(Beyond Pesticides, September 17, 2021) Against the backdrop of what The New York Times in 2018 called the “insect apocalypse,” and the dire plight of pollinators in particular, Friends of the Earth (FOE) recently issued its retailer scorecard, which benchmarks “25 of the largest U.S. grocery stores on pesticides, organic offerings and pollinator health”— with the vast majority of retailers failing to protect pollinators. FOE reporting shows some, but far too slow and anemic, progress by corporate actors in enacting pollinator- and bee-friendly policies across both retail sites and supply chains. Such policies, to be genuinely effective and protective of pollinators (and human health), would eliminate or at least dramatically reduce the presence of pesticides in the food supply. The path out of the chemical pesticide quagmire is organic: companies must do more to move suppliers to organic, regenerative production practices, and EPA should be pulling these toxic compounds from the market. Tracking the pollinator policies and enforcement activities of various huge companies yields a useful barometer in monitoring the travel of pesticides to the consumer. Yet the results in the FOE scorecard — e.g., only two of those 25 retailers scored even in the “B” range, and 21 scored […]

(Beyond Pesticides, September 15, 2021) Toxic pesticide use, and glyphosate in particular, degrades the health of freshwater ecosystems by harming species that form the basis of aquatic food chains, according to research published by scientists at McGill University. In a series of studies, scientists investigated how freshwater bacteria and zooplankton were affected by varying levels the weed killer glyphosate, the neonicotinoid insecticide imidacloprid, and nutrient levels. “Because plankton form the foundation of the food chain in freshwater ecosystems, it is very important to understand how plankton communities respond to widely used pesticides,” said Jesse Shapiro, PhD, an Associate Professor in McGill’s Department of Microbiology and Immunology. “Our research shows that the structure of these communities can be impaired under currently acceptable North American water quality guidelines.” Two separate experiments were conducted under similar conditions in order to properly investigate the effects of pesticide exposure on either zooplankton or freshwater bacteria. For both studies, target species were exposed to varying rates of glyphosate, imidacloprid, or both chemicals at either high or low water nutrient levels. Researchers conducted this study by establishing a series of outdoor experimental ponds, intended to mimic freshwater ecosystems by using Lake water and evenly distributing organisms throughout […]

(Beyond Pesticides, September 8, 2021) The U.S. Environmental Protection Agency (EPA) last month released a long-overdue biological evaluation of the three most commonly used neonicotinoid (neonic) insecticides, finding that the chemicals are likely to adversely affect the lion’s share of endangered species and their habitat. While the public may be most familiar with the damage neonics cause to pollinator populations, EPA’s evaluation highlights the widespread, indiscriminate harm scientists throughout the world have been sounding the alarm about for years. Advocates say the findings make it clear that neonicotinoids must be immediately banned from use. Under the Endangered Species Act (ESA), EPA is required to consult with federal wildlife agencies and conduct a biological evaluation of the impacts a pesticide may have on endangered species and their habitats, prior to the agency formally registering the pesticide. This almost never happens. EPA regularly fails to conduct this evaluation, requiring environmental and conservation organizations to sue the agency in order to force compliance with the law.   EPA has been subject to a number of legal challenges over the last decade for its failure to comply with ESA when it registered neonics pesticides. In 2019, Ellis v Housenger (EPA), a lawsuit filed by […]

(Beyond Pesticides, July 16, 2021) Recently published research reviews the 2013 Wilsonville, Oregon mass bumblebee die-off from application of the neonicotinoid dinotefuran on 55 linden trees in a big-box-store parking lot. In that single event, the research paper (published in Environmental Entomology) estimates between 45,830 and 107,470 bumblebees from some 289–596 colonies were killed. Reporting on the new study, by Entomology Today, quotes primary conclusions of the co-authors: “Our study underscores the lethal impact of the neonicotinoid pesticide dinotefuran on pollinating insect populations,” and, “It is likely that the vast majority of mass pesticide kills of beneficial insects across other environments go unnoticed and unreported.” As Beyond Pesticides has chronicled, the U.S. and the world are undergoing a pollinator crisis, caused in significant part by agricultural pesticides. Dinotefuran, the neonicotinoid (neonic) that killed those Oregon bumblebees, is used against fleas, thrips, tree-boring caterpillars, emerald ash borers, hemlock woolly adelgids, and in the Oregon case, aphids. Entomology Today (ET) notes that the timing of this particular application could not have been worse: it happened on a warm day when the linden trees were in full flower and the bees out in force. Ironically, it occurred during Nation Pollinator Week. ET pens a […]

(Beyond Pesticides, July 13, 2021) Bumblebees exposed to pesticides and pathogens display changes in gene expression that can be pinpointed and analyzed by cutting edge research tools, according to scientists at York university, who utilized the new technique in a study published in Molecular Ecology. This form of next-generation gene sequencing is part of a growing field of science known as conservation genomics, in which entire animal genomes are sequenced to determine conservation problems. “Next-generation sequencing is a totally new way to think about why bees are declining, which could revolutionize conservation biology,” says study coauthor Amro Zayed, PhD, associate professor in biology at York. “We’re looking directly at bee tissues  to try and get clues to the stressors that are affecting this bee. I think this is a gamechanger for sure. With a single study, we are able to implicate a couple of really obvious things we’ve talked about for years – pathogens and pesticides – in the case of Bombus terricola.” Researchers focused on Bombus terricola – the yellow banded bumblebee, as its range has declined significantly over the last two decades. The bumblebee was once common throughout the eastern and midwestern part of the U.S. and Canada, […]

(Beyond Pesticides, June 24, 2021) This Pollinator Week 2021, U.S. Representatives Earl Blumenauer (D-OR) and Jim McGovern (D-MA) are reintroducing the Saving America’s Pollinators Act (SAPA) in an effort to reverse ongoing declines in wild and managed pollinators. SAPA uses the latest scientific research and perspectives to ensure that pollinators are protected. The bill suspends the use of neonicotinoids and other pesticides harmful to bees and other pollinators until an independent board of experts determine that they are safe to use, based on strong scientific assessment. “Without our world’s pollinators, the world would be a very different place. These bees, butterflies, hummingbirds, and other creatures are essential elements of our food system. Losing them means we risk losing the very food we put on our table,” said Rep. Blumenauer. “We must use every tool at our disposal to provide pollinators with much-needed relief from bee-toxic pesticides and monitor their populations to ensure their health and survival.”  Neonicotinoids are systemic pesticides; once applied to a seed or sprayed on a plant they make their way into the pollen, nectar and dew droplets that plants produce and pollinators feed upon. Exposure impairs pollinator navigation, foraging, and learning behavior, and also suppresses their […]

(Beyond Pesticides, June 23, 2021) Small streams are prone to excessively high levels of pesticide contamination that are even more hazardous than once thought, according to a pilot study generated by a team of German researchers. The results indicate significant risks for the health of aquatic ecosystems and should be used as evidence for establishing greater protections from toxic pesticide use, researchers say. With many aquatic benchmarks set by the U.S. Environmental Protection Agency lower than those established in Germany and the European Union, and evidence of widespread pesticide contamination in America’s waterways, the study could have even greater weight for for U.S. regulatory agencies’ deficiencies. Scientists established monitoring sites at more than 100 streams throughout Germany over the course of two years. Most sites were established near farm fields, where chemical farmers will use highly toxic pesticides than often make their way into local waterways. Streams were monitored for pesticide concentrations, with particular eye to whether they met the country’s regulatory acceptable concentration (RAC value) in a given water body. The RAC value is intended to be the highest level at which there will be no adverse effects on aquatic life, however these regulatory levels often do not correspond […]

(Beyond Pesticides, June 18, 2021) As the U.S. Environmental Protection Agency (EPA) continues to drag its feet on protective regulation of neonicotinoid pesticides, states continue to step up to restrict their use. In April, the Maine legislature passed, and Governor Janet Mills has now signed, a new law that will prohibit use of neonicotinoid pesticides with the “active ingredient[s] dinotefuran, clothianidin, imidacloprid or thiamethoxam used for application in outdoor residential landscapes such as on lawn, turf or ornamental vegetation” [links by Beyond Pesticides]. Though short of an outright ban, this law is a solid step forward for Maine in reining in use of these compounds, which are neurotoxicants widely implicated in pollinator (and other insect, bird, and mammal) harms or declines. Until a federal ban happens, Beyond Pesticides offers guidance on avoiding use of neonicotinoid pesticides through its fact sheet, Managing Pests Safely Without Neonicotinoids, and its Bee Protective web pages. This new Maine law does, however, include exemptions for wood preservation, indoor pest control, use on pets, treatment of structure foundations, and controlling invasive insect pests, such as the Asian long-horned beetle, emerald ash borer, and hemlock wooly adelgid. The statute leaves other large loopholes that will permit continued use […]

(Beyond Pesticides, May 11, 2021) Last week, multinational agrichemical company Bayer Cropscience lost its bid to overturn a 2018 ban on bee-toxic neonicotinoids throughout the European Union. The ruling from the European Court of Justice rejected all grounds on which the company filed its appeal, noting, “It must be held that the arguments put forward by Bayer CropScience cannot, in any event, succeed.” In denying the appeal, the court ruled Bayer responsible for paying its own legal fees, as well as the fees of environmental organizations that intervened to defend the ban. Environmental groups are applauding the ruling, as it reinforces several important aspects of the EU’s pesticide policy that favor greater public health and environmental protections. In an interview with EURACTIV, policy officer Martin Dermine at Pesticide Action Network Europe notes that the decision provides more leeway for pesticide regulators to consider new scientific evidence on pesticide hazards. “More than that,” he told EURACTIV, “the Court confirms the definition of the precautionary principle:  in case of doubts on the toxicity of a pesticide, the European Commission is entitled to ban it.” Pesticide regulators in Europe began restricting neonicotinoids in 2013, when a continent-wide moratorium was put in place based […]

(Beyond Pesticides, April 16, 2021) Recent research, published in Environmental Pollution in late 2020, examines levels and persistence of pesticide pollution in recreational lakes. The study finds: (1) concentrations of the neonicotinoid imidacloprid at levels exceeding ecotoxicity limits for aquatic invertebrates in a recreational lake that receives predominately urban runoff, and (2) that pesticide residues persist in the studied lakes throughout the growing season. Based on their findings, the scientists emphasized the importance of stricter regulation of insecticide compounds, and of better education about their impacts. Beyond Pesticides maintains that neonicotinoid pesticides should be banned for several reasons, not least of which is the extreme damage they cause to pollinators. The goal of the study was to evaluate potential ecosystem exposure to pesticide contamination in Midwestern recreational lakes, as well as the persistence of pesticide residues in those water bodies over the course of the growing season. Study authors hypothesized that watersheds with significant agricultural land uses would have higher concentrations of pesticides compared to largely urban and herbaceous watersheds. This research, out of the University of Nebraska–Lincoln and the University of Kentucky, looked to evaluate the occurrence of neonicotinoid and organothiophosphate insecticides, and some fungicides, in three lakes with differing […]

(Beyond Pesticides, April 13, 2021) A new study is making it increasingly clear that current laws are not protecting wild, ground nesting bees from the hazards of neonicotinoid insecticides. According to research conducted under a grant from the U.S. Department of Agriculture’s Sustainable Agriculture Research and Education (SARE) projects, Blue Orchard Mason Bees (Osima spp) are at particular risk from pesticide-contaminated soil they use to create their nest. Authors of the study note that with honey bees already in decline, pollination services provided wild managed bees like Mason bees are growing in importance. “Wild bees such as Osmia are becoming increasingly popular as managed pollinators in many systems, as there is growing concern that honeybees may not be able to continue to meet the increasing demands of agricultural pollination if these trends continue,” the study reads. The study looked at three overarching threats to mason bee populations, aiming to identify risks from pesticide contaminated soil used as a nest, effects on larvae exposed to contaminated soil, and whether female mason bees could determine the difference between contaminated and uncontaminated soil. “Imidacloprid is a neonicotinoid, which is a group of pesticides that are highly toxic to bees,” said Christine Fortuin, PhD, […]

(Beyond Pesticides, April 8, 2021) Pesticide use threatens aquatic and terrestrial invertebrates and plants more than ever, despite declining chemical use and implementation of genetically engineered (GE) crops in the U.S., according to a University Koblenz-Landau, Germany study. Since the publication of Rachel Carson’s Silent Spring (1962), many environmental agencies have banned the use of pesticides like organochlorines, organophosphates, and carbamates for their devastating toxic—sometimes lethal—effects, particularly on vertebrates, including humans. However, this ban created a pathway for a new generation of pesticides (e.g., neonicotinoids, pyrethroids) to take hold. Although these pesticides are more target-specific, requiring lower chemical concentrations for effectiveness, they have over double the toxic effects on invertebrates, like pollinators.  Invertebrates and plants are vital for ecosystem function, offering various services, from decomposition to supporting the food web. Furthermore, invertebrates and plants can act as indicator species (bioindicators) that scientists can observe for the presence and impact of environmental changes and stressors. Therefore, reductions in invertebrate and plant life have implications for ecosystem health that can put human well-being at risk. Study lead author Ralf Schulz, PH.D., notes, “[This study] challenge[s] the claims of decreasing environmental impact of chemical pesticides in both conventional and GM [genetically modified or genetically engineered (GE)] crops and […]

(Beyond Pesticides, March 29, 2021) New data on the hazards of neonicotinoid insecticides calls for urgent regulatory action. The same pesticides that are linked to the worldwide decline of insect pollinators also present significant risks to their avian counterparts, hummingbirds. Widely known for their nectar-fueled hovering flight powered by wings beating up to 80 times per second, hummingbirds display unique reactions to toxic pesticides. Research by scientists at the University of Toronto finds that hummingbirds exposed to systemic neonicotinoid insecticides for even a short period of time can disrupt the high-powered metabolism of this important and charismatic animal. Tell EPA and Congress to save the hummingbirds by suspending use of neonicotinoid insecticides and supporting the transition to organic practices. While hovering, a hummingbird consumes calories faster than any other bird or mammal. That’s why the finding that exposure to the neonicotinoid insecticide imidacloprid slows metabolism up to 25% is so disturbing. Systemic pesticides like imidacloprid and other neonics are transported throughout the plant, including nectar. Findings on the danger neonicotinoids pose to hummingbirds decades after the chemicals were first permitted to be used in the environment, and by independent scientists, not regulatory agencies, is indicative of a regulatory approach that fails […]

(Beyond Pesticides, March 10, 2021) Deer populations throughout the state of Minnesota are contaminated with neonicotinoid insecticides, according to preliminary results published earlier this month by the Minnesota Department of Natural Resources (MDNR). Although neonicotinoids are mostly known for contributing to the decline of pollinator populations, like most pesticides brought to market with approval of an inadequate U.S. regulatory review process, there are considerable uncertainties on its impacts after it is released into the environment. As scientists continue to discover novel harms from the use of these systemic insecticides, advocates say it becomes increasingly important to eliminate their use, and take preventive, precautionary measures to ensure similar patterns do not emerge in the future. MDNR launched its testing project on the state’s deer population in Fall 2019, after a study published by researchers at South Dakota State University found harmful impacts on white-tail deer. The neonicotinoid imidacloprid was found to reduce the body weight and metabolism of white tailed deer and increase the rate of birth defects and mortality in fawns. The state asked deer hunters to send them the spleens they harvested from wild deer. “We wanted to know if wild deer in natural settings are being exposed to neonics and […]

(Beyond Pesticides, March 2, 2021) Populations of solitary ground nesting bees decline after exposure to neonicotinoid insecticides, according to a study published in Scientific Reports late last month. In addition to ground-nesting bees, neonicotinoids have been shown to harm butterflies, hummingbirds, songbirds, aquatic species and mammals, including humans. As independent science continues to look beyond the effects of these systemic chemicals on honey and bumblebees, advocates maintain that it has become increasingly clear that the high hazards presented by neonicotinoids necessitate their complete elimination. “Farmers need to protect their crops from pests, but they also absolutely need to protect pollinators from the unintended effects of pesticides,” said study coauthor Susan Willis Chan, PhD. “The data on this particular [neonicotinoid] product are so clear that there’s really no question about what has to happen. We have to find something else.” Researchers focused their effort investigating how various systemic pesticides effect the hoary squash bee (Eucera pruinosa), a ground nesting bee found throughout North America that feeds entirely on pollen from cucurbits (including squash, cucumber, pumpkin, gourds, etc). The hoary squash bee provides essential pollinator services for these crops throughout the U.S. and Canada. Neonicotinoids and other systemic insecticides are often applied […]

(Beyond Pesticides, February 23, 2021) The same pesticides implicated in the worldwide decline of insect pollinators also present significant risks to their avian counterparts, hummingbirds. Well known for their nectar-fueled hovering flight powered by wings beating over 50 times per second, hummingbirds display unique reactions to toxic pesticides. Research by scientists at the University of Toronto finds that hummingbirds exposed to systemic neonicotinoid insecticides for even a short period of time can disrupt the high-powered metabolism of this important and charismatic animal. Scientists began their experiment by trapping 23 wild ruby-throated hummingbirds and housing them in an animal care facility. One group of birds acted as a control and received no pesticide exposure, while the rest were assigned either low, middle, or high exposure (1 part per million [ppm], 2ppm, and 2.5ppm, respectively) to the neonicotinoid imidacloprid. Scientists determined these amounts based upon probable nectar contamination in the real world. The pesticide was incorporated into the sugar solution provided to the birds over the course of three days. Within two hours of exposure to the pesticides, hummingbird metabolism dropped significantly. While the control group increased energy expenditure between 1% to 7%, the low exposed group displayed a 6% average decline, […]

(Beyond Pesticides, February 2, 2021) The U.S. Environmental Protection Agency (EPA) will evaluate the effect of the neonicotinoid insecticide imidacloprid on endangered species, after an agreement was reached between the agency and the Natural Resources Defense Council (NRDC). Imidacloprid is one of the most commonly used insecticides in the world today and, like other neonicotinoids in its chemical class, has been linked to a range of adverse impacts on wildlife and their habitat. While the agreement to the assess effects on endangered species is important, advocates note that EPA should already have conducted this review, and further, that imidacloprid and other neonicotinoids should already be banned. NRDC’s successful lawsuit follows a separate legal challenge by the Center for Food Safety, Beyond Pesticides, beekeepers, and other environmental organizations which was settled in 2019. The judge in that case, focused on the neonicotinoids clothianidin and thiamethoxam, did not order EPA to consult with the U.S. Fish and Wildlife Service (FWS) and National Marine Fisheries Service (NMFS) (which is required when registering a pesticide in order to mitigate risks to endangered species). Instead, she directed the parties, including the plaintiffs, defendant EPA, and intervenor Bayer CropScience (the manufacturer of neonicotinoids), to move forward […]

(Beyond Pesticides, January 13, 2021) An ethanol processing plant located in the small village of Mead, Nebraska has been using seeds coated in bee-toxic chemicals as part of its production process, according to reporting published in The Guardian earlier this week. The plant, owned by a company called AltEn, may be the only plant in the U.S. producing biofuels with toxic seeds. There is a reason for that, and Mead residents are experiencing the adverse effects of EPA not regulating treated seeds. The prevalence of the use of seed coatings in chemical agriculture has increased over the last several decades, as the pesticide industry works to increase product sales by exploiting a loophole in federal pesticide law. Under FIFRA (the Federal Insecticide Fungicide and Rodenticide Act), a clause known as the “treated article exemption” permits seeds to be coated with highly toxic pesticides without any requirement for the U.S. Environmental Protection Agency (EPA) to assess environmental or public health effects of their use. This allows hazardous pesticides (primarily insecticides and fungicides) to be used indiscriminately with no effective oversight. Research finds that over 150 million acres of farmland are planted with toxic seeds, including nearly four tons of bee-killing neonicotinoids […]

(Beyond Pesticides, November 11, 2020) Neonicotinoid insecticides inhibit honey bee sleep cycles, leading to stress and population declines, according to research from Vanderbilt University, published in Scientific Reports. Although there is already ample evidence of the dangers these systemic insecticides pose to pollinators – as evidenced by recent bans in the European Union and Canada – this new line of investigation add further detail to the ongoing crisis in the pollinator world. “I was thinking about honey bee disappearances and it clicked—if pesticides are killing bees indirectly but we don’t know exactly how, maybe it’s because they’re getting physically lost,” said study coauthor Michael Tackenberg, PhD.  Scientists conducted the experiment using honey bees located on Vanderbilt’s campus, which does not use neonicotinoid insecticides. After returning from pollen collection, forager bees were captured at their hive entrance and moved into monitoring tubes, which were subsequently transferred to the lab. In the lab, scientists were able to control light and dark cycles, and exposed bees to levels neonicotinoids they would likely experience if foraging on contaminated flowers. Foraging bees were first exposed to light/dark at 12/12 cycles, followed by four days of complete darkness, at which time some bees were provided neonics, […]

(Beyond Pesticides, October 20, 2020) The additive stress of pesticide exposure and food scarcity leads to significant declines in wild pollinator populations, according to research published by scientists at University of California, Davis. Although it is well known that insect and pollinators populations are at risk from multiple stressors related to industrial agriculture, comprehensive evaluations are a challenging scientific undertaking. “Just like humans, bees don’t face one single stress or threat,” said lead author Clara Stuligross, a PhD. candidate in ecology at UC Davis. “Understanding how multiple stressors interplay is really important, especially for bee populations in agricultural systems, where wild bees are commonly exposed to pesticides and food can be scarce.” To better understand the interplay between these two stressors, researchers designed a field study. Mason bee pollinators were provided cages to nest in, and each stressor was separated out. One set of bees were provided high levels of food availability, while another received scant floral resources. Certain cages within each food level were treated with the product Admire Pro, a Bayer Cropscience insecticide containing the neonicotinoid imidacloprid. Scientists found significant impacts on the factors that deal with mason bees’ reproductive success. This includes the likelihood that a female […]

(Beyond Pesticides, October 7, 2020) This week the Baltimore, Maryland City Council passed an ordinance restricting the use of toxic pesticides on public and private property—including lawns, playing fields, playgrounds, children’s facility (except school system property [golf courses are exempt]—following an approach similar to legislation first spearheaded by Montgomery County, MD in 2015. While the legislation, 20-0495, An Ordinance Concerning Pesticide Control and Regulation, generally limits inputs to the allowed materials under federal organic law, it provides for allowances for glyphosate by the Department of  Recreation and Parks. If signed by the Mayor, as expected, Baltimore City will become the most recent Maryland jurisdiction to exercise its authority to regulate pesticide use on private property, after a ruling of the state’s highest court. Language in the Baltimore ordinance tracks a similar framework to the Healthy Lawns Act passed in Montgomery County, Maryland. Any pesticide that is not compatible with organic land care—allowed under certified organic by the U.S. Department of Agriculture (USDA) or considered minimum risk by the U.S. Environmental Protection Agency (EPA)—is subject to the bill’s restrictions. Use can only occur under limited exceptions, such as to manage particularly invasive species, as well as health or economic threats. Bee-toxic […]

(Beyond Pesticides, September 30, 2020) Low doses of neonicotinoid (neonic) insecticides are known to disrupt insect learning and behavior, but new science is providing a better understanding of how these effects manifest at a cellular level. Published in the Proceedings of the National Academy of Sciences, this study finds that the neonic imidacloprid binds to brain receptors, triggering oxidative stress, reducing energy levels, and causing neurodegeneration. “Although many studies have shown that low doses of insecticides can affect insect behavior, they have not uncovered whether insecticides trigger changes at the cellular and molecular levels,” said lead author Felipe Martelli, PhD, of Monash University in Melbourne, Australia. “The goal of this work was to have a better understanding of the effects of low doses of the common insecticide imidacloprid at the cellular, physiological and behavioral levels.” Researchers used the fruit fly Drosophilia melanogaster, a common experimental organism, as it contains a number of nicotinic acetylchloline receptors, the primary site of action for imidaclorpid. The neonic binds to these receptors, which regulate a number of physiological processes, such muscle contraction. Binding closes these channels, leading to the range of harm researchers observed through their study. Larval fuit flies were exposed to imidacloprid […]

(Beyond Pesticides, August 26, 2020) Neonicotinoid insecticides damage the health of shrimp and oysters, according to two (1, 2) new studies published by Australian researchers. Although this class of chemicals is best known for its hazardous impacts on pollinator populations, it is becoming increasingly clear that the entire food chain is at risk from continued neonicotinoid use. This study builds on an already established body of literature showing these systemic chemicals poison waterways. Researchers began by collecting samples of shrimp and oysters from growers along the coast, and acclimating the species to laboratory conditions. Both collections were separated into different test groups. Oysters where exposed in their tanks to various concentrations of the neonicotinoid imidacloprid. Shrimp were exposed to imidacloprid through two methods: in their feed, and in their tanks. Each separate test group was further separated into high and low exposures. A control group that did not receive any pesticide exposure was also established in each experiment. For the oyster populations, scientists found a range of negative effects. Imidacloprid inhibits the proper functioning of the enzyme acetylcholinesterase, a well-known impact of many pesticides that results in damage to the nervous system. Detoxification mechanisms are activated, and changes are observed […]