(Beyond Pesticides, December 18, 2015) One of the most likely causes for the population decline of smallmouth bass in the Susquehanna River are endocrine-disrupting compounds and herbicides, concludes a multi-agency, multi-year study of one of the most complex river systems in Pennsylvania. The Pennsylvania Department of Environmental Protection (DEP) and the Pennsylvania Fish and Boat Commission (PFBC), along with nearly 50 participants and six partner agencies, released findings on Monday that narrow the likely causes from an initial field of 14 candidates to two. PFBC also found that pathogens and parasites are probable contributing factors. Following a smallmouth bass (SMB) population crash in 2005, and additional observed maladies, such as tumors and lesions on SMB, the team used ground-breaking monitoring strategies to collect more than 30,000 water quality records annually, along with review of existing research to isolate the possible causes keeping young-of-the-year (YOY) SMB from growing to adulthood. The study provides evidence to what Beyond Pesticides suspected back in May, when PFBC confirmed that a rare malignant tumor was found for the first time on a SMB caught by an angler back in the summer of 2014. Though the findings at the time did not point to a specific […]

(Beyond Pesticides, November 18, 2015) Last week, the European Union’s (EU) European Food Safety Agency (EFSA) announced its determination that the popular herbicide glyphosate is “unlikely to pose a carcinogenic hazard to humans.” This is in direct contrast with findings released  earlier this year by  the World Health Organization’s (WHO) International Agency for Research on Cancer (IARC), which classified glyphosate a ”˜probable carcinogen.’  However, these seemingly conflicting conclusions from these premier scientific agencies are put into perspective by knowing that EFSA’s report is limited in that it reviewed glyphosate alone, unlike IARC which reviewed glyphosate and its formulated products (Monsanto’s Roundup) which are more relevant for evaluating risks to human health. In light of the March 2015 IARC findings —listing glyphosate as a probable carcinogen due to  sufficient evidence of carcinogenicity  based on laboratory studies, the European Commission requested EFSA consider glyphosate’s potential carcinogenicity. In its report released November 12, 2015, EFSA concludes that “glyphosate is unlikely to pose a carcinogenic hazard to humans and the evidence does not support classification with regard to its carcinogenic potential..” However, the agency notes that there are “several reasons explaining the diverging views” from IARC’s earlier conclusion. The most important difference is that […]

(Beyond Pesticides, November 10, 2015) Exposure to organochlorine chemicals, such as DDE and PCBs, is linked to increased rates of sperm abnormalities that may lead to fertility problems, according to a new study published in the journal Environmental Health Perspectives. This is the latest study in a long line of research implicating endocrine (hormone)-disrupting chemicals in reproductive diseases. Researchers investigated this issue by observing the blood serum and sperm quality of 90 men, aged 22-44, participating in health studies in the Faroe Islands, an archipelago under  Denmark’s control that is  located between Iceland, the UK and Norway. Faroe islanders consume a high seafood diet that often consists of pilot whale, integral historically as a  food source for the Faroese people. However, this practice exposes the Faroese to higher than average levels of environmental contaminants. For the study, data on umbilical cord blood and blood serum at age 14 was available for 40 of the participants, allowing a researchers to measure lifetime impacts. Faroese participants were screened for sperm aneuploidy, a condition which usually involves an abnormal number of X or Y chromosomes in sperm, and is suspected as contributing to congenital abnormalities and up to 50% of early pregnancy losses. […]

(Beyond Pesticides, November 6, 2015) New York State Senator Tim Kennedy (D-NY) has called for a statewide ban on triclosan, one of the most prevalent antibacterial compounds found in common household products. Minnesota is the only state to have passed a triclosan  ban. If passed, the New York Bill (Bill S6070) would prohibit the sale of cleaning products containing triclosan, triclocarban, or derivatives of similar antibacterial compounds, and mark a clear victory for human health and safety interests within the state. Triclosan has been used for over 30 years in the U.S., mostly in a medical setting, but more recently in consumer products. Beyond Pesticides has generated extensive documentation  of the potential human and environmental health effects of triclosan and its cousin triclocarban, called on manufacturers to stop using triclosan in its products and retailers to stop carrying these products, and previously petitioned the Environmental Protection Agency (EPA) for the cancellation of registered products that contain the antibacterial pesticide. In May 2015, EPA issued its long-awaited response to the Citizen Petition filed by Beyond Pesticides and Food & Water Watch, denying the request. When introduced to the market in 1972, triclosan was confined to hospital and health care settings. Since […]

(Beyond Pesticides, October 6, 2015) Last week, the International Federation of Gynecology and Obstetrics (FIGO) released a statement encouraging broad-based policy measures that prevent exposure to toxic environmental chemicals. “The global health and economic burden related to toxic environmental chemicals is in excess of millions of deaths and billions of dollars every year,” the report unequivocally states. FIGO’s statement follows a similar call to action from the American College of Obstetricians and Gynecologists in 2013 and the American Academy of Pediatrics in 2012. The piece lays out broad themes surrounding exposure to toxic chemicals, including issues of environmental justice, prenatal exposure and subsequent health effects, and overall global health and economic burden. Based on these impacts, several recommendations are submitted for obstetricians, gynecologists, midwives, women’s health nurse practitioners, nurses, and other health professionals to follow to achieve a goal of “prevention for all.” FIGO highlights how people of low-income, particularly in poverty-stricken countries, bare a higher burden of toxic exposure than richer nations. “[A]t every stage of development, the consequences of exposure to toxic chemicals —including morbidity and mortality, loss of family income and productivity, and environmental degradation— are disproportionately borne by people with low incomes,” the piece states. FIGO […]

(Beyond Pesticides, August 7, 2015) Parental exposure to environmental stressors, such as pesticides, before a child is conceived can alter the way genes are expressed in the mother and father, ultimately harming the child’s health when those genes are passed down to the next generation, according to an article published in the Endocrine Society’s journal Endocrinology. “In regard to environmental stressors, a good start lasts a lifetime,” said Philippe Grandjean, M.D., Ph.D. Dr. Grandjean is Professor of Environmental Medicine at the University of Southern Denmark and Adjunct Professor of Environmental Health at the Harvard University’s T.H. Chan School of Public Health and an author of the article. “Unfortunately, current testing paradigms do not properly assess the impact of risk factors during vulnerable exposure windows. Without new policies and guidelines, we cannot have a universal healthy start for children.” The article, titled Life-Long Implications of Developmental Exposure to Environmental Stressors: New Perspectives, summarizes the newest science and key insights from the 4th  Conference on Prenatal Programming and Toxicity (PPTOX IV). More than 300 people attended the event in Boston, MA in October 2014. The meeting featured poster presentations discussing the impact of chemical, physical, and biological environmental stressors on the interconnected […]

(Beyond Pesticides, July 6, 2015) With the release of its  Tier 1 screening results  for the first 52 pesticide chemicals (active and inert ingredients) evaluated under  the Endocrine Disruptor Screening Program (EDSP), the U.S. Environmental Protection Agency (EPA) is at odds with a large body of scientific evidence worldwide that identifies many of these chemicals, most notably the herbicides  2,4-D  and  atrazine,  as interacting with the endocrine system or acting as endocrine disruptors. Independent scientific data has shown these chemicals to interfere with the hormone system. EPA’s EDSP is a multi-step process used to ensure that exposure to chemicals does not result in adverse human health and environmental effects that canoccur from the disruption of hormones. The two-tiered screening and testing system requires that EPA identify which chemicals are able to interact with the endocrine system, specifically with three hormonal pathways — estrogen, androgen, and thyroid — in Tier 1. Tier 2 is designed to go one step further, requiring EPA to determine endocrine effects across taxa (e.g. mammals, birds, amphibians, and invertebrates) as well as potential effects on non-endocrine systems (e.g. neurological, immunological, hepatic, and renal).  According to EPA, Tier 1 screening data are the best way to determine […]

(Beyond Pesticides, June 24, 2015) The International Agency for Research on Cancer (IARC) has found that there is some evidence in experimental animals that the popular herbicide, 2,4-D, is linked to cancer and now classifies it as a Group 2B, “possibly carcinogenic to humans.” IARC also classified lindane, used commonly in the U.S. as a topical lice treatment, in Group 1,“carcinogenic to humans” based on sufficient evidence in humans with the onset of non-Hodgkin lymphoma (NHL). These latest cancer findings come just months after the agency classified the world’s most widely used herbicide, glyphosate (Roundup), as “probably carcinogenic to humans,” raising public concerns on the lack of action from U.S. regulators. This month, 26 experts from 13 countries met at the World Health Organization’s (WHO) IARC in Lyon, France to assess the carcinogenicity of the insecticide lindane, the herbicide 2,4-D, and insecticide DDT. The findings are published in the Lancet. The new IARC findings come months after the agency classified glyphosate, the ingredient in the popular Roundup weed killer, as a Group 2A “probable” carcinogen, citing sufficient evidence of carcinogenicity based on laboratory studies. This decision sparked renewed calls for the U.S. Environmental Protection Agency (EPA) to take action on […]

(Beyond Pesticides, June 19, 2015) A new study directly links exposure to dichlorodiphenyltrichloroethane (DDT) in utero to the development of breast cancer later in life. Published in the Journal of Clinical Endocrinology and Metabolism, the study looked at data that were taken from a California program that  evaluated  samples from women during 1960s, when DDT use was popular. DDT is known to be an endocrine disruptor, and is linked to serious health effects. Although DDT has been banned for many years, residues still linger in certain areas of the U.S. and continue to cause environmental and health hazards. The recent study, titled DDT Exposure in Utero and Breast Cancer,  focuses on 118 mothers who were members of Kaiser Foundation Health Plan from 1959-1967 and had daughters that were diagnosed with breast cancer by their 50s. Stored blood samples from these mothers gave researchers an idea of how much DDT they were exposed to during pregnancy or soon after giving birth. They found that elevated levels of DDT in the mother’s blood led to a four-fold increase in the daughter’s risk of developing breast cancer. Among those with cancer, 83% had a form of cancer called estrogen positive breast cancer, which […]

(Beyond Pesticides, June 16, 2015) France’s Ecology Minister Segolene Royal announced Sunday a  call to  stop  the sale of the popular Monsanto herbicide Roundup (glyphosate) from garden centers. The announcement comes just a couple of  months after the active ingredient, glyphosate, was classified in March as “probably carcinogenic to humans” by the United Nation’s International Agency for Research on Cancer (IARC). “France must be on the offensive with regards to the banning of pesticides,” Royal said on French television. “I have asked garden centers to stop putting Monsanto’s Roundup on sale” in self-service aisles, she added. The announcement comes after a request by French consumer association CLCV (Consumption, Housing and Environment – Consommation, Logement et Cadre de vie)  to French and European officials to stop selling glyphosate-based products to amateur gardeners. Royal also announced last week that from January 2018 onwards, phytosanitary products —used to control plant diseases— would only be available to amateur gardeners “through an intermediary or a certified vendor.” Glyphosate is touted as a “low toxicity” chemical and “safer” than other chemicals by EPA and industry and is widely used in food production and on lawns, gardens, parks, and children’s playing fields. However, IARC’s new classification of […]

(Beyond Pesticides, May 28, 2015) The same day that trade representatives from United States met with Secretary-General Catherine Day of the European Commission (EC), she sent a letter to the EC’s Environment Director-General Karl Falkenberg telling him to scrap draft criteria that could have led to a ban on over 30 endocrine (hormone) disrupting chemical (EDCs) in the European Union (EU). As reported by The Guardian, with resources obtained by Pesticide Action Network- Europe (PAN-Europe), the U.S. Chambers of Commerce and European-based chemical manufacturers (including Dupont, Bayer, and BASF) pushed to change the EC’s criteria for evaluating EDCs because they fear it would impede EU-US negotiations on  the Transatlantic Trade and Investment Partnership (TTIP). Two regulations, one concerning “plant pest protectants” (EU 1107), and another on biocidal products (EU 528), should prohibit from use chemicals categorized as having endocrine disrupting properties that may cause adverse effects in humans. However, last year, when the EC released a roadmap for evaluating EDCs, recommendations fell far short of what health advocates assert that EU regulations require. Earlier this year, the Guardian reported that a scientific paper that would have adequately established ways to identify problematic EDCs was suppressed by EU officials at the […]

(Beyond Pesticides, May 7, 2015) The Pennsylvania Fish and Boat Commission (PFBC) has confirmed that a rare malignant tumor was found on a smallmouth bass caught in the Susquehanna River by an angler late last summer. The finding was confirmed by two independent laboratory tests, including the U.S. Fish and Wildlife Service (FWS) and the Aquatic Animal Health Laboratory at Michigan State University.  Although it only represents one individual fish from the overall population, it provides additional evidence —which includes the prevalence of intersex fish discovered last summer”” that the health of the fish community residing in the river is being compromised, according to PFBC executive director John Arway. Though the findings do not point to a specific cause for the cancer found on the smallmouth bass (SMB), agricultural pesticides, particularly endocrine disrupting chemicals, that have been found in the watershed, likely play a part in the rampant disease issues in SMB in the Susquehanna River. “As we continue to study the river, we find young-of-year and now adult bass with sores, lesions and more recently a cancerous tumor, all of which continue to negatively impact population levels and recreational fishing,” Mr. Arway said. “The weight-of-evidence continues to build a […]

(Beyond Pesticides, April 27, 2015) Last week, the United States Department of Agriculture (USDA) announced initiatives and energy programs to reduce greenhouse gas emissions, increase carbon sequestration, and expand renewable energy production in the agricultural and forestry sectors, but failed to stress the importance of moving away from chemical-intensive  agriculture toward organic methods. While the announcement doesn’t specifically mention “organic,” the meaning is still clear: chemical-based agricultural practices have contributed to climate change through heavy use of fossil fuels —both directly on the farm and in the manufacturing of pesticides and fertilizers— and through degradation of the soil, which releases carbon. Now, USDA is suggesting the use of conservation tilling, or no-till practices, along with cover cropping and natural management of organic inputs to the soil — in other words, organic agriculture. USDA outlined ten “building blocks” that aim to lead us away from climate change. The first two of these ten could, if interpreted from an organic practice perspective,  address the necessity to change  chemical-intensive agricultural practices. The first “building block” is soil health. The stated goal is to improve soil resilience, therefore increasing productivity, by promoting conservation tillage or no-till farming. The initiative suggests planting cover crops, planting […]

(Beyond Pesticides, March 13, 2015) Exposure to endocrine (hormone) disrupting chemicals (EDC) results in approximately € 150 billion ($162 billion) in health care costs in the European Union each year, according to panels of scientists tasked by the EU Commission to study their impact. “The shocking thing is that the major component of that cost is related to the loss of brain function in the next generation,” Philippe Grandjean, M.D. of Harvard University, one of the report’s authors, told the Guardian. EDCs, contained in common household products such as detergents, disinfectants, furniture, plastics, and pesticides, interfere with the body’s hormone system either by mimicking naturally produced hormones, blocking hormone receptors in cells, or effecting the transport, synthesis, metabolism or excretion of hormones. These impacts can result in devastating effects on one’s health, including behavioral and learning disorders, such as Attention Deficit Hyperactivity Disorder (ADHD), birth defects, obesity, early puberty, infertility, cardiovascular disease, and childhood and adult cancers. Nearly 100 percent of people have detectable amounts of EDCs in their bodies, according to the introductory guide to EDCs published by the Endocrine Society and IPEN. “Our brains need particular hormones to develop normally —the thyroid hormone and sex hormones like testosterone […]

(Beyond Pesticides, February 5, 2015) A brewing  battle in the European Union (EU) over removing from the market  Endocrine Disrupting Chemicals (EDC)s has  heated up. An investigative report in  The Guardian  reveals that a European Union (EU) scientific paper, prepared to assist in the development of new mandatory EDC risk assessment standards, was never made public. According to the report, EU Commission sources say the release of the paper was quashed as a result of chemical industry pressure and political influence. At the core of the debate lies two EU regulations, one concerning biocidal products (EU 528/2012) and the second on “plant pest protectants” (EU 1107/2009). Both of these regulations required the EU Commission to produce draft measures concerning specific scientific criteria for the determination of endocrine disrupting properties by December 14, 2013. Under the regulations, chemicals within the biocidal and plant pest protectant categories that are  categorized as having endocrine disrupting properties that may cause adverse effects in humans would be prohibited from use in the market place. As noted in the purpose and subject matter of the biocidal regulations, “The purpose of [the] Regulation is to improve the functioning of the internal market through the harmonization of the […]

(Beyond Pesticides, January 30, 2015) Extensive exposure to common chemicals may be linked to an earlier start of menopause, according to a new study out of Washington University School of Medicine in St. Louis. Researchers of the study found that women whose bodies have high levels of these chemicals, including three pesticides, experience menopause two to four years earlier than women with lower levels of the chemicals. The pesticides found to have a significant correlation with an early start in menopause were p,p’-DDE (a metabolite of DDT), β-hexachlorocyclohexane (a byproduct of the production of lindane), and mirex. All three pesticides are organochlorine insecticides or their breakdown products that have been banned for use  in the U.S., but continue to persist in the environment and in the food chain. The study, Persistent Organic Pollutants and Early Menopause in U.S. Women, published this week in the journal PLoS ONE, investigates the link between levels in blood and urine of 111 endocrine-disrupting chemicals (EDCs), or chemicals that interfere with the body’s hormonal activity, and focused on known reproductive toxicants or persistent environmental contaminants. The findings suggest a significant association between 15 chemicals —nine polychlorinated biphenyls (PCBs, which are industrial products), three pesticides, two […]

(Beyond Pesticides, December 16, 2014) Beyond Pesticides is sad to say goodbye to a dear friend and colleague, Theo Colborn, who at the age of 87, passed away on Sunday, December 14 at home surrounded by her family. Dr. Colborn is author of the groundbreaking book Our Stolen Future, president of The Endocrine Disruption Exchange (TEDX) and Professor Emeritus at the University of Florida, Gainesville. She is the author of numerous scientific publications about compounds that interfere with hormones and other chemical messengers that control development in wildlife and humans. Her incisive research has demonstrated that endocrine disrupting chemicals alter development of the fetus in the womb by interfering with the natural hormonal signals directing fetal growth. Her work has prompted the enactment of new laws around the world. Dr. Colborn was presented with Beyond Pesticides’ highest honor, its Dragonfly Award, at the organization’s 25th Anniversary Gala in 2006, “For tireless dedication advancing knowledge and action to protect health and the environment.” Upon accepting the award, she said to those who chose her as the recipient that she would do her best not to let them down, and she hasn’t. One year later, she was honored by Time magazine as […]

(Beyond Pesticides, August 19, 2014) Newly released documents from the U.S. Food and Drug Administration (FDA) reveals that regulators expressed concerns over the safety of triclosan in Colgate Total toothpaste during the product’s registration in the mid-1990s. This information was provided to the public by FDA after a Freedom of Information Act request by the Natural Resources Defense Council (NRDC), and was posted on the agency’s website after inquiries from Bloomberg News. In addition to health effects previously identified by Beyond Pesticides, these documents raise concerns about the use of triclosan as an anti-gingivitis agent in toothpaste; a use which is not currently under scrutiny as FDA conducts its long-awaited health review of the chemical. Although FDA is requiring manufacturers of triclosan-containing soaps to prove that their products are not hazardous to humans and more effective than regular soap and water, triclosan formulated in toothpaste was not subject to a similar requirement as FDA had indicated that the chemical is effective as an anti-gingivitis agent. Colgate Total is the only brand of toothpaste on the market that still contains triclosan; GlaxoSmithKline, producer of Aquafresh and Sensodyne, removed triclosan from its toothpaste in 2009. And a focus on safer products seems […]

(Beyond Pesticides, August 12, 2014) The presence of triclosan in soaps and consumer products ranging from cutting boards to pencils means constant exposure to a chemical linked to a wide range of adverse health effects. New data to be presented at the 248th National Meeting and Exposition of the American Chemical Society, the world’s largest scientific society, reveals that 100% of pregnant women in a multiethnic urban population in Brooklyn, New York tested positive for triclosan in their urine. In half of the pregnant women tested, the chemical also showed up in umbilical cord blood. “We looked at the exposure of pregnant women and their fetuses to triclosan and triclocarban, two of the most commonly used germ-killers in soaps and other everyday products,” says study co-author Benny Pycke, Ph.D at Arizona State University. “We found triclosan in all of the urine samples from the pregnant women that we screened. We also detected it in about half of the umbilical cord blood samples we took, which means it transfers to fetuses.” In 2004, Beyond Pesticides published The Ubiquitous Triclosan, sounding the alarm on the rising use of an antibacterial chemical never adequately evaluated for adverse effects by the U.S. Food and […]

(Beyond Pesticides, July 29, 2014) A recent rise in drug resistant human pathogenic fungi may be fueled by the use of fungicides (pesticides that kill fungi) on agricultural fields, according to research led by Manchester University in the United Kingdom. Aspergillus, the genus of common soil-dwelling fungi analyzed by researchers, include an incredibly diverse group of mold species. Although some provide important commercial uses (such as in the production of citric acid, for instance), many species are pathogenic in humans, and can result in life-threatening lung infections. The rise of cross-resistant fungi is a serious concern for sensitive individuals with weakened immune systems, such as transplant patients, asthmatics, and those with leukemia. In the study, Occurrence of azole-resistant species of Aspergillus in the UK environment, UK scientists collected hundreds of samples across the country. Although no resistant strains were found in inner city locations, 1.7% of samples from rural agricultural areas had markers for drug resistance. However, previous research conducted in India in 2012 found resistant isolates in a number of urban and agricultural sites, including the soil beneath cotton trees and rice paddy fields, but also in air samples from hospital wards and even in the soil from flower […]

(Beyond Pesticides, July 15, 2014) More nutritional antioxidants, far fewer toxic pesticides; those are the results of a comprehensive meta-analysis on organic foods published yesterday in the British Journal of Nutrition.  Led by Carlo Leifort, Ph.D, at England’s Newcastle University, the analysis is a scientific rebuttal to a previous Stanford University review published in 2012, which found that there was little difference between the nutritional content of organic food over conventionally grown produce. Both studies found there to be fewer pesticides in organic products. While Stanford University’s review only looked at 200 studies, Dr. Leifert and his team of researchers expanded the scope of their meta-analysis to 343 studies, and also employed more robust analytic tools by analyzing the standardized mean differences of the data from the various studies. It shows very clearly how you grow your food has an impact,” said Dr. Leifert to The New York Times. “If you buy organic fruits and vegetables, you can be sure you have, on average, a higher amount of antioxidants at the same calorie level.” Antioxidants, compounds such as phenolic acids, flavanones, stilbenes, flavones, flavonols and anthocyanin, have been linked to lower risks of cancer and other diseases. For many, news […]

(Beyond Pesticides, July 7, 2014) A study led by the U.S. Geological Service (USGS) finds intersex fish in three watersheds of Pennsylvania and shows strong connections between these occurrences and increased pollution in waterways from endocrine-disrupting chemicals. The study, Reproductive Health Indicators of Fish from Pennsylvania Watersheds: Associations with Chemicals of Emerging Concern, examined three species of fish in three separate watersheds of Pennsylvania to assess whether characteristics caused by hormones and hormone-mimicking compounds, such as immature eggs in male fish, were present. In aquatic environments, the presence of these intersex characteristics is widely used as a biomarker for assessing exposure to estrogenic chemicals, as well as anti-androgenic chemicals which inhibit development of male characteristics. Male smallmouth bass from all sites sampled had immature eggs in their testes; prevalence was lowest in the Ohio drainage, intermediate in the Delaware and highest in the Susquehanna. While these findings were disturbing in and of themselves, the study was also able to draw a connection to the increased presence of intersex characteristics and areas of high agricultural use. “The prevalence and severity of the immature eggs in smallmouth bass corresponded with the percent of agricultural land use in the watershed above the collection […]

(Beyond Pesticides, July 2, 2014) According to a new study, few obstetricians offer their pregnant  patients advice on how to avoid environmental toxins that might harm their babies, even though doctors recognize that exposure to chemicals like pesticides, bisphenol-A (BPA), and metals can affect  a pregnancy. The study recommends that the medical community improve medical education and training, develop recommendations for prevention and less toxic alternatives, as well as lend support to policy change. The first of its kind study of prenatal counselling, published in the journal  PLOS ONE, Counseling Patients on Preventing Prenatal Environmental Exposures – A Mixed-Methods Study of Obstetricians, found that U.S. obstetricians and gynaecologists feel they lack the medical education and training, and evidence-based guidelines and tools for communicating potential environmental risks to patients. Exposure to environmental toxins, the researchers from the University of California, San Francisco (UCSF) found, is rarely discussed with pregnant patients, even though a national survey shows that 80 percent of physicians agree they should play a part in reducing patients’ exposure to toxins. But, of the 2,500 respondents, only one in five routinely asked  their  patients about these exposures, and just one in 15 said they received training on the harmful […]