(Beyond Pesticides, February 19, 2016) Pesticide mixtures are more harmful than individual pesticides, according to a University of California, Los Angeles (UCLA) study that focuses on three commonly used fumigants — chloropicrin, Telone, and metam salts. The study also concludes that, while California law requires the Department of Pesticide Regulations (DPR) and county agricultural commissioners to assess these kinds of cumulative risks when regulating pesticides, they have so far failed to do so. The report, titled Exposure and Interaction — The Potential Health Impacts of Using Multiple Pesticides: A Case Study of Three Commonly Used Fumigants, was published by the Sustainable Technology and Policy Program, based in the UCLA School of Law and the UCLA Fielding School of Public Health. The case study of the three fumigants, which are commonly applied together in California on high value crops, such as strawberries, tomatoes, tree nuts, and stone fruits, finds that: These pesticides may interact to increase the health risk for California farm workers and residents, Workers and residents are regularly exposed to two or more of these pesticides simultaneously, and DPR does not regulate the application of multiple pesticides to prevent or decrease risks to human health, despite having authority to […]

(Beyond Pesticides, February 16, 2016) Last Thursday, officials reported that federal scientists for the U.S. Fish and Wildlife Service (FWS) are recommending follow up studies for a portion of the Wallkill River in Sussex County, NJ, in addition to five other national wildlife refuges in the Northeast that were previously found to contain small-mouth bass with intersex characteristics. A study conducted  by FWS and the U.S. Geological Survey (USGS) points out that smallmouth and largemouth bass are showing intersex features, but researchers have  not pinpointed the cause. Scientists hope a follow up study will provide answers. Intersex fish and other species are  characterized  by one sex exhibiting traits  of the opposite sex. In the case of the FWS/USGS study, researchers found testicular oocytes ””female eggs found inside male testicles””in male smallmouth and largemouth bass. The source of intersex effects  can be hard to pinpoint, but pesticides are often cited as a cause given that they widely pollute waterways that  fish populate. Those chemicals have properties that disrupt the endocrine system and affect the reproductive system, causing development issues such as testicular oocytes. According to the USGS press release for the study, “Estrogenic endocrine-disrupting chemicals are derived from a variety of […]

(Beyond Pesticides, February 12, 2015) A new study published last week asserts a viral epidemic driven by parasitic mites is contributing to the global decline in bees, problematically underplaying the significant impact that bee-toxic neonicotinoid insecticides have on pollinator populations, as supported by a growing body of scientific literature, especially findings that show bees’ increased vulnerability to parasites and viruses. Researchers of the study, titled “Deformed wing virus is a recent global epidemic in honeybees driven by Varroa mites” and published in the journal Science, conclude that the deformed wing virus (DWV), which is typically transmitted through its main vector, the Varroa mite, is globally distributed and recently spread from a common source, European honeybee Apis mellifera. Lead researcher Lena Bayer-Wilfert, PhD, of the University of Exeter, said European bees are at the heart of the global spread of what she calls a “double blow” for colonies. “This is clearly linked to the human movement of honey bee colonies around the globe,” she told BBC News. Co-researcher Professor Roger Butlin of the University of Sheffield said DWV was a major threat to honey bee populations across the world with the epidemic “driven by the trade and movement of honeybee colonies.” […]

(Beyond Pesticides, February 5, 2016) According to a report published earlier this week, Trends in glyphosate herbicide use in the United States and Globally, glyphosate, manufactured by Monsanto and known by its product name Roundup, is the most widely and heavily applied weed-killer in the history of chemical-intensive agriculture both in the U.S. and globally. Charles Benbrook, Ph.D., author of the study, which was published in the peer-reviewed journal Environmental Sciences Europe, reports that to date 18.9 billion pounds (8.6 billion kilograms) of glyphosate have been used globally, with an estimated 19% of the use coming from the U.S. The report also points out that glyphosate use has risen almost 15-fold since “Roundup Ready” genetically engineered crops (GE) were introduced in 1996. Dr. Benbrook’s research concludes that, “Genetically engineered herbicide-tolerant crops now account for about 56 % of global glyphosate use. In the U.S., no pesticide has come remotely close to such intensive and widespread use.” According to the report, two-thirds of the total volume of glyphosate applied in the U.S. from 1974 to 2014 has been sprayed in just the last 10  years. And, in 2014, enough glyphosate was sprayed to leave more than three-quarters of a pound of […]

(Beyond Pesticides, January 27, 2016) Last week the Senate Environment and Public Works Committee added an amendment to the Sportsman Act of 2015 that would remove important protections from pesticides sprayed into our nation’s waterways. After years of failed attempts to pass a version of the amendment as a stand-alone bill called the “Sensible Environmental Protection Act,” the latest attack against clean water was put forth by Senator Deb Fisher (R-NE), and passed by a committee vote of 12-8. It now moves to the Senate floor in a piece of bipartisan legislation. This amendment would reverse a 2009 federal court decision in National Cotton Council v. EPA that directed EPA to require permits from applicators who spray over “navigable waters,” as outlined in the Clean Water Act (CWA). The bill’s proponents claim that the need for water permits is duplicative, given that pesticide applicators also comply with the Federal Insecticide, Fungicide and Rodenticide Act (FIFRA), the law that requires applicators to follow instructions on pesticide labels. However, the fact is that CWA permits let authorities know what is sprayed and when it is sprayed, so that the public may know what chemicals are used in their waterways and the potential […]

(Beyond Pesticides, January 25, 2016) Monsanto filed a lawsuit in California last week seeking to prevent glyphosate, the main ingredient in its Roundup herbicide, from being added to California’s  list of known carcinogens under the state’s Safe Drinking Water and Toxic Enforcement Act of 1986 (Proposition 65). Glyphosate is  classified  as a probable carcinogen by the World Health Organization’s International Agency for the Research of Cancer (IARC) based on sufficient  evidence  of carcinogenicity in experimental animals. This is the highest level carcinogen based on laboratory animal studies  under  IARC’s rating system. California law requires the state to keep a list of cancer-causing chemicals to inform residents of their risks. California Office of Environmental Health Hazard Assessment (OEHHA) said in September that it planned to add glyphosate to the list after the World Health Organization’s International Agency for Research on Cancer (IARC) classified it as a probable human carcinogen last March. Monsanto has disputed the assessment, citing decades of studies deeming glyphosate safe, including a 2007 study by OEHHA that concluded the chemical was unlikely to cause cancer. The agrochemical company said it filed the suit against the state’s OEHHA, citing the agency’s acting director, Lauren Zeise, in California state court, […]

(Beyond Pesticides, December 18, 2015) One of the most likely causes for the population decline of smallmouth bass in the Susquehanna River are endocrine-disrupting compounds and herbicides, concludes a multi-agency, multi-year study of one of the most complex river systems in Pennsylvania. The Pennsylvania Department of Environmental Protection (DEP) and the Pennsylvania Fish and Boat Commission (PFBC), along with nearly 50 participants and six partner agencies, released findings on Monday that narrow the likely causes from an initial field of 14 candidates to two. PFBC also found that pathogens and parasites are probable contributing factors. Following a smallmouth bass (SMB) population crash in 2005, and additional observed maladies, such as tumors and lesions on SMB, the team used ground-breaking monitoring strategies to collect more than 30,000 water quality records annually, along with review of existing research to isolate the possible causes keeping young-of-the-year (YOY) SMB from growing to adulthood. The study provides evidence to what Beyond Pesticides suspected back in May, when PFBC confirmed that a rare malignant tumor was found for the first time on a SMB caught by an angler back in the summer of 2014. Though the findings at the time did not point to a specific […]

(Beyond Pesticides, December 11, 2015) Milk contaminated with the long-banned and toxic organochlorine pesticide heptachlor in Hawaii has been found  in the brains of men that were more likely to develop Parkinson’s disease, according to a new study. This study adds to a large body of evidence linking pesticide exposure to Parkinson’s disease. Researchers of the study, titled “Midlife milk consumption and substantia nigra neuron density at death” and published in the journal Neurology, collected milk intake data from 1965 to 1968 for 449 men aged 45-68 years withpostmortem examinations from 1992 to 2004. Neuron density was measured in an area of the brain called substantia nigra (SN). As Parkinson’s develops, cells are destroyed in certain parts of the brain stem, particularly in the SN, a crescent-shaped cell mass. Measurements of brain residues of heptachlor epoxide, a heptachlor metabolite that is persistent and more toxic than its parent chemical, were also taken. “Among those who drank the most milk, residues of heptachlor epoxide were found in 9 of 10 brains as compared to 63.4%…for those who consumed no milk,” the researchers wrote. Neuron density was lowest in subjects who consumed the highest amounts of milk. The researchers looked at milk […]

(Beyond Pesticides, December 10, 2015) Researchers at Pennsylvania State University (Penn State) and the Pennsylvania Association for Sustainable Agriculture published a study, which found that aerial drift of the herbicide dicamba adversely affects non-target plants and pollinator species. Dicamba is a chlorinated benzoic acid herbicide associated with neurotoxicity and reproductive effects. The study used alfalfa crops to track the flowering and floral visitation by insects, specifically pollinators, after applications of sublethal doses of dicamba. The researchers concluded, “Our results suggest that widespread non-target damage from these herbicides may adversely affect pollinator communities.” Because dicamba is “frequently responsible for sublethal, off-target damage” to plants and insects, Penn State researchers assessed the most common route of exposure: particle and vapor drift. In its  study, Effects of the Herbicide Dicamba on Nontarget Plants and Pollinator Visitation, the research team examined the crop species alfalfa (Medicago sativa), which requires insect pollination to produce seeds, and the native plant species common  boneset (Eupatorium perfoliatum), which is highly attractive to a wide range of pollinator species. The researchers applied a range of sublethal doses of dicamba to the plants, then tracked flowering and floral visitation by insect species. They identified the types of insects visiting the […]

(Beyond Pesticides, December 4, 2015) Home Depot, the world’s largest home-improvement chain, has announced that it will no longer use  neonicotinoid (neonic) pesticides (which have emerged as the leading class of pesticides responsible for bee declines) in  80 percent of its flowering plants, and that it will complete its phase-out in plants by 2018. This follows the announcement made by Lowe’s earlier this year to phase out the sale of products containing neonicotinoid pesticides within 48 months. On its Eco Options gardening page, Home Depot says the following: “Our live goods suppliers have reduced the number of plants that they treat with neonicotinoids, so that now over 80% of our flowering plants are not treated HomeDepotWinBPwith neonicotinoids. We will continue this decrease unless,  1) it is required by state or federal regulation, or  2) undisputed science proves that the use of neonicotinoids on our live goods does not have a lethal or sub lethal effect on pollinators. Otherwise we will have a complete phase-out of neonicotinoid use on our live goods by the end of 2018.” “It’s important that retailers begin to make the switch toward safer products for bees, butterflies, and other beneficial insects,” said Jay Feldman, executive director […]

(Beyond Pesticides, November 23, 2015) Commonly-used pesticides can impact aquatic species over multiple weeks, even when chemicals are no longer detectable in water nor  monitored by regulators, according to new research. The study, titled A long-term assessment of pesticide mixture effects on aquatic invertebrate communities,  published in the journal Environmental Toxicology and Chemistry, investigates the long-term effects on aquatic invertebrate communities of commonly-used insecticides: two pyrethroids (permethrin and lambda-cyhalothrin) and an organophosphate (chlorpyrifos). Pesticide applications were based on environmentally relevant concentrations and lethal concentrations (a concentration required to kill a certain percentage of animals tested) ranging from 10% (LC10) to 50% (LC50). Researchers made repeat applications in order to mimic runoff events in a multiple grower or homeowner watershed. The results indicate that insecticide mixtures continue to impact natural systems over multiple weeks, even when bound to particles and no longer detectable in water. Combinations of indirect and direct effects caused consequences across the food chain. Pyrethroids rapidly dissipated from the water column, whereas chlorpyrifos was detectable even six weeks after application. “The effects we observed indicate that many species were affected at a sublethal level,” said Simone Hasenbein, Ph.D., lead author of the study tells Phys.org. “Thus, populations exposed […]

(Beyond Pesticides, November 18, 2015) Last week, the European Union’s (EU) European Food Safety Agency (EFSA) announced its determination that the popular herbicide glyphosate is “unlikely to pose a carcinogenic hazard to humans.” This is in direct contrast with findings released  earlier this year by  the World Health Organization’s (WHO) International Agency for Research on Cancer (IARC), which classified glyphosate a ”˜probable carcinogen.’  However, these seemingly conflicting conclusions from these premier scientific agencies are put into perspective by knowing that EFSA’s report is limited in that it reviewed glyphosate alone, unlike IARC which reviewed glyphosate and its formulated products (Monsanto’s Roundup) which are more relevant for evaluating risks to human health. In light of the March 2015 IARC findings —listing glyphosate as a probable carcinogen due to  sufficient evidence of carcinogenicity  based on laboratory studies, the European Commission requested EFSA consider glyphosate’s potential carcinogenicity. In its report released November 12, 2015, EFSA concludes that “glyphosate is unlikely to pose a carcinogenic hazard to humans and the evidence does not support classification with regard to its carcinogenic potential..” However, the agency notes that there are “several reasons explaining the diverging views” from IARC’s earlier conclusion. The most important difference is that […]

(Beyond Pesticides, November 16, 2015) Bayer CropScience, the manufacturer of neonicotinoid pesticides that are linked to severe decline in pollinator populations, is expected to pay fines to multiple countries in Europe for wine grape damages associated with another of its pesticides. Citing “atypical symptoms” resulting from the use of a relatively new fungicide, Bayer initially sent out a warning to wine growers to cease use of their product. Now, Bayer is collecting data and assessing how much it will offer to wine growers for the damages its product has caused. European grape growers, including vineyards in Austria, France, Germany, Italy, Luxembourg and Switzerland, have reported deformed leaves and lower yields after using Moon Privilege, also known as Luna Privilege in some markets, from the German company’s CropScience unit. In Switzerland, losses are estimated at 80 million Swiss francs ($83.73 million), as reported by marketing group Swiss Wine to Reuters. Swiss Wine’s general secretary estimates harvest losses totaling 6.65 million kilos (14 million pounds) of grapes in 2015, or about  4.85 percent of 2014’s crop. It is also estimated that wine makers have lost approximately six million bottles of wine, with  Pinot Noir grapes and Chasselas, a white wine grape, hardest […]

(Beyond Pesticides November 4, 2015) On Monday, the Center for Biological Diversity, the Center for Environmental Health, El Quinto Sol de America, Californians for Pesticide Reform, the Center for Food Safety and the Pesticide Action Network released a report with findings that that more than half of the commercial glyphosate sprayed in California is applied in the state’s eight most impoverished counties. Glyphosate is a phosphanoglycine herbicide that inhibits an enzyme essential to plant growth.  Commonly known as Roundup, glyphosate is classified as a probable carcinogen by the World Health Organization’s International Agency for the Research of Cancer (IARC), based on sufficient evidence of carcinogenicity in experimental animals, and is currently under review to receive a similar designation from the state under California’s Safe Drinking Water and Toxic Enforcement Act of 1986 (Proposition 65). The report,  Lost in the Mist:  How Glyphosate Use Disproportionately Threatens California’s Most Impoverished Counties, found that 54 percent of glyphosate spraying in California is applied in eight counties, many of which are located in the southern part of the Central Valley. The analysis finds that the populations in these counties are predominantly Hispanic or Latino, indicating that glyphosate use in California is distributed unequally along […]

(Beyond Pesticides, October 26, 2015) Last week, Pop Weaver, the second largest popcorn supplier in the country, released an official statement on its commitment to “removing 50 percent of its neonicotinoid usage in 2016, 75 percent in 2017, with a long-term commitment of further reducing usage by working with agricultural universities and those companies supplying neonicotinoids to the seed industry.” Widely-used neonicotinoids (neonics), which as systemic chemicals move through a plant’s vascular system and express poison through pollen, nectar, and guttation droplets, have been identified in multiple  peer-reviewed studies  and by beekeepers  as the major contributing factor in bee decline. This commitment is a response to a campaign led by Center for Food Safety (CFS), which asked citizens to sign a petition asking Pop Weaver, and other large popcorn suppliers, to protect bees and other pollinators by phasing out the use of neonicotinoid-coated corn seed. Over 37,000 people have signed their petition. Americans eat, on average, 17.3 billion quarts of popcorn each year; each American eats about 68 quarts. According to CFS, there are roughly 40 insecticides currently registered for use as an active chemical on popcorn, including 3 bee-toxic neonicotinoid chemicals: clothianidin, thiamethoxam, and imidacloprid. Between  79 and 100 […]

(Beyond Pesticides, October 23, 2015) Tests on produce collected by California’s Department of Pesticide Regulation (CDPR) for 2014 show high levels of  illegal toxic pesticide residues. The CDPR report found 1 percent of produce containing an excess amount of pesticide residues, and an additional 5.5 percent of produce tested contained illegal residues of pesticides that are not allowed for use on that product. Additionally, the data shows residues of a banned  chemical, which was taken off the market  over 20 years in the U.S. due to health concerns related to farmworker exposure. These findings showcase issues related to  system-wide failure in  enforcement. Advocates stress that violations may continue to occur due to inadequacies in regulations governing enforcement authorities, which include warnings or low fines for violators. In raising concerns about the safety of food grown with chemical-intensive methods, advocates point to the need to expand the transition to organic agriculture for better protection of public health and safety. The highest percentage of illegal pesticides was found on cactus pads and cactus fruit imported from Mexico. Some of the other tainted fruit and vegetables include limes, papaya, summer squash, tomatillos, chili peppers, and tomatoes, also from Mexico, ginger imported from China, […]

(Beyond Pesticides, October 9, 2015) Last week, the Environmental Protection Agency (EPA) released preliminary human health and ecological risk assessments for seven organophosphate pesticides (OPs) and announced the public open comment period for those chemicals. These risk assessments come as a result of the required periodic registration review, as required by  the Federal Insecticide, Fungicides, and Rodenticide Act. In general, OPs are highly toxic and many have been voluntarily removed from the market, considerably restricted, or denied reregistration. Unfortunately, EPA continues to rely on risk mitigation for individual OPs instead of phasing them out altogether. Seven OPs ­ ­—dimethoate, dictrotophos, chloyrophos-methyl, tribufos, terbufos, profenofors, and ethoprop—are among the first wave of chemicals whose preliminary risk assessments have been completed under the registration review program. Each of these was found by EPA to inhibit the enzyme acetylcholine esterase (AchE), which ultimately leads to neurotoxic  central nervous system effects. This information is not new, however. In 2012, University College London found long-term low-level exposure to OPs produces lasting damage to neurological and cognitive functions. In 2013, at least 25 children died after eating school lunches contaminated by OPs. One OP in particular, chlorpyrifos, chlorpyrifos (Dursban), is currently under petition for the same […]

(Beyond Pesticides, October 6, 2015) Last week, the International Federation of Gynecology and Obstetrics (FIGO) released a statement encouraging broad-based policy measures that prevent exposure to toxic environmental chemicals. “The global health and economic burden related to toxic environmental chemicals is in excess of millions of deaths and billions of dollars every year,” the report unequivocally states. FIGO’s statement follows a similar call to action from the American College of Obstetricians and Gynecologists in 2013 and the American Academy of Pediatrics in 2012. The piece lays out broad themes surrounding exposure to toxic chemicals, including issues of environmental justice, prenatal exposure and subsequent health effects, and overall global health and economic burden. Based on these impacts, several recommendations are submitted for obstetricians, gynecologists, midwives, women’s health nurse practitioners, nurses, and other health professionals to follow to achieve a goal of “prevention for all.” FIGO highlights how people of low-income, particularly in poverty-stricken countries, bare a higher burden of toxic exposure than richer nations. “[A]t every stage of development, the consequences of exposure to toxic chemicals —including morbidity and mortality, loss of family income and productivity, and environmental degradation— are disproportionately borne by people with low incomes,” the piece states. FIGO […]

(Beyond Pesticides, September 18, 2015) Glyphosate’s harmful effects continue to accumulate, this time with evidence pointing to toxic and sublethal effects on bees. According to a new study conducted by German and Argentinian researchers, honey bees exposed to low levels of glyphosate have a hard time returning home. Glyphosate, the  controversial and toxic active ingredient in Monsanto’s Roundup, is an herbicide widely used on genetically-engineered (GE) crops as well as on parks and golf courses, for control of weeds and grasses. Along with neonicotinoids, which have been linked to worldwide bee decline by a growing body of science, glyphosate is just another chemical in the toxic mixture that bees and other non-target organisms are constantly exposed to in the environment. In the study, titled “Effects of sublethal doses of glyphosate on honeybee navigation” and published in the Journal of Experimental Biology, researchers evaluate the effects of recommended concentrations of glyphosate used in agricultural settings on honey bee navigation and found that a single exposure to a concentration of glyphosate within this range delays the return of the foraging honey bee to the hive. Flight trajectories were also affected after successive exposure to the herbicide, suggesting that the spatial learning process […]

(Beyond Pesticides, September 11, 2015) On Thursday, the Ninth Circuit Court of Appeals unequivocally rejected the U.S. Environmental Protection Agency’s (EPA) unconditional registration of the systemic and bee-toxic pesticide sulfoxaflor. The Court concluded that EPA violated federal law and its own regulations when it approved sulfoxaflor without reliable studies regarding the impact that the insecticide would have on honey bee colonies. The Court vacated EPA’s unconditional registration of the chemical, meaning that sulfoxaflor may no longer be used in the U.S. However, while the decision is good news for now, it still leaves the door open for sulfoxaflor’s future use once EPA obtains the necessary information regarding impacts to honey bees and re-approves the insecticide in accordance with law. The case is Pollinator Stewardship Council, American Honey Producers Association, National Honey Bee Advisory Board, American Beekeeping Federation, Thomas Smith, Bret Adee, Jeff Anderson v. U.S. EPA (9th Circuit U.S. Court of Appeals,  No. 13-7234). Dow AgroSciences (a Dow Chemical company)  joined  the case as an intervenor to support EPA. EPA initially proposed to conditionally register sulfoxaflor and requested additional studies to address gaps in the data regarding the pesticide’s effects on bees. A few months later, however, EPA unconditionally registered […]

(Beyond Pesticides, September 10, 2015) Last week, California Environmental Protection Agency’s Office of Environmental Health Hazard Assessment (OEHHA) announced that it intended to list glyphosate (Roundup) and three other chemicals as cancer-causing chemicals under California’s  Safe Drinking Water and Toxic Enforcement Act of 1986 (Proposition 65). Glyphosate  is a phosphanoglycine herbicide that inhibits an enzyme essential to plant growth. Under California law, Proposition 65 requires that certain substances identified by the International View postAgency for Research on Cancer (IARC) be listed as known cancer-causing chemicals. In March, a study by the IARC classified glyphosate as a Group 2A material, which means that the chemical is carcinogenic based on sufficient evidence of carcinogenicity in experimental animals. The agency considered the findings from an EPA Scientific Advisory Panel report, along with several recent studies in making its conclusion. However, industry supporters of glyphosate all over the globe are conducting their own studies to attempt to prove that it is not a carcinogen. These studies, like one by German Federal Institute for Risk Assessments (BfR), are based almost solely on industry science and classified industry reports, each of which might not consider critical variables. With more glyphosate-focused studies being released, the growing evidence […]

(Beyond Pesticides, September 4, 2015) Research into neonicotinoid insecticides, a class of bee-toxic chemicals, and their effects on bees, needs to be more comprehensive in order to better reflect their global use, concludes a recent review of the current literature. The authors of the review state that despite considerable research efforts, there are still significant knowledge gaps concerning the impacts of neonicotinoids on bees. Since 2006, honey bees and other pollinators in the U.S. and throughout the world have experienced ongoing and rapid population declines. The science has become increasingly clear that pesticides (especially the  neonicotinoid class of insecticides), either acting individually or synergistically, play a critical role in the ongoing decline of honey bees and wild pollinators. Neonicotinoids can be persistent in the environment, and have the ability to translocate into the pollen and nectar of treated plants. The systematic review, titled Neonicotinoid Insecticides and Their Impacts on Bees: A Systematic Review of Research Approaches and Identification of Knowledge Gaps  and published in the journal PLoS ONE, took a look at over 200 primary research studies in order to identify knowledge gaps. While there is a growing body of science examining the impacts of neonicotinoid use, knowledge gaps need […]

(Beyond Pesticides, September 1, 2015) A  research study published in the journal Environmental Health  links chronic, ultra-low dose exposure to glyphosate in drinking water to adverse impacts on the health of liver and kidneys. The study, Transcriptome profile analysis reflects rat liver and kidney damage following chronic ultra-low dose Roundup exposure, is the latest in a string of data showing unacceptable risks resulting from exposure to glyphosate and products formulated with the chemical, like Monsanto’s Roundup. Researchers conducted the study by exposing rats to minute (0.1 parts per billion) doses of Roundup in drinking water for a period of 2 years. After noting tissue damage and biochemical changes in the blood and urine of exposed animals that was indicative of organ damage, the authors attempted to confirm their findings by analyzing changes in gene expression within liver and kidneys. Of 4,447 gene transcript clusters analyzed by scientists, 4,224 showed some alteration. Compared to non-exposed rats, “[t]here were more than 4,000 genes in the liver and kidneys whose levels of expression had changed,” said Michael Antoniou, PhD, senior author of the study to Environmental Health News. Authors indicate that the changes in gene expression observed in the study are associated with […]