29
Jul
(Beyond Pesticides, July 29, 2019) A research study, published in March in Scientific Reports, uncovers a pesticide effect on a sugar-metabolizing enzyme common to all cells that has broad health ramifications ignored by the U.S. Environmental Protection Agency’s (EPA) safety testing protocol. This finding raises a larger question regarding the need for EPA to test for the synergistic effects of pesticides, whereby pesticides and chemicals in combination have an even greater effect than they do by themselves. The research, by T. Tristan Brandhorst, PhD, Iain Kean, PhD, and others in the lab of Bruce Klein, PhD, of the University of Wisconsin–Madison and UW School ofMedicine and Public Health, specifically sheds light on the mode of action of the fungicide fludioxonil. Fludioxonil, a phenylpyrrole fungicide, was developed to treat seeds during storage, and has come to be used commonly on grains, vegetables, fruits, and ornamental plants during cultivation, and produce after harvest to extend “shelf life.” As reported by the American Association for the Advancement of Science publication, EurekAlert, “The ability of [the fungicide] fludioxonil to act on a sugar-metabolizing enzyme common to all cells, and to produce the damaging compound methylglyoxal, may mean that the pesticide has more potential to harm non-fungal cells than previously […]
Posted in Agriculture, Environmental Protection Agency (EPA), fludioxonil, Fungicides, Oxidative Stress, Pesticide Regulation, synergistic effects, Take Action, Uncategorized | 1 Comment »
05
Jul
(Beyond Pesticides, July 5, 2019) This is a story about a chemical pesticide, a fungicide, in wide use for which the mode of action, i.e., the ability to cause harm, has not been fully understood. It is not a story unique to this pesticide. Rather, it is an important story to consider when deciding to use a pesticide or allowing a pesticide to be used. The question is whether the chemical could be broadly problematic beyond the target organisms, in this case fungi? In its coverage of a study published in March, the American Association for the Advancement of Science publication, EurekAlert, reported that, “The ability of [the fungicide] fludioxonil to act on a sugar-metabolizing enzyme common to all cells, and to produce the damaging compound methylglyoxal, may mean that the pesticide has more potential to harm non-fungal cells than previously thought. Although fludioxonil has been deemed safe for use, the authors . . . suggest that the effects of this widely used pesticide has upon animals be re-examined.” The research study, published in March in Scientific Reports and led by T. Tristan Brandhorst, PhD (in the lab of Dr. Bruce Klein at the University of Wisconsin–Madison and UW School of […]
Posted in Environmental Protection Agency (EPA), fludioxonil, Fungicides, Syngenta, Uncategorized | No Comments »
25
Apr
(Beyond Pesticides, April 25, 2019) As reported by Mother Jones, the New York Times (NYT) published, on April 6, a distressing report about a deadly fungus that has been advancing steadily across the world during the past five years. Candida auris is an emerging fungal pathogen that threatens those with compromised or immature immune systems, such as infants, the elderly, people taking steroids for autoimmune disorders, diabetics, those undergoing chemotherapy, and even smokers. Nearly half of those who contract a C. auris infection die within 90 days. One of the factors making this fungus so deadly is that it has developed resistance to existing antifungal medicines, with 90% of infections resistant to one drug, and 30% to two or more. As is true for resistant bacteria, culprits in C. auris’s development of resistance may be the overuse of antifungal medications in health care and overreliance on fungicides in agriculture. The Centers for Disease Control and Prevention (CDC) has added C. auris to its list of pathogens considered “urgent threats.” It is an “emerging fungal pathogen,” meaning that the incidence of infection has been increasing across multiple countries since it was first recognized in 2009 in Japan (although a different strain had […]
Posted in Agriculture, Antibiotic Resistance, Centers for Disease Control and Prevention, Fungicides, Resistance, Uncategorized | No Comments »
30
Nov
(Beyond Pesticides, November 30, 2018) A study published this month in Science of the Total Environment reveals numerous pesticide residues persisting in soil, harming the viability of agricultural lands and increasing risk of off-site contamination. Funded by the Horizon 2020 programme of the European Commission, researchers from the European Diverfarming project at the University of Wageningen in the Netherlands suggest nations urgently reevaluate conventional land use and inputs including water, energy, fertilizers, machinery and pesticides. Researchers decrying the lack of soil protection policies endeavored to determine which pesticides had the highest soil persistence and toxicity to non-target species. Three hundred seventeen surface soil samples were analyzed from 11 European countries. Selected countries were those with the largest amounts of active agricultural land, characterizing six distinct cropping systems. Sampled soils purposefully represented different soil properties and were taken from crops with the highest pesticide use per hectare. Samples were then analyzed for the concentration of 76 pesticide residues. These 76 pesticides were selected as being most often applied on conventional crops. Eighty-three percent of samples contained varying degrees of pesticide residues, with 25 percent showing one pesticide residue and 58 percent showing mixtures of two or more. Only 17 percent of […]
Posted in Biodiversity, Contamination, contamination, DDT, Disease/Health Effects, Fungicides, Genetic Engineering, Glyphosate, International, Persistence, Pesticide Residues, tebuconazole, Uncategorized | No Comments »
05
Dec
(Beyond Pesticides, December 5, 2017) Fungicides are likely playing an important role in the decline of North American bumblebee populations, according to new research published by a team at Cornell University. While overwhelming data continue to indicate that insecticides, particularly the neonicotinoid class of chemicals, are the leading factor in overall pollinator declines, Cornell scientists discovered that fungicides, in particular the chemical chlorothalonil, are likely compounding risk and toxicity for U.S. bumblebee species. As new studies continue to expand the chemical culprits in pollinator declines, calls for a wholesale change in agricultural practices toward more sustainable organic production are reinforced. Cornell researchers began their investigation by focusing on what land use factors had the most impact on eight bumblebee species, many of which have been declining in the U.S. Bumblebee species were sampled at nearly 300 sites in 40 states during the summer months, and at each of the sampling sites, landscape variables were characterized and quantified for land use (urban v rural), habitat (high vs low latitude), and pesticide (insecticide, fungicide, herbicide) usage. The strongest indicator of declining range within the selected bumblebee species was found to be overall fungicide use, with those in the northern U.S. undergoing the […]
Posted in Fungicides, Pollinators, Uncategorized | No Comments »
