(Beyond Pesticides, October 6, 2015) Last week, the International Federation of Gynecology and Obstetrics (FIGO) released a statement encouraging broad-based policy measures that prevent exposure to toxic environmental chemicals. “The global health and economic burden related to toxic environmental chemicals is in excess of millions of deaths and billions of dollars every year,” the report unequivocally states. FIGO’s statement follows a similar call to action from the American College of Obstetricians and Gynecologists in 2013 and the American Academy of Pediatrics in 2012. The piece lays out broad themes surrounding exposure to toxic chemicals, including issues of environmental justice, prenatal exposure and subsequent health effects, and overall global health and economic burden. Based on these impacts, several recommendations are submitted for obstetricians, gynecologists, midwives, women’s health nurse practitioners, nurses, and other health professionals to follow to achieve a goal of “prevention for all.” FIGO highlights how people of low-income, particularly in poverty-stricken countries, bare a higher burden of toxic exposure than richer nations. “[A]t every stage of development, the consequences of exposure to toxic chemicals —including morbidity and mortality, loss of family income and productivity, and environmental degradation— are disproportionately borne by people with low incomes,” the piece states. FIGO […]

(Beyond Pesticides, October 05, 2015) According to a Yale University study, prenatal exposure to the widely used agricultural pesticide chlorpyrifos is linked to tremors — involuntary contraction or twitching of muscles — in childhood. Chlorpyrifos, a broad-spectrum chlorinated organophosphate insecticide also known as Dursban, may also affect the cardiovascular and respiratory systems and is acutely toxic to bees, birds, mammals, and aquatic life. The study, titled Prenatal exposure to the organophosphate pesticide chlorpyrifos and childhood tremor  and published in the journal Neurotoxicology, measured the presence of chlorpyrifos in umbilical cord blood samples in 263 low-income, inner-city minority children. In 2001, the U.S. Environmental Protection Agency (EPA) banned residential use of chlorpyrifos, which was prominent in urban areas at the time. However, the study participants  —263 minority mothers  and their children, all from low income  communities in New York  City— were assembled in 1997,  before the ban was imposed. In  1997, the initial measure of each  child’s prenatal exposure to CPF  was taken from umbilical cord  blood. The children were then followed until approximately 11 years of age, after which they underwent a neurophysical assessment, which included a short drawing test. Researchers found that compared to all other children, those who […]

(Beyond Pesticides, September 22, 2015) A meta-analysis presented at the annual meeting of the European Association for the Study of Diabetes in Sweden concludes that exposure to pesticides is associated with an increased risk of diabetes. Although diabetes is long-suspected as involving an interplay between genetics and environmental factors, emerging research is revealing that contaminants like pesticides may play an important role in the pathogenesis of the disease. These findings add to a growing body of evidence demonstrating that pesticides play a key role in the development of a wide range of all-too-common diseases in the 21st century. To assess the association between pesticide exposure and diabetes, the recent research, Association between diabetes and exposure to pesticides: a systematic review and meta-analysis, examine 21 relevant studies comprising over 66,000 people. Most studies determined pesticide exposure through urinary or blood biomarker analysis, a highly reliable method of testing body burden. Exposure to any pesticide is linked to a 61% increase in diabetes. When looking specifically at type 2 diabetes, researchers found similar results, with any pesticide exposure increasing risk of developing the disease by 64%. However, researchers found that, although on the whole pesticides increased the chance of any diabetes diagnosis, […]

(Beyond Pesticides, September 15, 2015) A study released this week in the journal Pediatrics finds that children’s exposure to pesticides in and around the home results in an increased risk of developing certain childhood cancers. Researchers made their findings through a meta-analysis, reviewing 16 epidemiological studies published since 1993 on the link between childhood cancer and pesticide exposure. Based on their findings, the authors of the study suggest “”¦public health policies should be developed to minimize childhood exposure to pesticides in the home,” and that “[e]very effort should be made to limit children’s exposure to pesticides.” While most meta-analytical reviews previously conducted on the link between pesticides and childhood cancer looked at parental exposure or agricultural exposure, the current study from scientists at the Harvard T.H Chan School of Public Health focuses in on residential exposure in and around a child’s home. Authors found that cancer risks were connected most closely to the type of pesticide used and the location where it was applied. For example, while residential herbicide use was associated with an increased risk of leukemia, the link between outdoor insecticide use and childhood cancers was not found to be statistically significant. However, exposure to insecticides inside the […]

(Beyond Pesticides, September 10, 2015) Last week, California Environmental Protection Agency’s Office of Environmental Health Hazard Assessment (OEHHA) announced that it intended to list glyphosate (Roundup) and three other chemicals as cancer-causing chemicals under California’s  Safe Drinking Water and Toxic Enforcement Act of 1986 (Proposition 65). Glyphosate  is a phosphanoglycine herbicide that inhibits an enzyme essential to plant growth. Under California law, Proposition 65 requires that certain substances identified by the International View postAgency for Research on Cancer (IARC) be listed as known cancer-causing chemicals. In March, a study by the IARC classified glyphosate as a Group 2A material, which means that the chemical is carcinogenic based on sufficient evidence of carcinogenicity in experimental animals. The agency considered the findings from an EPA Scientific Advisory Panel report, along with several recent studies in making its conclusion. However, industry supporters of glyphosate all over the globe are conducting their own studies to attempt to prove that it is not a carcinogen. These studies, like one by German Federal Institute for Risk Assessments (BfR), are based almost solely on industry science and classified industry reports, each of which might not consider critical variables. With more glyphosate-focused studies being released, the growing evidence […]

(Beyond Pesticides September 9, 2015) A young Florida boy and his family are reeling after a routine termite treatment resulted in a devastating outcome. Ten-year-old Peyton McCaughey of Palm City, Florida has been in the hospital for weeks following a severe reaction to chemicals used to fumigate his family’s home. According to news reports, the  fumigation was performed by Sunland Pest Control, a subcontractor of Terminix. The Florida Department of Agriculture has since issued a “Stop Work Order” while it  investigates the company in collaboration with the Environmental Protection Agency (EPA) and the state Department of Health. After returning to their home hours after the Terminix subcontractor told them it was safe to enter, the whole family became very ill. While the parents and the 7-year-old daughter recovered, the young boy’s condition continued to worsen. “He was having some uncontrollable muscle movements, couldn’t stand up, couldn’t speak, so they took him to a local walk-in and the doctor quickly recognized it was probably poisoning from a treatment,” said Peyton’s uncle, Ed Gribben. Current reports indicate that the boy has likely suffered brain damage and has lost all muscle control, rendering him unable to stand or speak. He remains in a […]

(Beyond Pesticides, September 1, 2015) A  research study published in the journal Environmental Health  links chronic, ultra-low dose exposure to glyphosate in drinking water to adverse impacts on the health of liver and kidneys. The study, Transcriptome profile analysis reflects rat liver and kidney damage following chronic ultra-low dose Roundup exposure, is the latest in a string of data showing unacceptable risks resulting from exposure to glyphosate and products formulated with the chemical, like Monsanto’s Roundup. Researchers conducted the study by exposing rats to minute (0.1 parts per billion) doses of Roundup in drinking water for a period of 2 years. After noting tissue damage and biochemical changes in the blood and urine of exposed animals that was indicative of organ damage, the authors attempted to confirm their findings by analyzing changes in gene expression within liver and kidneys. Of 4,447 gene transcript clusters analyzed by scientists, 4,224 showed some alteration. Compared to non-exposed rats, “[t]here were more than 4,000 genes in the liver and kidneys whose levels of expression had changed,” said Michael Antoniou, PhD, senior author of the study to Environmental Health News. Authors indicate that the changes in gene expression observed in the study are associated with […]

(Beyond Pesticides, August 27, 2015) Last week, Philip J. Landrigan, M.D., and Charles Benbrook, Ph.D., released a perspective article, GMOs, Herbicides, and Public Health, in the New England Journal of Medicine  that outlines  the hazards associated with food residues of  elevated pesticide use in the production  of genetically engineered (GE) crops. While mainstream media continuously misses the central issue  in the GE debate by asserting that these crops are merely an extension of selective breeding and effect a reduction in pesticide use, the authors  focus on  the significance of the actual increase in herbicide use and weed resistance in herbicide-tolerant crops. Drs. Landrigan and Benbrook offer two main recommendations in their article: the U.S. Environmental Protection Agency (EPA) should delay implementation of its decision to permit the use of Enlist Duo (the 2,4-D herbicide used with  Monsanto-engineered GE herbicide-tolerant  crop), and  the U.S. Food and Drug Administration (FDA) should  require labeling of GE foods and couple it with adequately funded, long-term postmarketing surveillance. Dr. Landrigan, Dean for Global Health at Mount Sinai School of Medicine, is an epidemiologist and pediatrician and one of the world’s leading advocates of children’s and environmental health. Dr. Benbrook is a research professor at the […]

(Beyond Pesticides, August 19, 2015) Local fogging for  mosquito control turned tragic for a Palo Alto, California beekeeper who lost hundreds of honey bees from his backyard hives. The beekeeper, who also produces organic honey, now fears his honey is contaminated. The fogging, which occurred last month, was in response to positive tests for West Nile virus in mosquito samples. Many mosquito control pesticides are toxic to honey bees and given the declining populations of pollinators, vector control officials are being asked to carefully consider the risks associated with pesticide spraying. According to the local NBC affiliate, beekeeper Rondolph Tsien believes he was not given sufficient time to protect his bees from the mosquito fogging and, despite trying to cover his hives with a tarp to protect his bees from drifting pesticides, many were lost. A mosquito sample tested positive for West Nile virus about one mile from Mr. Tsien’s home, putting his property in the catchment area for fogging. Mr. Tsien worries the surviving bees will produce contaminated honey that can no longer be labeled organic. A Santa Clara County Vector Control representative stated during an interview that the county uses  an “extremely low dose” of pesticides during fogging […]

(Beyond Pesticides, August 11, 2015) The U.S. Environmental Protection Agency (EPA) is proposing new standards for pesticide applicators who apply “restricted use” pesticides, requiring an increased level of training, a minimum age requirement for applicators, and basic literacy. The proposal will soon be available for public comment. Encompassing the highly acutely toxic  pesticides, “restricted use” pesticides are not available for purchase by the general public, and may only be applied by a certified pesticide applicator or an individual working under their direct supervision (which does not require on-site supervision). To highlight the danger associated with the use of these chemicals, EPA estimates that its modest changes in oversight will save $80.5 million, directly attributable to fewer acute pesticide incidents to people. Jim Jones, EPA Assistant Administrator for the Office of Chemical Safety and Pollution Prevention, hosted a conference call, attended by Beyond Pesticides staff, in which he provided an overview of the proposed changes. “We are committed to keeping our communities safe, protecting our environment and protecting workers and their families,” said Mr. Jones. “By improving training and certification, those who apply these restricted use pesticides will have better knowledge and ability to use these pesticides safely.” Although EPA’s actions […]

(Beyond Pesticides, August 7, 2015) Parental exposure to environmental stressors, such as pesticides, before a child is conceived can alter the way genes are expressed in the mother and father, ultimately harming the child’s health when those genes are passed down to the next generation, according to an article published in the Endocrine Society’s journal Endocrinology. “In regard to environmental stressors, a good start lasts a lifetime,” said Philippe Grandjean, M.D., Ph.D. Dr. Grandjean is Professor of Environmental Medicine at the University of Southern Denmark and Adjunct Professor of Environmental Health at the Harvard University’s T.H. Chan School of Public Health and an author of the article. “Unfortunately, current testing paradigms do not properly assess the impact of risk factors during vulnerable exposure windows. Without new policies and guidelines, we cannot have a universal healthy start for children.” The article, titled Life-Long Implications of Developmental Exposure to Environmental Stressors: New Perspectives, summarizes the newest science and key insights from the 4th  Conference on Prenatal Programming and Toxicity (PPTOX IV). More than 300 people attended the event in Boston, MA in October 2014. The meeting featured poster presentations discussing the impact of chemical, physical, and biological environmental stressors on the interconnected […]

(Beyond Pesticides, August 4, 2015) Nearly every food available for purchase at the U.S. Congressional Dining Hall contains detectable levels of neonicotinoids (neonics), chemical insecticides implicated in the global decline of wild and managed pollinators. The results of a new study, performed by the American Bird Conservancy (ABC) and the Harvard T.H. Chan School of Public Health, reveals how reliance on these toxic chemicals can both directly and indirectly affect  our food supply. Authors of the study hope the results will build Congressional support for the Saving America’s Pollinators Act of 2015, which would suspend the use of neonics while an independent review analyzes the chemical’s effects to birds, pollinators, and other wildlife. Researchers for the study conducted two rounds of food testing, the first in January, and the second in May 2015. Approximately half of samples were taken from the House Longworth Cafeteria and half from Senate Dirksen Cafeteria in Washington, D.C. In total, 66 food samples were tested for the presence of neonicotinoids. Of that, 60, or 91% of samples tested positive for one neonic, and 47, or 71% of samples had two or more neonics present. “We were surprised to find that most foods contained multiple neonicotinoids, […]

(Beyond Pesticides, July 22, 2015) Months after the World Health Organization (WHO) formally associated the world’s most widely used herbicide  -glyphosate (Roundup)- with cancer, one of the world’s leading experts on cancer risk, and co-author of the WHO’s report, Christopher Portier, PhD, told a scientific briefing in London that the herbicide can damage human DNA, which could result in increased cancer risks. This finding comes on the heels of a call by the Soil Association for a United Kingdom (UK) ban on the use of glyphosate after finding residues of the chemical in bread. Earlier this spring, the WHO’s International Agency for Research on Cancer (IARC) classified glyphosate as Group 2a “probable” human carcinogen based on sufficient evidence of carcinogenicity in laboratory animals. Since then industry has hit back defending its champion product, even attempting to undercut the WHO’s findings with an industry-based  assessment that reached the opposite conclusion, based on classified industry reports.  Now an internationally recognized scientist, Dr.  Portier, former associate director, National Institute of Environmental Health Sciences, (NIEHS) and director of the Office of Risk Assessment Research at NIEHS, reiterated WHO’s findings at the UK Soil Association scientific briefing in Westminster on July 15. During his presentation, […]

(Beyond Pesticides, July 20, 2015) In response to  the recent cancer classification of glyphosate (Roundup)  by the International Agency for Research on Cancer (IARC), the specialized cancer agency of the World Health Organization,  an industry-based  assessment has reached the opposite conclusion based on classified industry reports has concluded that Monsanto’s glyphosate is not carcinogenic.   According to The Guardian, the assessment by the German Federal Institute for Risk Assessments (BfR) is based almost solely on industry science and classified industry reports. Three scientists on Germany’s scientific panel on pesticides work for the pesticide industry. Monsanto objected earlier this year, when IARC announced in a preliminary report that glyphosate is a probable human carcinogen based on laboratory animal studies. BfR and IARC’s findings have been released during a pivotal time, as a decision on whether to extend the license for glyphosate’s use in Europe is currently pending, and these studies are sure to be incorporated into the decision making process. According to The Guardian, the European Food Safety Authority (EFSA) is delaying the release of its  opinion on glyphosate to take the full IARC report into account. The Guardian reports that BfR’s research relied heavily on unpublished reports provided by the […]

(Beyond Pesticides, July 8, 2015)  Last week, after decades of review and known toxic hazards, especially to children, the Environmental Protection Agency (EPA) accepted a proposed cancellation for  a number of indoor uses (including food establishments) and tolerances of propoxur, a carbamate insecticide known for its toxic effects to  children. EPA has received a Section 6(f) request under the Federal Insecticide, Fungicide and Rodenticide Act (FIFRA) from the registrant of propoxur to voluntarily cancel certain uses of the carbamate insecticide. The request from the manufacturer, Wellmark International, requests cancellation of  indoor aerosol, spray and liquid formulations of propoxur, indoor crack and crevice use, and all use in food-handling establishments.  EPA previously agreed to an April 1, 2016 phase out of propoxur in pet collars, but has continued to leave open these other avenues of exposure. The agency will begin accepting comments on its  proposal once it has been published in the Federal Register, which is expected to occur within 10 days of the prepublication signature date. It should be noted that EPA engages in lengthy negotiations with pesticide manufacturers, as is the case with propoxur (see recent announcement on chlorpyrifos), rather than pursuing rigorous regulatory standards through its cancellation or […]

(Beyond Pesticides, July 6, 2015) With the release of its  Tier 1 screening results  for the first 52 pesticide chemicals (active and inert ingredients) evaluated under  the Endocrine Disruptor Screening Program (EDSP), the U.S. Environmental Protection Agency (EPA) is at odds with a large body of scientific evidence worldwide that identifies many of these chemicals, most notably the herbicides  2,4-D  and  atrazine,  as interacting with the endocrine system or acting as endocrine disruptors. Independent scientific data has shown these chemicals to interfere with the hormone system. EPA’s EDSP is a multi-step process used to ensure that exposure to chemicals does not result in adverse human health and environmental effects that canoccur from the disruption of hormones. The two-tiered screening and testing system requires that EPA identify which chemicals are able to interact with the endocrine system, specifically with three hormonal pathways — estrogen, androgen, and thyroid — in Tier 1. Tier 2 is designed to go one step further, requiring EPA to determine endocrine effects across taxa (e.g. mammals, birds, amphibians, and invertebrates) as well as potential effects on non-endocrine systems (e.g. neurological, immunological, hepatic, and renal).  According to EPA, Tier 1 screening data are the best way to determine […]

(Beyond Pesticides, June 26, 2015) The agency responsible for chemical oversight in the European Union announced today that the antibacterial pesticide, triclosan, is toxic and bioaccumulative, and will be phased-out for hygienic uses and replaced by more suitable alternatives. According to the European Chemicals Agency (ECHA), “[N]o safe use could be demonstrated for the proposed use of Triclosan.” This decision has renewed calls for the U.S. Food and Drug Administration (FDA) and U.S. Environmental Protection Agency (EPA) to remove the chemical from the consumer market. EPA in May rejected a consumer petition that asked the agency to ban triclosan. “We applaud this step to protect public health and the environment,” said Jay Feldman, executive director, Beyond Pesticides. The ECHA opinion states that, “Risk was identified for both surface water and for the non-compartment specific effects relevant to the food chain (secondary poisoning).” ECHA believes that any further risk mitigation for triclosan is “not considered realistic.” Triclosan is an antimicrobial pesticide used in cosmetics, personal care products and treated plastics and textiles. It has been linked to hormone disrupting effects, bacterial and antibiotic resistance, cancer, and impacts on aquatic organisms. The chemical’s widespread consumer use raises concerns over necessity and efficacy. […]

(Beyond Pesticides, June 25, 2015) The U.S Environmental Protection Agency (EPA) announced Tuesday that it will analyze the effects of two of the most commonly used pesticides in the United States, glyphosate and atrazine, along with atrazine chemical-cousins propazine and simazine, for their impacts on 1,500 endangered plants and animals. The announcement marks an agreement between EPA and Center for Biological Diversity (CBD) on a proposed settlement amending a 2010 court order that  established a schedule to complete effects determinations for 75 chemicals on 11 species in the San Francisco (SF) Bay Area. According to EPA, 59 of the 75 pesticides have been evaluated and subject to  effects determinations, however for the remaining 16 pesticides, EPA and CBD agreed that it would be more efficient and environmentally significant to complete nationwide effects determinations, rather than limit their focus to the SF bay area listed species. The agency has committed to completing the assessments by June 2020. The initial lawsuit was filed by CBD in May 2007 against EPA for violating the Endangered Species Act by registering and allowing the use of scores of toxic pesticides in habitats for 11 San Francisco Bay Area endangered species without determining whether the chemicals […]

(Beyond Pesticides, June 24, 2015) The International Agency for Research on Cancer (IARC) has found that there is some evidence in experimental animals that the popular herbicide, 2,4-D, is linked to cancer and now classifies it as a Group 2B, “possibly carcinogenic to humans.” IARC also classified lindane, used commonly in the U.S. as a topical lice treatment, in Group 1,“carcinogenic to humans” based on sufficient evidence in humans with the onset of non-Hodgkin lymphoma (NHL). These latest cancer findings come just months after the agency classified the world’s most widely used herbicide, glyphosate (Roundup), as “probably carcinogenic to humans,” raising public concerns on the lack of action from U.S. regulators. This month, 26 experts from 13 countries met at the World Health Organization’s (WHO) IARC in Lyon, France to assess the carcinogenicity of the insecticide lindane, the herbicide 2,4-D, and insecticide DDT. The findings are published in the Lancet. The new IARC findings come months after the agency classified glyphosate, the ingredient in the popular Roundup weed killer, as a Group 2A “probable” carcinogen, citing sufficient evidence of carcinogenicity based on laboratory studies. This decision sparked renewed calls for the U.S. Environmental Protection Agency (EPA) to take action on […]

(Beyond Pesticides, June 23, 2015) After years of denial and obstruction, Air Force and Air Force Reserve veterans now have the chance to receive compensation for their exposure to the highly toxic herbicide Agent Orange on contaminated aircraft used after the Vietnam War. Affected veteran’s health issues stem from their time spent on UC-123 transport planes, which during the war were outfitted with spray equipment in the American military’s attempt to eliminate forest cover for Vietcong fighters. After the war, these aircraft were returned to use in the United States for basic transport operations such as cargo shipping and medical evacuation missions. However, these planes never underwent any form of decontamination or testing before being repurposed. Though the Agent Orange Act of 1991 stipulated medical care and disability coverage for sick veterans who  served in the Vietnam War and were exposed to Agent Orange, those who flew in contaminated post-war planes were deemed ineligible. Prior to this recent announcement from the Department of Veteran’s affairs, government officials asserted that the “dried residues” of Agent Orange were not likely to pose a health threat to aircraft crew. However, a study published by the National Academy of Sciences Institute of Medicine in […]

(Beyond Pesticides, June 19, 2015) A new study directly links exposure to dichlorodiphenyltrichloroethane (DDT) in utero to the development of breast cancer later in life. Published in the Journal of Clinical Endocrinology and Metabolism, the study looked at data that were taken from a California program that  evaluated  samples from women during 1960s, when DDT use was popular. DDT is known to be an endocrine disruptor, and is linked to serious health effects. Although DDT has been banned for many years, residues still linger in certain areas of the U.S. and continue to cause environmental and health hazards. The recent study, titled DDT Exposure in Utero and Breast Cancer,  focuses on 118 mothers who were members of Kaiser Foundation Health Plan from 1959-1967 and had daughters that were diagnosed with breast cancer by their 50s. Stored blood samples from these mothers gave researchers an idea of how much DDT they were exposed to during pregnancy or soon after giving birth. They found that elevated levels of DDT in the mother’s blood led to a four-fold increase in the daughter’s risk of developing breast cancer. Among those with cancer, 83% had a form of cancer called estrogen positive breast cancer, which […]

(Beyond Pesticides, June 15, 2015) A community in central Michigan is still dealing with the fallout of a pesticide company that produced DDT nearly half a century ago. St. Louis, MI, a city about one hour north of the state capital Lansing, has long dealt with contamination left behind by the Velsicol Chemical Corporation, which manufactured pesticides in the town until 1963, when it left  and  abandoned loads of DDT in its wake. DDT, known for accumulating in food webs and persisting for decades in soil and river sediment, was banned in the U.S.  in 1972, but problems associated with its prevalent use until that time still plague the community to this day. This situation  has led to a multi-million dollar clean-up effort at taxpayers’ expense  by Environmental Protection Agency (EPA) and the Michigan Department of Environmental Quality (DEQ). EPA took control of the Velsicol plant as a Superfund site in 1982, but decades-long delays in the cleanup of the old chemical factory have left songbirds, and potentially people at risk nearly thirty years later. After years of complaints from residents, researchers  recently reported  that robins and other birds are dropping dead from DDT poisoning. The dead robins and other […]

(Beyond Pesticides June 4, 2015) Another study has found links between a commonly used household pesticide and attention deficit hyperactivity disorder (ADHD) in children and young teens. Researchers at Cincinnati Children’s Hospital Medical Center found an association between pyrethroid pesticide exposure and ADHD, particularly in terms of hyperactivity and impulsivity. These results reinforce the findings of a study led by a research team at Rutgers University earlier this year that found links between the pesticide deltamethrin and ADHD. In 2001, over concerns about adverse health consequences, the U.S.  Environmental Protection Agency banned several commonly used organophosphate (organic compounds containing phosphorus) pesticides from residential use due to the chemicals neurotoxic properties. The ban led to the increased use of pyrethroid pesticides, which are now the most commonly used pesticides for residential pest control and public health purposes. Pyrethroids, like deltamethrin, are commonly used in the home,  office buildings,  and on vegetable crops, gardens, lawns and golf courses. This shift to predominantly using pyrethroids is troubling, as they have oft been promoted as a safer choice than banned organophosphates, despite the fact that they pose many real threats to human health. Many recent studies show significant concern with this class of chemicals, […]