(Beyond Pesticides, April 24, 2013) Using the aquatic species Daphnia, commonly referred to as “water fleas,” scientists at North Carolina State University (NC State) determined that exposure to the pesticide pyriproxyfen impacted multiple generations, ultimately resulting in more male offspring, and causing reproductive problems in female offspring. Lead author Gerald LeBlanc, PhD, notes, “This work supports the hypothesis that exposure to some environmental chemicals during sensitive periods of development can cause significant health problems for those organisms later in life —and affect their offspring and, possibly, their offspring’s offspring.” The study, published in the journal PLoS One, provides the scientific community with new information on how organisms respond to the environmental signals resulting from pesticide exposure. Environmental cues normally determine whether the Daphina offspring will be male or female, according to the researchers. This study is part of an investigation to understand the mechanisms involved with these environmental cues. The NC State team had previously identified the hormone methyl farnesoate (Mf) as an important factor in determining the sex of the organisms at the embryotic stage. The scientists exposed Daphnia to varying levels of the pesticide pyriproxyfen, an insecticide that mimics the Mf hormone. The exposure resulted in Daphnia producing […]

(Beyond Pesticides, April, 23, 2013) A report released by the Surface Water Ambient Montioring Program (SWAP) has found in California that “detection of pyrethroid pesticides in sediment increased from 55 percent of the statewide samples in 2008 to 85 percent in 2010.” The findings are among the results of the Stream Pollution Treads, or SPoT, monitoring program, an annual assessment of pollution in streams in California. The report also found that stream beds in urban areas have higher levels of pyrethroids that those in agricultural areas. The SWAP report summarizes results of the 2009 and 2010 annual surveys and compares those results to the 2008 SPoT data. Beyond the 30 percent increase of pyerthriods detected in sediment, the percentage of highly toxic samples increased from 6 percent to 67 percent when toxicity tests were conducted at a colder temperature that more closely matched the normal surface water temperature in average watersheds. These results, according to the report, “suggest that current monitoring may underestimate the occurrence of parathyroid-associated toxicity using the standard protocol.”   The report also acknowledges that some pyrethroids, such as bifenthrin, may persist longer than others, and the chronic impacts of these pesticides may be underestimated by some […]

(Beyond Pesticides, April 3, 2013)   Last week, Syngenta and Bayer CropScience proposed an action plan to forestall pending European Union (EU) restrictions on their neonicotinoid products that have been linked to global bee declines.   Stating that a ban on their products would not save hives, the plan focuses on implementing agricultural best management practices, planting habitat, and new research and development, all of which fail to seriously address the real problem that their products are highly toxic to bees. This new industry plan comes on the heels of the European Union (EU) stalemate on bee health, and after the EU food safety agency concluded that certain neonicotinoids pose unacceptable risks to bees. Public and regulatory scrutiny is now focused on the class of chemicals — neonicotinoids— linked to bee health decline. Neonicotinoids have been shown by numerous studies to adversely impact the health of  bees, as well as  birds and aquatic organisms. Beyond Pesticides, Center for Food Safety, and Pesticide Action Network North America joined beekeepers and other environmental and public health advocacy groups to sue the U.S. Environmental Protection Agency (EPA), calling for the suspension of the neonicotinoids, clothianidin and thiamethoxam. The science continues to document these […]

(Beyond Pesticides, March 1, 2013) In a literature review published in Toxicology last week, researchers found that environmental and occupational pesticide exposure was strongly associated with declines in sperm count. Researchers Sheena Martenies, BS, and Melissa Perry, ScD., MHS., determined that of the 17 studies evaluated, 15 of them reported significant associations between pesticides and semen quality. The researchers counted semen quality according to concentration of sperm over an area, their motility and ability to move, as well as their shapes. Researchers targeted studies on DDT, HCH, and abamectin, grouping pyrethroids and organophosphates by class. What they found was striking: almost all the studies reported a decrease in sperm concentration; decreased motility was also reported though less frequently; while morphological changes were not strongly associated in studies””only two indicated any changes to sperm shape. These findings build on a growing body of evidence that pesticide exposure at environmental or occupational levels diminished sperm health. In addition to the U.S. findings,  studies conducted on French, New Zealander, Indian, Tunisian, and Israeli men have all found decline in sperm count. Some studies record a drop by approximately 50% between 1940 and 1990, no small amount. These results might not be surprising as […]

(Beyond Pesticides, February 20, 2013) A new report by the United Nations Environment Programme (UNEP) and the World Health Organization (WHO) has identified endocrine disrupting chemicals as having significant health implications for the global population. According to the report, these chemicals have the capacity to interfere with tissue and organ development and function, and therefore they may alter susceptibility to different types of diseases throughout life, and represents a global threat that needs to be resolved. The report cites insufficient reporting and information on chemicals in products, materials and goods and calls for more research and collaboration. The State of the Science of Endocrine Disrupting Chemicals,   a joint study by UNEP and WHO, finds that endocrine disrupting chemicals (EDCs) are important environmental risk factors for endocrine diseases. Exposures during critical phases of development play an important role in the onset of many diseases, affecting future generations. Trends indicate an increasing burden of certain endocrine diseases across the globe, and it is clear from human studies that populations are exposed to perhaps hundreds of environmental chemicals at any one time. This UN study, which is the most comprehensive report on EDCs to date, highlights some association between exposure to EDCs […]

(Beyond Pesticides, February 15, 2013) Bats around the U.S. are being decimated by White Nose Syndrome (WNS). The deadly disease was detected recently at Kentucky’s Cumberland Gap National Historic Park, according to the National Park Service. Based on laboratory testing, three bats were discovered with WNS, coming from three separate caves in the park. The cold-loving fungus thrives on hibernating bats, spreading in 2006 from a cave in New York State to 21 other states in the East and Midwest. In 19 of these states there have been confirmed cases of WNS, not including detections in four Canadian Provinces (see map).  White nose syndrome is usually transmitted bat-to-bat, although the spore can also spread through human clothing, shoes or gear. The fungus causing WNS, Geomyces destructan, is extremely lethal to hibernating bats–though posing no health threats to humans, pets, or other animals– killing 90% of bats where the fungus had persisted for a year or more, totaling 5.8 million bat deaths since 2006. There are six species of cave-dwelling bats that are susceptible to WNS, including the endangered Indiana bat. There are also three species of tree-dwelling bats in the parks, but these are less at risk for contamination as […]

(Beyond Pesticides, February 11, 2013) The U.S. Environmental Protection Agency (EPA) has announced its decision to allow residues of the cancer causing insecticide endosulfan on imported Chinese teas until July 31, 2016. Its decision to provide “additional time to transition to an alternative to endosulfan” raises serious concerns of further exposure to the toxic carcinogen for farmworkers and consumers. In May 2011, EPA proposed to revoke all tolerances for endosulfan, as, “It can pose unacceptable health risks to farmworkers and wildlife and can persist in the environment.” The agency proposed transition time that would allow growers time to adopt alternatives, with the last four uses ending on July 31, 2016. For tea, EPA proposed an immediate revocation, since there is little if any endosulfan used in tea production in the U.S. However, the Chamber of Commerce of the Zhejiang International Tea Industry filed a complaint indicating that it would need five years or less to find feasible alternatives to endosulfan. It also indicated that it was unable to provide comment on the tolerance revocation ruling as the EPA did not provide proper notice to the World Trade Organization. In acknowledging this oversight, EPA will allow endosulfan residues of 24 parts […]

(Beyond Pesticides, February 8, 2013) A recent study conducted at the University of Granada, Spain and published in the Journal Environmental Research proposes a link between exposure to persistent organic pollutants (POPs) in food, air, and water and prevalence of type 2 diabetes in adults, regardless of age, gender, and body mass index. The paper concludes that people with higher concentrations of DDE, the break down product of DDT, are four times more likely to develop type 2 diabetes compared to other participants in the study. Increased rates of type 2 diabetes are also associated with exposure to beta-hexachlorocyclohexane, a break down product of the toxic chemical lindane, which in still allowed for use in agriculture and certain formulations of products used to treat lice and scabies. The study was carried out by analyzing the concentrations of specific POPs in adipose, or fat, tissue of 386 adults undergoing non-cancer-related surgery in Spain. According to one of the authors of the study, Juan Pedro Arrebola, “Human adipose tissue acts as an energy reservoir and has an important metabolic function. However, adipose tissue can store potentially harmful substances, such as POPs.”    The study found that as concentrations of POPs grows in […]

(Beyond Pesticides, January 23, 2013) A new federal report finds toxic contamination remains widespread in the Chesapeake Bay, with severe impacts in some places, which health and environmental advocates say lends support to their push in Maryland for legislative action on pesticides and other hazardous chemicals. In spite of some cleanup, the health of the Bay has not significantly improved. The report, “Technical Report on Toxic Contaminants in the Chesapeake Bay and its Watershed: Extent and Severity of Occurrence and Potential Biological Effects” is based on a review of integrated water-quality assessment reports from the jurisdictions in the Bay watershed (Delaware, Maryland, New York, Pennsylvania, Virginia, West Virginia, and Washington, D.C.), Federal and State reports, and articles in scientific journals. It notes that nearly three-fourths of the Bay’s tidal waters are “fully or partially impaired” by toxic chemicals, with people warned to limit fish consumption from certain areas. Contamination is severe in a handful of “hot spots” around the Bay, including Baltimore’s harbor, largely a legacy of past industrial and shipping activity. Previous reports have called on federal, state and local government to accelerate research into what threats chemical contamination may pose to the Bay, and to step up efforts […]

(Beyond Pesticides, January 8, 2013) Neurologists at the University of California, Los Angeles (UCLA) have published their latest research linking pesticide exposure to Parkinson’s disease. Appearing in the online edition of PNAS, the UCLA scientists’ work details the series of events that can occur after individuals are exposed to the pesticide benomyl, which was phased out in 2001. Researchers believe their findings on the series of events the pesticide sets in motion could be applicable even to Parkinson’s patients who have not been exposed to benomyl. According to scientists, exposure to benomyl prevents the enzyme aldehyde dehydrogenase (ALDH) from keeping in check a naturally occurring toxin in the brain called 3,4-Dihydroxyphenylacetaldehyde (DOPAL). Without ALDH regulating DOPAL, the toxin accumulates, damages neurons, and increases an individual’s risk of developing Parkinson’s disease. Researchers postulate that this process may be occurring in people with Parkinson’s who were never exposed to pesticides. The findings of this research provide insight into possible treatments to slow the disease, such as developing new drugs to protect ALDH activity. Although the exact cause of Parkinson’s is still unknown, until this research scientists were focusing in on the protein a-synuclein as a pathway to the disease. The protein, present […]

(Beyond Pesticides, December 3, 2012) The Food and Drug Administration (FDA) has denied a 2010 petition filed by the National Resources Defense Council (NRDC) and Pesticide Action Network North America (PAN) to ban the insecticide lindane, which is harmful to human health and ineffective in controlling lice and scabies. Pressure had been mounting on FDA to halt the pharmaceutical use of lindane as, in addition to this petition, Congressman Edward J. Markey (D-Mass.), senior member of the Energy and Commerce Committee, asked FDA to stop the pharmaceutical use of lindane this past summer. Because of FDA’s decision, lindane is still an active ingredient in pharmaceutical insecticide products such as lice shampoos and lotions. Lindane was formerly used in agricultural insecticides until it was banned by the Environmental Protection Agency (EPA) for use on crops in 2006. FDA regulates pharmaceuticals that contain insecticides and pesticides, such as triclosan, that are in cosmetics. Over 160 countries including the United States have signed on to the Stockholm Convention on Persistent Organic Pollutants (POPs) in 2001 which aims to eliminate or restrict the production and use of persistent organic polluntants. Lindane along with nine other chemcials was added to this list on May 9th […]

(Beyond Pesticides, November 26, 2012) The U.S Environmental Protection Agency’s (EPA) risk assessment process does not account for cumulative dietary exposure to the multitude of pesticides on conventional foods. The agency typically analyzes the exposure risk associated with each pesticide on an individual basis, except for those determined to have a common mechanism of toxicity. In light of these gaps in America’s regulatory process, researchers at UC Davis and UCLA in Cancer and non-cancer health effects from food contaminant exposures for children and adults in California: a risk assessment conducted an analysis of the toxics children and adults are exposed to through a normal diet. Rainbow Vogt, Ph.D., lead author of the study published in the journal Environmental Health, explains, “We focused on children because early exposure can have long-term effects on disease outcomes.” Researchers preformed their risk assessment by estimating exposure to food contaminants based on self-reported food frequency data for eleven toxic compounds- acrylamide, arsenic, lead, mercury, chlorpyrifos, permethrin, endosulfan, dieldrin, chlordane, DDE, and dioxin. Data was drawn from the 2007 Study of the Use of Products and Exposure-Related Behavior, which examines behaviors that influence exposure to toxicants in the home environment. Normal consumption patterns were then measured […]

(Beyond Pesticides, November 14, 2012) For years, scientists have shown that pesticide exposures are linked to the onset of Parkinson’s disease. Now a new study by researchers at University of California, Los Angeles, (UCLA) finds that exposure to pesticides and suffering a head injury are associated with a three-fold increase in one’s chances of developing Parkinson’s disease. Parkinson’s disease is the second most common neurodegenerative disease, and occurs when nerve cells in the substantia nigra region of the brain are damaged or destroyed and can no longer produce dopamine, a nerve-signaling molecule that helps control muscle movement. People with Parkinson’s disease have a variety of symptoms, including loss of muscle control, trembling and lack of coordination. Over time, symptoms intensify. At least one million Americans have Parkinson’s and about 50,000 new cases are diagnosed each year. The study, “Traumatic brain injury, paraquat exposure, and their relationship to Parkinson disease,” published in the journal Neurology surveyed more than 1,000 adults ages 35 and older who lived in central California. Some 357 of the participants were diagnosed with Parkinson’s disease. Participants with the disease were nearly twice as likely as those without the disease to report having had a head injury in […]

(Beyond Pesticides, November 7, 2012) Pregnant beluga whales pass to their fetus a portion of the persistent organic pollutants, PCBs and flame retardants, they carry in their bodies, report researchers who measured the chemicals in the animals’ blubber. The study is one of the first to show whales, like people, can transfer and expose their developing offspring to persistent contaminants, whose long-term health effects continue to remain unclear. A study of Arctic beluga whales (Delphinapterus leucas) confirms that mothers can pass more than a tenth of their chemical burden of PBDE flame retardants and PCBs to their unborn calves. This study found that the mother whales transferred, on average, 11.4% (7.5”‰mg) and 11.1% (0.1”‰mg) of their polychlorinated biphenyl (PCB) and polybrominated diphenyl ether (PBDE) blubber burden to their near-term fetuses. Mammals transfer contaminants, usually persistent organic pollutants (POPs), during pregnancy to the developing fetus and during lactation when the baby is nursing. Lactation transfer has been well studied in marine mammals, but very little is known about the transfer of pollutants during pregnancy. POPs are resistant to environmental degradation through chemical, biological, and photolytic processes. Because of this, they have been observed to persist in the environment, to be capable […]

(Beyond Pesticides, August 2, 2012) Following the phase-out announcement two years ago, and after many years of pressure from environmental and international groups concerned about the chemical’s health effects, the U.S. Environmental Protection Agency (EPA) has finally begun the process of phasing out the use of the highly toxic endosulfan –an organochlorine insecticide in the same chemical family as DDT. The phase of endosulfan uses began on July 31, 2012 and will continue through July 31, 2016. In 2010, EPA negotiated a long phase-out agreement with endosulfan’s manufacturers that allows uses to continue through 2016, even though EPA concluded that endosulfan’s significant risks to agricultural workers and wildlife outweigh its limited benefits to growers and consumers, and that there are risks above the agency’s level of concern for aquatic and terrestrial wildlife, as well as birds and mammals that consume aquatic prey that have ingested endosulfan. This is an egregious example of how EPA uses phase out and existing stock provisions in negotiating with industry on removing known hazards from the market, placing economic interests over the protection of public health. In 2010, EPA decided that data presented in response to its 2002 reregistration eligibility decision (RED) demonstrated that risks […]

(Beyond Pesticides, August 1, 2012) New research is adding to the evidence that some pesticides and industrial chemicals may increase women’s risk of uterine and ovarian diseases, such as endometriosis. The research supports the decades old theory that hormone-mimicking chemicals impact human reproductive systems. Scientists have long suspected a link between estrogen-mimicking pollutants and gynecological diseases. According to Environmental Health News, research investigating a link between hormone-disrupting chemicals in the environment and gynecological diseases has had mixed results. But a new study, “Persistent Lipophilic Environmental Chemicals and Endometriosis: The ENDO Study,” from researchers at the National Institutes of Health and others, found that two groups of women in the Salt Lake City and San Francisco areas — one group with pelvic pain and the other with no symptoms — were more likely to be diagnosed with endometriosis if they had high blood levels of the estrogen-like pesticide hexachlorocyclohexane (HCH) than women with low levels. HCH, a persistent organic pollutant (POP), and a byproduct of the production of the insecticide lindane (head lice treatments), has been banned as a crop pesticide in the United States but it persists in the environment and remains in some food supplies. Endometriosis is a female […]

(Beyond Pesticides, May 22, 2012) The Spanish-based Inesfly company announced recently its plans to release commercially pesticide encapsulated paint, Inesfly 5A IGR, containing two neurotoxic organophosphates (OPs), chlorpyrifos and diazinon, and the insect growth regulator (IGR), pyriproxyfen, which it hopes will combat malaria in sub-Saharan Africa. The company’s owner Pilar Mateo, PhD, calls her product “a vaccine for houses and buildings” and explains that because the insecticides are released slowly from the paint, it remains effective for two to four years. This formulation of Dr. Mateo’s paint could not be registered for use in the U.S. because both indoor residential uses of chlorpyrifos and diazinon have been banned because of risks posed to children’s health, although the company has another formulation that substitutes pyrethroids for the organophosphates. Though probably well-intentioned —Dr. Mateo has already invested $6 million of her family’s money and $12 million in grants from nonprofits, on research, creating educational programs about hygiene, and donating paint to more than 8,000 homes in Latin America and Africa””the product puts the people it is supposed to protect from disease at risk for other health problems. Organophosphate insecticides have been linked to a host of neurodevelopmental problems, especially in children. Because […]

(Beyond Pesticides, May 17, 2012) Rather than investing in safe, long-term solutions to prevent malaria mortality, the World Health Organization (WHO) has issued a strategic plan that calls for multiple toxic pesticides to combat mosquito resistance to insecticides that is showing up in sub-Saharan Africa. Insecticide resistance, according to the WHO report, is already rampant in 64 malaria-ridden countries and may result in as many as 26 million more cases of malaria a year, which could end up costing between $30 and $60 million annually for tests and medication. Mosquitoes in sub-Saharan African countries are becoming resistant to pyrethroid insecticides, which are used extensively for household spraying and treating bed nets, as well as to the organochloride compound DDT -which is still used in many parts of the world to control mosquitoes. In Somalia, Sudan and Turkey, resistance has spread to carbamates and organophosphates in addition to pyrethroids and organochloride pesticides. Rather than reducing the reliance on these products, WHO is recommending rotating classes of pesticides used to spray inside homes and developing a new non-pyrethroid insecticide to treat bed nets. Implementation for these suggestions are estimated to cost around $200 million, which is in addition to the $6 billion […]

(Beyond Pesticides, March 21, 2012) A half-century after California officials discovered that large amounts of the pesticide DDT had been discharged into a San Francisco Bay canal, the chemical is still poisoning fish and posing a threat to human health despite numerous cleanup attempts. After years of limited success with clean-up, the U.S. Environmental Protection Agency (EPA) has launched a three-year plan to pinpoint the cause of continuously high DDT levels and engage the surrounding community in cleanup and education efforts. The former plant and the adjacent canal, called the Lauritzen Channel, an inlet of the greater San Francisco bay, is one of the most polluted places in the nation. DDT levels have not decreased in the channel even after numerous dredging and other mitigation measures. In fact concentrations have increased. By 2011, DDT concentrations exceeded 1994 levels and some fish have DDT levels in their tissues hundreds of times higher than their counterparts in the rest of the San Francisco Bay. EPA said earlier this month it is launching a three-year plan to help unravel the mystery of why cleanup attempts are failing, and will work with the city to increase awareness among anglers who rely on bay fish […]

(Beyond Pesticides, March 6, 2012) New research conducted in New Bedford, Massachusetts suggests that organochlorine chemicals, which were first linked to learning problems in children more than two decades ago, may play a role in attention-deficit hyperactivity disorder (ADHD), especially in boys. Previous research has reported associations between organochlorines and ADHD-related behaviors, but this research found sex-specific effects in children born to mothers who lived near the contaminated harbor and dumpsites in low-income communities. This study adds to a growing body of literature associating learning disorders with prenatal chemical exposures. According to the study, Neuropsychological Measures of Attention and Impulse Control among 8-Year-Old Children Exposed Prenatally to Organochlorines, boys who were exposed to higher levels of the organochlorines -polychlorinated biphenyls (PCBs) and DDE (a metabolite of DDT)- in the womb scored lower on focus and concentration tests, which indicates they are more likely to have attention problems often related to ADHD. In the study, umbilical cord blood was collected from 788 newborns born between 1993 and 1998 from four towns near New Bedford Harbor, Mass., to see what they were exposed to in the womb. Roughly eight years after they were born, almost 600 of these children underwent two tests. […]

(Beyond Pesticides, February 22, 2012) Researchers have found high levels of endosulfan, a highly toxic organochlorine pesticide, in the bone marrow of children, including those suffering from hematological malignancies (blood cancers) in areas using the pesticide. Children who have endosulfan in their bone marrow have 7.5 times more risk of developing blood-related cancer compared to those with no detectable pesticide in the bone marrow. While the findings are based on research in India, the insecticide is still used in the production of dozens of crops in the U.S., even though EPA found that exposure to the chemical exceeds the agency’s acceptable risk criteria and announced in 2010 a six-year negotiated phase-out plan with industry that stretches from 2012 to 2016. Following a lawsuit filed against the U.S. Environmental Protection Agency (EPA) in 2008, which cited EPA’s glaring omission in not considering risks to children, EPA announced in 2010 that it would, instead of stopping exposure to a known hazard immediately, phase-out over a six year period all uses of endosulfan in the U.S. Rather than regulating a stop use, EPA astounded many in the environmental and public health community by negotiating a long phase-out agreement with manufacturers that allows some […]

(Beyond Pesticides, February 1, 2012) Pesticides could be suppressing vitamin D levels in people, leading to deficiency and disease, say scientists. This comes from a new study which discovered that adults with high serum concentrations of organochlorine pesticides, such as DDT, have lower vitamin D levels, further proving that these chemicals have a long-lasting impact on human health. While not widely appreciated, some organochlorine pesticides continue to be used in the U.S., resulting in exposure through our diet, environment, and prescription drugs, while most organochlorine pesticides have been banned in the U.S. and much of the world. Exposure to low doses of organochlorine pesticides has been previously linked to common diseases like type 2 diabetes, metabolic syndrome and cardiovascular disease. Vitamin D deficiency has similarly been associated with a rise in chronic diseases, but the two have been studied separately by researchers in different fields. The study, “Associations between Organochlorine Pesticides and Vitamin D Deficiency in the U.S. Population,” compared serum concentrations of organochlorine (OC) pesticides with serum concentrations of 25-hydroxyvitamin D (25(OH)D), a vitamin D pre-hormone, which is used to assess vitamin D levels in the body. It concludes that background exposure to some OC pesticides can lead to […]

(Beyond Pesticides, November 15, 2011) Research published in the online edition of Environmental Health Perspectives finds that exposure to certain pesticides elevates the risk of non-Hodgkin’s Lymphoma (NHL). The study, “A Prospective Study of Organochlorines in Adipose Tissue and Risk of non-Hodgkin’s Lymphoma,” finds a positive correlation between levels of the organochlorine pesticides DDT, cis-nonachlor, chlordane, and their breakdown products in human fat tissue and the often deadly form of cancer. The researchers from the Danish Cancer Society’s Institute of Cancer Epidemiology conducted a case-cohort study using a prospective Danish cohort of 57,053 persons enrolled between 1993 and 1997. Within the cohort they identified 256 persons diagnosed with NHL in the population-based nationwide Danish Cancer Registry and randomly selected 256 sub-cohort persons. The research team measured concentrations of eight pesticides and ten polychlorinated biphenyl congeners (PCBs) in fat tissue collected upon enrollment. The results indicate a higher risk of NHL in association with higher fat tissue levels of DDT, cis-nonachlor and oxychlordane, but shows no association with PCBs. Because the tissue samples were taken up to 15 years prior to the cancer diagnosis, the research suggests that exposure to these organochlorines increases the risk of NHL later in life and […]