments on its updated dietary guidelines, it important that sustainable, regenerative organic food production practices are an integral part. Since 1990, Congress has required an every-five-years review of its Dietary Guidelines — recommendations intended to promote public health and prevent chronic diseases. The next review and a draft updated version, the 2020–2025 Dietary Guidelines for Americans, is currently underway. USDA says that the dietary guidelines provide “information that helps Americans make healthy choices for themselves and their families.” In order to make healthy food choices, the guidelines must go beyond the traditional parameters to include how the food is produced. How food is produced affects the health of Americans not only as a result of the nutritional quality of the food, but also due to environmental contamination. Sign the petition to USDA and send a letter to Congress. Tell them that organic food must be emphasized in new dietary guidelines. Although research on the nutritional density of organic produce is equivocal, showing some higher levels of antioxidants, results are decidedly clear for animal products. Pastured organic animal products—including beef, lamb, pork, dairy, poultry, and eggs—have been shown to be superior to that of products of […]

(Beyond Pesticides, March 2, 2020) Deadline today! Tell EPA to Ban Atrazine; Protect Children and Frogs from this Endocrine Disrupting Pesticide. Atrazine, the second most-used herbicide in the U.S., is an insidious poison. Atrazine is known for producing developmental abnormalities in frogs. It also affects the endocrine system and reproductive biology of humans. In addition to its agricultural uses on corn, sorghum, and sugar cane, atrazine is also used on home lawns, school grounds, and parks, where exposure to children is common. Nontoxic alternatives are available for all of these uses. Act today, March 2. Sign the petition demanding that EPA ban atrazine and its cousins simazine and propazine. Act today! Beyond Pesticides will submit comments: Docket: EPA-HQ-OPP-2017-0750 (FRL-10002-92) Petition to EPA’s Office of Pesticide Programs: We have serious concerns with the proposed interim decisions on reregistration of three triazine pesticides: atrazine, simazine, and propazine. These triazines are highly mobile and persistent in the environment and have been linked to numerous adverse health and environmental effects which have motivated numerous public interest campaigns to ban their use in the U.S. as well as in Europe. The Draft Ecological Risk Assessments for the Registration Review of Atrazine, Simazine, and Propazine dated October 5, 2016 […]

(Beyond Pesticides, February 27, 2020) A new report finds that as birds and pollinators continue to decline, and chronic diseases remain on the rise, the global agrichemical industry is raking in billions of dollars from hazardous pesticides that contribute to these crises. A joint investigation from Unearthed and Public Eye finds that 35% of pesticide sales from the largest agrichemical corporations are made from the most toxic pesticides on the market. Pesticide production was a $57.6 billion market in 2018, according to the report. While the profits of the industry are privatized, the public health and environmental effects are broad. Studies conducted over the last decade show that the impacts of hazardous pesticide use dwarf the market for these chemicals. The impact of pesticides on public health results in a drag on the economy. Earlier this year, research from the New York University Grossman School of Medicine found that children’s exposure to organophosphate insecticides was estimated to result in over 26 million lost IQ points and over 110,000 cases of intellectual disability, totaling roughly $735 billion in economic costs each year. A 2019 study from the same scientists determined that endocrine disrupting chemicals, including organophosphates and organochlorine pesticides, were attributable […]

(Beyond Pesticides, February 11, 2020) A new study, published in the journal Cell Host & Microbe, homes in on the impact of the toxic herbicide atrazine on wasp gut microbiology and pesticide resistance. Intriguingly, researchers found that exposure to atrazine changed the composition of gut bacteria in individual wasps and shifts in gut flora were heritable. This study not only represents one of the first evolutionary studies on symbiont-mediated pesticide resistance, it also provides fodder for future research regarding the implications of exposure to xenobiotics (i.e., chemical substances like toxic pesticides foreign to an organism or ecosystem) for other gut bacteria hosts – such as honey bees and humans. Researchers utilized the hymenopteran insect model Nasonia vitripennis to analyze the effect of subtoxic exposure to atrazine across 36 generations. They reestablished a baseline of toxicity by experimenting with concentrations of atrazine to find the level at which 50% of the population died (LC50). During initial trials, some of the wasps were kept in a germ-free (GF) environment. The authors observed a higher mortality rate among the germ-free population, indicating that gut microbes assist with detoxification.   Early generations of wasps in the study received a field-realistic dose of atrazine (300 […]

(Beyond Pesticides, January 29, 2020) A study of male breast cancer (MBC) in Scotland reports an alarming, increasing trend of this rare disease – especially in agricultural areas. While only accounting for 1% of diagnosed breast cancer, MBC forms in the breast tissue of men and is often fatal because of delayed diagnosis and lack of research on male-specific treatment. The authors point to risk factors that include increased exposure to endocrine-disrupting chemicals, such as pesticides, and a need for further study. Researchers analyzed data from the Information Services Scotland database spanning from 1992-2017. Results showed that incidence of breast cancer in men rose with age, and that the total number and age-adjusted incidence of MBC increased in the last 25 years. Overall, the incidence rose by 38.5%. There was a total of 558 diagnoses in Scotland in the entire period. The trend is clearest in certain regions, including the North of Scotland and some rural areas. “Within the confines of this observational study, reasons for these regional differences are difficult to reconcile, but potential explanations are offered,” the authors write, “Exposure to environmental compounds that mimic oestrogens (so-called Endocrine-Disrupting Chemicals; (EDCs)) might be exacerbated in areas of higher agricultural […]