(Beyond Pesticides, February 25, 2021) A University of Michigan study finds a link between elevated rates of breast cancer incidents and chemical exposure from pesticides among African American women. Breast cancer is the most common cancer among women, causing the second most cancer-related deaths in the United States. However, breast cancer outcomes differ significantly among women of various races/ethnicities, with African American women being 40 percent more likely to die from breast cancer than women of any other race. Furthermore, incidences of triple-negative breast cancer (TNBC)—an aggressive breast cancer subtype lacking remediation—is approximately three-fold higher in non-Hispanic Black women (NHBW) compared to non-Hispanic White women (NHWW). Although past studies suggest genetic and environmental factors interact to produce these differences in breast cancer outcomes, genetic factors only play a minor role while disparities (differences) in external factors (i.e., chemical exposure) may play a more notable role. This study highlights the significance of understanding how chemical exposure drives disease outcomes and increases disease risk, especially for more virulent diseases that disproportionately (unequally) impact specific communities. Prior research infers differences in chemical exposure may explain racial disparities for several illnesses, and growing evidence suggests common chemical exposure patterns influence the risk of breast cancer. […]

(Beyond Pesticides, December 7, 2020) The Trump Environmental Protection Agency (EPA) reversed in four years much of the progress made by EPA in decades, and that push continues. The Biden EPA needs to advance a new vision. Tell President-elect Biden to adopt a new direction for pesticide regulation. Challenge so-called “benefits” of pesticides. The Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) requires EPA to weigh risks against benefits when registering pesticides. Claimed “benefits” for toxic pesticides need to be judged in comparison to organic production, which is able to produce all types of food and feed. The Organic Trade Association reports that organic sales now exceed $55 billion per year, and the U.S. Department of Agriculture (USDA) finds that organic producers in the U.S. produced $9.9 billion worth of organic food on 5.5 million acres in 2019. EPA assumes benefits of pesticides, rather than measuring them, and does not take into account the development of resistance. The cost-competitive success of organic food production and nonagricultural land management practices make the case that toxic pesticides lack benefits. Protect pollinators. Agriculture relies on insect pollinators to facilitate fertilization and maintain annual crop yield. Globally, the production of crops dependent on pollinators is worth […]

(Beyond Pesticides, October 19, 2020) The COVID-19 epidemic has made clear to the general public what we at Beyond Pesticides have been stressing since our inception—some populations have disproportionate risk of severe outcomes, exposures to toxic chemicals can affect susceptibility to disease, comorbidity increases risk, and bad government can kill you. As Trump declares that “unborn children have never had a stronger defender in the White House,” we are reminded of Erik Jansson, who ran the National Network to Prevent Birth Defects and helped to convene the founding meeting of Beyond Pesticides, and took on then-Administrator of EPA Anne Gorsuch, calling her a “baby killer” because of policies that allowed exposures to toxic chemicals—exposures that endangered children and fetuses. Those were harsh words in the 1980s even when the Reagan administration’s environmental and toxics policies were tied to elevated harm to people, and children in particular. In today’s world, scientists and medical doctors are regularly linking elevated death rates from coronavirus to the federal government’s inadequate coronavirus policy and its attack on science. And, they are pointing to those in charge. Policies and decisions under the Trump administration that threaten the health of children and the unborn include: COVID-19 misinformation. […]

(Beyond Pesticides, September 18, 2020) In late August, Consumer Reports magazine (CR) issued a report titled, “Stop Eating Pesticides,” which offers consumers a rating system CR developed and employed to help them “get the health benefits from fruits and vegetables while minimizing [the] risk from toxic chemicals.” In addition to providing its analysis and ratings of the pesticide risk of a variety of produce items, CR recommends eating organically grown and raised foods whenever possible. It also makes a host of recommendations on federal pesticide policies and emphasizes the importance of maintaining the integrity of the National Organic Standards (of the USDA-housed National Organic Program). Beyond Pesticides appreciates that this mainstream publication has arrived at many shared, science-based assessments of the risks of pesticides. That said, a wholesale transition to organic and regenerative agriculture — rather than making the public figure out which fruits and vegetables are “safer” or “less safe” — is the real answer to the health risks of pesticides in the food supply, according to Beyond Pesticides. The CR analysis used data from the U.S. Department of Agriculture’s (USDA’s) Pesticide Data Program for 2014–2018. Those pesticide residue data were compiled from tests of approximately 450 pesticides across 24,000 […]

(Beyond Pesticides, August 11, 2020) Petitioners who mounted a legal challenge to the Environmental Protection Agency’s (EPA’s) registration of Enlist Duo, a relatively new and highly toxic pesticide product, recently learned of a mixed decision from the U.S. Ninth Circuit Court of Appeals in the case. The good news is that Judge Ryan D. Nelson, writing the opinion for the court, found that EPA, in registering the herbicide Enlist Duo, had failed to protect monarch butterflies, which are under consideration as a threatened species under the Endangered Species Act (ESA). On the other and disturbing hand, the court concluded that EPA registration of the product was otherwise lawful — which means that this toxic compound will for now remain on the market. As one of the plaintiffs in the case, Beyond Pesticides is adamant that this product should not be registered for use by EPA. George Kimbrell, Legal Director of Center for Food Safety and Lead Counsel for the plaintiffs, commented on the decision in the organization’s July 22 press release on the decision: “The panel majority’s unprecedented decision is contrary to controlling law and established science, and Center for Food Safety is analyzing all legal options, including seeking a full […]

(Beyond Pesticides, February 13, 2020) Congress unanimously passed the Food Quality Protection Act (FQPA) in 1996 to increase protections for children from pesticide exposure. Unfortunately, according to a new study published in Environmental Health, the law is not being employed by the Environmental Protection Agency (EPA) to its full capacity. For most of the 59 pesticides reviewed by the study, EPA did not apply an additional FQPA safety factor and thereby missed an opportunity to protect children’s health. In fact, FQPA solidified EPA’s reliance on risk assessment calculations and mitigation measures that consistently fall short of adequate levels of protection because of serious data gaps, a failure to consider exposure to mixtures and synergistic effects, and a bias against consideration of alternatives (alternatives assessment)  that show toxic pesticides to be unnecessary.  FQPA establishes a safety standard applied to all food commodities that considers specific risks for infants and children. The law requires EPA to assess the “aggregate risk” (considering exposure from multiple sources) and “cumulative exposure” to pesticides that have a “common mechanism of toxicity.” FQPA mandates “an additional tenfold margin of safety for the pesticide chemical residue and other sources of exposure shall be applied for infants and children […]

(Beyond Pesticides, January 15, 2019) A study published in the journal Environment International, Association of urinary metabolites of organophosphate and pyrethroid insecticides, and phenoxy herbicides with endometriosis, is the first of its kind. Researchers considered the endocrine-disrupting properties of pesticides (such as reduced sperm counts) and investigated whether there might be a relationship between pesticide exposure and endometriosis. Endometriosis is an estrogen-dependent gynecologic disease that affects about 176 million women globally. It can cause extreme pain and infertility as well as increased risk for cancer and cardiovascular diseases. This study finds a positive correlation between some pesticide metabolites and endometriosis, though authors encourage further study to corroborate the findings. Researchers examined exposure to 11 “universal pesticides” and their metabolites and its relationship to endometriosis in 492 reproductive-age women recruited from 14 surgical centers in Utah and California from 2007-2009. The women at these clinics were scheduled for laparoscopy or laparotomy—the “gold standard” for identifying endometriosis is through these surgeries. The study compares results from the clinical cohort to a group of women in the same age bracket from areas surrounding the participating clinics. 619 urine samples were analyzed from the operative and population cohorts. This study detected six of the […]

(Beyond Pesticides, January 10, 2020) A new study by researchers out of the University of Iowa College of Public Health, published in JAMA (the Journal of the American Medical Association) Internal Medicine, demonstrates that greater exposure to pyrethroid insecticides is associated with higher risks of death from all causes and from cardiovascular disease. These compounds can be inhaled, ingested, or absorbed through the skin; they are highly neurotoxic, and have also been linked to certain cancers, endocrine disruption, and suppression of the immune system, as well as respiratory and reproductive impacts. The researchers gathered data, for 2,116 adults aged 20 or older, from the National Health and Nutrition Examination Survey. Each of those subjects had contributed a urine sample at some point between 1999 and 2002. Urine samples reflect levels of a pyrethroid metabolite (3-phenoxybenzoic acid) present, which in turn offer information about pyrethroid exposure. The researchers followed the participants until 2015; the research analysis was performed in the summer of 2019. Data were adjusted to accommodate multiple factors (age, sex, ethnicity, socioeconomic status, diet and lifestyle, smoking status, body mass index, and urinary creatinine levels). The co-authors report that subjects with the highest levels of metabolites had a 56% […]

(Beyond Pesticides, November 25, 2019) Continuing its marathon of deregulation to benefit the chemical industry, the Trump administration’s Environmental Protection Agency (EPA) announced its proposal to increase the amount of the weed killer atrazine allowed in U.S. waterways by 50% during the chemical’s registration review—a stark reversal of previous proposals to significantly reduce atrazine levels in the environment. The atrazine proposal follows closely on the heels of a proposal to further weaken protections regarding 23 pyrethroid insecticides that have been repeatedly linked by peer-reviewed studies to neurological issues such as learning disabilities in children. Ask Congress to request an investigation into whether EPA is ignoring its statutory duty and regulatory requirements to use science in its proposals. EPA’s atrazine proposal comes after agrichemical giant Syngenta and the National Corn Growers Association requested that EPA dismiss independent research regarding the adverse impact of atrazine. Atrazine, a broadleaf herbicide, is linked to endocrine disruption, neuropathy, and cancer. It disrupts the sexual development of frogs at levels far below the current allowed concentrations by EPA. Studies by Tyrone Hayes, PhD, University of California, Berkeley, and others have shown that concentrations as low as 0.1 ppb turn tadpoles into hermaphrodites. A 2009 study linked birth defects like gastroschisis and choanal atresia to the relative concentrations of atrazine and other pesticides […]

(Beyond Pesticides, November 14, 2019) The Environmental Protection Agency (EPA), under pressure from chemical companies, released a proposal on Tuesday to further weaken protections regarding 23 pyrethroids. Pyrethroids are a common class of neurotoxic insecticides that have been repeatedly linked by peer-reviewed studies to neurological issues such as learning disabilities in children. They are also extremely damaging to non-target invertebrates, according to EPA’s own analysis. Despite this, EPA had already recently undermined protections for children from these chemicals, and the Trump Administration is now embracing industry proposals to further remove other safety barriers to human health and the environment. The Pyrethroid Working Group, a weighty working group of pesticide companies, requested EPA reduce safeguards such as a permanent 66-foot vegetation buffer between fields and water bodies to a 10 – 25-foot buffer. Also, the working group (and now EPA) suggests that the wind-speed cutoff for spraying should be increased from 10 mph to 15 mph. EPA’s announcement proposes the reapproval of five out the 23 pyrethroids; proposals regarding the rest are already pending approval. EPA is accepting public comments on the proposal until January 13, 2020. As mentioned, this is only the latest detrimental decision EPA has put forth regarding […]

(Beyond Pesticides, August 12, 2019) Once again, the Environmental Protection Agency (EPA) has rejected the evidence provided by independent scientists and sided with the pesticide industry promoting its products; this time, removing a safety for factor for children on some of the most widely used insecticides, synthetic pyrethroids. When EPA cannot do its job, it is time for Congress to step in. Tell Congress: To Protect Children, EPA Must Consider the Independent Peer-Reviewed Science, Not Bend to Industry Lobbying. In a move that challenges the preponderance of independent peer-reviewed scientific findings on children’s health, EPA recently stripped away protections that limit children’s exposure to class of chemicals associated with childhood cancer, autism other learning disorders, and asthma. The result of the agency’s actions will be a dramatic increase in the use of synthetic pyrethroids, insecticides found in indoor and outdoor bug sprays, bug bombs, and often used on conventionally grown fruits and vegetables. EPA, under the leadership of former fossil fuel lobbyist Andrew Wheeler, is embracing the positions of the pesticide industry while ignoring independent science and health and environmental groups. In 2017, the agrichemical industry trade group, Croplife America, submitted comments to EPA during its review of synthetic pyrethroids. The organization urged EPA to rely on a […]

(Beyond Pesticides, August 6, 2019) In a move that challenges the preponderance of independent peer-reviewed scientific findings on children’s health, the U.S. Environmental Protection Agency (EPA) recently stripped away protections that limit children’s exposure to a class of chemicals associated with childhood cancer, autism, and other learning disorders. The result of the agency’s actions will dramatically increase the use of synthetic pyrethroids, insecticides found in indoor and outdoor bug sprays, bug bombs, and often used on conventionally grown fruits and vegetables. EPA, under the leadership of former fossil fuel lobbyist Andrew Wheeler, is embracing the positions of the pesticide industry while ignoring independent science and health and environmental groups. In 2017, the agrichemical industry trade group, Croplife America, submitted comments to EPA during its review of synthetic pyrethroids. The organization urged EPA to rely on a health model developed by a different industry group, known as the Council for the Advancement of Pyrethroid Human Risk Assessment (CAPHRA), in determining the “safety factor” to apply to children. “Safety factors” for children are required under a 1996 law, the Food Quality Protection Act (FQPA), unless there is compelling evidence indicating the additional margin of safety is unnecessary. These factors generally require manufacturers to […]

(Beyond Pesticides, July 5, 2019) This is a story about a chemical pesticide, a fungicide, in wide use for which the mode of action, i.e., the ability to cause harm, has not been fully understood. It is not a story unique to this pesticide. Rather, it is an important story to consider when deciding to use a pesticide or allowing a pesticide to be used. The question is whether the chemical could be broadly problematic beyond the target organisms, in this case fungi? In its coverage of a study published in March, the American Association for the Advancement of Science publication, EurekAlert, reported that, “The ability of [the fungicide] fludioxonil to act on a sugar-metabolizing enzyme common to all cells, and to produce the damaging compound methylglyoxal, may mean that the pesticide has more potential to harm non-fungal cells than previously thought. Although fludioxonil has been deemed safe for use, the authors . . . suggest that the effects of this widely used pesticide has upon animals be re-examined.” The research study, published in March in Scientific Reports and led by T. Tristan Brandhorst, PhD (in the lab of Dr. Bruce Klein at the University of Wisconsin–Madison and UW School of […]

(Beyond Pesticides, July 1, 2019) France made a decision in May to ban a widely-used fungicide because it damages the endocrine system. In contrast, there has been a stark failure to protect health in the U.S. Despite a Congressional mandate, EPA is not acting on endocrine disruptors linked to infertility and other reproductive disorders, diabetes, cardiovascular disease, obesity, and early puberty, as well as attention deficit hyperactivity disorder (ADHD), Parkinson’s, Alzheimer’s, and childhood and adult cancers. This is a tragedy. Ask your elected members of Congress to demand that EPA tests and acts on regulatory endocrine disruptors as required by law. In 1998, following a mandate in the Food Quality Protection Act (FQPA) of 1996, EPA established a program to screen and test pesticides and other widespread chemical substances for endocrine disrupting effects. Despite operating for 21 years, the Endocrine Disruptor Screening Program (EDSP) has made little progress in reviewing and regulating endocrine-disrupting pesticides.  As of 2019, the program has stalled entirely. To ensure appropriate follow-through, Congress gave EPA a timeline to: develop a peer-reviewed screening and testing plan with public input not later than two years after enactment (August 1998); implement screening and testing not later than three years after […]

(Beyond Pesticides, May 2, 2019) Researchers have documented an increase in food and drinking water residues of neonicotinoids, insecticides linked to breast cancer. Using the Pesticide Data Program (PDP), 1999-2015, of the U.S. Department of Agriculture, the researchers identified near-peak detection frequencies in 2015, after a decline from 2008-2013. Imidacloprid remains the most common neonicotinoid detected across imported commodities, while the neonicotinoids clothianidin, thiamethoxam, acetamiprid, and flonicamid are replacing imidacloprid in domestic production. Authors note that these newer neonicotinoids are potentially more toxic than imidacloprid, raising concerns for understudied human health and environmental impacts. The study, Trends in neonicotinoid pesticide residues in food and water in the United States, 1999–2015, published in the journal Environmental Health, finds the highest detection frequencies for neonicotinoids in drinking water, with 30% of treated drinking water turning out positive for imidacloprid in 2011. Certain fruits and vegetables are also frequently contaminated by neonicotinoids, with detection frequencies ranging from 20% to as high as 57% in the case of imidacloprid on cauliflower. While the study points to specific fruits and vegetables as posing higher risk, the main message reaches beyond individual commodity or individual neonicotinoid results. Authors uncover a systematic increase in detection of neonicotinoid […]

(Beyond Pesticides, March 29, 2019) The U.S. Environmental Protection Agency (EPA) made a low-key announcement on March 19 suggesting that it may change its handling of requests from states to exert stricter controls on use of pesticides than the federal agency sets out in its registration of the compounds — by disapproving them. This is potentially a big deal because it signals that the agency will be less-kindly disposed to states’ desires to establish either somewhat different parameters of use based on local conditions and needs, or more-stringent regulations on pesticide use than those set out by federal regulators. This issue of preemption of localities’ desires to protect their populations and environment has become an increasingly dynamic frontier at the nexus of pesticide use, health, and environment. Beyond Pesticides has written more frequently about this issue in recent years as the tension between centralized, federal regulation and more-local regulation has risen; see more below. EPA appears distressed by some of the approximately 300 annual requests it gets to make some adjustment to the federal regulation. This can happen under Section 24(c) of FIFRA, which allows for a Special Local Need Label, which can be requested under a variety of conditions, including […]

(Beyond Pesticides, January 14, 2019)  A petition submitted on January 7 by the Center for Biological Diversity calls on the National Marine Fisheries Service (NMFS) and the U.S. Fish and Wildlife Service (FWS) to initiate rulemaking to proscribe nearly all pesticide use in areas that are deemed critical habitat for endangered species. It asks these federal agencies to use the authority they have under the 1973 Endangered Species Act (ESA) to protect wildlife from the threats represented by pesticides — which threats both agencies have long recognized. The language of the ESA says its purpose is “to provide a means whereby the ecosystems upon which endangered species and threatened species depend may be conserved.” In its press release on the petition, the Center for Biological Diversity (CBD) notes that it comes “after decades of intransigence by the Environmental Protection Agency, which has refused to comply with the legal mandates of the Endangered Species Act to protect the nation’s most imperiled species from highly toxic pesticides like chlorpyrifos and atrazine that are known to harm wildlife.” CBD environmental health director Lori Ann Burd said, “Pesticides pose a devastating danger to endangered wildlife, from coast to coast. If the EPA isn’t going to […]

(Beyond Pesticides, March 2, 2017) On Tuesday, the European Commission (EC) refrained from voting on proposed scientific criteria that would have identified endocrine disrupting chemicals (EDC) and led to regulation on their use in EU countries. This sends the Commission back to the drawing board on the proposal, on which they hope to eventually take a formal vote. The failure to move forward with defined criteria on these hazardous chemicals, which are present in pesticides, biocides, and self-care products, is still largely due to the disagreements of voting member states over the rules reflecting hazard or risk-based criteria. There have been several other meetings of the member states on this proposal, including a meeting in December which highlighted the inadequacies of the criteria. After this meeting, according to Bas Eickhout, of the Greens-European Free Alliance, “Under the Commission’s criteria, it is likely that not a single substance would be identified as an endocrine disrupter, and they would effectively escape specific regulation.” This all follows on the weak regulations issued by the EC in June 2016 to regulate endocrine disruptors in pesticide products, which ultimately undermine the precautionary legal standard that governs pesticide usage in Europe. Many scientists and advocacy organizations criticized […]

(Beyond Pesticides, January 9, 2017) After the U.S. Environmental Protection Agency (EPA) released its recent human health risk assessment for the organophosphate insecticide (OP) tetrachlorvinphos (TCVP) on December 21, 2016, the agency announced it was allowing the continued use of the neurotoxic chemical to which children are widely exposed through pets’ flea collars and other flea treatments. According to EPA, ” TCVP is used as a direct animal treatment to livestock (i.e., cattle, horses, poultry and swine) and their premises, in kennels, outdoors as a perimeter treatment, and as a flea treatment [including flea collars] on cats and dogs.” In its announcement on January 4, 2017, EPA states, “We advise consumers to take certain precautions when handling TCVP products in residential areas. These precautions are listed on TCVP product labels, including: not allowing children to play with TCVP pet collar products, keeping TCVP spray and powder products out of reach of children, and washing hands thoroughly with soap and water after handling.” Advocates have raised concerns related to similar decisions on flea collars in the past in which EPA has issued warnings to mitigate risks, despite its inability to ensure children’s safety. Children typically come into close contact with pets and their […]

(Beyond Pesticides, October 21, 2016) Last week, the U.S. Environmental Protection Agency (EPA) postponed  a long-planned Scientific Advisory Panel (SAP) on the carcinogenicity of the widely used herbicide glyphosate due to “recent changes in the availability of experts for the peer review panel.”  However, as veteran journalist, formerly with Reuters, Carey Gillam reports in the Huffington Post, the move was likely the result of a letter industry front group CropLife America sent to EPA just days before the postponement, challenging the bias of certain experts on the panel. Croplife America is a national trade association that represents manufacturers, formulators, and distributors of pesticides, and has a vested interest in tamping down consumer concerns over glyphosate’s carcinogenicity. CropLife’s letter focuses in on two experts that were set to present in front of the EPA panel, Peter Infante, Dr.PH., and Kenneth Portier, PhD. CropLife writes that Dr. Infante will “reflexively discount any and all industry sponsored studies”¦” and indicates that his bias should preclude him from participation in the SAP. The group also asserts that Dr. Portier, who despite admission that “he has not previously testified against or otherwise expressed the patent bias against pesticide manufacturers,” should not be completely disqualified from […]

(Beyond Pesticides, June 21, 2016) New regulations issued by the European Commission (EU) last week to regulate endocrine disruptors in pesticide products are being criticized by public interest groups and scientists as undermining the precautionary legal standard governing pesticide use in Europe. Previous  investigations and reports  have uncovered  industry’s attempt to quash efforts to enact robust protections from these harmful chemicals, despite their likely contribution to billions of dollars in lost revenue due to health effects. EC’s new rules endorse the World Health Organization’s definition of endocrine disrupting chemicals (EDC). The WHO defines an endocrine disruptor as “an exogenous substance or mixture that alters function(s) of the endocrine system and consequently causes adverse health effects in an intact organism, or its progeny, or (sub)populations,” However, the proposed regulations go little beyond defining the term. “The WHO definition is not a criteria, it is just a definition,” said Andreas Kortenkamp, PhD to The Guardian. “In effect, the commission has decided to place the burden of deciding how to regulate endocrine-disrupting chemicals onto the assessors on a case-by-case basis.” Of concern is the level to which the rules reflect a hazard or risk-based criteria. While EC asserts that its rules will follow […]

(Beyond Pesticides, June 14, 2016) A new report released yesterday by the Environmental Working Group (EWG) has found that up to 420 known or likely carcinogens have been measured in a diverse array of populations, and that exposure to these carcinogens is not limited to on-the-job contact with industrial chemicals, including pesticides. According to the National Cancer Institute, an estimated 1.7 million new cases will be diagnosed in the U.S. in 2016. While some of these cases may be due to genetic makeup, others may be caused by substances in the air, soil, food and other materials in our environment. Through a review of scientific literature and publicly available biomonitoring studies, EWG compiled a comprehensive inventory of known or likely carcinogens that have been measured in people. According to the EWG report, data from the National Health and Nutrition Survey, or NHANES, conducted annually by the Centers for Disease Control and Prevention, confirms that many of these carcinogens are in the bodies of Americans not at risk of occupational exposure — indeed, at any given time some people may harbor dozens or hundreds of cancer-causing chemicals. Over half of the people tested had levels of arsenic and acrylamide in their […]

(Beyond Pesticides, April 27, 2016) The  European Union (EU)  has placed a moratorium on two endocrine-disrupting herbicides that are linked to thyroid cancer, infertility, reproductive problems and fetal malformations. The chemicals, amitrole and isoproturon, will be banned as of September 30, 2016, after the European Commission voted unanimously, for the first time, to ban the two endocrine disruptors. Earlier this month, the European Commission’s Standing Committee on Phytopharmaceuticals voted to ban the uses of amitrole and isoproturon in accordance with 2009-EU pesticide rules,  which state that endocrine disrupting pesticides should not be allowed on the European market. The committee finds that amitrole is capable of causing malformations in offspring and inducing thyroid cancer, while isoproturon can cause adverse effects to reproduction and lower fertility. In 2013 amitrole was voluntarily cancelled by the registrant, while isoproturon is not registered for use in the U.S. According to the Guardian, amitrole is widely used in 10 EU countries, including the UK, in industrial farming. But  a European Food Safety Authority (EFSA) analysis concluded  that it was an endocrine disruptor that could damage unborn children, and have toxic effects on the thyroid and reproductive organs. Similarly, EFSA recommended classifying  isoproturon as toxic for reproduction […]